CytoViva combines patented enhanced darkfield optical microscopy technology with a proprietary hyperspectral imaging capability. This combination of technologies enables optical observation and spectral characterization of a wide range of nanoscale samples, including nanoparticles, pathogens and subcellular materials.
Products include:
The patented enhanced darkfield illumination system, which replaces the standard microscope condenser, provides up to 10x improved signal-to-noise optical images of nanoscale samples over standard darkfield microscopy. The system incorporates oblique angle, pre-aligned Kohler illumination. The resulting high signal-to-noise image enables direct observation of nanoscale sample elements.
The dual mode fluorescence module is a transmitted light fluorescent technique that enables real time observation of both fluorescent and non-fluorescent sample elements. This is accomplished through the proportionate mixing of fluorescence excitation light and full spectrum light.
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The hyperspectral microscope system integrates hyperspectral imaging (HSI) onto the microscope to capture spectral image files. These spectral image files can be used to spectrally characterize sample elements such as nanoparticles, pathogens or subcellular materials. Image analysis software enables mapping sample elements based upon their unique spectral fingerprint. In its most general form, hyperspectral microscopy can be used to determine the location of nanoscale materials within a sample. Analysis methods include identifying and mapping materials in composites, conducting mean spectral analysis, and comparisons of comparable materials.