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Biotech and pharma
2,497 drugmakers and biotech companies: what they’re worth, how long their cash lasts, which trials are due to read out and what the FDA has approved. From SEC filings, ClinicalTrials.gov, Drugs@FDA, FINRA and our market snapshot; prices as of Oct 19, 2026, balance sheets through Aug 31, 2026.
Market snapshot
Prices as of Oct 19, 2026. 920 of the 2,497 companies here have a listed share price; 828 have a market value that passes our checks against SEC share counts and trading volume. Best and worst lists count companies worth $300 million or more.
- Listed companies
- 920
- Combined market value
- $6.9T
- Past month, weighted by value
- +1.8%
- Past year, weighted by value
- +42.3%
Largest by market value
- Eli Lilly and Company$1.2TLLY · past year +55.9%
- Johnson & Johnson$612.9BJNJ · past year +31.6%
- AbbVie$502.0BABBV · past year +23.8%
- Merck & Co.$355.1BMRK · past year +69.8%
- Novartis$292.1BNVS · past year +14.5%
- AstraZeneca$261.6BAZN · past year −2.5%
- Amgen$231.3BAMGN · past year +43.2%
- Gilead Sciences$191.7BGILD · past year +25.9%
- Abbott Laboratories$180.8BABT · past year −19.2%
- Novo$173.2BNVO · past year −29.1%
- Pfizer$168.0BPFE · past year +20.3%
- Vertex Pharmaceuticals$127.2BVRTX · past year +20.4%
- Bristol-Myers Squibb$120.9BBMY · past year +35.6%
- GSK$100.3BGSK · past year +12.9%
- Sanofi$98.4BSNY · past year −21.6%
Best past month
- Kodiak Sciences Inc.+183.1%KOD · $5.8B
- Greenland Mines Ltd+96.1%GRML · $888.0M
- Silence Therapeutics+60.5%SLN · $2.8B
- Pacira BioSciences, Inc.+47.3%PCRX · $1.4B
- Moderna+47.1%MRNA · $90.5B
- North China Pharmaceutical Group Corp+38.2%600812.SS · $1.4B
- Iovance Biotherapeutics+35.8%IOVA · $6.3B
- Maze Therapeutics, Inc.+34.8%MAZE · $1.7B
- Xeris Biopharma Holdings, Inc.+34.6%XERS · $2.0B
- Ginkgo Bioworks+29.3%DNA · $649.2M
Worst past month
- Impact Biomedical INC.−60.5%IBO · $318.1M
- Chemomab Therapeutics Ltd.−54.4%CMMB · $684.7M
- uniQure N.V.−49.2%QURE · $1.4B
- Liquidia Corporation−48.7%LQDA · $3.1B
- BlossomHill Therapeutics, Inc.−47.1%BLSM · $432.9M
- Nektar Therapeutics−45.7%NKTR · $1.2B
- Faeth Therapeutics, Inc.−43.4%FTH · $504.3M
- Apnimed, Inc.−40.6%APMD · $716.9M
- Scribe Therapeutics, Inc.−40.5%SCTX · $371.5M
- Parabilis Medicines, Inc.−39.2%PBLS · $3.1B
Best past year
- GT Biopharma, Inc.+887.7%GTBP · $307.9M
- Moderna+771.5%MRNA · $90.5B
- Adlai Nortye Group Ltd.+585.1%ANL · $740.6M
- Kodiak Sciences Inc.+556.7%KOD · $5.8B
- Iovance Biotherapeutics+538.5%IOVA · $6.3B
- Erasca, Inc.+458.7%ERAS · $4.7B
- Climb Bio, Inc.+408.8%CLYM · $564.0M
- Twist Bioscience+399.6%TWST · $8.8B
- Galena Biopharma+396.6%SLS · $2.1B
- MBX Biosciences, Inc.+297.2%MBX · $2.5B
Worst past year
- Gossamer Bio, Inc.−95.1%GOSS · $4.2B
- SL Science Holding Ltd−85.0%SLBT · $779.5M
- Greenland Mines Ltd−81.4%GRML · $888.0M
- Tilray−80.5%TLRY · $449.3M
- KOLON Tissuegene−67.2%950160.KQ · $1.0B
- Oculis Holding AG−65.9%OCS · $482.2M
- Chemomab Therapeutics Ltd.−64.2%CMMB · $684.7M
- Evotec−63.5%EVO · $552.6M
- uniQure N.V.−61.4%QURE · $1.4B
- Impact Biomedical INC.−60.9%IBO · $318.1M
Prices and market values: our daily market snapshot of public market data (market value is the share count in the company’s latest SEC filing times the last price, or the exchange’s own figure for listings outside the U.S.). Prices are for reference only.
Cash runway
How long each money-losing company’s cash would last at its current rate of spending, from its SEC filings.
Formula. Months of runway = cash ÷ (cash used in operations over a year ÷ 12), for companies whose operating cash flow is negative.
Spending. Cash used in operations over the latest fiscal year (10-K). Where the first-quarter 10-Q after that year is on file, we roll it forward a quarter: fiscal year + this year’s first quarter − last year’s first quarter.
Cash. Cash and cash equivalents on the latest balance sheet. Most biotechs also hold short-term investments (Treasury bills, commercial paper) that the filings report separately and we don’t yet extract, so cash alone understates what many have. Current assets (cash, investments, receivables, inventory, prepaid costs) is an upper bound, so we show both and flag a company only when even its current assets cover less than 12 months.
Runway is measured from the balance-sheet date, not from today, and assumes spending stays flat. Companies raise money, cut programs and sign partnerships; this is a starting point, not a forecast.
- Listed companies burning cash
- 561
- Median runway on cash
- 8.4 months
- Median runway on current assets
- 21.6 months
- Under 12 months on current assets
- 165
Latest balance sheet on file: Aug 31, 2026. Companies whose cash flow from operations is positive are left out.
Under 12 months of runway, even counting all current assets
The 40 largest by market value of 165. The full list is in the table of every company below (sort by runway).
| Company | Market value | Cash | Current assets | Cash used in operations, a year | Runway on cash | Runway on current assets |
|---|---|---|---|---|---|---|
| Kodiak Sciences Inc.KOD | $5.8B | $125.9MJun 30, 2026 | $131.4M | $146.9M12 months to Mar 31, 2026 | 10.3 months | 10.7 months |
| Gossamer Bio, Inc.GOSS | $4.2B | $41.1MJun 30, 2026 | $72.7M | $170.3M12 months to Mar 31, 2026 | 2.9 months | 5.1 months |
| Biohaven PharmaceuticalsBHVN | $1.7B | $238.0MJun 30, 2026 | $296.6M | $594.2M12 months to Mar 31, 2026 | 4.8 months | 6.0 months |
| Replimune Group, Inc.REPL | $1.0B | $185.4MJun 30, 2026 | $200.8M | $279.1M12 months to Jun 30, 2026 | 8.0 months | 8.6 months |
| Prime Medicine, Inc.PRME | $692.9M | $47.5MJun 30, 2026 | $96.8M | $156.4M12 months to Mar 31, 2026 | 3.6 months | 7.4 months |
| CytoDyn Inc.CYDY | $368.6M | $16.4MAug 31, 2026 | $19.0M | $22.5M12 months to Aug 31, 2026 | 8.7 months | 10.1 months |
| Galectin Therapeutics IncGALT | $356.5M | $13.3MJun 30, 2026 | $14.7M | $20.1M12 months to Mar 31, 2026 | 7.9 months | 8.8 months |
| Impact Biomedical INC.IBO | $318.1M | $20.0KMar 31, 2026 | $377.0K | $1.7M12 months to Mar 31, 2026 | 0.1 months | 2.7 months |
| GT Biopharma, Inc.GTBP | $307.9M | $5.0MJun 30, 2026 | $5.8M | $13.2M12 months to Mar 31, 2026 | 4.5 months | 5.3 months |
| Quoin Pharmaceuticals Ltd.QNRX | $284.7M | $3.8MJun 30, 2026 | $11.6M | $15.8M12 months to Mar 31, 2026 | 2.9 months | 8.8 months |
| AgenusAGEN | $278.5M | $18.7MJun 30, 2026 | $78.8M | $87.5M12 months to Mar 31, 2026 | 2.6 months | 10.8 months |
| OneMedNet CorpONMD | $273.3M | $358.0KJun 30, 2026 | $1.3M | $7.2M12 months to Mar 31, 2026 | 0.6 months | 2.2 months |
| Northwest BiotherapeuticsNWBO | $264.4M | $595.0KJun 30, 2026 | $2.6M | $47.9M12 months to Mar 31, 2026 | 0.1 months | 0.6 months |
| Greenwich LifeSciences, Inc.GLSI | $220.8M | $8.9MJun 30, 2026 | $8.9M | $12.8M12 months to Mar 31, 2026 | 8.3 months | 8.3 months |
| Medicus Pharma Ltd.MDCX | $170.6M | $15.2MJun 30, 2026 | $17.0M | $27.8M12 months to Mar 31, 2026 | 6.5 months | 7.3 months |
| Korsana Biosciences, Inc.KRSA | $152.2M | $1.4MJun 30, 2026 | $1.5M | $3.5M12 months to Mar 31, 2026 | 4.7 months | 5.2 months |
| Coherus BioSciences (United States)CHRS | $151.7M | $82.9MJun 30, 2026 | $133.8M | $170.6M12 months to Mar 31, 2026 | 5.8 months | 9.4 months |
| Curanex Pharmaceuticals IncCURX | $150.6M | $2.9MJun 30, 2026 | $4.8M | $11.3M12 months to Mar 31, 2026 | 3.1 months | 5.1 months |
| Pyxis Oncology, Inc.PYXS | $146.0M | $18.9MJun 30, 2026 | $36.7M | $67.0M12 months to Mar 31, 2026 | 3.4 months | 6.6 months |
| Voyager Therapeutics (United States)VYGR | $126.6M | $35.8MJun 30, 2026 | $125.2M | $128.0M12 months to Mar 31, 2026 | 3.4 months | 11.7 months |
| Outlook Therapeutics, Inc.OTLK | $123.7M | $11.2MJun 30, 2026 | $23.2M | $55.8M12 months to Dec 31, 2025 | 2.4 months | 5.0 months |
| Semnur Pharmaceuticals, Inc.SMNR | $119.7M | $39.0KJun 30, 2026 | $1.2M | $8.1M12 months to Mar 31, 2026 | 0.1 months | 1.8 months |
| Scienture Holdings, Inc.SCNX | $119.1M | $8.2MJun 30, 2026 | $9.2M | $13.3M12 months to Mar 31, 2026 | 7.4 months | 8.3 months |
| TuHURA Biosciences, Inc./NVHURA | $112.5M | $996.0KJun 30, 2026 | $1.7M | $27.3M12 months to Mar 31, 2026 | 0.4 months | 0.7 months |
| Humacyte, Inc.HUMA | $112.3M | $79.9MJun 30, 2026 | $92.8M | $101.5M12 months to Mar 31, 2026 | 9.4 months | 11.0 months |
| GENELUX CorpGNLX | $111.5M | $9.2MJun 30, 2026 | $19.1M | $25.9M12 months to Mar 31, 2026 | 4.3 months | 8.9 months |
| Inovio PharmaceuticalsINO | $103.4M | $31.5MJun 30, 2026 | $39.9M | $83.3M12 months to Mar 31, 2026 | 4.5 months | 5.7 months |
| Atara Biotherapeutics, Inc.ATRA | $92.7M | $3.2MJun 30, 2026 | $13.5M | $25.9M12 months to Mar 31, 2026 | 1.5 months | 6.3 months |
| Insight Molecular Diagnostics Inc.IMDX | $92.6M | $17.8MJun 30, 2026 | $20.5M | $24.0M12 months to Mar 31, 2026 | 8.9 months | 10.3 months |
| Neumora Therapeutics, Inc.NMRA | $88.9M | $116.8MJun 30, 2026 | $124.9M | $193.4M12 months to Mar 31, 2026 | 7.2 months | 7.7 months |
| Neonc Technologies Holdings, INC.NTHI | $72.9M | $2.0MJun 30, 2026 | $4.2M | $21.7M12 months to Mar 31, 2026 | 1.1 months | 2.3 months |
| Cardiff Oncology, Inc.CRDF | $70.0M | $9.2MJun 30, 2026 | $35.6M | $37.4M12 months to Mar 31, 2026 | 2.9 months | 11.4 months |
| Lexaria Bioscience Corp.LEXX | $65.1M | $3.5MMay 31, 2026 | $4.1M | $8.7M12 months to Nov 30, 2025 | 4.8 months | 5.6 months |
| Oncolytics BiotechONCY | $64.0M | $4.1MJun 30, 2026 | $7.1M | $22.7M12 months to Mar 31, 2026 | 2.2 months | 3.7 months |
| Biomea Fusion, Inc.BMEA | $61.6M | $34.8MJun 30, 2026 | $36.4M | $56.4M12 months to Mar 31, 2026 | 7.4 months | 7.8 months |
| OS Therapies IncOSTX | $59.5M | $205.0KJun 30, 2026 | $3.6M | $15.4M12 months to Mar 31, 2026 | 0.2 months | 2.8 months |
| Connect Biopharma Holdings LtdCNTB | $55.8M | $27.0MJun 30, 2026 | $38.6M | $57.3M12 months to Mar 31, 2026 | 5.7 months | 8.1 months |
| IB Acquisition Corp.IBAC | $54.4M | $30.2KJun 30, 2026 | $256.5K | $2.0M12 months to Dec 31, 2025 | 0.2 months | 1.5 months |
| Gain Therapeutics, Inc.GANX | $54.3M | $13.1MJun 30, 2026 | $15.0M | $19.4M12 months to Mar 31, 2026 | 8.1 months | 9.3 months |
| Skye Bioscience, Inc.SKYE | $54.2M | $8.1MJun 30, 2026 | $11.0M | $42.4M12 months to Mar 31, 2026 | 2.3 months | 3.1 months |
Cash, current assets and operating cash flow: each company’s 10-Q and 10-K reports, from SEC EDGAR XBRL data. Click a cash figure for the filing.
Upcoming catalysts
Industry-sponsored trials with an estimated primary completion date (when the last patient’s main measurement is taken, so results usually follow within months) between Oct 21, 2026 and Apr 21, 2027. Phase 3 first, then by date. 1,507 phase 2 and phase 3 trials, 537 of them phase 3 (including phase 2/3); the first 80 are shown. Phase 1 studies are on ClinicalTrials.gov. Above them, the FDA advisory committee agenda item scheduled in the same period.
FDA advisory committee meetings
- Oct 30atropine sulfate ophthalmic solution 0.01%Dermatologic and Ophthalmic Drugs Advisory Committee · Sydnexis · NDA 219694
Advisory committees: the FDA advisory committee calendar.
Trial readouts
| Primary completion | Sponsor | Drug | Condition | Phase | Status | Record |
|---|---|---|---|---|---|---|
| Oct 22, 2026 | Amgen | DazodalibepA Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State | Sjögren's Syndrome (SS) | Phase 3 | Active not recruiting | NCT06245408 |
| Oct 22, 2026 | Roche Holding | OcrelizumabA Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis | Progressive Multiple Sclerosis (PMS) | Phase 3 | Active not recruiting | NCT03523858 |
| Oct 23, 2026 | Qilu Pharmaceutical Co., Ltd. | 3-6mg QLM1016, 10-20 mg Aripiprazole oral solution filmStudy on the Efficacy and Safety of QLM1016 in Schizophrenia | Schizophrenia | Phase 3 | Active not recruiting | NCT06799559 |
| Oct 26, 2026 | Csl Ltd | Recombinant single-chain factor VIII (rVIII-SingleChain)Recombinant Single-chain Factor VIII (rVIII-SingleChain) in Chinese Participants With Hemophilia A Previously Treated With FVIII Products | Congenital Hemophilia A | Phase 3 | Active not recruiting | NCT06738485 |
| Oct 26, 2026 | Galderma Group AG/ADR | NemolizumabA Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN) | Prurigo Nodularis | Phase 3 | Active not recruiting | NCT04204616 |
| Oct 26, 2026 | Novartis | Inclisiran sodium 300 mgCoronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic P… | Coronary Artery Disease | Phase 3 | Active not recruiting | NCT05360446 |
| Oct 28, 2026 | Akeso | Cadonilimab (AK104), SugemalimabA Study of AK104 in Subjects With Unresectable Locally Advanced NSCLC | NSCLC (Non-small Cell Lung Cancer) | Phase 3 | Recruiting | NCT06617416 |
| Oct 28, 2026 | Albireo, an Ipsen Company | OdevixibatAn Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia | Biliary Atresia | Phase 3 | Active not recruiting | NCT05426733 |
| Oct 28, 2026 | Roche Holding | RO7204239, RisdiplamA Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular A… | Spinal Muscular Atrophy (SMA) | Phase 2/3 | Active not recruiting | NCT05115110 |
| Oct 28, 2026 | Merck & Co. | Belzutifan, PembrolizumabA Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Ca… | Carcinoma, Renal Cell | Phase 3 | Active not recruiting | NCT05239728 |
| Oct 29, 2026 | Roche Holding | AfimkibartA Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to … | Moderately to Severely Active Ulcerative Colitis | Phase 3 | Active not recruiting | NCT06588855 |
| Oct 29, 2026 | Novartis | Ianalumab, CorticosteroidsStudy of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP) | Primary Immune Thrombocytopenia (ITP) | Phase 3 | Active not recruiting | NCT05653349 |
| Oct 30, 2026 | CSPC Pharmaceutical Group | –A Study of Prusogliptin Tablets Combined With Dapagliflozin Tablets and Metformin Hydrochloride Extended Release Tablets in Type 2 Diabetes | Type 2 Diabetes | Phase 3 | Active not recruiting | NCT07026968 |
| Oct 30, 2026 | Kind Pharmaceuticals LLC | AND017 capsules, ESAA Study of AND017 to Evaluate Efficacy and Safety in Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Patients With Anemia | Anemia Due to Chronic Kidney Disease | Phase 3 | Recruiting | NCT07494409 |
| Oct 30, 2026 | Laekna Limited | AfuresertibStudy to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer | Breast Cancer | Phase 3 | Active not recruiting | NCT04851613 |
| Oct 30, 2026 | Natureceuticals Sdn Bhd | Nuvastatic 300Nuvastatic® Phase III Trial for Fatigue in Triple-Negative Breast Cancer | Fatigue Related to Cancer Treatment, Breast Cancer | Phase 3 | Recruiting | NCT07669467 |
| Oct 30, 2026 | Pfizer | Encorafenib, Binimetinib, PembrolizumabA Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma | Melanoma | Phase 3 | Active not recruiting | NCT04657991 |
| Oct 30, 2026 | Vertex Pharmaceuticals | VX-121/TEZ/D-IVAA Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy | Cystic Fibrosis | Phase 3 | Active not recruiting | NCT05444257 |
| Oct 31, 2026 | AstraZeneca | Capivasertib, FulvestrantCapivasertib+Fulvestrant asTreatment for Locally Advanced(Inoperable) or Metastatic HR+/HER2- Breast Cancer in Chinese Patients | Breast Cancer | Phase 3 | Active not recruiting | NCT06635447 |
| Oct 31, 2026 | Jiangsu Hengrui Medicine | SHR6390Phase III Study :SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Rec… | Hormone Receptor Positive,Human Epidermal Receptor 2 Negative, Node-positive, High Risk, Early Stage,Female Breast Cancer | Phase 3 | Active not recruiting | NCT04842617 |
| Oct 31, 2026 | Longboard Pharmaceuticals, Inc. | LP352A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE) | Developmental and Epileptic Encephalopathy | Phase 3 | Active not recruiting | NCT06719141 |
| Oct 31, 2026 | Natureceuticals Sdn Bhd | Nuvastatic 300A Randomized, Double-blind, Placebo-controlled, Parallel-group, Comparative, Phase III Study to Evaluate the Efficacy and Safety of Nuvastat… | Fatigue Related to Cancer Treatment, Colon Cancer | Phase 3 | Recruiting | NCT07669454 |
| Oct 31, 2026 | Olema Pharmaceuticals, Inc. | Palazestrant, Fulvestrant, Anastrozole and 2 moreOP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer | Breast Cancer, Advanced Breast Cancer and 3 more | Phase 3 | Active not recruiting | NCT06016738 |
| Oct 31, 2026 | Sarepta Therapeutics | EteplirsenA Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON) | Muscular Dystrophy, Duchenne | Phase 3 | Active not recruiting | NCT03992430 |
| Oct 31, 2026 | TG Therapeutics | UblituximabA Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, Radiological and Clinical Effects of Subcutaneous Ublituximab in Partici… | Relapsing Multiple Sclerosis | Phase 3 | Active not recruiting | NCT07211633 |
| Oct 31, 2026 | Takeda Pharmaceutical Company | TAK-788, Pemetrexed, Cisplatin and 1 moreTAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutati… | Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) | Phase 3 | Active not recruiting | NCT04129502 |
| Oct 31, 2026 | Teva Pharmaceutical Industries Ltd. | TEV-56248, Albuterol sulfateA Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations | Asthma | Phase 3 | Active not recruiting | NCT06052267 |
| Oct 31, 2026 | UCB | Staccato alprazolamA Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged … | Stereotypical Prolonged Seizures | Phase 3 | Recruiting | NCT05077904 |
| Nov 2026 | AbbVie | Upadacitinib 15mg Dose, Dupilumab 300mg Dose, Upadacitinib 30mg DoseA Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab | Atopic Dermatitis | Phase 3 | Active not recruiting | NCT06389136 |
| Nov 2026 | Akeso | cadonilimab, pulocimab, paclitaxelA Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma | Gastric and Gastroesophageal Junction Adenocarcinoma | Phase 3 | Recruiting | NCT06341335 |
| Nov 2026 | CG Oncology, Inc. | Cretostimogene Grenadenorepvec, n-dodecyl-B-D-maltosideA Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT | Non Muscle Invasive Bladder Cancer, Urologic Cancer and 2 more | Phase 3 | Active not recruiting | NCT06111235 |
| Nov 2026 | Camurus | CAM2029, Octreotide LAR, Lanreotide ATGA Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET | Gastro-enteropancreatic Neuroendocrine Tumor | Phase 3 | Active not recruiting | NCT05050942 |
| Nov 2026 | Colgate-Palmolive Company | Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TBTo Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis. | Plaque, Dental, Gingivitis | Phase 3 | Active not recruiting | NCT07605338 |
| Nov 2026 | DBV Technologies | DBV712 250 mcgSafety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers) | Allergy, Peanut Allergy | Phase 3 | Active not recruiting | NCT07003919 |
| Nov 2026 | Eli Lilly and Company | TirzepatideA Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight | Type 1 Diabetes, Obesity and 1 more | Phase 3 | Active not recruiting | NCT06962280 |
| Nov 2026 | Eli Lilly and Company | TirzepatideA Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight | Type 1 Diabetes, Obesity and 1 more | Phase 3 | Active not recruiting | NCT06914895 |
| Nov 2026 | Eli Lilly and Company | Retatrutide, TirzepatideA Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity | Obesity | Phase 3 | Active not recruiting | NCT06662383 |
| Nov 2026 | Immunic AG | IMU-838 tabletsStudy to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting | Phase 3 | Active not recruiting | NCT05201638 |
| Nov 2026 | Immunic AG | IMU-838 tabletsStudy to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis | Multiple Sclerosis | Phase 3 | Active not recruiting | NCT05134441 |
| Nov 2026 | Lynk Pharmaceuticals Co., Ltd | LNK01001A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing Spondylitis | Ankylosing Spondylitis | Phase 3 | Recruiting | NCT07237568 |
| Nov 2026 | Medicure Inc | Pyridoxal PhosphateOral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency | Pyridox(am)Ine 5'-Phosphate Oxidase Deficiency | Phase 3 | Recruiting | NCT04706013 |
| Nov 2026 | Nanjing Chia-tai Tianqing Pharmaceutical | NTQ5082 capsules 200 mg, Eculizumab InjectionA Phase III Study of NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients | Paroxysmal Nocturnal Hemoglobinuria | Phase 3 | Not yet recruiting | NCT07177859 |
| Nov 2026 | NewAmsterdam Pharma Co N.V. | ObicetrapibCardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease | Atherosclerotic Cardiovascular Disease | Phase 3 | Active not recruiting | NCT05202509 |
| Nov 2026 | Nuance Hearing | Spectacle Hearing AidA Prospective, Open-label, Pivotal Study to Assess Spectacle Hearing Aid Safety and Efficacy | Hearing Loss Mixed | Phase 2/3 | Recruiting | NCT07282028 |
| Nov 2026 | Sandoz | CYB704, Ocrevus-EU, Ocrevus-USComparative PK, PD, Efficacy, and Safety Assessment of the Proposed Ocrelizumab Biosimilar CYB704 and Ocrevus in Participants With Relapsing… | Relapsing Multiple Sclerosis | Phase 3 | Active not recruiting | NCT06847724 |
| Nov 2026 | Sichuan Baili Pharmaceutical Co., Ltd. | BL-B01D1, capecitabine, gemcitabine and 1 moreA Study Comparing BL-B01D1 With Physician's Choice of Chemotherapy in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma(PANKU-N… | Nasopharyngeal Carcinoma | Phase 3 | Active not recruiting | NCT06118333 |
| Nov 2026 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | SKB264, PembrolizumabA Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung… | Non-Small Cell Lung Cancer | Phase 3 | Active not recruiting | NCT06448312 |
| Nov 2026 | Sinovac Biotech | experimental vaccine, active comparator vaccinePhase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 2-6 Years | Epidemic Meningitis, Meningococcal Vaccines | Phase 3 | Active not recruiting | NCT07505888 |
| Nov 2026 | Waterstone Pharmaceutical (Wuhan) Co., LTD. | WS016A Two-Part, Phase 3 Study Evaluating the Efficacy and Safety of WS016 for the Treatment of Hyperkalemia | Hyperkalemia | Phase 3 | Recruiting | NCT07251309 |
| Nov 2026 | Wooshin Labottach Co., Ltd. | Cosmetic patch containing urea applicated daily for 3 monthsStudy to Assess Efficacy, Safety and Tolerability of a Nail Patch in Patients With Nail Fragility, Mychosis, Psoriasis | Nail Psoriasis, Nail Damage and 1 more | Phase 3 | Recruiting | NCT07029516 |
| Nov 2026 | medac GmbH | MethotrexateEfficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis. | Moderate to Severe Atopic Dermatitis | Phase 3 | Recruiting | NCT06239311 |
| Nov 1, 2026 | Bristol-Myers Squibb | KarXTA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder | Bipolar-I Disorder With Mania or Mania With Mixed Features | Phase 3 | Recruiting | NCT06951698 |
| Nov 1, 2026 | Epygenix | Clemizole HClAn Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome | Lennox Gastaut Syndrome | Phase 3 | Recruiting | NCT05066217 |
| Nov 1, 2026 | Scholar Rock, Inc. | ApitegromabLong-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab | Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3 and 8 more | Phase 3 | Active not recruiting | NCT05626855 |
| Nov 2, 2026 | AstraZeneca | AnifrolumabA Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus | Cutaneous Lupus Erythematosus | Phase 3 | Active not recruiting | NCT06015737 |
| Nov 2, 2026 | Bristol-Myers Squibb | KarXTA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2) | Bipolar Disorder Type I With Mania or Mania With Mixed Features | Phase 3 | Recruiting | NCT06951711 |
| Nov 2, 2026 | Teva Pharmaceutical Industries Ltd. | Fp/ABS, FP, ABSA Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Parti… | Asthma | Phase 3 | Active not recruiting | NCT06664619 |
| Nov 3, 2026 | Novartis | LOU064 (blinded)24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and … | Chronic Spontaneous Urticaria | Phase 3 | Active not recruiting | NCT05677451 |
| Nov 4, 2026 | CMG Pharmaceutical Co. Ltd | CMG190303(Dapagliflozin/Rosuvastatin)Evaluate the Efficacy and Safety of CMG190303 in Patients With Type 2 Diabetes and Dyslipidemia | Dyslipidemia, Type 2 Diabetes | Phase 3 | Recruiting | NCT06772168 |
| Nov 9, 2026 | LEAF4Life, Inc. | LEAF-4L6715, Supportive CareEfficacy and Safety of LEAF-4L6715 for Acute Respiratory Distress Syndrome | Acute Respiratory Distress Syndrome | Phase 3 | Not yet recruiting | NCT06640777 |
| Nov 10, 2026 | Gan & Lee Pharmaceuticals Co., Ltd. | GZR4, Insulin Icodec groupA Phase IIIb Clinical Study to Assess the Efficacy and Safety of GZR4 in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin | Diabetes | Phase 3 | Recruiting | NCT07165223 |
| Nov 10, 2026 | LaNova Medicines Zhejiang Co., Ltd. | LM-302, Apatinib, IrinotecanLM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma. | Locally Advanced or Metastatic GC and GCJ Adenocarcinoma | Phase 3 | Active not recruiting | NCT06351020 |
| Nov 11, 2026 | AstraZeneca | Trastuzumab deruxtecan, Taxane, Pertuzumab and 1 moreTrastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cance… | Breast Cancer; HER2-positive; Metastatic | Phase 3 | Active not recruiting | NCT04784715 |
| Nov 11, 2026 | Tasly Pharmaceutical Group Co., Ltd | Changkang granulesEfficacy and Safety of Changkang Granules in the Treatment of Irritable Bowel Syndrome With Predominant Diarrhea (Liver qi Affecting the Spl… | Diarrhea-predominant Irritable Boewl Syndrome | Phase 3 | Not yet recruiting | NCT06753890 |
| Nov 12, 2026 | Qilu Pharmaceutical Co., Ltd. | RelugolixEfficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids | Heavy Menstrual Bleeding, Uterine Fibroids | Phase 3 | Recruiting | NCT06671548 |
| Nov 13, 2026 | Roche Holding | Inavolisib, Fulvestrant, Alpelisib and 3 moreA Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-P… | Breast Cancer | Phase 3 | Recruiting | NCT05646862 |
| Nov 14, 2026 | BrightGene Bio-Medical Technology Co. | 5 mg BGM0504 Administered SC, 10 mg BGM0504 Administered SC, Semaglutide Administered SCA Study of BGM0504 in Participants With Type 2 Diabetes | Type 2 Diabetes Mellitus (T2DM) | Phase 3 | Active not recruiting | NCT06716216 |
| Nov 14, 2026 | BrightGene Bio-Medical Technology Co. | 5 mg BGM0504 Administered SC, : 10 mg BGM0504 Administered SCA Study of BGM0504 in Poorly Controlled Type 2 Diabetes Patients Only Through Diet and Exercise | Type 2 Diabetes Mellitus (T2DM) | Phase 3 | Active not recruiting | NCT06716203 |
| Nov 15, 2026 | Achieve Life Sciences, INC. | Cytisinicline, Behavioral SupportPhase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes | Vaping Cessation | Phase 3 | Not yet recruiting | NCT07392125 |
| Nov 16, 2026 | UCB | ZilucoplanA Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis | Generalized Myasthenia Gravis | Phase 2/3 | Recruiting | NCT06055959 |
| Nov 18, 2026 | Bristol-Myers Squibb | DeucravacitinibA Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome | Sjögren's Syndrome | Phase 3 | Active not recruiting | NCT05946941 |
| Nov 18, 2026 | Han Xu, M.D., Ph.D., FAPCR, Medical Director,, IRB Chair | ETOPOSIDE - Usual, ETOPOSIDE - StudyPharmacogenomics ANDA SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms | Small Cell Lung Cancer | Phase 2/3 | Active not recruiting | NCT01064466 |
| Nov 18, 2026 | Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair | Abiraterone - Usual, Abiraterone - StudyPharmacogenomics IND Commercial SNP Clinical Study - Abiraterone and Single Nucleotide Polymorphisms | Prostate Cancer | Phase 2/3 | Active not recruiting | NCT03348670 |
| Nov 18, 2026 | Medicine Invention Design, Inc | ALECENSA - alectinib hydrochloride capsulePharmacogenomics IND SNP Clinical Trial - Alectinib and Single Nucleotide Polymorphisms | ALK-Positive Non-Small Cell Lung Cancer (NSCLC) | Phase 2/3 | Active not recruiting | NCT05987956 |
| Nov 20, 2026 | Merck & Co. | Pembrolizumab, Carboplatin, Paclitaxel and 5 moreStudy of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed… | Endometrial Neoplasms | Phase 3 | Active not recruiting | NCT04634877 |
| Nov 21, 2026 | Changchun GeneScience Pharmaceutical Co., Ltd. | Cabergoline tablets, Bromocriptine mesylate tabletsA Phase III Clinical Study of Cabergoline Tablets Compared With Bromocriptine Mesylate Tablets | Hyperprolactinemia | Phase 3 | Recruiting | NCT07124221 |
| Nov 23, 2026 | GSK | dTpaA Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healt… | Diphtheria-Tetanus-acellular Pertussis Vaccines | Phase 3 | Active not recruiting | NCT07596199 |
| Nov 23, 2026 | GSK | Investigational varicella vaccine, Marketed varicella vaccine, Measles, mumps, and rubella vaccine and 4 moreA Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age | Chickenpox | Phase 3 | Recruiting | NCT06693895 |
| Nov 24, 2026 | Merck KGaA | AvelumabAvelumab Program Rollover Study | Solid Tumors | Phase 3 | Active not recruiting | NCT03815643 |
| Nov 24, 2026 | HTA Co., Ltd. | 177Lu-DOTATATE injection, Octreotide LAR (Long-acting release)A Phase III Clinical Study to Compare the Safety and Efficacy of 177Lu-DOTATATE Injection and Long-acting Oxytrexine in Adult Patients With … | NETS Ga68 Lu177 | Phase 3 | Recruiting | NCT07057622 |
Trials: ClinicalTrials.gov, the U.S. National Library of Medicine’s registry, industry-sponsored studies only. Completion dates are the sponsor’s own estimates and often slip. Retrieved Oct 21, 2026.
Recent FDA approvals
Original approvals of new drug applications (NDAs) and biologics license applications (BLAs) in the 12 months to Oct 16, 2026, newest first: 139 in all, 59 of them new molecular entities (the FDA’s type 1, for drugs and biologics alike). Supplements (new uses, doses and labeling changes) are left out, as are 690 first approvals of generics (ANDAs).
New molecular entities
- Oct 9Hovilpr (pritelivir)NDAPriority reviewAicuris Anti-infective Cures Ag
- Sep 28Emcitate (tiratricol)NDAPriority reviewOrphan drugRare Thyroid
- Sep 25
- Sep 25Atebrioz (zilurgisertib fumarate)NDAPriority reviewOrphan drugMirum Pharmaceuticals
- Sep 23Onswik (insulin efsitora alfa-gobe)BLAEli Lilly and Company
- Sep 23Lyrfigtu (lirafugratinib hydrochloride)NDAPriority reviewOrphan drugElevar
- Sep 11Isembyld (apitegromab-mstn)BLAPriority reviewOrphan drugScholar Rock Inc
- Sep 11Pixclara (floretyrosine f-18)NDAPriority reviewOrphan drugTelix Pharmaceuticals Limited
- Sep 4Etcamah (camizestrant)NDAAstraZeneca
- Sep 3Zanvastro (zilganersen sodium)NDAPriority reviewOrphan drugIonis Pharmaceuticals Inc
- Aug 28Mimrylo (rusfertide acetate)NDAPriority reviewOrphan drugTakeda Pharmaceutical Company
- Aug 27Lisraya (brepocitinib tosylate)NDAPriority reviewOrphan drugPriovant Therap
- Aug 26Rasonque (daraxonrasib)NDAPriority reviewOrphan drugRevolution Medicines
- Aug 19Pasatru (garetosmab-grts)BLAPriority reviewOrphan drugRegeneron Pharmaceuticals
- Aug 13Tauklarify (florquinitau f-18)NDACerveau Lantheus
- Aug 13Zenbexus (iberdomide hydrochloride)NDAPriority reviewOrphan drugBristol-Myers Squibb
- Aug 5Orzeyful (oveporexton)NDAPriority reviewOrphan drugTakeda Pharmaceutical Company
- Jul 24Lytenava (bevacizumab-vikg)BLAOutlook Therapeutics, Inc.
- Jul 24Simtriyo (centanafadine hydrochloride)NDAPriority reviewOtsuka Pharmaceutical
- Jul 22Jideytro (zidesamtinib)NDAOrphan drugNuvalent
- Jul 15Lipfendra (enlicitide decanoate)NDAPriority reviewMerck & Co.
- Jul 14Revtorpyk (gedatolisib)NDAPriority reviewCelcuity Inc.
- Jul 7Trutakna (atacicept-vymj)BLAPriority reviewVera Therapeutics, Inc.
- Jun 26Lumvoa (veligrotug-vvze)BLAPriority reviewViridian Therapeutics, Inc.\DE
- Jun 17
- Jun 12
- May 29Zaynich (cefepime hydrochloride; zidebactam)NDAPriority reviewWockhardt Bio Ag
- May 29Cypsedo (cipepofol)NDAHaisco
- May 29
- May 27
- May 22Hepcludex (bulevirtide-gmod)BLAPriority reviewOrphan drugGilead Sciences
- May 15Baxfendy (baxdrostat)NDAPriority reviewAstraZeneca
- May 13Beqalzi (sonrotoclax)NDAPriority reviewOrphan drugBeOne Medicines Ltd.
- May 1Veppanu (vepdegestrant)NDARigel Pharmaceuticals Inc
- Apr 20Idvynso (doravirine; islatravir)NDAMerck & Co.
- Apr 1Foundayo (orforglipron calcium)NDAEli Lilly and Company
- Mar 26Awiqli Flextouch (insulin icodec)BLAOrphan drugNovo
- Mar 25Lifyorli (copackaged) (relacorilant)NDACorcept Therapeutics
- Mar 24Avlayah (tividenofusp alfa-eknm)BLAPriority reviewOrphan drugDenali Therapeutics Inc.
- Mar 17Lynavoy (linerixibat)NDAOrphan drugIntercept Pharmaceuticals
- Mar 17Icotyde (icotrokinra hydrochloride)NDAPriority reviewJohnson & Johnson
- Feb 27Yuviwel (navepegritide)NDAPriority reviewOrphan drugAscendis
- Feb 23Loargys (pegzilarginase-nbln)BLAPriority reviewOrphan drugImmedica Pharma AB
- Feb 20Bysanti (milsaperidone)NDAVanda Pharmaceuticals Inc.
- Feb 12Adquey (difamilast)NDAAcrotech Biopharma
- Jan 12Zycubo (copper histidinate)NDAPriority reviewOrphan drugSentynl Theraps Inc
- Dec 30Nereus (tradipitant)NDAVanda Pharmaceuticals Inc.
- Dec 23Yartemlea (narsoplimab-wuug)BLAPriority reviewOrphan drugOmeros Corp
- Dec 19Myqorzo (aficamten)NDAOrphan drugCytokinetics
- Dec 16
- Dec 12Nuzolvence (zoliflodacin)NDAPriority reviewEntasis Therapeutics
- Dec 12Lerochol (lerodalcibep-liga)BLALib Therapeutics, Inc.
- Dec 12Cardamyst (etripamil)NDAMilestone Pharmaceuticals Inc.
- Nov 25Voyxact (sibeprenlimab-szsi)BLAPriority reviewOtsuka Pharmaceutical
- Nov 19
- Nov 18Redemplo (plozasiran sodium)NDAOrphan drugArrowhead Pharmaceuticals
- Nov 13Komzifti (ziftomenib)NDAPriority reviewOrphan drugKura
- Nov 3
- Oct 24
Other original approvals
New dosage forms, formulations, combinations, new active ingredients and biosimilars; the latest 40 of 80.
| Approved | Product | Sponsor | Kind |
|---|---|---|---|
| Oct 16 | Brytlybrytly (apraclonidine) | Alcon | New formulation or new manufacturer |
| Oct 15 | Evoxaccevimeline hydrochloride | Cosette Pharms Nc | New dosage form |
| Oct 9 | Isovue Readiiopamidol | Bracco | New formulation or new manufacturer |
| Oct 8 | Breztri Aerospherebudesonide, glycopyrrolate, and formoterol fumarate | AstraZeneca | New formulation or new manufacturer |
| Oct 8 | Weltruzaolanzapine | Teva Pharmaceutical Industries Ltd. | New formulation or new manufacturer |
| Oct 1 | Trabectedintrabectedin | Ever | New formulation or new manufacturer |
| Sep 25 | Zueinodiclofenac sodium | Adventapharma | New formulation or new manufacturer |
| Sep 25 | Degevmadenosumab-adet | Teva Pharmaceutical Industries Ltd. | New formulation or new manufacturer |
| Sep 25 | Lamliquelamotrigine hemifumarate | Azurity | New active ingredient |
| Sep 15 | Garzulysinsulin aspart-fsan | Emerge Bioscience Pte. Ltd. | BLA |
| Sep 14 | Bexlutrylutetium lu-177 dotatate | Curium | New formulation or new manufacturer |
| Sep 3 | Omcaziocabozantinib laurylsulfate | Handa Oncol | New formulation or new manufacturer |
| Aug 27 | Bixlenvo Sunlenca Starter Pack (copackaged)bictegravir sodium, lenacapavir sodium; lenacapavir sodium | Gilead Sciences | New combination |
| Aug 27 | Bixlenvobictegravir sodium; lenacapavir sodium | Gilead Sciences | New combination |
| Aug 26 | Vobrigleuprolide acetate | Sun Pharmaceutical | New formulation or new manufacturer |
| Aug 14 | Sodium Bicarbonatesodium bicarbonate | Baxter International | New formulation or new manufacturer |
| Jul 31 | Zimrixbyrituximab-cdxx | Dr Reddys Labs Sa | BLA |
| Jul 29 | Qlonilikclonidine hydrochloride | Cmp Dev Llc | New formulation or new manufacturer |
| Jul 29 | Glycophossodium glycerophosphate | Fresenius Kabi | New active ingredient |
| Jul 28 | Gwyn Loethinyl estradiol; norelgestromin | Viatris | New formulation or new manufacturer |
| Jul 24 | Tylenol With Naproxenacetaminophen; naproxen sodium | Kenvue | New combination |
| Jul 24 | Garzulysinsulin aspart-fsan | Emerge Bioscience Pte. Ltd. | BLA |
| Jul 10 | Zyogreenindocyanine green | Provepharm Sas | New dosage form |
| Jul 9 | Sarclisa Escenaisatuximab-irfc | Sanofi | New dosage form |
| Jul 9 | Sodium Bicarbonatesodium bicarbonate | Amneal Pharmaceuticals, Inc. | New formulation or new manufacturer |
| Jun 24 | Navitruxfosaprepitant dimeglumine | Avyxa Holdings | New formulation or new manufacturer |
| Jun 16 | Aprepitantaprepitant | Azurity | New formulation or new manufacturer |
| Jun 2 | Tiocystintiopronin | Casper Pharma Llc | New formulation or new manufacturer |
| Jun 2 | Ranluspecranibizumab-hkdz | Lupin Ltd. | New active ingredient |
| May 29 | Cavhanzanilotinib | Cycle | New formulation or new manufacturer |
| May 22 | Differin Epiduo Acne Gel (adapalene And Benzoyl Peroxide)adapalene, benzoyl peroxide; adapalene; benzoyl peroxide | Galderma Group AG/ADR | Partial rx to otc switch |
| May 15 | Immgolisgolimumab-sldi | Accord Biopharma Inc. | New formulation or new manufacturer |
| May 14 | Trimbowbeclomethasone dipropionate; formoterol fumarate; glycopyrrolate | Chiesi | New combination |
| May 7 | Ennumopegfilgrastim-pccg | Accord Biopharma Inc. | BLA |
| May 1 | Jakafi Xrruxolitinib phosphate | Incyte | New formulation or new manufacturer |
| May 1 | Evditrabectedin | Apotex | New formulation or new manufacturer |
| Apr 29 | Langlarainsulin glargine-aldy | Sunshine Lake Pharma Co Ltd | BLA |
| Apr 24 | Saphneloanifrolumab-fnia | AstraZeneca | New formulation or new manufacturer |
| Mar 30 | Epinephrineepinephrine | Baxter International | New combination and new formulation or new manufacturer |
| Mar 27 | Ponlimsidenosumab-adet | Teva Pharmaceutical Industries Ltd. | New formulation or new manufacturer |
Approvals: Drugs@FDA, the FDA’s database of approved drugs and biologics reviewed by its drug center (CDER). Vaccines and blood products reviewed by CBER are not in it.
Insider buying
Open-market purchases of shares from Jul 23, 2026 to Oct 21, 2026: 271 filings at 101 companies, $633.1M in all, by trade date. Each row is one Form 4; click the value for the filing.
Officers and directors
The largest 25 of 225 purchases by people who run the company or sit on its board (some also own 10% or more).
| Company | Buyer | Date | Shares | Value |
|---|---|---|---|---|
| Kodiak Sciences Inc.KOD | 667, L.P.Director, 10% owner | Sep 28–Sep 29 | 715,592 | $63.4M |
| Kodiak Sciences Inc.KOD | Baker Bros. Advisors (GP) LLCDirector, 10% owner | Sep 28 | 807,840 | $58.6M |
| Scribe Therapeutics, Inc.SCTX | Avoro Ventures LLCDirector | Jul 24–Jul 28 | 2,391,238 | $36.3M |
| Kodiak Sciences Inc.KOD | BAKER JULIANDirector, 10% owner | Sep 28 | 418,323 | $35.0M |
| Braveheart Bio, Inc.BRVE | Chimovits Erez; OrbiMed Genesis GP LLCDirector, 10% owner | Aug 7 | 1,940,000 | $34.9M |
| Electra Therapeutics, Inc.ETRA | GORDON CARL L; OrbiMed Capital GP VII LLCDirector, 10% owner | Sep 21 | 1,333,333 | $20.0M |
| ADARx Pharmaceuticals, Inc.ADRX | GORDON CARL L; OrbiMed Genesis GP LLCDirector, 10% owner | Sep 28 | 950,000 | $16.1M |
| Scribe Therapeutics, Inc.SCTX | GORDON CARL L; ORBIMED ADVISORS LLCDirector | Jul 27 | 1,000,000 | $15.0M |
| Alumis INC.ALMS | AKKARAJU SRINIVASDirector | Sep 4–Sep 8 | 986,721 | $10.7M |
| Attovia Therapeutics, Inc.ATTO | WALSH COLIN; GOLDMAN SACHS ASSET MANAGEMENT, L.P. and 1 moreDirector | Aug 5–Aug 6 | 585,000 | $10.3M |
| BlossomHill Therapeutics, Inc.BLSM | GORDON CARL L; OrbiMed Capital GP VIII LLCDirector | Aug 10 | 625,000 | $10.0M |
| Apollomics Inc.APLM | Chen Hung-WenChief Executive Officer, Director | Aug 14 | 536,667 | $7.6M |
| Immatics N.V.IMTX | EDELMAN JOSEPHDirector | Aug 26 | 863,060 | $7.5M |
| Inhibrx Biosciences, Inc.INBX | Lappe MarkChief Executive Officer, Director | Sep 8 | 25,000 | $2.6M |
| Outlook Therapeutics, Inc.OTLK | Sukhtian Ghiath M.Director, 10% owner | Aug 12 | 2,525,252 | $2.5M |
| Braveheart Bio, Inc.BRVE | Viehbacher Christopher; Murdoch TravisDirector | Aug 7 | 83,333 | $1.5M |
| Helus Pharma Inc.HELP | Halstead MichaelChief Executive Officer | Sep 21 | 100,000 | $1.3M |
| Helus Pharma Inc.HELP | Glavine Paul; So Eric H. L.Chief Growth Officer | Sep 8 | 100,000 | $1.2M |
| Kura OncologyKURA | WILSON TROY EDWARDPresident and CEO, Director | Aug 24 | 100,000 | $1.2M |
| Helus Pharma Inc.HELP | So Eric H. L.Executive Chair, Director | Sep 4 | 100,000 | $1.2M |
| Helus Pharma Inc.HELP | Glavine PaulChief Growth Officer | Sep 3 | 100,000 | $1.2M |
| Helus Pharma Inc.HELP | So Eric H. L.Executive Chair, Director | Sep 1 | 95,000 | $1.1M |
| Kura OncologyKURA | WILSON TROY EDWARDPresident and CEO, Director | Aug 17 | 100,000 | $1.1M |
| Ionis Pharmaceuticals IncIONS | Hayden Michael RDirector | Jul 30–Jul 31 | 20,000 | $1.1M |
| ADARx Pharmaceuticals, Inc.ADRX | Chimovits ErezDirector | Sep 28 | 61,516 | $1.0M |
Large shareholders
The largest 25 of 46 purchases by owners of 10% or more with no board seat, usually venture and hedge funds, often buying in a stock sale or IPO.
| Company | Buyer | Date | Shares | Value |
|---|---|---|---|---|
| Braveheart Bio, Inc.BRVE | Forbion Growth Opportunities Fund III Cooperatief U.A.10% owner | Aug 7 | 3,600,000 | $64.8M |
| MapLight Therapeutics, Inc.MPLT | Catalyst4, Inc.10% owner | Aug 14 | 4,400,000 | $50.1M |
| ADARx Pharmaceuticals, Inc.ADRX | SR ONE CAPITAL MANAGEMENT, LLC; George Simeon10% owner | Sep 28 | 1,600,000 | $27.2M |
| Braveheart Bio, Inc.BRVE | Andreessen Marc L10% owner | Aug 7 | 1,100,000 | $19.8M |
| MapLight Therapeutics, Inc.MPLT | Catalyst4, Inc.10% owner | Jul 28–Jul 30 | 1,209,225 | $15.3M |
| Zentalis Pharmaceuticals, Inc.ZNTL | WALTERS WILLIAM THURMAN10% owner | Aug 14 | 4,335,000 | $15.2M |
| Attovia Therapeutics, Inc.ATTO | Green Jeremy10% owner | Aug 6 | 600,000 | $10.2M |
| Attovia Therapeutics, Inc.ATTO | FHMLS XI, L.P.10% owner | Aug 6 | 588,235 | $10.0M |
| Attovia Therapeutics, Inc.ATTO | venBio Global Strategic Fund IV, L.P.10% owner | Aug 6 | 382,352 | $6.5M |
| Attovia Therapeutics, Inc.ATTO | Sanofi10% owner | Aug 6 | 300,000 | $5.1M |
| Apnimed, Inc.APMD | Morningside Venture Investments Ltd10% owner | Aug 3 | 312,500 | $5.0M |
| BlossomHill Therapeutics, Inc.BLSM | Cormorant Private Healthcare Fund VI, LP10% owner | Aug 10 | 312,500 | $5.0M |
| Scribe Therapeutics, Inc.SCTX | AH Equity Partners Bio II, L.L.C.10% owner | Jul 27 | 333,333 | $5.0M |
| Sol-Gel Technologies Ltd.SLGL | Opaleye Management Inc.10% owner | Aug 28–Aug 31 | 40,330 | $2.8M |
| Latigo Biotherapeutics, Inc.LTGO | Foresite Capital Fund VI LP; Tananbaum James B.10% owner | Aug 10 | 140,000 | $2.5M |
| Nature's Sunshine ProductsNATR | PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C.10% owner | Aug 6–Aug 10 | 141,389 | $2.3M |
| Tenax Therapeutics, INC.TENX | Schneeberger Daniel10% owner | Aug 20–Aug 24 | 1,025,867 | $1.8M |
| NextCure, Inc.NXTC | ADAR1 Capital Management, LLC10% owner | Jul 30–Jul 31 | 329,153 | $1.6M |
| Tenax Therapeutics, INC.TENX | ADAR1 Capital Management, LLC10% owner | Sep 3 | 900,000 | $1.6M |
| Prothena Corp Public Ltd CoPRTA | SCULLY WILLIAM P10% owner | Sep 29 | 162,000 | $1.4M |
| Tenax Therapeutics, INC.TENX | Schneeberger Daniel10% owner | Aug 31–Sep 2 | 770,333 | $1.4M |
| Alpha Cognition Inc.ACOG | Opaleye Management Inc.10% owner | Sep 14–Sep 16 | 123,918 | $1.1M |
| Eikon Therapeutics, Inc.EIKN | Kutzkey Tim10% owner | Sep 3 | 89,200 | $1.0M |
| Prothena Corp Public Ltd CoPRTA | SCULLY WILLIAM P10% owner | Sep 28 | 103,500 | $890.1K |
| Prothena Corp Public Ltd CoPRTA | SCULLY WILLIAM P10% owner | Sep 18 | 100,000 | $843.0K |
Insider trades: Form 4 filings on SEC EDGAR. Open-market purchases (transaction code P) of shares only, not options or grants.
Most shorted
Short interest as a share of all shares outstanding, as of FINRA’s Sep 30, 2026 report, for the 30 most shorted U.S.-listed companies here worth $300 million or more. Change is from the previous report, two weeks earlier.
| Company | Of shares | Shares short | Change | Days to cover | Market value |
|---|---|---|---|---|---|
| C4 Therapeutics (United States)CCCC | 32.8% | 40,395,665 | +0.5% | 17.6 | $354.9M |
| Capricor Therapeutics, INC.CAPR | 32.4% | 18,825,352 | −4.3% | 4.5 | $385.8M |
| Intellia TherapeuticsNTLA | 32.2% | 45,110,513 | −3.4% | 9.5 | $1.6B |
| Recursion PharmaceuticalsRXRX | 29.5% | 157,938,412 | −11.6% | 6.1 | $1.9B |
| NovavaxNVAX | 27.9% | 46,046,946 | −7.7% | 8.1 | $1.8B |
| Galena BiopharmaSLS | 27.3% | 55,128,974 | −6.7% | 9.4 | $2.1B |
| Beam TherapeuticsBEAM | 26.7% | 27,548,815 | +6.4% | 15.3 | $2.5B |
| Tango Therapeutics (United States)TNGX | 26.4% | 44,500,110 | +6.3% | 12.5 | $4.0B |
| Neurogene Inc.NGNE | 24.9% | 4,974,749 | +51.7% | 11.7 | $478.1M |
| Replimune Group, Inc.REPL | 24.5% | 23,128,025 | +1.6% | 10.8 | $1.0B |
| Editas MedicineEDIT | 24.2% | 37,109,260 | +23.9% | 9.3 | $360.9M |
| Vera Therapeutics, Inc.VERA | 23.9% | 17,240,397 | +1.2% | 7.8 | $2.1B |
| Altimmune, Inc.ALT | 23.7% | 46,079,911 | −11.0% | 10.5 | $431.8M |
| Inhibrx Biosciences, Inc.INBX | 23.3% | 3,432,642 | +1.1% | 11.8 | $1.3B |
| Monte Rosa TherapeuticsGLUE | 23.1% | 19,686,241 | +2.2% | 18.0 | $906.9M |
| Aquestive Therapeutics, Inc.AQST | 22.9% | 28,748,212 | +5.8% | 13.1 | $471.3M |
| Viking TherapeuticsVKTX | 22.2% | 25,921,759 | +14.8% | 2.2 | $2.9B |
| Xencor IncXNCR | 22.0% | 16,368,875 | +3.9% | 10.1 | $1.7B |
| Absci CorpABSI | 21.8% | 37,442,385 | +0.5% | 7.5 | $1.5B |
| QuidelQDEL | 21.8% | 14,953,442 | +5.4% | 11.0 | $873.7M |
| Sarepta TherapeuticsSRPT | 21.6% | 22,784,187 | −10.4% | 8.6 | $1.9B |
| Annexon, Inc.ANNX | 21.4% | 32,009,914 | −2.6% | 8.9 | $577.9M |
| Relay TherapeuticsRLAY | 21.3% | 46,746,942 | +5.1% | 12.6 | $3.7B |
| Silverback TherapeuticsSPRY | 21.3% | 21,190,047 | −8.2% | 16.1 | $426.1M |
| Avalo Therapeutics, Inc.AVTX | 21.3% | 11,405,304 | −11.8% | 8.8 | $621.0M |
| Savara IncSVRA | 21.2% | 43,563,969 | +0.5% | 17.2 | $965.7M |
| Corvus Pharmaceuticals, Inc.CRVS | 21.2% | 17,797,751 | +3.6% | 13.3 | $808.4M |
| Harrow HealthHROW | 20.7% | 7,762,798 | +3.7% | 12.4 | $1.1B |
| Ultragenyx Pharmaceutical Inc.RARE | 20.6% | 20,349,877 | +22.8% | 3.1 | $1.5B |
| Syndax Pharmaceuticals IncSNDX | 20.4% | 18,234,880 | −11.7% | 8.5 | $1.2B |
Short interest: FINRA equity short interest, reported by broker-dealers twice a month for every exchange-listed and over-the-counter stock. Shares outstanding come from each company’s latest SEC filing; prices from our market snapshot.
Every company
988 biotech and drug companies with a share price or recent SEC financials, largest first. Click a column to sort; type to filter.
| Company | SEC industry | Market value | Past year | Cash | Runway on cash | Short % of shares | Active phase 3 trials | Original NDAs and BLAs |
|---|---|---|---|---|---|---|---|---|
| Eli Lilly and CompanyLLY | Pharmaceutical Preparations | $1.2T | +55.9% | $8.9B | Cash-generating | 0.7% | 93 | 89 |
| Johnson & JohnsonJNJ | Pharmaceutical Preparations | $612.9B | +31.6% | $20.4B | Cash-generating | 0.9% | 81 | 139 |
| AbbVieABBV | Pharmaceutical Preparations | $502.0B | +23.8% | $6.6B | Cash-generating | 0.9% | 71 | 191 |
| Merck & Co.MRK | Pharmaceutical Preparations | $355.1B | +69.8% | $6.8B | Cash-generating | 1.1% | 106 | 178 |
| NovartisNVS | Pharmaceutical or biotech (Wikidata) | $292.1B | +14.5% | $11.4B | Cash-generating | 0.3% | 93 | 167 |
| AstraZenecaAZN | Pharmaceutical Preparations | $261.6B | −2.5% | $5.7B | Cash-generating | 0.2% | 191 | 82 |
| AmgenAMGN | Biological Products, (No Diagnostic Substances) | $231.3B | +43.2% | $14.0B | Cash-generating | 2.6% | 50 | 34 |
| Gilead SciencesGILD | Biological Products, (No Diagnostic Substances) | $191.7B | +25.9% | $3.2B | Cash-generating | 1.8% | 32 | 38 |
| Abbott LaboratoriesABT | Pharmaceutical Preparations | $180.8B | −19.2% | $6.8B | Cash-generating | 0.8% | 0 | 29 |
| NovoNVO | Pharmaceutical Preparations | $173.2B | −29.1% | – | – | 0.7% | 45 | 20 |
| PfizerPFE | Pharmaceutical Preparations | $168.0B | +20.3% | $976.0M | Cash-generating | 2.6% | 94 | 470 |
| Vertex PharmaceuticalsVRTX | Pharmaceutical Preparations | $127.2B | +20.4% | $6.1B | Cash-generating | 1.8% | 17 | 10 |
| Bristol-Myers SquibbBMY | Pharmaceutical Preparations | $120.9B | +35.6% | $8.7B | Cash-generating | 2.2% | 81 | 76 |
| GSKGSK | Pharmaceutical Preparations | $100.3B | +12.9% | – | – | 0.7% | 77 | 140 |
| SanofiSNY | Pharmaceutical Preparations | $98.4B | −21.6% | – | – | 0.4% | 54 | 111 |
| ModernaMRNA | Biological Products, (No Diagnostic Substances) | $90.5B | +771.5% | $1.7B | 14.1 months | 7.7% | 2 | 0 |
| Regeneron PharmaceuticalsREGN | Pharmaceutical Preparations | $82.8B | +35.8% | $2.5B | Cash-generating | 2.0% | 38 | 9 |
| WuXi AppTec2359.HK | Pharmaceutical or biotech (Wikidata) | $75.8B | +85.1% | – | – | – | 0 | 0 |
| Takeda Pharmaceutical CompanyTAK | Pharmaceutical Preparations | $63.7B | +39.8% | – | – | 0.1% | 45 | 63 |
| Argenx SEARGX | Biological Products, (No Diagnostic Substances) | $55.7B | −2.1% | $3.5B | Cash-generating | 2.0% | 17 | 2 |
| Siemens HealthineersSMMNY | Pharmaceutical or biotech (Wikidata) | $52.3B | −18.1% | – | – | 0.0% | 0 | 0 |
| BayerBAYN.F | Pharmaceutical or biotech (Wikidata) | $49.2B | +60.7% | – | – | – | 10 | 99 |
| Teva Pharmaceutical Industries Ltd.TEVA | Pharmaceutical Preparations | $48.2B | +114.3% | $3.7B | Cash-generating | 2.6% | 2 | 109 |
| Jiangsu Hengrui Medicine600276.SS | Pharmaceutical or biotech (Wikidata) | $47.1B | −30.2% | – | – | – | 76 | 0 |
| Sun PharmaceuticalSUNPHARMA.NS | Pharmaceutical or biotech (Wikidata) | $44.1B | +6.0% | – | – | – | 9 | 55 |
| IQVIA Holdings, Inc.IQV | Commercial Physical & Biological Research | $44.1B | +29.2% | $1.9B | Cash-generating | 1.9% | 0 | 0 |
| IDEXX Laboratories, Inc.IDXX | In Vitro & In Vivo Diagnostic Substances | $44.1B | −12.0% | $196.9M | Cash-generating | 2.5% | 0 | 0 |
| BeOne Medicines Ltd.ONC | Pharmaceutical Preparations | $43.9B | +17.5% | $5.1B | Cash-generating | 1.6% | 19 | 7 |
| SandozSDZ.SW | Pharmaceutical or biotech (Wikidata) | $41.1B | +58.2% | – | – | – | 1 | 59 |
| Revolution Medicines (United States)RVMD | Biological Products, (No Diagnostic Substances) | $39.0B | +236.6% | $815.4M | 9.3 months | 5.6% | 0 | 0 |
| Royalty Pharma plcRPRX | Pharmaceutical Preparations | $36.1B | +63.4% | $812.0M | Cash-generating | 2.2% | 0 | 0 |
| BiogenBIIB | Biological Products, (No Diagnostic Substances) | $34.5B | +63.3% | $3.4B | Cash-generating | 4.0% | 17 | 12 |
| ZoetisZTS | Pharmaceutical Preparations | $32.9B | −44.7% | $1.5B | Cash-generating | 4.5% | 0 | 0 |
| Alnylam PharmaceuticalsALNY | Pharmaceutical Preparations | $31.5B | −51.1% | $1.7B | Cash-generating | 5.8% | 5 | 4 |
| Astellas Pharma4503.T | Pharmaceutical or biotech (Wikidata) | $28.2B | +50.0% | – | – | – | 13 | 27 |
| Zai Lab LimitedZLAB | Pharmaceutical Preparations | $26.9B | −15.1% | $607.5M | 72 months | 0.6% | 0 | 0 |
| Hansoh Pharmaceutical Group3692.HK | Pharmaceutical or biotech (Wikidata) | $26.6B | −11.2% | – | – | – | 19 | 0 |
| WuXi Biologics2269.HK | Pharmaceutical or biotech (Wikidata) | $25.9B | +31.5% | – | – | – | 0 | 0 |
| Divi's LaboratoriesDIVISLAB.NS | Pharmaceutical or biotech (Wikidata) | $25.7B | +37.2% | – | – | – | 0 | 0 |
| RoivantROIV | Pharmaceutical Preparations | $25.3B | +102.8% | $1.2B | 18.3 months | 5.4% | 0 | 0 |
| Genmab A/sGMAB | Pharmaceutical Preparations | $24.2B | +16.3% | $1.7B | Cash-generating | 1.0% | 15 | 1 |
| Sartorius Stedim BiotechDIM.PA | Pharmaceutical or biotech (Wikidata) | $23.5B | +4.5% | – | – | – | 0 | 0 |
| UNITED THERAPEUTICS CorpUTHR | Pharmaceutical Preparations | $23.4B | +25.6% | $1.8B | Cash-generating | 8.4% | 3 | 6 |
| BioNTechBNTX | Biological Products, (No Diagnostic Substances) | $23.0B | −15.2% | – | – | 1.0% | 7 | 0 |
| IncyteINCY | Commercial Physical & Biological Research | $22.7B | +29.9% | $3.5B | Cash-generating | 5.0% | 22 | 6 |
| ViatrisVTRS | Pharmaceutical Preparations | $20.9B | +79.2% | $886.5M | Cash-generating | 3.7% | 6 | 74 |
| INSMED IncINSM | Pharmaceutical Preparations | $20.9B | −42.3% | $544.8M | 7.3 months | 6.3% | 5 | 3 |
| StraumannSAUHY | Pharmaceutical or biotech (Wikidata) | $18.7B | +2.3% | – | – | 0.0% | 0 | 0 |
| Torrent PharmaceuticalsTORNTPHARM.NS | Pharmaceutical or biotech (Wikidata) | $18.2B | +29.0% | – | – | – | 0 | 0 |
| MedpaceMEDP | Commercial Physical & Biological Research | $17.4B | +17.9% | $502.7M | Cash-generating | 5.7% | 0 | 0 |
| Shionogi4507.T | Pharmaceutical or biotech (Wikidata) | $16.2B | +21.4% | – | – | – | 2 | 8 |
| Ascendis Pharma A/SASND | Pharmaceutical Preparations | $15.8B | +9.5% | – | – | 5.1% | 2 | 0 |
| ExelixisEXEL | Biological Products, (No Diagnostic Substances) | $15.5B | +59.5% | $281.4M | Cash-generating | 11.4% | 10 | 2 |
| Charles River LaboratoriesCRL | Biological Products, (No Diagnostic Substances) | $14.3B | +67.8% | $192.0M | Cash-generating | 6.0% | 0 | 0 |
| ICON plcICLR | Commercial Physical & Biological Research | $14.3B | −9.3% | $647.3M | Cash-generating | 3.3% | 0 | 0 |
| Yunnan Baiyao Group000538.SZ | Pharmaceutical or biotech (Wikidata) | $14.1B | −8.0% | – | – | – | 0 | 0 |
| Neurocrine BiosciencesNBIX | Biological Products, (No Diagnostic Substances) | $14.0B | −1.9% | $332.4M | Cash-generating | 5.8% | 12 | 4 |
| Halozyme TherapeuticsHALO | Biological Products, (No Diagnostic Substances) | $14.0B | +83.4% | $163.1M | Cash-generating | 13.5% | 1 | 2 |
| Jazz PharmaceuticalsJAZZ | Pharmaceutical Preparations | $13.4B | +52.2% | $1.6B | Cash-generating | 8.4% | 7 | 7 |
| BridgeBioBBIO | Pharmaceutical Preparations | $13.3B | +24.1% | $677.9M | 18.3 months | 10.1% | 0 | 0 |
| CSPC Pharmaceutical Group1093.HK | Pharmaceutical or biotech (Wikidata) | $12.6B | −4.2% | – | – | – | 40 | 1 |
| Summit TherapeuticsSMMT | Pharmaceutical Preparations | $12.6B | −24.9% | $419.4M | 13.1 months | 5.2% | 5 | 0 |
| Corcept TherapeuticsCORT | Pharmaceutical Preparations | $12.1B | +42.8% | $111.0M | Cash-generating | 7.9% | 1 | 2 |
| ElancoELAN | Pharmaceutical Preparations | $11.8B | +10.1% | $530.0M | Cash-generating | 7.5% | 0 | 0 |
| Bio-TechneTECH | Biological Products, (No Diagnostic Substances) | $11.4B | +17.2% | $264.7M | Cash-generating | 4.7% | 0 | 0 |
| CiplaCIPLA.NS | Pharmaceutical or biotech (Wikidata) | $11.2B | −16.1% | – | – | – | 0 | 21 |
| Dr. Reddy's LaboratoriesRDY | Pharmaceutical Preparations | $11.0B | −9.4% | – | – | 3.4% | 0 | 0 |
| BioMarin PharmaceuticalBMRN | Pharmaceutical Preparations | $10.6B | +2.7% | $874.0M | Cash-generating | 6.0% | 6 | 8 |
| Madrigal Pharmaceuticals, INC.MDGL | Pharmaceutical Preparations | $10.3B | +1.4% | $292.7M | 13.1 months | 10.4% | 3 | 1 |
| RepligenRGEN | Biological Products, (No Diagnostic Substances) | $9.9B | +15.4% | $606.8M | Cash-generating | 13.4% | 0 | 0 |
| QiagenQGEN | Biological Products, (No Diagnostic Substances) | $9.9B | −3.1% | $839.0M | Cash-generating | 3.6% | 0 | 0 |
| Vaxcyte, Inc.PCVX | Biological Products, (No Diagnostic Substances) | $9.7B | +53.9% | $183.2M | 2.9 months | 11.6% | 2 | 0 |
| Aurobindo PharmaAUROPHARMA.NS | Pharmaceutical or biotech (Wikidata) | $9.6B | +47.3% | – | – | – | 0 | 15 |
| Krystal Biotech, Inc.KRYS | Biological Products, (No Diagnostic Substances) | $9.5B | +68.5% | $427.7M | Cash-generating | 11.7% | 1 | 0 |
| Lupin Ltd.LUPIN.NS | Pharmaceutical or biotech (Wikidata) | $9.5B | +0.5% | – | – | – | 3 | 13 |
| ImmunityBio, Inc.IBRX | Biological Products, (No Diagnostic Substances) | $9.1B | +256.0% | $75.7M | 3.1 months | 11.7% | 2 | 0 |
| Eisai4523.T | Pharmaceutical or biotech (Wikidata) | $9.0B | +8.7% | – | – | – | 3 | 15 |
| Kymera TherapeuticsKYMR | Biological Products, (No Diagnostic Substances) | $9.0B | +80.5% | $124.5M | 6.2 months | 11.9% | 0 | 0 |
| Twist BioscienceTWST | Biological Products, (No Diagnostic Substances) | $8.8B | +399.6% | $117.4M | 28 months | 16.9% | 0 | 0 |
| CytokineticsCYTK | Pharmaceutical Preparations | $8.7B | +7.4% | $255.3M | 5.8 months | 13.9% | 4 | 1 |
| Protagonist Therapeutics, IncPTGX | Pharmaceutical Preparations | $8.7B | +72.9% | $420.1M | 43 months | 14.4% | 2 | 0 |
| TG TherapeuticsTGTX | Pharmaceutical Preparations | $8.2B | +54.1% | $482.6M | over 10 years | 20.0% | 4 | 1 |
| Abivax S.A.ABVX | Pharmaceutical Preparations | $8.2B | −4.3% | – | – | 8.4% | 1 | 0 |
| Axsome TherapeuticsAXSM | Pharmaceutical Preparations | $8.2B | +21.7% | $319.9M | 54 months | 6.3% | 10 | 2 |
| ALK-AbellóALK-B.CO | Pharmaceutical or biotech (Wikidata) | $8.1B | +12.9% | – | – | – | 0 | 0 |
| Arrowhead PharmaceuticalsARWR | Pharmaceutical Preparations | $8.0B | +54.1% | $54.8M | Cash-generating | 7.6% | 4 | 1 |
| Aeglea BioTherapeuticsSYRE | Pharmaceutical Preparations | $7.5B | +280.8% | $162.0M | 10.5 months | 14.6% | 0 | 0 |
| Ono Pharmaceutical4528.T | Pharmaceutical or biotech (Wikidata) | $7.4B | +34.1% | – | – | – | 8 | 0 |
| Ionis Pharmaceuticals IncIONS | Pharmaceutical Preparations | $7.3B | −39.7% | $350.1M | 4.6 months | 13.5% | 12 | 3 |
| Praxis Precision Medicines, Inc.PRAX | Pharmaceutical Preparations | $7.2B | +36.6% | $474.8M | 20.2 months | 15.0% | 6 | 0 |
| AlkermesALKS | Pharmaceutical Preparations | $7.1B | +40.3% | $511.5M | Cash-generating | 10.6% | 6 | 6 |
| HD Medicine000963.SZ | Pharmaceutical or biotech (Wikidata) | $7.0B | −35.8% | – | – | – | 0 | 0 |
| Lantheus Holdings, Inc.LNTH | In Vitro & In Vivo Diagnostic Substances | $6.5B | +79.9% | $593.3M | Cash-generating | 5.8% | 1 | 7 |
| Pharmaron3759.HK | Pharmaceutical or biotech (Wikidata) | $6.4B | +7.7% | – | – | – | 0 | 0 |
| Alkem LaboratoriesALKEM.NS | Pharmaceutical or biotech (Wikidata) | $6.3B | −10.3% | – | – | – | 0 | 1 |
| Iovance BiotherapeuticsIOVA | Biological Products, (No Diagnostic Substances) | $6.3B | +538.5% | $110.8M | 4.9 months | 14.3% | 1 | 0 |
| Kiniksa Pharmaceuticals International, plcKNSA | Pharmaceutical Preparations | $6.3B | +105.5% | $190.0M | Cash-generating | 4.8% | 1 | 1 |
| Sinopharm Group1099.HK | Pharmaceutical or biotech (Wikidata) | $6.2B | −15.7% | – | – | – | 0 | 0 |
| Belite Bio, IncBLTE | Pharmaceutical Preparations | $6.2B | +65.8% | $352.9M | 115 months | 2.5% | 2 | 0 |
| ActavisACT | Pharmaceutical Preparations | $6.2B | +29.8% | – | – | 2.0% | 0 | 0 |
| Amneal Pharmaceuticals, Inc.AMRX | Pharmaceutical Preparations | $6.2B | +94.6% | $127.6M | Cash-generating | 3.5% | 1 | 13 |
| Rhythm (United states)RYTM | Pharmaceutical Preparations | $6.1B | −20.0% | $65.6M | 6.6 months | 15.6% | 0 | 0 |
| Ligand Pharmaceuticals IncLGND | Pharmaceutical Preparations | $6.0B | +64.7% | $1.0B | Cash-generating | 13.4% | 0 | 1 |
| Kodiak Sciences Inc.KOD | Biological Products, (No Diagnostic Substances) | $5.8B | +556.7% | $125.9M | 10.3 months | 14.9% | 4 | 0 |
| BioconBIOCON.NS | Pharmaceutical or biotech (Wikidata) | $5.8B | −4.5% | – | – | – | 0 | 7 |
| Immunovant, Inc.IMVT | Biological Products, (No Diagnostic Substances) | $5.7B | +56.7% | $797.8M | 23.1 months | 8.4% | 1 | 0 |
| Sumitomo Pharma4506.T | Pharmaceutical or biotech (Wikidata) | $5.5B | +2.9% | – | – | – | 1 | 6 |
| Mirum PharmaceuticalsMIRM | Pharmaceutical Preparations | $5.3B | +11.8% | $330.7M | 23.2 months | 10.8% | 5 | 5 |
| CG Oncology, Inc.CGON | Biological Products, (No Diagnostic Substances) | $5.3B | +43.9% | $19.6M | 1.5 months | 11.8% | 2 | 0 |
| Cogent Biosciences, Inc.COGT | Pharmaceutical Preparations | $5.2B | +82.8% | $181.2M | 7.6 months | 11.2% | 1 | 0 |
| Ipca LaboratoriesIPCALAB.NS | Pharmaceutical or biotech (Wikidata) | $5.1B | +42.2% | – | – | – | 0 | 0 |
| PTC TherapeuticsPTCT | Pharmaceutical Preparations | $5.1B | −6.9% | $1.0B | 58 months | 11.0% | 3 | 3 |
| GrifolsGRFS | Pharmaceutical Preparations | $5.1B | −20.7% | – | – | 1.0% | 4 | 0 |
| Tongrentang600085.SS | Pharmaceutical or biotech (Wikidata) | $5.1B | −29.5% | – | – | – | 0 | 0 |
| Rongchang Pharmacy Co.,Ltd.9995.HK | Pharmaceutical or biotech (Wikidata) | $5.1B | −31.1% | – | – | – | 0 | 0 |
| Veradermics, IncMANE | Pharmaceutical Preparations | $5.1B | – | $319.3M | 48 months | 10.2% | 3 | 0 |
| Oruka Therapeutics, Inc.ORKA | Pharmaceutical Preparations | $5.0B | +174.3% | $268.5M | 35 months | 11.7% | 0 | 0 |
| Scholar Rock Holding CorpSRRK | Biological Products, (No Diagnostic Substances) | $4.9B | +45.4% | $437.1M | 17.3 months | 18.7% | 0 | 0 |
| Baiyunshan600332.SS | Pharmaceutical or biotech (Wikidata) | $4.9B | −22.5% | – | – | – | 0 | 0 |
| Yuhan000100.KS | Pharmaceutical or biotech (Wikidata) | $4.9B | −31.2% | – | – | – | 1 | 0 |
| Amarin CorporationAMRN | Pharmaceutical Preparations | $4.8B | −41.4% | $143.6M | Cash-generating | 0.1% | 0 | 1 |
| CRISPR TherapeuticsCRSP | Biological Products, (No Diagnostic Substances) | $4.8B | −27.8% | $291.3M | 8.7 months | 19.3% | 0 | 0 |
| Travere Therapeutics, Inc.TVTX | Pharmaceutical Preparations | $4.8B | +85.0% | $117.7M | Cash-generating | 13.4% | 2 | 1 |
| Erasca, Inc.ERAS | Pharmaceutical Preparations | $4.7B | +458.7% | $42.5M | 5.6 months | 10.1% | 1 | 0 |
| Structure Therapeutics Inc.GPCR | Pharmaceutical Preparations | $4.7B | −20.0% | $272.6M | 21.1 months | 3.5% | 0 | 0 |
| Hikma PharmaceuticalsHIK.L | Pharmaceutical or biotech (Wikidata) | $4.6B | −6.2% | – | – | – | 0 | 58 |
| Definium TherapeuticsDFTX | Medicinal Chemicals & Botanical Products | $4.4B | +141.9% | $655.3M | 54 months | 8.4% | 4 | 0 |
| Gossamer Bio, Inc.GOSS | Pharmaceutical Preparations | $4.2B | −95.1% | $41.1M | 2.9 months | 0.3% | 1 | 0 |
| Magenta TherapeuticsDNTH | Pharmaceutical Preparations | $4.2B | +109.7% | $110.5M | 10.2 months | 16.3% | 0 | 0 |
| Rohto Pharmaceutical Co., Ltd.4527.T | Pharmaceutical or biotech (Wikidata) | $4.1B | +20.9% | – | – | – | 0 | 0 |
| Edgewise Therapeutics, Inc.EWTX | Pharmaceutical Preparations | $4.1B | +151.3% | $72.3M | 5.8 months | 10.3% | 0 | 0 |
| Arcutis Biotherapeutics, Inc.ARQT | Pharmaceutical Preparations | $4.1B | +55.6% | $34.1M | Cash-generating | 17.3% | 0 | 2 |
| CamurusCAMX.ST | Pharmaceutical or biotech (Wikidata) | $4.0B | −1.9% | – | – | – | 2 | 0 |
| Tango Therapeutics (United States)TNGX | Pharmaceutical Preparations | $4.0B | +162.9% | $345.6M | 29 months | 26.4% | 0 | 0 |
| IndiviorINDV | Pharmaceutical Preparations | $4.0B | +37.3% | $222.0M | 24 months | 8.8% | 0 | 7 |
| Adaptive BiotechnologiesADPT | Biological Products, (No Diagnostic Substances) | $3.8B | +47.3% | $169.9M | 75 months | 7.4% | 0 | 0 |
| Hypera PharmaHYPE3.SA | Pharmaceutical or biotech (Wikidata) | $3.8B | +21.5% | – | – | – | 0 | 0 |
| Relay TherapeuticsRLAY | Biological Products, (No Diagnostic Substances) | $3.7B | +163.1% | $121.2M | 6.8 months | 21.3% | 1 | 0 |
| AbCellera Biologics Inc.ABCL | Pharmaceutical Preparations | $3.7B | +114.5% | $120.1M | 9.4 months | 10.6% | 0 | 0 |
| Legend BiotechLEGN | Pharmaceutical Preparations | $3.6B | −42.2% | $901.9M | 108 months | 8.3% | 0 | 0 |
| Organon & Co.OGN | Pharmaceutical Preparations | $3.6B | +48.1% | $1.1B | Cash-generating | 7.2% | 1 | 57 |
| Simcere Pharmaceutical2096.HK | Pharmaceutical or biotech (Wikidata) | $3.5B | −15.0% | – | – | – | 0 | 0 |
| Telix Pharmaceuticals LimitedTLX | Pharmaceutical Preparations | $3.4B | −0.5% | $141.9M | 98 months | 0.1% | 5 | 2 |
| Xenon PharmaceuticalsXENE | Pharmaceutical Preparations | $3.4B | −15.8% | $119.5M | 4.7 months | 6.2% | 8 | 0 |
| Acadia PharmaceuticalsACAD | Pharmaceutical Preparations | $3.4B | −6.1% | $385.0M | Cash-generating | 4.8% | 3 | 4 |
| Ideaya Biosciences (United States)IDYA | Pharmaceutical Preparations | $3.3B | +15.6% | $272.6M | 38 months | 9.5% | 0 | 0 |
| Parabilis Medicines, Inc.PBLS | Pharmaceutical Preparations | $3.1B | – | $1.1B | – | 6.8% | 0 | 0 |
| Liquidia CorporationLQDA | Pharmaceutical Preparations | $3.1B | +52.7% | $284.2M | Cash-generating | 14.1% | 0 | 0 |
| Tarsus Pharmaceuticals, Inc.TARS | Biological Products, (No Diagnostic Substances) | $3.1B | −4.5% | $204.6M | over 10 years | 13.8% | 0 | 0 |
| Jilin Aodong Medicine000623.SZ | Pharmaceutical or biotech (Wikidata) | $3.0B | −18.3% | – | – | – | 0 | 0 |
| Amylyx PharmaceuticalsAMLX | Pharmaceutical Preparations | $3.0B | +81.0% | $49.3M | 4.9 months | 11.4% | 1 | 1 |
| Disc Medicine, Inc.IRON | Pharmaceutical Preparations | $3.0B | −12.9% | $98.7M | 5.9 months | 18.9% | 1 | 0 |
| Viking TherapeuticsVKTX | Pharmaceutical Preparations | $2.9B | −25.1% | $125.8M | 4.4 months | 22.2% | 4 | 0 |
| Denali Therapeutics Inc.DNLI | Biological Products, (No Diagnostic Substances) | $2.9B | +9.5% | $201.5M | 5.9 months | 9.7% | 2 | 1 |
| Enliven Therapeutics, Inc.ELVN | Pharmaceutical Preparations | $2.8B | +79.0% | $135.5M | 25 months | 14.1% | 0 | 0 |
| Silence TherapeuticsSLN | Pharmaceutical Preparations | $2.8B | +201.2% | $72.1M | 13.2 months | 1.8% | 0 | 0 |
| Maravai LifeSciences Holdings, Inc.MRVI | Pharmaceutical Preparations | $2.8B | +111.2% | $70.1M | 21.3 months | 3.5% | 0 | 0 |
| Arcus BiosciencesRCUS | Pharmaceutical Preparations | $2.8B | +31.5% | $150.0M | 3.7 months | 10.3% | 2 | 0 |
| Nurix (United States)NRIX | Pharmaceutical Preparations | $2.7B | +155.1% | $720.2M | 33 months | 16.2% | 0 | 0 |
| Guangzhou Baiyunshan Pharmaceutical Holdings Company Limited0874.HK | Pharmaceutical or biotech (Wikidata) | $2.7B | −26.6% | – | – | – | 0 | 0 |
| Beta Pharma Inc.300558.SZ | Pharmaceutical or biotech (Wikidata) | $2.7B | −28.6% | – | – | – | 0 | 0 |
| DBV TechnologiesDBVT | Biological Products, (No Diagnostic Substances) | $2.7B | −47.0% | $174.9M | 13.9 months | 0.4% | 3 | 0 |
| Neuland LaboratoriesNEULANDLAB.NS | Pharmaceutical or biotech (Wikidata) | $2.6B | +21.5% | – | – | – | 0 | 0 |
| NeoGenNEOG | In Vitro & In Vivo Diagnostic Substances | $2.5B | +98.4% | $172.0M | Cash-generating | 5.4% | 0 | 0 |
| Hutchison China MeditechHCM | Pharmaceutical Preparations | $2.5B | −6.2% | $71.3M | 13.2 months | 0.2% | 0 | 0 |
| MBX Biosciences, Inc.MBX | Pharmaceutical Preparations | $2.5B | +297.2% | $54.1M | 8.4 months | 9.3% | 1 | 0 |
| ADMA Biologics (United States)ADMA | Biological Products, (No Diagnostic Substances) | $2.5B | −22.8% | $136.0M | Cash-generating | 9.2% | 0 | 0 |
| Beam TherapeuticsBEAM | Biological Products, (No Diagnostic Substances) | $2.5B | −7.6% | $219.8M | 7.1 months | 26.7% | 0 | 0 |
| NewAmsterdam Pharma Co N.V.NAMS | Pharmaceutical Preparations | $2.4B | −44.3% | $424.2M | 36 months | 15.9% | 3 | 0 |
| Bausch HealthBHC | Pharmaceutical Preparations | $2.4B | +4.7% | $1.8B | Cash-generating | 2.2% | 3 | 116 |
| Prestige BrandsPBH | Pharmaceutical Preparations | $2.4B | −19.8% | $89.1M | Cash-generating | 9.8% | 0 | 0 |
| Precigen, IncPGEN | Pharmaceutical Preparations | $2.4B | +64.6% | $16.3M | 1.7 months | 13.3% | 0 | 0 |
| Viridian Therapeutics, Inc.\DEVRDN | Pharmaceutical Preparations | $2.3B | −14.4% | $165.0M | 6.5 months | 15.9% | 3 | 1 |
| Celldex TherapeuticsCLDX | In Vitro & In Vivo Diagnostic Substances | $2.3B | +10.1% | $47.5M | 2.6 months | 14.0% | 4 | 0 |
| Supernus Pharmaceuticals, INC.SUPN | Pharmaceutical Preparations | $2.3B | −20.7% | $180.0M | Cash-generating | 8.6% | 1 | 5 |
| Zealand PharmaZEAL.CO | Pharmaceutical Preparations | $2.3B | −50.9% | – | – | – | 2 | 1 |
| Perrigo Company PlcPRGO | Pharmaceutical Preparations | $2.3B | −24.6% | $399.7M | Cash-generating | 17.5% | 0 | 3 |
| Harmony Biosciences Holdings, Inc.HRMY | Pharmaceutical Preparations | $2.2B | +46.4% | $549.8M | Cash-generating | 9.5% | 0 | 0 |
| Aurinia Pharmaceuticals Inc.AUPH | Pharmaceutical Preparations | $2.2B | +42.9% | $179.7M | Cash-generating | 6.0% | 0 | 1 |
| Pharvaris N.V.PHVS | Pharmaceutical Preparations | $2.2B | +40.5% | – | – | 2.7% | 0 | 0 |
| Galena BiopharmaSLS | Pharmaceutical Preparations | $2.1B | +396.6% | $138.3M | 59 months | 27.3% | 0 | 0 |
| Vera Therapeutics, Inc.VERA | Pharmaceutical Preparations | $2.1B | −7.0% | $48.9M | 2.0 months | 23.9% | 1 | 1 |
| VericelVCEL | Biological Products, (No Diagnostic Substances) | $2.1B | +14.2% | $125.4M | Cash-generating | 10.2% | 2 | 0 |
| Agios PharmaceuticalsAGIO | Pharmaceutical Preparations | $2.1B | −18.8% | $99.6M | 3.1 months | 11.8% | 9 | 1 |
| BioCryst PharmaceuticalsBCRX | Biological Products, (No Diagnostic Substances) | $2.0B | +20.4% | $155.0M | Cash-generating | 10.8% | 2 | 3 |
| CuraleafCURLF | Medicinal Chemicals & Botanical Products | $2.0B | −11.0% | $94.6M | Cash-generating | 0.3% | 0 | 0 |
| Xeris Biopharma Holdings, Inc.XERS | Pharmaceutical Preparations | $2.0B | +19.4% | $121.7M | Cash-generating | 4.0% | 0 | 2 |
| Galápagos NVLKFT | Pharmaceutical Preparations | $2.0B | −13.5% | $40.0M | – | 4.9% | 0 | 0 |
| Trulieve Cannabis Corp.TRLV | Medicinal Chemicals & Botanical Products | $2.0B | +33.9% | $325.4M | Cash-generating | 3.3% | 0 | 0 |
| Recursion PharmaceuticalsRXRX | Biological Products, (No Diagnostic Substances) | $1.9B | −38.0% | $545.7M | 20.4 months | 29.5% | 0 | 0 |
| Immunome Inc.IMNM | Pharmaceutical Preparations | $1.9B | +6.3% | $217.7M | 13.3 months | 14.8% | 1 | 0 |
| ADARx Pharmaceuticals, Inc.ADRX | Pharmaceutical Preparations | $1.9B | – | – | – | 1.1% | 2 | 0 |
| Sarepta TherapeuticsSRPT | Pharmaceutical Preparations | $1.9B | −21.3% | $571.1M | Cash-generating | 21.6% | 4 | 0 |
| Mineralys Therapeutics, Inc.MLYS | Pharmaceutical Preparations | $1.9B | −52.0% | $138.3M | 12.2 months | 8.8% | 1 | 0 |
| AlvotechALVO | Biological Products, (No Diagnostic Substances) | $1.9B | −41.7% | $172.4M | 41 months | 1.7% | 0 | 2 |
| ZymeworksZYME | Pharmaceutical Preparations | $1.8B | +38.9% | $179.4M | 29 months | 7.5% | 0 | 0 |
| Palvella Therapeutics, INC.PVLA | Pharmaceutical Preparations | $1.8B | +69.5% | $187.8M | 77 months | 17.5% | 2 | 0 |
| NovavaxNVAX | Biological Products, (No Diagnostic Substances) | $1.8B | +33.6% | $191.5M | 25 months | 27.9% | 0 | 0 |
| Zenas BioPharma, Inc.ZBIO | Pharmaceutical Preparations | $1.7B | +11.6% | $196.6M | 11.2 months | 18.3% | 4 | 0 |
| VIR BiotechnologyVIR | Biological Products, (No Diagnostic Substances) | $1.7B | +77.1% | $278.7M | 7.5 months | 8.9% | 2 | 0 |
| Braveheart Bio, Inc.BRVE | Pharmaceutical Preparations | $1.7B | – | $122.8M | – | 4.6% | 1 | 0 |
| Xencor IncXNCR | Pharmaceutical Preparations | $1.7B | +56.9% | $44.7M | 2.9 months | 22.0% | 0 | 0 |
| Septerna, Inc.SEPN | Pharmaceutical Preparations | $1.7B | +66.2% | $84.7M | Cash-generating | 6.6% | 0 | 0 |
| Trevi Therapeutics, Inc.TRVI | Pharmaceutical Preparations | $1.7B | +15.1% | $54.3M | 14.4 months | 10.3% | 2 | 0 |
| Biohaven PharmaceuticalsBHVN | Pharmaceutical Preparations | $1.7B | −29.5% | $238.0M | 4.8 months | 12.6% | 7 | 0 |
| Maze Therapeutics, Inc.MAZE | Biological Products, (No Diagnostic Substances) | $1.7B | +9.2% | $202.6M | 20.0 months | 11.8% | 0 | 0 |
| MesoblastMESO | Biological Products, (No Diagnostic Substances) | $1.7B | −29.4% | – | – | 2.4% | 2 | 0 |
| UroGen Pharma Ltd.URGN | Pharmaceutical Preparations | $1.7B | +101.7% | $79.1M | 5.7 months | 15.9% | 3 | 2 |
| Ani Pharmaceuticals IncANIP | Pharmaceutical Preparations | $1.7B | −23.6% | $360.2M | Cash-generating | 15.2% | 0 | 24 |
| LBX Pharmacy603883.SS | Pharmaceutical or biotech (Wikidata) | $1.7B | −14.3% | – | – | – | 0 | 0 |
| Alembic Pharmaceuticals LtdAPLLTD.NS | Pharmaceutical or biotech (Wikidata) | $1.6B | −15.8% | – | – | – | 0 | 1 |
| Generate Biomedicines, Inc.GENB | Pharmaceutical Preparations | $1.6B | – | $135.4M | – | 5.8% | 2 | 0 |
| Stoke Therapeutics, Inc.STOK | Pharmaceutical Preparations | $1.6B | −25.6% | $110.0M | 9.0 months | 17.8% | 1 | 0 |
| Intellia TherapeuticsNTLA | In Vitro & In Vivo Diagnostic Substances | $1.6B | −53.6% | $106.1M | 3.5 months | 32.2% | 3 | 0 |
| Phibro Animal Health CorpPAHC | Pharmaceutical Preparations | $1.6B | −0.9% | $61.4M | Cash-generating | 2.5% | 0 | 0 |
| Nuvation Bio Inc.NUVB | Pharmaceutical Preparations | $1.6B | +30.4% | $258.6M | 25 months | 16.8% | 4 | 0 |
| ImmunocoreIMCR | Biological Products, (No Diagnostic Substances) | $1.5B | −11.2% | $484.9M | over 10 years | 15.3% | 2 | 1 |
| Ascentage Pharma Group InternationalAAPG | Pharmaceutical Preparations | $1.5B | −56.4% | – | – | 0.0% | 7 | 0 |
| Compass PathwaysCMPS | Pharmaceutical Preparations | $1.5B | +68.7% | $433.3M | 33 months | 12.3% | 2 | 0 |
| Innoviva, Inc.INVA | Pharmaceutical Preparations | $1.5B | +22.0% | $570.4M | Cash-generating | 9.5% | 0 | 0 |
| Natco PharmaNATCOPHARM.NS | Pharmaceutical or biotech (Wikidata) | $1.5B | −4.5% | – | – | – | 0 | 0 |
| Kailera Therapeutics, Inc.KLRA | Pharmaceutical Preparations | $1.5B | – | $130.3M | – | 6.7% | 3 | 0 |
| Ultragenyx Pharmaceutical Inc.RARE | Pharmaceutical Preparations | $1.5B | −54.2% | $125.0M | 3.0 months | 20.6% | 9 | 2 |
| Hemab Therapeutics Holdings, Inc.COAG | Biological Products, (No Diagnostic Substances) | $1.5B | – | $237.4M | – | 7.3% | 0 | 0 |
| Absci CorpABSI | Commercial Physical & Biological Research | $1.5B | +88.5% | $107.9M | 13.3 months | 21.8% | 0 | 0 |
| SchrödingerSDGR | Pharmaceutical Preparations | $1.5B | +20.4% | $287.9M | 23.8 months | 16.1% | 0 | 0 |
| Pacira BioSciences, Inc.PCRX | Pharmaceutical Preparations | $1.4B | +59.0% | $205.9M | Cash-generating | 20.3% | 0 | 0 |
| Anaptysbio, IncANAB | Pharmaceutical Preparations | $1.4B | +113.3% | $248.5M | Cash-generating | 18.0% | 0 | 0 |
| Eton Pharmaceuticals, Inc.ETON | Pharmaceutical Preparations | $1.4B | +172.9% | $26.8M | Cash-generating | 6.4% | 0 | 0 |
| uniQure N.V.QURE | Pharmaceutical Preparations | $1.4B | −61.4% | $140.0M | 9.8 months | 13.8% | 0 | 0 |
| North China Pharmaceutical Group Corp600812.SS | Pharmaceutical or biotech (Wikidata) | $1.4B | +4.9% | – | – | – | 0 | 0 |
| Rapport Therapeutics, Inc.RAPP | Pharmaceutical Preparations | $1.4B | +14.7% | $63.6M | 9.5 months | 6.7% | 2 | 0 |
| Ocular Therapeutix, IncOCUL | Pharmaceutical Preparations | $1.4B | −47.2% | $598.6M | 32 months | 13.4% | 4 | 1 |
| Nanobiotix S.A.NBTX | Pharmaceutical Preparations | $1.3B | −16.8% | – | – | 0.2% | 0 | 0 |
| Inhibrx Biosciences, Inc.INBX | Biological Products, (No Diagnostic Substances) | $1.3B | +139.1% | $133.3M | 12.1 months | 23.3% | 1 | 0 |
| GH Research PLCGHRS | Pharmaceutical Preparations | $1.3B | +35.0% | $246.3M | 68 months | 2.5% | 0 | 0 |
| Oric Pharmaceuticals, Inc.ORIC | Pharmaceutical Preparations | $1.3B | −2.1% | $37.5M | 4.1 months | 15.7% | 1 | 0 |
| First Tracks Biotherapeutics, Inc.TRAX | Pharmaceutical Preparations | $1.3B | – | $168.0M | – | 14.5% | 0 | 0 |
| Taysha Gene Therapies, Inc.TSHA | Biological Products, (No Diagnostic Substances) | $1.3B | −16.2% | $455.4M | 49 months | 16.9% | 2 | 0 |
| Lb Pharmaceuticals IncLBRX | Pharmaceutical Preparations | $1.3B | +155.2% | $283.1M | 67 months | 18.6% | 2 | 0 |
| Nektar TherapeuticsNKTR | Pharmaceutical Preparations | $1.2B | −36.9% | $39.3M | 2.3 months | 20.4% | 2 | 0 |
| Kardigan, Inc.KARD | Pharmaceutical Preparations | $1.2B | – | $384.0M | – | 4.8% | 3 | 0 |
| Cronos Group IncCRON | Medicinal Chemicals & Botanical Products | $1.2B | +30.9% | $467.0M | Cash-generating | 0.9% | 0 | 0 |
| Immatics N.V.IMTX | Biological Products, (No Diagnostic Substances) | $1.2B | −27.8% | – | – | 2.2% | 1 | 0 |
| Omeros CorpOMER | Pharmaceutical Preparations | $1.2B | +104.2% | $2.0M | 0.3 months | 15.7% | 0 | 1 |
| Opko Health Inc.OPK | Pharmaceutical Preparations | $1.2B | +5.3% | $300.8M | 22.1 months | 4.8% | 0 | 0 |
| Damora Therapeutics, Inc.DMRA | Pharmaceutical Preparations | $1.2B | +101.5% | $540.5M | over 10 years | 7.7% | 0 | 0 |
| Syndax Pharmaceuticals IncSNDX | Pharmaceutical Preparations | $1.2B | −8.7% | $336.5M | 14.5 months | 20.4% | 1 | 1 |
| Tyra Biosciences, Inc.TYRA | Pharmaceutical Preparations | $1.1B | +32.9% | $73.8M | 8.7 months | 15.8% | 0 | 0 |
| Bicara Therapeutics Inc.BCAX | Pharmaceutical Preparations | $1.1B | −6.1% | $96.6M | 10.0 months | 16.2% | 1 | 0 |
| Amphastar Pharmaceuticals, Inc.AMPH | Pharmaceutical Preparations | $1.1B | +9.3% | $223.6M | Cash-generating | 10.4% | 0 | 4 |
| Vor Biopharma Inc.VOR | Biological Products, (No Diagnostic Substances) | $1.1B | −38.0% | $107.9M | 8.6 months | 13.2% | 2 | 0 |
| Harrow HealthHROW | Pharmaceutical Preparations | $1.1B | −29.7% | $83.9M | Cash-generating | 20.7% | 1 | 0 |
| Avalyn Pharma Inc.AVLN | Pharmaceutical Preparations | $1.0B | – | $264.2M | – | 5.7% | 0 | 0 |
| Replimune Group, Inc.REPL | Biological Products, (No Diagnostic Substances) | $1.0B | +144.2% | $185.4M | 8.0 months | 24.5% | 2 | 0 |
| City Therapeutics, INC.CTY | Pharmaceutical Preparations | $1.0B | – | – | – | – | 0 | 0 |
| KOLON Tissuegene950160.KQ | Pharmaceutical or biotech (Wikidata) | $1.0B | −67.2% | – | – | – | 1 | 0 |
| Janux Therapeutics, Inc.JANX | Pharmaceutical Preparations | $1.0B | −38.0% | $27.8M | 4.3 months | 9.3% | 0 | 0 |
| MannKind CorporationMNKD | Pharmaceutical Preparations | $995.2M | −43.4% | $52.9M | Cash-generating | 8.1% | 0 | 1 |
| Savara IncSVRA | Pharmaceutical Preparations | $965.7M | +30.2% | $41.8M | 4.7 months | 21.2% | 2 | 0 |
| Seaport Therapeutics, Inc.SPTX | Pharmaceutical Preparations | $961.9M | – | $64.2M | – | 6.8% | 0 | 0 |
| Latigo Biotherapeutics, Inc.LTGO | Pharmaceutical Preparations | $950.4M | – | $55.0M | – | 1.3% | 0 | 0 |
| CanSino Biologics6185.HK | Pharmaceutical or biotech (Wikidata) | $947.5M | −34.0% | – | – | – | 4 | 0 |
| Saudi Pharmaceutical Industries and Medical Appliances Corp.2070.SR | Pharmaceutical or biotech (Wikidata) | $914.8M | −2.3% | – | – | – | 0 | 0 |
| Alto Neuroscience, Inc.ANRO | Pharmaceutical Preparations | $907.9M | +280.5% | $243.7M | 47 months | 11.9% | 0 | 0 |
| Monte Rosa TherapeuticsGLUE | Biological Products, (No Diagnostic Substances) | $906.9M | +5.8% | $90.1M | 74 months | 23.1% | 0 | 0 |
| MeiraGTx Holdings plcMGTX | Biological Products, (No Diagnostic Substances) | $899.0M | +20.8% | $143.2M | Cash-generating | 6.2% | 0 | 0 |
| Greenland Mines LtdGRML | Biological Products, (No Diagnostic Substances) | $888.0M | −81.4% | $9.3M | 12.0 months | 0.6% | 0 | 0 |
| Alumis INC.ALMS | Pharmaceutical Preparations | $881.5M | +40.3% | $63.7M | 2.0 months | 7.4% | 1 | 0 |
| Cullinan OncologyCGEM | Biological Products, (No Diagnostic Substances) | $880.4M | +74.2% | $78.6M | 5.3 months | 11.9% | 0 | 0 |
| PeptiDream4587.T | Pharmaceutical or biotech (Wikidata) | $879.5M | −35.1% | – | – | – | 0 | 0 |
| Odyssey Therapeutics, Inc.ODTX | Biological Products, (No Diagnostic Substances) | $878.3M | – | $82.0M | – | 6.5% | 0 | 0 |
| Rigel Pharmaceuticals IncRIGL | Pharmaceutical Preparations | $875.3M | +67.7% | $60.8M | Cash-generating | 15.3% | 1 | 4 |
| QuidelQDEL | In Vitro & In Vivo Diagnostic Substances | $873.7M | −54.7% | $123.4M | Cash-generating | 21.8% | 0 | 0 |
| ArriVent BioPharma, Inc.AVBP | Pharmaceutical Preparations | $872.5M | −9.3% | $154.7M | 13.8 months | 17.1% | 2 | 0 |
| Jade Biosciences, Inc.JBIO | Pharmaceutical Preparations | $862.4M | +44.7% | $107.2M | 12.9 months | 19.1% | 0 | 0 |
| Cryoport, Inc.CYRX | Pharmaceutical Preparations | $862.0M | +68.2% | $269.3M | over 10 years | 4.7% | 0 | 0 |
| Inventiva S.A.IVA | Pharmaceutical Preparations | $858.7M | −38.8% | – | – | 2.9% | 1 | 0 |
| MoonLake ImmunotherapeuticsMLTX | Pharmaceutical Preparations | $827.2M | +6.6% | $477.9M | 26 months | 9.5% | 5 | 0 |
| Arbutus BiopharmaABUS | Pharmaceutical Preparations | $825.0M | −5.4% | $19.2M | 6.7 months | 17.2% | 0 | 0 |
| Kura OncologyKURA | Pharmaceutical Preparations | $819.3M | −6.4% | $70.2M | 10.8 months | 16.2% | 1 | 0 |
| Aktis Oncology, Inc.AKTS | Pharmaceutical Preparations | $812.4M | – | $82.5M | – | 8.8% | 0 | 0 |
| Corvus Pharmaceuticals, Inc.CRVS | Pharmaceutical Preparations | $808.4M | +36.5% | $18.9M | 6.5 months | 21.2% | 1 | 0 |
| Helus Pharma Inc.HELP | Pharmaceutical Preparations | $795.6M | +75.5% | – | – | 4.6% | 0 | 0 |
| Verastem OncologyVSTM | Pharmaceutical Preparations | $794.2M | −4.9% | $136.4M | 10.8 months | 16.5% | 1 | 1 |
| SL Science Holding LtdSLBT | Biological Products, (No Diagnostic Substances) | $779.5M | −85.0% | – | – | 0.0% | 0 | 0 |
| Ardelyx (United States)ARDX | Pharmaceutical Preparations | $772.5M | −38.4% | $97.2M | 32 months | 11.1% | 0 | 0 |
| Geron CorporationGERN | Pharmaceutical Preparations | $767.8M | −0.4% | $62.6M | 6.0 months | 11.5% | 2 | 1 |
| Collegium Pharmaceutical, IncCOLL | Pharmaceutical Preparations | $763.6M | −30.9% | $129.5M | Cash-generating | 16.9% | 0 | 4 |
| Iambic Therapeutics, Inc.IAM | Biological Products, (No Diagnostic Substances) | $749.9M | – | – | – | – | 0 | 0 |
| Adlai Nortye Group Ltd.ANL | Pharmaceutical Preparations | $740.6M | +585.1% | – | – | 6.7% | 0 | 0 |
| Obsidian Therapeutics, Inc.OBX | Pharmaceutical Preparations | $727.1M | – | $0 | – | 1.4% | 0 | 0 |
| Apnimed, Inc.APMD | Pharmaceutical Preparations | $716.9M | – | $172.8M | – | 4.2% | 1 | 0 |
| Lexicon PharmaceuticalsLXRX | Pharmaceutical Preparations | $696.4M | +10.2% | $40.9M | 12.7 months | 5.8% | 1 | 1 |
| Prime Medicine, Inc.PRME | Biological Products, (No Diagnostic Substances) | $692.9M | −29.9% | $47.5M | 3.6 months | 17.7% | 0 | 0 |
| Achieve Life Sciences, INC.ACHV | In Vitro & In Vivo Diagnostic Substances | $686.9M | +58.9% | $48.0M | 12.7 months | 17.0% | 1 | 0 |
| 4D Molecular Therapeutics, Inc.FDMT | Biological Products, (No Diagnostic Substances) | $686.3M | +26.3% | $70.4M | 6.5 months | 20.4% | 3 | 0 |
| Sana BiotechnologySANA | Biological Products, (No Diagnostic Substances) | $685.5M | −54.5% | $57.1M | 5.2 months | 12.9% | 0 | 0 |
| Chemomab Therapeutics Ltd.CMMB | Pharmaceutical Preparations | $684.7M | −64.2% | $7.6M | 8.2 months | 0.0% | 0 | 0 |
| Gyre Therapeutics, INC.GYRE | Pharmaceutical Preparations | $684.7M | −26.0% | $43.3M | Cash-generating | 1.7% | 0 | 0 |
| Pharming Group N.V.PHAR | Pharmaceutical Preparations | $683.0M | −34.0% | $145.3M | Cash-generating | 0.0% | 0 | 0 |
| Design Therapeutics, Inc.DSGN | Pharmaceutical Preparations | $680.3M | +89.4% | $12.9M | 2.9 months | 10.6% | 0 | 0 |
| Chong Kun Dang185750.KS | Pharmaceutical or biotech (Wikidata) | $656.9M | −18.4% | – | – | – | 2 | 0 |
| Aura Investments Ltd.AURA | Biological Products, (No Diagnostic Substances) | $653.3M | +11.1% | $67.8M | 8.9 months | 10.0% | 0 | 0 |
| Ginkgo BioworksDNA | Pharmaceutical or biotech (Wikidata) | $649.2M | −23.1% | $84.5M | 6.1 months | 11.5% | 0 | 0 |
| Attovia Therapeutics, Inc.ATTO | Biological Products, (No Diagnostic Substances) | $648.2M | – | $32.8M | – | 3.6% | 0 | 0 |
| Solid Biosciences Inc.SLDB | Biological Products, (No Diagnostic Substances) | $640.1M | +1.5% | $159.4M | 11.1 months | 11.9% | 1 | 0 |
| Wave Life SciencesWVE | Pharmaceutical Preparations | $625.6M | −59.4% | $368.0M | 24.0 months | 9.4% | 0 | 0 |
| Candel TherapeuticsCADL | Biological Products, (No Diagnostic Substances) | $622.9M | +52.7% | $201.6M | 51 months | 17.0% | 2 | 0 |
| Olema Pharmaceuticals, Inc.OLMA | Pharmaceutical Preparations | $622.1M | −24.0% | $48.6M | 3.9 months | 16.8% | 2 | 0 |
| Avalo Therapeutics, Inc.AVTX | Pharmaceutical Preparations | $621.0M | −24.6% | $85.4M | 17.2 months | 21.3% | 0 | 0 |
| Nuvectis Pharma, Inc.NVCT | Pharmaceutical Preparations | $608.3M | +202.6% | $22.2M | 14.5 months | 7.7% | 0 | 0 |
| Zevra Therapeutics, INC.ZVRA | Pharmaceutical Preparations | $603.9M | −5.9% | $145.3M | Cash-generating | 12.0% | 0 | 1 |
| Immix Biopharma, Inc.IMMX | Pharmaceutical Preparations | $590.9M | +187.8% | $225.5M | 84 months | 14.5% | 0 | 0 |
| Prokidney Corp.PROK | Biological Products, (No Diagnostic Substances) | $588.8M | −52.9% | $74.9M | 6.8 months | 5.7% | 1 | 0 |
| Ironwood PharmaceuticalsIRWD | Pharmaceutical Preparations | $582.5M | +146.5% | $79.1M | Cash-generating | 9.4% | 0 | 2 |
| Annexon, Inc.ANNX | Pharmaceutical Preparations | $577.9M | +22.8% | $199.3M | 13.1 months | 21.4% | 3 | 0 |
| CorMedix Inc.CRMD | Pharmaceutical Preparations | $572.5M | −27.9% | $256.7M | Cash-generating | 19.8% | 1 | 1 |
| Phathom Pharmaceuticals, Inc.PHAT | Pharmaceutical Preparations | $568.3M | −45.8% | $182.5M | 22.5 months | 12.5% | 1 | 4 |
| Electra Therapeutics, Inc.ETRA | Biological Products, (No Diagnostic Substances) | $564.3M | – | – | – | 1.1% | 1 | 0 |
| Climb Bio, Inc.CLYM | Pharmaceutical Preparations | $564.0M | +408.8% | $44.1M | 9.9 months | 16.9% | 0 | 0 |
| EvotecEVO | Pharmaceutical Preparations | $552.6M | −63.5% | – | – | 0.0% | 0 | 0 |
| Sido MunculSIDO.JK | Pharmaceutical or biotech (Wikidata) | $551.2M | −43.3% | – | – | – | 0 | 0 |
| Shattuck Labs, Inc.STTK | Pharmaceutical Preparations | $548.0M | +201.7% | $63.3M | 18.4 months | 10.9% | 0 | 0 |
| Bright Minds Biosciences INC.DRUG | Pharmaceutical Preparations | $533.8M | −16.9% | – | – | 8.7% | 0 | 0 |
| Valneva SEVALN | Biological Products, (No Diagnostic Substances) | $532.0M | −45.6% | – | – | 0.2% | 0 | 0 |
| Puma BiotechnologyPBYI | Pharmaceutical Preparations | $530.7M | +87.9% | $36.5M | Cash-generating | 8.3% | 0 | 0 |
| Medigen Vaccine Biologics6547.TWO | Pharmaceutical or biotech (Wikidata) | $512.4M | +43.0% | – | – | – | 1 | 0 |
| Eupraxia Pharmaceuticals INC.EPRX | Pharmaceutical Preparations | $508.1M | +19.2% | $80.6M | 34 months | 9.2% | 0 | 0 |
| Faeth Therapeutics, Inc.FTH | Pharmaceutical Preparations | $504.3M | +66.8% | $26.9M | 13.4 months | 8.0% | 0 | 0 |
| CytomX Therapeutics, Inc.CTMX | Pharmaceutical Preparations | $501.1M | −28.1% | $17.2M | 2.6 months | 18.7% | 0 | 0 |
| Entera Bio Ltd.ENTX | Biological Products, (No Diagnostic Substances) | $497.8M | +22.3% | $11.3M | 15.0 months | 1.4% | 0 | 0 |
| Aclaris Therapeutics, Inc.ACRS | Pharmaceutical Preparations | $497.5M | +77.9% | $19.2M | 4.4 months | 12.4% | 0 | 1 |
| Oculis Holding AGOCS | Pharmaceutical Preparations | $482.2M | −65.9% | – | – | 2.7% | 0 | 0 |
| Neurogene Inc.NGNE | Pharmaceutical Preparations | $478.1M | −17.7% | $112.5M | 16.4 months | 24.9% | 1 | 0 |
| Evolus, Inc.EOLS | Pharmaceutical Preparations | $477.5M | +13.0% | $45.2M | 14.8 months | 8.5% | 0 | 1 |
| REGENXBIO Inc.RGNX | Biological Products, (No Diagnostic Substances) | $476.3M | −38.5% | $36.5M | 1.9 months | 14.6% | 3 | 0 |
| Monopar TherapeuticsMNPR | Pharmaceutical Preparations | $475.0M | −11.7% | $52.8M | 63 months | 16.2% | 0 | 0 |
| Aquestive Therapeutics, Inc.AQST | Pharmaceutical Preparations | $471.3M | −47.0% | $98.5M | 27 months | 22.9% | 0 | 4 |
| Vireo Growth Inc.VREOF | Pharmaceutical Preparations | $470.3M | −55.7% | $122.7M | Cash-generating | 0.0% | 0 | 0 |
| Arvinas (United States)ARVN | Pharmaceutical Preparations | $469.8M | −24.5% | $94.3M | 4.5 months | 8.2% | 0 | 0 |
| Crescent Biopharma, INC.CBIO | Pharmaceutical Preparations | $463.2M | −0.6% | $171.6M | 30 months | 12.9% | 0 | 0 |
| National Research CorporationNRC | Commercial Physical & Biological Research | $457.4M | +78.1% | $3.3M | Cash-generating | 3.1% | 0 | 0 |
| Kamada Ltd.KMDA | Pharmaceutical Preparations | $451.3M | +13.2% | $75.5M | Cash-generating | 0.4% | 0 | 0 |
| TilrayTLRY | Medicinal Chemicals & Botanical Products | $449.3M | −80.5% | $215.0M | 31 months | 12.7% | 0 | 0 |
| AgomAb Therapeutics NVAGMB | Biological Products, (No Diagnostic Substances) | $448.2M | – | – | – | 1.9% | 0 | 0 |
| Allogene Therapeutics, Inc.ALLO | Biological Products, (No Diagnostic Substances) | $442.9M | +4.2% | $38.6M | 4.2 months | 16.1% | 0 | 0 |
| TRex Bio, Inc.TRXB | Biological Products, (No Diagnostic Substances) | $442.7M | – | – | – | – | 0 | 0 |
| Prothena Corp Public Ltd CoPRTA | Pharmaceutical Preparations | $434.3M | −14.7% | $288.2M | 43 months | 15.6% | 0 | 0 |
| Eikon Therapeutics, Inc.EIKN | Biological Products, (No Diagnostic Substances) | $434.1M | – | $142.6M | – | 11.6% | 2 | 0 |
| BlossomHill Therapeutics, Inc.BLSM | Pharmaceutical Preparations | $432.9M | – | $95.4M | – | 1.5% | 0 | 0 |
| Altimmune, Inc.ALT | Pharmaceutical Preparations | $431.8M | −42.0% | $63.0M | 10.6 months | 23.7% | 1 | 0 |
| DiaMedica Therapeutics Inc.DMAC | Pharmaceutical Preparations | $429.2M | +21.0% | $5.1M | 2.0 months | 10.3% | 1 | 0 |
| Ovid Therapeutics Inc.OVID | Pharmaceutical Preparations | $428.7M | +48.3% | $11.3M | 3.2 months | 9.7% | 0 | 0 |
| Silverback TherapeuticsSPRY | Pharmaceutical Preparations | $426.1M | −57.4% | $8.2M | 0.6 months | 21.3% | 0 | 0 |
| Autolus TherapeuticsAUTL | Biological Products, (No Diagnostic Substances) | $418.1M | −3.0% | $171.4M | 7.5 months | 3.2% | 0 | 0 |
| Tectonic Therapeutic, Inc.TECX | Biological Products, (No Diagnostic Substances) | $414.4M | +22.8% | $227.1M | 42 months | 11.4% | 0 | 0 |
| Assembly Biosciences, INC.ASMB | Pharmaceutical Preparations | $409.5M | −31.7% | $32.3M | 9.7 months | 13.9% | 0 | 0 |
| Kyorin Pharmaceutical4569.T | Pharmaceutical or biotech (Wikidata) | $405.5M | −22.5% | – | – | – | 0 | 0 |
| Myriad GeneticsMYGN | In Vitro & In Vivo Diagnostic Substances | $397.4M | −46.7% | $115.2M | Cash-generating | 8.9% | 0 | 0 |
| Capricor Therapeutics, INC.CAPR | Pharmaceutical Preparations | $385.8M | +6.2% | $20.9M | 2.7 months | 32.4% | 1 | 0 |
| Scribe Therapeutics, Inc.SCTX | Biological Products, (No Diagnostic Substances) | $371.5M | – | $35.6M | – | 13.0% | 0 | 0 |
| Indaptus Therapeutics, Inc.INDP | Pharmaceutical Preparations | $370.4M | −24.9% | $7.6M | 5.4 months | 0.6% | 0 | 0 |
| CytoDyn Inc.CYDY | Pharmaceutical Preparations | $368.6M | −7.1% | $16.4M | 8.7 months | 2.5% | 0 | 0 |
| Zura Bio LtdZURA | Biological Products, (No Diagnostic Substances) | $365.6M | +18.9% | $205.1M | 34 months | 9.8% | 0 | 0 |
| Alpha Teknova, Inc.TKNO | In Vitro & In Vivo Diagnostic Substances | $364.8M | +32.5% | $6.0M | 9.1 months | 3.0% | 0 | 0 |
| Aska Pharmaceutical4886.T | Pharmaceutical or biotech (Wikidata) | $363.4M | −3.3% | – | – | – | 0 | 0 |
| Fennec Pharmaceuticals INC.FENC | Biological Products, (No Diagnostic Substances) | $362.1M | +25.3% | $41.2M | 86 months | 1.5% | 0 | 1 |
| MapLight Therapeutics, Inc.MPLT | Pharmaceutical Preparations | $361.5M | – | $71.6M | 5.2 months | 6.9% | 0 | 0 |
| Editas MedicineEDIT | Biological Products, (No Diagnostic Substances) | $360.9M | −37.7% | $181.8M | 15.5 months | 24.2% | 0 | 0 |
| Kyverna Therapeutics, Inc.KYTX | Biological Products, (No Diagnostic Substances) | $359.0M | −12.4% | $31.8M | 2.5 months | 15.6% | 1 | 0 |
| Rezolute, Inc.RZLT | Pharmaceutical Preparations | $357.4M | −57.5% | $10.6M | 2.0 months | 17.3% | 0 | 0 |
| Galectin Therapeutics IncGALT | Pharmaceutical Preparations | $356.5M | −29.2% | $13.3M | 7.9 months | 9.1% | 0 | 0 |
| C4 Therapeutics (United States)CCCC | Biological Products, (No Diagnostic Substances) | $354.9M | +21.7% | $78.6M | 9.9 months | 32.8% | 0 | 0 |
| Atea Pharmaceuticals, Inc.AVIR | Pharmaceutical Preparations | $345.7M | +40.9% | $76.5M | 6.2 months | 9.8% | 2 | 0 |
| Prenetics Global LtdPRE | Pharmaceutical Preparations | $342.2M | +27.9% | – | – | 2.5% | 0 | 0 |
| Enanta Pharmaceuticals IncENTA | Pharmaceutical Preparations | $337.9M | +5.4% | $33.4M | 28 months | 8.8% | 0 | 0 |
| Relmada Therapeutics, INC.RLMD | Pharmaceutical Preparations | $337.6M | +57.5% | $11.3M | 3.2 months | 12.6% | 1 | 0 |
| Emergent BioSolutionsEBS | Pharmaceutical Preparations | $331.5M | −29.4% | $139.7M | Cash-generating | 18.1% | 0 | 0 |
| Turn Therapeutics Inc.TTRX | Pharmaceutical Preparations | $319.9M | +112.2% | $9.9M | 31 months | 0.9% | 1 | 0 |
| SNDL Inc.SNDL | Medicinal Chemicals & Botanical Products | $318.7M | −45.9% | – | – | 0.7% | 0 | 0 |
| Impact Biomedical INC.IBO | Pharmaceutical Preparations | $318.1M | −60.9% | $20.0K | 0.1 months | 0.0% | 0 | 0 |
| Opus Genetics, Inc.IRD | Pharmaceutical Preparations | $314.9M | +102.4% | $88.8M | 27 months | 15.6% | 1 | 0 |
| GT Biopharma, Inc.GTBP | Pharmaceutical Preparations | $307.9M | +887.7% | $5.0M | 4.5 months | 0.6% | 0 | 0 |
| Fuji Pharma4554.T | Pharmaceutical or biotech (Wikidata) | $306.3M | +15.3% | – | – | – | 0 | 0 |
| Canopy Growth CorporationCGC | Medicinal Chemicals & Botanical Products | $300.3M | −45.8% | – | – | 6.4% | 0 | 0 |
| Benitec Biopharma LtdBNTC | Pharmaceutical Preparations | $296.7M | −45.6% | $180.0M | over 10 years | 5.8% | 0 | 0 |
| Arcturus TherapeuticsARCT | Pharmaceutical Preparations | $294.7M | −49.8% | $191.5M | 39 months | 18.9% | 0 | 0 |
| Artiva Biotherapeutics, Inc.ARTV | Biological Products, (No Diagnostic Substances) | $288.0M | −2.0% | $301.5M | 46 months | 4.7% | 0 | 0 |
| Surrozen, Inc./DESRZN | Biological Products, (No Diagnostic Substances) | $285.0M | +78.6% | $102.0M | 37 months | 18.6% | 0 | 0 |
| Quoin Pharmaceuticals Ltd.QNRX | Pharmaceutical Preparations | $284.7M | −72.8% | $3.8M | 2.9 months | 0.1% | 4 | 0 |
| Fulcrum Therapeutics (United States)FULC | Pharmaceutical Preparations | $282.3M | −58.8% | $48.5M | 9.2 months | 9.3% | 0 | 0 |
| AgenusAGEN | Biological Products, (No Diagnostic Substances) | $278.5M | +59.4% | $18.7M | 2.6 months | 15.1% | 0 | 0 |
| USANA Health SciencesUSNA | Medicinal Chemicals & Botanical Products | $274.7M | −28.8% | $168.6M | Cash-generating | 4.2% | 0 | 0 |
| OneMedNet CorpONMD | Commercial Physical & Biological Research | $273.3M | −79.8% | $358.0K | 0.6 months | 0.2% | 0 | 0 |
| X4 Pharmaceuticals, IncXFOR | Biological Products, (No Diagnostic Substances) | $273.1M | −7.2% | $195.1M | 25 months | 7.7% | 1 | 1 |
| OcugenOCGN | Biological Products, (No Diagnostic Substances) | $272.2M | −49.8% | $100.1M | 20.2 months | 30.1% | 3 | 0 |
| Cypherpunk Technologies INC.CYPH | Pharmaceutical Preparations | $271.0M | +355.6% | $7.6M | 2.8 months | 12.5% | 0 | 0 |
| Sagimet Biosciences Inc.SGMT | Pharmaceutical Preparations | $270.7M | +19.9% | $165.9M | 50 months | 36.5% | 1 | 0 |
| Prelude Therapeutics IncPRLD | Pharmaceutical Preparations | $268.9M | +183.2% | $26.3M | 7.2 months | 5.7% | 0 | 0 |
| Elite Pharmaceuticals Inc /nv/ELTP | Pharmaceutical Preparations | $267.2M | −60.0% | $39.4M | Cash-generating | 0.2% | 0 | 0 |
| Century Therapeutics (United States)IPSC | Biological Products, (No Diagnostic Substances) | $267.1M | +172.1% | $49.6M | 6.3 months | 16.1% | 0 | 0 |
| Northwest BiotherapeuticsNWBO | Pharmaceutical Preparations | $264.4M | −32.6% | $595.0K | 0.1 months | 4.5% | 0 | 0 |
| Vicore Pharma Holding ABVCRE | Pharmaceutical Preparations | $258.8M | – | – | – | 0.0% | 0 | 0 |
| Aurora CannabisACB | Medicinal Chemicals & Botanical Products | $257.4M | −23.9% | – | – | 11.9% | 0 | 0 |
| Abeona Therapeutics INC.ABEO | Pharmaceutical Preparations | $253.9M | −17.5% | $56.2M | 8.7 months | 29.5% | 1 | 0 |
| Bicycle Therapeutics (United Kingdom)BCYC | Pharmaceutical Preparations | $253.4M | −55.6% | $510.1M | 27 months | 4.7% | 0 | 0 |
| Pharmaniaga7081.KL | Pharmaceutical or biotech (Wikidata) | $252.3M | −40.0% | – | – | – | 0 | 0 |
| Standard BioTools Inc.LAB | Pharmaceutical Preparations | $250.9M | −49.7% | $270.0M | 36 months | 0.6% | 0 | 0 |
| Kwang Dong Pharmaceutical009290.KS | Pharmaceutical or biotech (Wikidata) | $249.3M | +20.9% | – | – | – | 0 | 0 |
| Rocket Pharmaceuticals Inc.RCKT | Pharmaceutical Preparations | $247.5M | −39.2% | $224.5M | 15.0 months | 13.7% | 0 | 0 |
| Vanda Pharmaceuticals Inc.VNDA | Pharmaceutical Preparations | $247.0M | −22.5% | $55.9M | 5.3 months | 13.0% | 9 | 6 |
| Cabaletta Bio, Inc.CABA | Biological Products, (No Diagnostic Substances) | $246.7M | −49.0% | $225.1M | 18.9 months | 22.8% | 2 | 0 |
| AC Immune SAACIU | Pharmaceutical Preparations | $246.6M | −16.7% | – | – | 3.5% | 0 | 0 |
| Mereo BioPharma Group plcMREO | Pharmaceutical Preparations | $246.2M | −85.0% | $30.1M | 13.4 months | 0.3% | 0 | 0 |
| Perspective Therapeutics, Inc.CATX | Pharmaceutical Preparations | $246.0M | −52.0% | $48.5M | 6.3 months | 14.5% | 0 | 0 |
| Immuneering CorpIMRX | Pharmaceutical Preparations | $244.2M | −35.0% | $41.3M | 10.0 months | 23.0% | 1 | 0 |
| Lifecore Biomedical, INC. \de\LFCR | Pharmaceutical Preparations | $242.6M | −1.2% | $17.2M | over 10 years | 6.5% | 0 | 0 |
| Cresco Labs Inc.CRLBF | Medicinal Chemicals & Botanical Products | $240.7M | −50.8% | $57.9M | Cash-generating | 0.3% | 0 | 0 |
| Lineage Cell TherapeuticsLCTX | Biological Products, (No Diagnostic Substances) | $239.7M | −42.5% | $37.4M | 20.3 months | 11.5% | 0 | 0 |
| Vogenx, Inc.VOGX | Pharmaceutical Preparations | $237.8M | – | $193.0K | – | 0.2% | 0 | 0 |
| SAB Biotherapeutics, Inc.SABS | Biological Products, (No Diagnostic Substances) | $237.0M | +3.8% | $8.3M | 1.9 months | 4.7% | 0 | 0 |
| Palisade Bio, INC.PALI | Biological Products, (No Diagnostic Substances) | $232.7M | −23.3% | $125.2M | over 10 years | 17.8% | 0 | 0 |
| Q32 Bio Inc.QTTB | Pharmaceutical Preparations | $232.5M | +146.4% | $106.3M | 47 months | 15.7% | 0 | 0 |
| InflaRx N.V.IFRX | Pharmaceutical Preparations | $230.6M | +23.3% | – | – | 7.8% | 0 | 0 |
| BioAge Labs, Inc.BIOA | Pharmaceutical Preparations | $227.0M | −4.5% | $74.0M | 10.1 months | 7.1% | 0 | 0 |
| Siga Technologies IncSIGA | Pharmaceutical Preparations | $226.7M | −62.0% | $117.6M | Cash-generating | 5.0% | 0 | 2 |
| Fate TherapeuticsFATE | Biological Products, (No Diagnostic Substances) | $225.3M | +27.9% | $32.4M | 3.8 months | 9.0% | 0 | 0 |
| BridgeBio Oncology Therapeutics, Inc.BBOT | Pharmaceutical Preparations | $224.9M | −74.8% | $54.1M | 5.0 months | 4.2% | 0 | 0 |
| Lexeo Therapeutics, Inc.LXEO | Biological Products, (No Diagnostic Substances) | $221.5M | −71.8% | $92.8M | 11.4 months | 23.5% | 0 | 0 |
| Greenwich LifeSciences, Inc.GLSI | Pharmaceutical Preparations | $220.8M | +58.5% | $8.9M | 8.3 months | 10.8% | 1 | 0 |
| Nature's Sunshine ProductsNATR | Pharmaceutical Preparations | $220.8M | −11.5% | $82.5M | Cash-generating | 4.9% | 0 | 0 |
| Glass House Brands Inc.GLAS | Medicinal Chemicals & Botanical Products | $220.5M | −72.2% | $23.4M | Cash-generating | 0.4% | 0 | 0 |
| Sol-Gel Technologies Ltd.SLGL | Pharmaceutical Preparations | $220.0M | +60.1% | $11.0M | Cash-generating | 4.3% | 0 | 0 |
| Inhibikase Therapeutics, Inc.IKT | Biological Products, (No Diagnostic Substances) | $219.8M | +0.3% | $31.2M | 10.5 months | 13.9% | 2 | 0 |
| Zafgen (United States)LRMR | Pharmaceutical Preparations | $219.2M | −49.8% | $92.7M | 8.5 months | 14.8% | 0 | 0 |
| Keros Therapeutics, Inc.KROS | Pharmaceutical Preparations | $218.9M | −20.2% | $257.6M | 54 months | 5.8% | 0 | 0 |
| Panacea BiotecPANACEABIO.NS | Pharmaceutical or biotech (Wikidata) | $218.6M | −20.2% | – | – | – | 0 | 0 |
| OBI Pharma, Inc.4174.TWO | Pharmaceutical or biotech (Wikidata) | $216.8M | +6.5% | – | – | – | 1 | 0 |
| Alector (United States)ALEC | Biological Products, (No Diagnostic Substances) | $216.1M | −36.4% | $59.9M | 4.2 months | 5.5% | 0 | 0 |
| Lyell Immunopharma, Inc.LYEL | Pharmaceutical Preparations | $214.9M | −46.9% | $73.0M | 6.5 months | 5.2% | 1 | 0 |
| Liminatus Pharma, Inc.LIMN | Biological Products, (No Diagnostic Substances) | $213.6M | −94.5% | – | – | 0.1% | 0 | 0 |
| Macrogenics IncMGNX | Pharmaceutical Preparations | $212.4M | +102.1% | $113.9M | 19.5 months | 11.1% | 0 | 0 |
| Protalix Biotherapeutics IncPLX | Biological Products, (No Diagnostic Substances) | $205.0M | +36.8% | $27.4M | Cash-generating | 3.8% | 0 | 0 |
| Compugen Ltd.CGEN | Biological Products, (No Diagnostic Substances) | $203.2M | +5.8% | $90.6M | Cash-generating | 2.3% | 0 | 0 |
| Camp4 Therapeutics CorpCAMP | Pharmaceutical Preparations | $199.6M | +8.5% | $86.4M | 39 months | 2.3% | 0 | 0 |
| Niagen Bioscience, Inc.NAGE | Medicinal Chemicals & Botanical Products | $197.8M | −65.9% | $66.7M | Cash-generating | 4.9% | 0 | 0 |
| ProQR Therapeutics N.V.PRQR | Pharmaceutical Preparations | $196.9M | −52.0% | – | – | 1.9% | 1 | 0 |
| Akebia Therapeutics, Inc.AKBA | Pharmaceutical Preparations | $192.5M | −76.3% | $155.5M | Cash-generating | 8.1% | 0 | 1 |
| Evommune, Inc.EVMN | Pharmaceutical Preparations | $191.5M | – | $60.0M | 9.0 months | 8.0% | 0 | 0 |
| ADC Therapeutics SAADCT | Pharmaceutical Preparations | $188.3M | −63.9% | $219.1M | 23.0 months | 5.4% | 1 | 1 |
| Sutro BiopharmaSTRO | Biological Products, (No Diagnostic Substances) | $187.8M | +12.1% | $54.3M | 4.3 months | 11.1% | 0 | 0 |
| Entrada Therapeutics, Inc.TRDA | Pharmaceutical Preparations | $187.3M | −18.1% | $99.3M | 9.0 months | 7.7% | 0 | 0 |
| Sionna Therapeutics, Inc.SION | Pharmaceutical Preparations | $184.0M | −87.2% | $63.3M | 10.6 months | 8.4% | 0 | 0 |
| Selecta Biosciences (United States)RNAC | Pharmaceutical Preparations | $184.0M | −32.5% | $147.6M | 24 months | 6.1% | 0 | 0 |
| PepGen Inc.PEPG | Pharmaceutical Preparations | $183.9M | −45.7% | $22.8M | 3.5 months | 6.1% | 0 | 0 |
| Alpha Cognition Inc.ACOG | Biological Products, (No Diagnostic Substances) | $183.5M | +23.9% | $41.4M | 16.5 months | 1.5% | 0 | 1 |
| Invivyd, Inc.IVVD | Biological Products, (No Diagnostic Substances) | $182.9M | −64.3% | $160.1M | 24 months | 11.5% | 1 | 0 |
| Eledon Pharmaceuticals, Inc.ELDN | Pharmaceutical Preparations | $179.2M | −35.9% | $6.8M | 1.2 months | 9.7% | 1 | 0 |
| Whitehawk Therapeutics, Inc.WHWK | Pharmaceutical Preparations | $174.7M | +38.7% | $85.2M | 9.5 months | 4.8% | 0 | 0 |
| Medicus Pharma Ltd.MDCX | Pharmaceutical Preparations | $170.6M | −97.7% | $15.2M | 6.5 months | 5.8% | 0 | 0 |
| Oramed PharmaceuticalsORMP | Pharmaceutical Preparations | $169.7M | +82.9% | $15.2M | 21.4 months | 3.4% | 1 | 0 |
| Precision BioSciencesDTIL | Biological Products, (No Diagnostic Substances) | $169.1M | −11.2% | $86.1M | 17.6 months | 9.1% | 0 | 0 |
| Adagene Inc.ADAG | Pharmaceutical Preparations | $168.5M | +24.4% | $74.5M | 57 months | 2.7% | 0 | 0 |
| Zentalis Pharmaceuticals, Inc.ZNTL | Pharmaceutical Preparations | $164.1M | +53.7% | $24.8M | 2.4 months | 8.3% | 0 | 0 |
| Nervgen Pharma Corp.NGEN | Pharmaceutical Preparations | $163.4M | −46.1% | – | – | 5.6% | 1 | 0 |
| NovaBridge BiosciencesNBP | Pharmaceutical Preparations | $159.5M | −77.1% | $210.6M | – | 2.7% | 0 | 0 |
| Contineum Therapeutics, Inc.CTNM | Pharmaceutical Preparations | $159.3M | −41.1% | $14.7M | 3.1 months | 13.3% | 0 | 0 |
| MediWound Ltd.MDWD | Medicinal Chemicals & Botanical Products | $158.8M | −34.2% | $4.8M | 3.6 months | 14.4% | 1 | 1 |
| Anbio BiotechnologyNNNN | In Vitro & In Vivo Diagnostic Substances | $158.0M | −88.1% | $7.8M | 13.8 months | 0.1% | 0 | 0 |
| Veraxa Biotech AG - Post de-SPACVRXA | Pharmaceutical Preparations | $157.0M | −90.4% | – | – | 0.2% | 0 | 0 |
| Upstream Bio, Inc.UPB | Pharmaceutical Preparations | $153.9M | −86.6% | $79.4M | 6.8 months | 8.2% | 0 | 0 |
| Korsana Biosciences, Inc.KRSA | Pharmaceutical Preparations | $152.2M | +107.3% | $1.4M | 4.7 months | 0.2% | 0 | 0 |
| Coherus BioSciences (United States)CHRS | Biological Products, (No Diagnostic Substances) | $151.7M | −40.5% | $82.9M | 5.8 months | 15.1% | 0 | 0 |
| Compass Therapeutics, Inc.CMPX | Biological Products, (No Diagnostic Substances) | $151.3M | −80.3% | $35.5M | 8.0 months | 22.4% | 1 | 0 |
| Curanex Pharmaceuticals IncCURX | Pharmaceutical Preparations | $150.6M | −60.7% | $2.9M | 3.1 months | 0.0% | 0 | 0 |
| Alx Oncology Holdings IncALXO | Pharmaceutical Preparations | $149.3M | −28.0% | $22.7M | 3.5 months | 4.1% | 0 | 0 |
| Pyxis Oncology, Inc.PYXS | Pharmaceutical Preparations | $146.0M | −47.9% | $18.9M | 3.4 months | 5.9% | 0 | 0 |
| Satellos Bioscience Inc.MSLE | Pharmaceutical Preparations | $145.1M | −7.3% | $9.8M | 5.0 months | 0.5% | 0 | 0 |
| Cardiol Therapeutics Inc.CRDL | Biological Products, (No Diagnostic Substances) | $144.2M | +4.8% | – | – | 2.3% | 1 | 0 |
| Proteon TherapeuticsTARA | Biological Products, (No Diagnostic Substances) | $140.6M | −56.6% | $17.1M | 3.3 months | 9.8% | 0 | 0 |
| Organigram Global INC.OGI | Pharmaceutical Preparations | $135.5M | −48.0% | – | – | 3.1% | 0 | 0 |
| MaxCyte (United States)MXCT | Commercial Physical & Biological Research | $134.2M | −19.2% | $15.0M | 6.4 months | 1.1% | 0 | 0 |
| Retension Pharmaceuticals, Inc.RTSN | Pharmaceutical Preparations | $133.5M | – | – | – | – | 0 | 0 |
| KOLON Life Science102940.KQ | Pharmaceutical or biotech (Wikidata) | $132.8M | −57.9% | – | – | – | 0 | 0 |
| Atrium Therapeutics, Inc.RNA | Pharmaceutical Preparations | $132.1M | – | $72.3M | – | 19.9% | 0 | 0 |
| Tiziana Life Sciences LtdTLSA | Pharmaceutical Preparations | $129.2M | −48.2% | – | – | 2.1% | 0 | 0 |
| Nkarta Therapeutics (United States)NKTX | Pharmaceutical Preparations | $127.9M | −22.4% | $25.0M | 3.4 months | 5.1% | 0 | 0 |
| Korro Bio, Inc.KRRO | Pharmaceutical Preparations | $126.9M | −79.5% | $24.9M | 4.3 months | 11.4% | 0 | 0 |
| Organogenesis Holdings Inc.ORGO | Pharmaceutical Preparations | $126.7M | −75.6% | $46.1M | Cash-generating | 11.7% | 0 | 0 |
| Voyager Therapeutics (United States)VYGR | Biological Products, (No Diagnostic Substances) | $126.6M | −58.5% | $35.8M | 3.4 months | 6.4% | 0 | 0 |
| Acumen Pharmaceuticals, Inc.ABOS | Biological Products, (No Diagnostic Substances) | $126.6M | −13.8% | $59.4M | 6.8 months | 4.3% | 0 | 0 |
| Outlook Therapeutics, Inc.OTLK | Biological Products, (No Diagnostic Substances) | $123.7M | −61.2% | $11.2M | 2.4 months | 13.1% | 1 | 1 |
| AN2 Therapeutics, Inc.ANTX | Pharmaceutical Preparations | $123.4M | +174.8% | $44.3M | 17.0 months | 6.6% | 0 | 0 |
| Cue Biopharma, Inc.CUE | Pharmaceutical Preparations | $122.1M | −29.6% | $17.4M | 8.5 months | 9.7% | 0 | 0 |
| Armata Pharmaceuticals, Inc.ARMP | Biological Products, (No Diagnostic Substances) | $120.8M | −4.4% | $24.0M | 12.0 months | 2.6% | 0 | 0 |
| Semnur Pharmaceuticals, Inc.SMNR | Pharmaceutical Preparations | $119.7M | −94.2% | $39.0K | 0.1 months | 0.0% | 1 | 0 |
| Scienture Holdings, Inc.SCNX | Pharmaceutical Preparations | $119.1M | −78.3% | $8.2M | 7.4 months | 3.2% | 0 | 2 |
| VaxartVXRT | Biological Products, (No Diagnostic Substances) | $116.8M | +33.6% | $50.9M | Cash-generating | 1.0% | 0 | 0 |
| NRX Pharmaceuticals, Inc.NRXP | Pharmaceutical Preparations | $116.2M | −15.6% | $26.7M | 21.5 months | 22.6% | 0 | 0 |
| Spruce Biosciences, INC.SPRB | Pharmaceutical Preparations | $115.3M | −74.6% | $96.3M | 39 months | 15.0% | 1 | 0 |
| TuHURA Biosciences, Inc./NVHURA | Pharmaceutical Preparations | $112.5M | −26.5% | $996.0K | 0.4 months | 9.6% | 1 | 0 |
| Humacyte, Inc.HUMA | Biological Products, (No Diagnostic Substances) | $112.3M | −76.5% | $79.9M | 9.4 months | 10.6% | 2 | 0 |
| GENELUX CorpGNLX | Pharmaceutical Preparations | $111.5M | −56.9% | $9.2M | 4.3 months | 9.6% | 0 | 0 |
| vTv Therapeutics Inc.VTVT | Pharmaceutical Preparations | $111.5M | +33.2% | $86.6M | 100 months | 3.8% | 1 | 0 |
| Foghorn Therapeutics Inc.FHTX | Pharmaceutical Preparations | $111.3M | −53.0% | $68.1M | 9.3 months | 3.6% | 0 | 0 |
| enGene Therapeutics Inc.ENGN | Biological Products, (No Diagnostic Substances) | $109.9M | −82.5% | $41.0M | 4.8 months | 2.1% | 0 | 0 |
| Minerva Neurosciences (United States)NERV | Pharmaceutical Preparations | $109.3M | −8.1% | $24.7M | 19.9 months | 5.1% | 0 | 0 |
| Anavex Life Sciences Corp.AVXL | Biological Products, (No Diagnostic Substances) | $108.0M | −87.0% | $118.3M | 42 months | 14.6% | 0 | 0 |
| Black Diamond Therapeutics, Inc.BDTX | Biological Products, (No Diagnostic Substances) | $104.3M | −54.7% | $19.2M | 6.8 months | 8.3% | 0 | 0 |
| Inovio PharmaceuticalsINO | Pharmaceutical Preparations | $103.4M | −57.5% | $31.5M | 4.5 months | 20.1% | 0 | 0 |
| LENZ Therapeutics, Inc.LENZ | Biological Products, (No Diagnostic Substances) | $102.0M | −91.5% | $24.2M | 3.4 months | 33.6% | 0 | 1 |
| Jushi Holdings Inc.JUSH | Medicinal Chemicals & Botanical Products | $101.8M | −32.0% | $33.3M | Cash-generating | 0.4% | 0 | 0 |
| Coya Therapeutics, Inc.COYA | Pharmaceutical Preparations | $100.4M | −32.7% | $43.2M | 37 months | 5.1% | 1 | 0 |
| Tonix PharmaceuticalsTNXP | Pharmaceutical Preparations | $98.3M | −69.2% | $176.2M | 16.8 months | 17.1% | 0 | 1 |
| Unicycive Therapeutics, Inc.UNCY | Pharmaceutical Preparations | $98.2M | −25.2% | $44.2M | 18.5 months | 17.4% | 0 | 0 |
| Cumberland Pharmaceuticals IncCPIX | Pharmaceutical Preparations | $96.9M | +88.1% | $3.9M | Cash-generating | 2.3% | 0 | 2 |
| Immucell Corp /de/ICCC | In Vitro & In Vivo Diagnostic Substances | $95.7M | +73.9% | $8.9M | Cash-generating | 0.2% | 0 | 0 |
| Kazia Therapeutics LtdKZIA | Pharmaceutical Preparations | $94.8M | +11.8% | – | – | 9.7% | 0 | 0 |
| Immunic, INC.IMUX | Pharmaceutical Preparations | $94.7M | −13.2% | $155.1M | 22.9 months | 15.2% | 0 | 0 |
| CellectisCLLS | Biological Products, (No Diagnostic Substances) | $94.7M | −77.4% | $61.5M | 18.7 months | 0.3% | 0 | 0 |
| Polaryx Therapeutics, Inc.PLYX | Pharmaceutical Preparations | $93.2M | – | $11.5M | 26 months | 0.3% | 0 | 0 |
| Atara Biotherapeutics, Inc.ATRA | Biological Products, (No Diagnostic Substances) | $92.7M | −37.6% | $3.2M | 1.5 months | 3.2% | 0 | 0 |
| Insight Molecular Diagnostics Inc.IMDX | In Vitro & In Vivo Diagnostic Substances | $92.6M | −46.5% | $17.8M | 8.9 months | 3.0% | 0 | 0 |
| Anixa Biosciences IncANIX | Pharmaceutical Preparations | $92.5M | −35.1% | $1.4M | 2.4 months | 3.9% | 0 | 0 |
| Research Alliance Corp IIIRACC | Pharmaceutical Preparations | $92.2M | – | $832.8K | – | 0.1% | 0 | 0 |
| Quantum Cyber N.V.QUCY | Pharmaceutical Preparations | $92.1M | −26.5% | $13.4M | 16.5 months | 1.9% | 0 | 0 |
| Neumora Therapeutics, Inc.NMRA | Biological Products, (No Diagnostic Substances) | $88.9M | −72.7% | $116.8M | 7.2 months | 3.6% | 0 | 0 |
| Milestone Pharmaceuticals Inc.MIST | Pharmaceutical Preparations | $88.1M | −63.5% | $169.7M | 40 months | 15.3% | 0 | 1 |
| OnKure Therapeutics, Inc.OKUR | Pharmaceutical Preparations | $87.3M | −22.5% | $166.5M | 39 months | 3.0% | 0 | 0 |
| RallybioRLYB | Pharmaceutical Preparations | $86.7M | +281.5% | $92.8M | 40 months | 0.9% | 0 | 0 |
| Rani Therapeutics Holdings, Inc.RANI | Pharmaceutical Preparations | $85.8M | −60.0% | $4.9M | 3.4 months | 5.5% | 0 | 0 |
| Corbus PharmaceuticalsCRBP | Pharmaceutical Preparations | $85.1M | −77.2% | $23.4M | 3.8 months | 15.8% | 1 | 0 |
| Aardvark Therapeutics, Inc.AARD | Pharmaceutical Preparations | $83.8M | −70.1% | $73.8M | 14.4 months | 2.2% | 0 | 0 |
| Taiko Pharmaceutical4574.T | Pharmaceutical or biotech (Wikidata) | $83.8M | −10.2% | – | – | – | 0 | 0 |
| Tenaya Therapeutics, Inc.TNYA | Biological Products, (No Diagnostic Substances) | $83.7M | −79.4% | $78.1M | 14.6 months | 10.2% | 0 | 0 |
| Ascend Wellness Holdings, Inc.AAWH | Medicinal Chemicals & Botanical Products | $81.9M | −50.8% | $67.0M | Cash-generating | 0.0% | 0 | 0 |
| Fitlife Brands, INC.FTLF | Medicinal Chemicals & Botanical Products | $79.4M | −52.2% | – | – | 0.6% | 0 | 0 |
| Pelthos Therapeutics Inc.PTHS | Biological Products, (No Diagnostic Substances) | $77.3M | −30.3% | $24.2M | 8.3 months | 2.7% | 0 | 0 |
| Zomedica Corp.ZOMDF | Pharmaceutical Preparations | $76.5M | +24.0% | $7.2M | 5.3 months | 0.0% | 0 | 0 |
| Equillium, Inc.EQ | Pharmaceutical Preparations | $75.5M | −18.5% | $57.2M | 36 months | 8.7% | 0 | 0 |
| LifeVantageLFVN | Pharmaceutical Preparations | $75.2M | −31.9% | $14.9M | Cash-generating | 8.5% | 0 | 0 |
| ProMIS Neurosciences Inc.PMN | Pharmaceutical Preparations | $73.8M | −25.1% | $53.4M | 18.0 months | 2.7% | 0 | 0 |
| Neonc Technologies Holdings, INC.NTHI | Pharmaceutical Preparations | $72.9M | −72.8% | $2.0M | 1.1 months | 2.9% | 0 | 0 |
| Acrivon Therapeutics, Inc.ACRV | Pharmaceutical Preparations | $72.6M | −6.3% | $41.4M | 7.7 months | 3.8% | 0 | 0 |
| Zhengye Biotechnology Holding LtdZYBT | Pharmaceutical Preparations | $71.6M | −45.1% | $7.2M | Cash-generating | 0.2% | 0 | 0 |
| Telomir Pharmaceuticals, Inc.TELO | Pharmaceutical Preparations | $71.5M | −33.8% | – | – | 1.2% | 0 | 0 |
| Cardiff Oncology, Inc.CRDF | Biological Products, (No Diagnostic Substances) | $70.0M | −58.9% | $9.2M | 2.9 months | 15.5% | 0 | 0 |
| Medicinova IncMNOV | Pharmaceutical Preparations | $69.9M | +15.4% | $25.4M | 32 months | 0.7% | 1 | 0 |
| Cognition Therapeutics IncCGTX | Biological Products, (No Diagnostic Substances) | $69.5M | −58.0% | $34.0M | 20.2 months | 8.0% | 0 | 0 |
| PMV Pharmaceuticals, Inc.PMVP | Pharmaceutical Preparations | $68.2M | −8.9% | $12.5M | 2.0 months | 5.2% | 0 | 0 |
| Heron Therapeutics, INC. /de/HRTX | Pharmaceutical Preparations | $66.5M | −72.8% | $20.7M | 12.3 months | 24.2% | 0 | 0 |
| Rafael Holdings, Inc.RFL | Pharmaceutical Preparations | $66.0M | −1.5% | $30.5M | 16.1 months | 1.6% | 0 | 0 |
| Citius Oncology, INC.CTOR | Pharmaceutical Preparations | $65.7M | −58.4% | $16.6M | 36 months | 0.3% | 0 | 0 |
| MAIA Biotechnology, Inc.MAIA | Pharmaceutical Preparations | $65.1M | −16.4% | $0 | 0.0 months | 4.4% | 1 | 0 |
| Lexaria Bioscience Corp.LEXX | Pharmaceutical Preparations | $65.1M | −79.0% | $3.5M | 4.8 months | 1.1% | 0 | 0 |
| Spero Therapeutics, Inc.SPRO | Pharmaceutical Preparations | $64.9M | −49.5% | $50.8M | Cash-generating | 1.4% | 0 | 0 |
| Champions OncologyCSBR | Biological Products, (No Diagnostic Substances) | $64.4M | −28.7% | $4.4M | 9.4 months | 0.5% | 0 | 0 |
| Cingulate Inc.CING | Pharmaceutical Preparations | $64.1M | +19.2% | $28.4M | 17.4 months | 7.1% | 0 | 0 |
| Oncolytics BiotechONCY | Pharmaceutical Preparations | $64.0M | −57.4% | $4.1M | 2.2 months | 5.8% | 0 | 0 |
| Apollomics Inc.APLM | Pharmaceutical Preparations | $62.9M | −39.8% | – | – | 0.2% | 0 | 0 |
| biote Corp.BTMD | Medicinal Chemicals & Botanical Products | $61.7M | −62.7% | $11.2M | Cash-generating | 1.9% | 0 | 0 |
| Fortress BiotechFBIO | Pharmaceutical Preparations | $61.6M | −31.5% | $196.6M | Cash-generating | 14.7% | 0 | 0 |
| Biomea Fusion, Inc.BMEA | Pharmaceutical Preparations | $61.6M | −43.8% | $34.8M | 7.4 months | 19.4% | 0 | 0 |
| MindWalkHYFT | Pharmaceutical Preparations | $61.2M | −17.1% | – | – | 1.5% | 0 | 0 |
| XBiotech Inc.XBIT | Pharmaceutical Preparations | $61.1M | −19.5% | $109.5M | 31 months | 1.1% | 0 | 0 |
| Verrica Pharmaceuticals Inc.VRCA | Pharmaceutical Preparations | $60.0M | −15.9% | $11.2M | 9.5 months | 1.1% | 3 | 1 |
| Journey Medical CorpDERM | Pharmaceutical Preparations | $59.5M | −28.5% | $25.6M | 46 months | 26.4% | 0 | 9 |
| OS Therapies IncOSTX | Pharmaceutical Preparations | $59.5M | −30.3% | $205.0K | 0.2 months | 5.6% | 0 | 0 |
| Enzon PharmaceuticalsVISK | Biological Products, (No Diagnostic Substances) | $58.0M | +5685.7% | $7.9M | 4.9 months | – | 0 | 0 |
| Tenax Therapeutics, INC.TENX | Pharmaceutical Preparations | $56.9M | −77.3% | $118.0M | 37 months | 19.2% | 3 | 0 |
| AcelRx Pharmaceuticals (United States)TLPH | Pharmaceutical Preparations | $56.6M | +1.9% | $742.0K | 0.8 months | 1.4% | 0 | 0 |
| Nomad Power Solutions, INC.NMAD | Pharmaceutical Preparations | $56.1M | −22.6% | – | – | 6.3% | 0 | 0 |
| Connect Biopharma Holdings LtdCNTB | Pharmaceutical Preparations | $55.8M | −48.8% | $27.0M | 5.7 months | 5.6% | 0 | 0 |
| Pliant (United States)PLRX | Pharmaceutical Preparations | $55.8M | −42.6% | $24.9M | 3.0 months | 6.9% | 0 | 0 |
| Retrieve Medical Holdings, Inc.RMHI | Pharmaceutical Preparations | $54.9M | −43.5% | – | – | 0.0% | 0 | 0 |
| Xilio Therapeutics, Inc.XLO | Pharmaceutical Preparations | $54.8M | −19.9% | $136.0M | 29 months | 6.2% | 0 | 0 |
| IB Acquisition Corp.IBAC | Commercial Physical & Biological Research | $54.4M | +4.1% | $30.2K | 0.2 months | 0.0% | 0 | 0 |
| Gain Therapeutics, Inc.GANX | Pharmaceutical Preparations | $54.3M | −33.4% | $13.1M | 8.1 months | 7.0% | 0 | 0 |
| Skye Bioscience, Inc.SKYE | Pharmaceutical Preparations | $54.2M | −86.1% | $8.1M | 2.3 months | 0.4% | 0 | 0 |
| PDS Biotechnology CorpPDSB | Pharmaceutical Preparations | $53.9M | +4.0% | $5.6M | 2.9 months | 4.9% | 0 | 0 |
| Yarrow Bioscience, Inc.YARW | Pharmaceutical Preparations | $53.4M | +5.8% | $22.9M | 10.7 months | 7.1% | 0 | 0 |
| Boundless Bio (United States)BOLD | Pharmaceutical Preparations | $52.9M | +69.7% | $20.2M | 5.1 months | 3.4% | 0 | 0 |
| Eloxx Pharmaceuticals, Inc.ELOX | Biological Products, (No Diagnostic Substances) | $50.4M | – | $62.0M | 57 months | 1.3% | 0 | 0 |
| Werewolf Therapeutics, Inc.HOWL | Pharmaceutical Preparations | $50.3M | −35.3% | $22.0M | 5.1 months | 5.2% | 0 | 0 |
| Caribou Biosciences, Inc.CRBU | Biological Products, (No Diagnostic Substances) | $49.4M | −82.5% | $26.2M | 3.1 months | 12.0% | 0 | 0 |
| iBio, Inc.IBIO | Pharmaceutical Preparations | $49.1M | −10.2% | $56.4M | 29 months | 6.5% | 0 | 0 |
| LeonaBio, Inc.LONA | Biological Products, (No Diagnostic Substances) | $48.7M | +42.8% | $32.3M | 7.5 months | 0.2% | 1 | 0 |
| Leef Brands Inc.LEEEF | Medicinal Chemicals & Botanical Products | $48.5M | −20.7% | $5.0M | Cash-generating | 0.2% | 0 | 0 |
| MiNK Therapeutics, Inc.INKT | Biological Products, (No Diagnostic Substances) | $48.4M | −32.3% | $8.8M | 16.7 months | 1.0% | 0 | 0 |
| Rein Therapeutics, Inc.RNTX | Pharmaceutical Preparations | $48.3M | −54.1% | $8.5M | 6.2 months | 0.8% | 0 | 0 |
| ImageneBio, Inc.IMA | Biological Products, (No Diagnostic Substances) | $46.0M | −46.3% | $94.7M | 20.5 months | 0.3% | 0 | 0 |
| Sangamo Therapeutics, IncSGMOQ | Biological Products, (No Diagnostic Substances) | $45.6M | −82.8% | $27.6M | 3.7 months | 2.2% | 0 | 0 |
| Kalaris Therapeutics, Inc.KLRS | Biological Products, (No Diagnostic Substances) | $45.5M | −58.8% | $43.2M | 12.2 months | 1.4% | 0 | 0 |
| Tevogen Inc.TVGN | Biological Products, (No Diagnostic Substances) | $44.8M | −80.4% | $1.1M | 1.1 months | 0.9% | 0 | 0 |
| Serina Therapeutics, Inc.SER | Pharmaceutical Preparations | $42.9M | −64.8% | $23.0M | 15.2 months | 0.2% | 0 | 0 |
| Adicet Bio, Inc.ACET | Pharmaceutical Preparations | $42.6M | −71.2% | $33.1M | 4.4 months | 5.2% | 0 | 0 |
| Clene Inc.CLNN | Pharmaceutical Preparations | $42.5M | −61.1% | $9.7M | 6.4 months | 6.9% | 0 | 0 |
| Inmune Bio, Inc.INMB | Biological Products, (No Diagnostic Substances) | $42.5M | −17.3% | $18.4M | 11.5 months | 9.6% | 0 | 0 |
| Dogwood Therapeutics, Inc.DWTX | Pharmaceutical Preparations | $42.3M | −78.4% | $9.6M | 7.4 months | 0.1% | 0 | 0 |
| Actinium Pharmaceuticals, Inc.ATNM | Pharmaceutical Preparations | $42.3M | −7.9% | $36.5M | 19.1 months | 2.2% | 2 | 0 |
| Annovis Bio, Inc.ANVS | Pharmaceutical Preparations | $41.8M | −50.5% | $18.7M | 8.5 months | 13.8% | 3 | 0 |
| Aldeyra Therapeutics, Inc.ALDX | Pharmaceutical Preparations | $41.6M | −86.9% | $45.1M | 20.8 months | 5.8% | 1 | 0 |
| Elicio Therapeutics, Inc.ELTX | Pharmaceutical Preparations | $39.9M | −83.7% | $23.5M | 7.3 months | 5.9% | 0 | 0 |
| Instil Bio, Inc.TIL | Biological Products, (No Diagnostic Substances) | $39.7M | −69.3% | $5.5M | 2.0 months | 2.3% | 0 | 0 |
| Veru INC.VERU | Pharmaceutical Preparations | $39.6M | −43.5% | $23.9M | 11.5 months | 8.2% | 0 | 0 |
| Grace Therapeutics, Inc.GRCE | Pharmaceutical Preparations | $39.5M | −39.8% | $13.8M | 16.0 months | 8.2% | 1 | 0 |
| Mustang Bio, INC.MBIO | Pharmaceutical Preparations | $39.5M | −75.3% | $15.2M | 37 months | 0.0% | 0 | 0 |
| Celularity IncCELU | Pharmaceutical Preparations | $38.0M | −40.9% | $368.0K | 0.5 months | 1.2% | 0 | 0 |
| Elutia INC.ELUT | Biological Products, (No Diagnostic Substances) | $37.6M | −8.5% | $19.9M | 5.5 months | 0.0% | 0 | 0 |
| Adaptimmune (United Kingdom)ADAPY | Biological Products, (No Diagnostic Substances) | $37.4M | −88.2% | – | – | 0.1% | 0 | 0 |
| Scynexis IncSCYX | Pharmaceutical Preparations | $37.0M | −38.4% | $10.5M | 21.3 months | 6.0% | 0 | 0 |
| Exozymes INC.EXOZ | Biological Products, (No Diagnostic Substances) | $36.3M | −69.2% | $5.7M | 9.8 months | 0.2% | 0 | 0 |
| Lite Strategy, Inc.LITS | Pharmaceutical Preparations | $35.3M | −38.3% | $5.7M | 7.5 months | 0.6% | 0 | 0 |
| CervoMed Inc.CRVO | Pharmaceutical Preparations | $35.2M | −67.1% | $22.5M | 9.8 months | 8.9% | 0 | 0 |
| Incannex Healthcare Inc.IXHL | Pharmaceutical Preparations | $34.7M | −73.5% | $67.7M | 63 months | 3.6% | 0 | 0 |
| CalciMedica, Inc.CALC | Pharmaceutical Preparations | $34.1M | −93.8% | $18.6M | 10.6 months | 0.3% | 0 | 0 |
| Nanoviricides, INC.NNVC | Pharmaceutical Preparations | $33.7M | −12.0% | $2.8M | 4.4 months | 3.6% | 0 | 0 |
| Evaxion A/SEVAX | Biological Products, (No Diagnostic Substances) | $33.4M | −50.7% | $23.2M | 42 months | 0.5% | 0 | 0 |
| Cell Source, Inc.CLCS | Pharmaceutical Preparations | $33.2M | +22.1% | – | – | 0.0% | 0 | 0 |
| Filana Therapeutics, INC.FLNA | Pharmaceutical Preparations | $33.1M | −84.0% | $86.6M | 35 months | 12.2% | 0 | 0 |
| IRulya Therapeutics Inc.QNCX | Biological Products, (No Diagnostic Substances) | $32.6M | −91.7% | $116.0M | 35 months | 5.9% | 0 | 0 |
| Charlie's Holdings, Inc.CHUC | Medicinal Chemicals & Botanical Products | $30.9M | −59.0% | – | – | 0.0% | 0 | 0 |
| Metagenomi Therapeutics, Inc.MGX | Biological Products, (No Diagnostic Substances) | $30.8M | −73.3% | $39.0M | 5.4 months | 3.4% | 0 | 0 |
| Aligos Therapeutics, Inc.ALGS | Biological Products, (No Diagnostic Substances) | $30.6M | −50.9% | $30.4M | 4.3 months | 11.4% | 0 | 0 |
| Rockwell Medical Inc.RMTI | Pharmaceutical Preparations | $30.6M | −35.1% | $10.5M | Cash-generating | 1.8% | 0 | 3 |
| BriaCell Therapeutics Corp.BCTX | Pharmaceutical Preparations | $29.7M | −71.2% | $6.9M | 2.9 months | 9.0% | 1 | 0 |
| China Pharma Holdings, INC.CPHI | Pharmaceutical Preparations | $29.4M | −62.5% | $304.9K | Cash-generating | 0.1% | 0 | 0 |
| bioAffinity Technologies, Inc.BIAF | Commercial Physical & Biological Research | $28.9M | −91.9% | $2.4M | 2.7 months | 1.4% | 0 | 0 |
| Transcode Therapeutics, Inc.RNAZ | Pharmaceutical Preparations | $28.8M | −88.8% | $8.4M | 4.7 months | 0.3% | 0 | 0 |
| Cel-Sci (United States)CVM | Biological Products, (No Diagnostic Substances) | $28.3M | −81.8% | $6.5M | 4.6 months | 3.4% | 0 | 0 |
| BioStem Technologies, Inc.BSEM | Biological Products, (No Diagnostic Substances) | $28.1M | −67.7% | $7.0M | – | 0.6% | 0 | 0 |
| Edesa Biotech, Inc.EDSA | Pharmaceutical Preparations | $26.9M | +18.0% | $10.3M | 15.7 months | 2.1% | 0 | 0 |
| Mira Pharmaceuticals, INC.MIRA | Pharmaceutical Preparations | $26.4M | −61.2% | $3.6M | 10.2 months | 1.0% | 0 | 0 |
| IGC Pharma, Inc.IGC | Pharmaceutical Preparations | $26.0M | −37.2% | $331.0K | 0.8 months | 0.9% | 0 | 0 |
| Valion Bio, Inc.VBIO | Pharmaceutical Preparations | $26.0M | −98.4% | $2.1M | 2.3 months | 0.4% | 0 | 0 |
| Natural Alternatives InternationalNAII | Medicinal Chemicals & Botanical Products | $25.5M | −56.1% | $7.4M | 9.9 months | 0.0% | 0 | 0 |
| Atossa Therapeutics (United States)ATOS | Pharmaceutical Preparations | $25.3M | −82.7% | $26.1M | 9.4 months | 7.9% | 0 | 0 |
| Zivo Bioscience, Inc.ZIVO | Biological Products, (No Diagnostic Substances) | $25.3M | −48.0% | $57.2K | 0.2 months | 0.2% | 0 | 0 |
| NextCure, Inc.NXTC | Pharmaceutical Preparations | $25.3M | −53.8% | $15.3M | 3.7 months | 4.7% | 0 | 0 |
| Seres Therapeutics, Inc.MCRB | Pharmaceutical Preparations | $24.5M | −87.0% | $15.6M | 4.4 months | 3.2% | 0 | 0 |
| Earth Science Tech, Inc.ETST | Pharmaceutical Preparations | $24.4M | −47.7% | $631.1K | Cash-generating | 0.0% | 0 | 0 |
| Abvc Biopharma, INC.ABVC | Pharmaceutical Preparations | $24.4M | −68.7% | $31.9K | 0.1 months | 1.8% | 0 | 0 |
| Matinas BioPharma Holdings, Inc.MTNB | Pharmaceutical Preparations | $23.5M | −8.1% | $761.0K | 1.4 months | 0.4% | 0 | 0 |
| Marimed INC.MRMD | Medicinal Chemicals & Botanical Products | $23.3M | −62.2% | $8.4M | Cash-generating | 0.0% | 0 | 0 |
| Shuttle Pharmaceuticals Holdings, Inc.SHPH | Pharmaceutical Preparations | $23.2M | −86.6% | $90.2K | 0.1 months | 0.4% | 0 | 0 |
| PMGC Holdings Inc.ELAB | Pharmaceutical Preparations | $22.7M | −99.8% | $18.1M | 29 months | 0.3% | 0 | 0 |
| Aytu Biopharma, IncAYTU | Pharmaceutical Preparations | $22.3M | −10.5% | $26.3M | Cash-generating | 3.2% | 0 | 0 |
| Context Therapeutics Inc.CNTX | Pharmaceutical Preparations | $22.0M | −83.3% | $43.0M | 15.7 months | 5.1% | 0 | 0 |
| TherapeuticsMD, Inc.TXMD | Pharmaceutical Preparations | $22.0M | +52.0% | $9.2M | – | 0.2% | 0 | 0 |
| BeyondSpring Inc.BYSI | Pharmaceutical Preparations | $21.8M | −70.1% | $2.7M | 1.7 months | 5.9% | 1 | 0 |
| Scilex Holding CoSCLX | Biological Products, (No Diagnostic Substances) | $21.6M | −68.0% | $566.0K | 2.1 months | 2.0% | 0 | 0 |
| Kyntra Bio, INC.KYNB | Pharmaceutical Preparations | $21.1M | −49.7% | $50.6M | 28 months | 2.5% | 1 | 0 |
| Bio Essence CorpBIOE | Pharmaceutical Preparations | $21.0M | +449.3% | $675 | Cash-generating | – | 0 | 0 |
| Provectus Biopharmaceuticals, INC.PVCT | Pharmaceutical Preparations | $21.0M | −33.5% | $1.2M | 5.4 months | 0.2% | 0 | 0 |
| Akari Therapeutics PlcAKTX | Pharmaceutical Preparations | $21.0M | −71.6% | $7.7M | 8.5 months | 0.6% | 0 | 0 |
| Universe Pharmaceuticals INCUPC | Pharmaceutical Preparations | $20.6M | −27.9% | $33.6B | 80 months | 0.8% | 0 | 0 |
| Optimi Health Corp.OPTH | Pharmaceutical Preparations | $19.9M | – | – | – | 0.5% | 0 | 0 |
| Inhibitor Therapeutics, Inc.INTI | Pharmaceutical Preparations | $19.1M | +129.2% | $515.8K | 2.0 months | – | 0 | 0 |
| Marker Therapeutics, Inc.MRKR | Pharmaceutical Preparations | $18.7M | +9.8% | $11.3M | 17.2 months | 1.0% | 0 | 0 |
| Cocrystal Pharma, Inc.COCP | Pharmaceutical Preparations | $18.2M | −11.7% | $7.0M | 11.1 months | 0.9% | 0 | 0 |
| Neuphoria Therapeutics Inc.NEUP | Pharmaceutical Preparations | $18.0M | −78.5% | $19.9M | 19.3 months | 0.4% | 0 | 0 |
| Black Hawk Acquisition CorpBKHA | Biological Products, (No Diagnostic Substances) | $17.9M | −61.6% | $0 | 0.0 months | 0.0% | 0 | 0 |
| aTyr PharmaATYR | Biological Products, (No Diagnostic Substances) | $16.8M | −83.2% | $16.2M | 3.3 months | 13.1% | 0 | 0 |
| MannatechMTEX | Medicinal Chemicals & Botanical Products | $16.5M | −2.1% | $6.0M | over 10 years | 0.7% | 0 | 0 |
| Quantum Biopharma Ltd.QNTM | Pharmaceutical Preparations | $15.9M | −82.3% | $1.9M | 2.8 months | 5.7% | 0 | 0 |
| Jasper Therapeutics, Inc.JSPR | Biological Products, (No Diagnostic Substances) | $15.8M | −80.6% | $7.3M | 1.3 months | 18.7% | 0 | 0 |
| TScan Therapeutics, Inc.TCRX | Biological Products, (No Diagnostic Substances) | $15.0M | −91.3% | $100.2M | 9.9 months | 3.6% | 1 | 0 |
| Actuate Therapeutics, INC.ACTU | Pharmaceutical Preparations | $14.3M | −92.0% | $4.4M | 2.7 months | 5.5% | 0 | 0 |
| ImugeneIMU.AX | Pharmaceutical or biotech (Wikidata) | $14.3M | −90.8% | – | – | – | 0 | 0 |
| Pasithea Therapeutics Corp.KTTA | Pharmaceutical Preparations | $14.0M | −42.6% | $45.7M | 32 months | 0.5% | 0 | 0 |
| Dyadic International IncDYAI | Biological Products, (No Diagnostic Substances) | $14.0M | −64.0% | $1.4M | 3.0 months | 0.5% | 0 | 0 |
| BioCardia, Inc.BCDA | Biological Products, (No Diagnostic Substances) | $13.9M | −36.6% | $4.1M | 6.6 months | 4.1% | 0 | 0 |
| Allarity Therapeutics, Inc.ALLR | Pharmaceutical Preparations | $13.8M | −39.9% | $17.0M | 12.3 months | 0.7% | 0 | 0 |
| Kairos Pharma, LTD.KAPA | Pharmaceutical Preparations | $13.6M | −93.0% | $2.6M | 8.4 months | 0.5% | 0 | 0 |
| Tvardi Therapeutics, Inc.TVRD | Pharmaceutical Preparations | $13.3M | −84.9% | $15.8M | 8.7 months | 1.7% | 0 | 0 |
| Adia Med, Inc.ADIA | Medicinal Chemicals & Botanical Products | $13.2M | +288.9% | $128.1K | 7.6 months | 0.0% | 0 | 0 |
| Vyome Holdings, IncHIND | Pharmaceutical Preparations | $13.0M | −64.9% | $7.9M | 19.0 months | 0.4% | 0 | 0 |
| Vicapsys Life Sciences, Inc.VICP | Pharmaceutical Preparations | $12.9M | −77.4% | – | – | 0.0% | 0 | 0 |
| America Great HealthAAGH | Pharmaceutical Preparations | $12.7M | +500.0% | $29.3K | 1.8 months | – | 0 | 0 |
| Artelo Biosciences, INC.ARTL | Pharmaceutical Preparations | $12.6M | −97.6% | $4.2M | 6.2 months | 1.0% | 0 | 0 |
| Rocket One Inc.RKTO | Pharmaceutical Preparations | $12.3M | −64.8% | $7.9M | 9.4 months | 4.0% | 0 | 0 |
| Aspire-Lakewood Holdings, Inc.ASBP | Pharmaceutical Preparations | $12.1M | −36.5% | $12.2M | 23.5 months | 1.0% | 0 | 0 |
| Estrella Immunopharma, Inc.ESLA | Biological Products, (No Diagnostic Substances) | $12.1M | −84.1% | $100.0K | 0.1 months | 0.5% | 0 | 0 |
| Lipocine Inc.LPCN | Pharmaceutical Preparations | $12.0M | −51.7% | $5.0M | 5.9 months | 1.2% | 1 | 0 |
| Biofrontera Inc.BFRI | Pharmaceutical Preparations | $11.9M | −16.2% | $4.7M | 6.0 months | 1.0% | 0 | 0 |
| AEON Biopharma, Inc.AEON | Pharmaceutical Preparations | $11.8M | −78.5% | $3.4M | 3.4 months | 4.4% | 0 | 0 |
| Synlogic, INC.SYBX | Pharmaceutical Preparations | $11.8M | −47.5% | $13.2M | 48 months | 0.0% | 0 | 0 |
| Citius Pharmaceuticals, Inc.CTXR | Pharmaceutical Preparations | $11.7M | −70.7% | $17.0M | 5.9 months | 20.4% | 0 | 3 |
| IN8BIO, INC.INAB | Biological Products, (No Diagnostic Substances) | $11.6M | −43.3% | $18.1M | 15.0 months | 0.5% | 0 | 0 |
| Pluri Inc.PLUR | Biological Products, (No Diagnostic Substances) | $11.1M | −78.8% | $3.5M | 2.2 months | 0.2% | 0 | 0 |
| Passage BIO, Inc.PASG | Biological Products, (No Diagnostic Substances) | $11.1M | −57.4% | $24.2M | 9.5 months | 2.8% | 0 | 0 |
| Cellectar Biosciences, Inc.CLRB | Pharmaceutical Preparations | $10.9M | −74.4% | $34.0M | 22.0 months | 1.8% | 1 | 0 |
| Aspira Women's Health Inc.AWHL | In Vitro & In Vivo Diagnostic Substances | $10.7M | −54.9% | $477.0K | 1.3 months | 0.0% | 0 | 0 |
| Dare Bioscience, Inc.DARE | Pharmaceutical Preparations | $10.5M | −66.0% | $12.6M | 15.2 months | 6.0% | 0 | 0 |
| Kiora Pharmaceuticals IncKPRX | Pharmaceutical Preparations | $10.4M | −12.9% | $7.1M | 8.2 months | 0.1% | 0 | 0 |
| Intensity Therapeutics, INC.INTS | Biological Products, (No Diagnostic Substances) | $10.4M | −51.1% | $9.5M | 12.6 months | 1.2% | 1 | 0 |
| Phio Pharmaceuticals Corp.PHIO | Pharmaceutical Preparations | $10.2M | −58.4% | $13.0M | 14.6 months | 0.8% | 0 | 0 |
| Ensysce BiosciencesENSC | Pharmaceutical Preparations | $10.1M | −78.2% | $676.7K | 0.8 months | 5.6% | 1 | 0 |
| Palatin Technologies IncPTN | Pharmaceutical Preparations | $10.1M | −19.7% | $7.5M | 6.6 months | 20.5% | 0 | 0 |
| BullFrog AI Holdings, Inc.BFRG | Pharmaceutical Preparations | $10.0M | −63.3% | $6.9M | 15.3 months | 4.0% | 0 | 0 |
| Biovie INC.BIVI | Pharmaceutical Preparations | $10.0M | −30.8% | $9.0M | 5.7 months | 11.0% | 0 | 0 |
| Tempest Therapeutics, Inc.TPST | Pharmaceutical Preparations | $9.7M | −94.0% | $779.0K | 0.4 months | 3.8% | 1 | 0 |
| Adial Pharmaceuticals, INC.ADIL | Pharmaceutical Preparations | $9.6M | −59.3% | $28.7M | 53 months | 7.0% | 0 | 0 |
| Theriva Biologics, Inc.TOVX | Pharmaceutical Preparations | $9.4M | −51.0% | $11.3M | 9.5 months | 3.7% | 0 | 0 |
| Hepion Pharmaceuticals, Inc.HEPA | Pharmaceutical Preparations | $9.2M | +43.8% | $1.6M | 12.4 months | 0.0% | 0 | 0 |
| Vistagen Therapeutics, Inc.VTGN | Pharmaceutical Preparations | $9.0M | −95.0% | $17.0M | 3.3 months | 8.5% | 2 | 0 |
| Caladrius BiosciencesLSTA | Pharmaceutical Preparations | $8.8M | −59.8% | $10.4M | 9.2 months | 0.4% | 0 | 0 |
| Brainstorm Cell Therapeutics INC.BCLI | Biological Products, (No Diagnostic Substances) | $8.6M | +19.2% | $22.0K | 0.0 months | 0.3% | 1 | 0 |
| Oncotelic Therapeutics, Inc.OTLC | Pharmaceutical Preparations | $8.5M | −81.5% | $409.0K | 3.1 months | 0.0% | 1 | 0 |
| Lantern Pharma Inc.LTRN | Pharmaceutical Preparations | $8.4M | −83.5% | $6.7M | 5.3 months | 3.8% | 0 | 0 |
| Biomerica IncBMRA | In Vitro & In Vivo Diagnostic Substances | $8.3M | −39.8% | $2.7M | 8.3 months | 0.6% | 0 | 0 |
| MetaVia Inc.MTVA | Pharmaceutical Preparations | $8.1M | −88.5% | $12.6M | 10.0 months | 1.8% | 0 | 0 |
| Bolt Biotherapeutics, Inc.BOLT | Pharmaceutical Preparations | $8.1M | −27.0% | $12.9M | 4.5 months | 1.3% | 0 | 0 |
| Karyopharm Therapeutics Inc.KPTI | Pharmaceutical Preparations | $7.9M | −94.1% | $55.0M | 11.2 months | 26.7% | 3 | 0 |
| ZIOPHARM OncologyTCRT | Pharmaceutical Preparations | $7.8M | +0.3% | $124.0K | 0.5 months | 0.4% | 0 | 0 |
| Soligenix, INC.SNGX | Pharmaceutical Preparations | $7.5M | −79.2% | $9.8M | 10.9 months | 0.8% | 0 | 0 |
| InMed Pharmaceuticals Inc.INM | Pharmaceutical Preparations | $7.5M | −35.2% | $2.2M | 3.0 months | 0.6% | 0 | 0 |
| Zeo ScientifiX, Inc.ZEOX | Biological Products, (No Diagnostic Substances) | $7.4M | −52.5% | $1.8M | 17.7 months | 0.0% | 0 | 0 |
| Aprea Therapeutics, Inc.APRE | Pharmaceutical Preparations | $7.1M | −64.0% | $41.2M | 41 months | 4.0% | 0 | 0 |
| CNS Pharmaceuticals, Inc.CNSP | Pharmaceutical Preparations | $7.1M | −47.3% | $20.0M | 15.8 months | 0.1% | 0 | 0 |
| Exicure, INC.XCUR | Pharmaceutical Preparations | $7.0M | −76.4% | $1.7M | 2.5 months | 0.6% | 0 | 0 |
| Senti Biosciences Holdings, Inc.SNTI | Biological Products, (No Diagnostic Substances) | $6.9M | −89.7% | $6.5M | 2.1 months | 1.6% | 0 | 0 |
| Alzamend Neuro, Inc.ALZN | Pharmaceutical Preparations | $6.4M | −40.1% | $7.6M | 13.3 months | 2.3% | 0 | 0 |
| FibroBiologics, Inc.FBLG | Pharmaceutical Preparations | $6.4M | −88.0% | $3.5M | 2.7 months | 7.8% | 0 | 0 |
| Enveric Biosciences, Inc.ENVB | Pharmaceutical Preparations | $6.3M | −84.6% | – | – | 0.3% | 0 | 0 |
| Acurx Pharmaceuticals, Inc.ACXP | Pharmaceutical Preparations | $6.0M | −83.3% | $10.7M | 20.8 months | 2.1% | 0 | 0 |
| Reviva Pharmaceuticals Holdings, INC.RVPH | Pharmaceutical Preparations | $5.9M | −96.1% | $19.9M | 11.8 months | 3.1% | 1 | 0 |
| Traws Pharma, Inc.TRAW | Pharmaceutical Preparations | $5.9M | −86.7% | $5.0M | 3.9 months | 4.5% | 0 | 0 |
| HST Global, Inc.HSTC | Pharmaceutical Preparations | $5.7M | +66750.0% | – | – | – | 0 | 0 |
| Integrated Biopharma IncINBP | Pharmaceutical Preparations | $5.6M | −41.9% | $4.5M | Cash-generating | 0.0% | 0 | 0 |
| Imunon, Inc.IMNN | Pharmaceutical Preparations | $5.6M | −80.5% | $6.9M | 5.5 months | 3.1% | 1 | 0 |
| LianBioLIANY | Pharmaceutical Preparations | $5.5M | −15.0% | – | – | 0.0% | 0 | 0 |
| Apimeds Pharmaceuticals US, Inc.APUS | Pharmaceutical Preparations | $5.3M | −81.1% | $278.4K | 0.3 months | 5.3% | 0 | 0 |
| Cyanotech CorpCYAN | Medicinal Chemicals & Botanical Products | $5.2M | +141.4% | $649.0K | 4.4 months | – | 0 | 0 |
| Pulmatrix, Inc.PULM | Pharmaceutical Preparations | $5.2M | −70.7% | $2.2M | 5.6 months | 1.3% | 0 | 0 |
| AIM ImmunoTech Inc.AIM | Biological Products, (No Diagnostic Substances) | $5.1M | −93.2% | $9.9M | 10.5 months | 4.6% | 0 | 0 |
| Cardio Diagnostics Holdings, Inc.CDIO | In Vitro & In Vivo Diagnostic Substances | $5.0M | −60.8% | $0 | 0.0 months | 0.0% | 0 | 0 |
| NeuroSense Therapeutics Ltd.NRSN | Pharmaceutical Preparations | $4.9M | −89.1% | $166.0K | 0.3 months | 1.4% | 0 | 0 |
| Processa Pharmaceuticals, Inc.PCSA | Pharmaceutical Preparations | $4.8M | −77.4% | $196.3K | 0.2 months | 0.1% | 0 | 0 |
| Creative Medical Technology Holdings, INC.CELZ | Biological Products, (No Diagnostic Substances) | $4.8M | −79.8% | $8.7M | 18.7 months | 2.5% | 0 | 0 |
| Gelteq LtdGELS | Pharmaceutical Preparations | $4.7M | −62.8% | – | – | 5.0% | 0 | 0 |
| Longeveron Inc.LGVN | Pharmaceutical Preparations | $4.7M | −82.0% | $10.1M | 6.6 months | 3.2% | 0 | 0 |
| Jaguar Health, Inc.JAGX | Pharmaceutical Preparations | $4.4M | −99.7% | $3.8M | 6.0 months | 5.6% | 0 | 0 |
| Xenetic Biosciences (United States)XBIO | Pharmaceutical Preparations | $4.4M | −55.3% | $6.5M | 43 months | 0.5% | 0 | 0 |
| Azitra, Inc.AZTR | Pharmaceutical Preparations | $4.4M | −89.8% | $6.7M | 7.6 months | 0.4% | 0 | 0 |
| RedHill Biopharma Ltd.RDHL | Pharmaceutical Preparations | $4.2M | −66.7% | – | – | 2.5% | 0 | 0 |
| Q/c Technologies, INC.QCLS | In Vitro & In Vivo Diagnostic Substances | $4.1M | −88.5% | $307.6K | 0.4 months | 11.6% | 0 | 0 |
| Emmaus Life Sciences, Inc.EMMA | Pharmaceutical Preparations | $4.1M | +386.7% | $2.8M | 53 months | 0.0% | 0 | 2 |
| EnlivexENLV | Pharmaceutical Preparations | $4.1M | −98.8% | $1.9M | 2.2 months | 0.5% | 0 | 0 |
| NuCana plcNCNA | Pharmaceutical Preparations | $4.0M | −80.5% | – | – | 2.5% | 0 | 0 |
| Cadrenal Therapeutics, Inc.CVKD | Pharmaceutical Preparations | $3.9M | −92.0% | $2.4M | 2.6 months | 3.0% | 0 | 0 |
| Kala Pharmaceuticals (United States)KALA | Pharmaceutical Preparations | $3.9M | −99.7% | $229.0K | 0.1 months | 7.0% | 0 | 0 |
| PharmaCyte Biotech, Inc.PMCB | Biological Products, (No Diagnostic Substances) | $3.7M | −64.3% | $17.7M | 54 months | 1.2% | 0 | 0 |
| Polomar Health Services, Inc.PMHS | Pharmaceutical Preparations | $3.5M | −37.5% | $87.8K | 3.3 months | – | 0 | 0 |
| Ctt Pharmaceutical Holdings, INC.CTTH | Pharmaceutical Preparations | $3.5M | −29.3% | $31 | – | 0.0% | 0 | 0 |
| Dermata Therapeutics, Inc.DRMA | Pharmaceutical Preparations | $3.5M | −78.0% | $4.4M | 6.3 months | 2.1% | 0 | 0 |
| CV Sciences, Inc.CVSI | Pharmaceutical Preparations | $3.4M | −62.5% | $266.0K | 14.2 months | 0.0% | 0 | 0 |
| GRI Bio, Inc.GRI | Pharmaceutical Preparations | $3.2M | −97.3% | $10.9M | 10.8 months | 3.2% | 0 | 0 |
| Ernexa Therapeutics Inc.ERNA | Pharmaceutical Preparations | $3.1M | −93.7% | $5.0M | 8.4 months | 1.2% | 0 | 0 |
| Clearmind Medicine Inc.CMND | Pharmaceutical Preparations | $3.1M | −99.8% | $3.9M | 9.9 months | 3.0% | 0 | 0 |
| 60 Degrees Pharmaceuticals, INC.SXTP | Pharmaceutical Preparations | $3.0M | −85.8% | $1.0M | 1.5 months | 3.8% | 0 | 1 |
| Aptevo Therapeutics Inc.APVO | Pharmaceutical Preparations | $2.9M | −94.3% | $9.8M | 4.4 months | 6.6% | 0 | 0 |
| Weed, INC.BUDZ | Commercial Physical & Biological Research | $2.8M | −52.5% | $1.1K | 0.1 months | 0.1% | 0 | 0 |
| Akanda Corp.AKAN | Medicinal Chemicals & Botanical Products | $2.7M | −97.9% | – | – | 1.7% | 0 | 0 |
| Bioxytran, IncBIXT | Pharmaceutical Preparations | $2.7M | −66.1% | – | – | 0.0% | 0 | 0 |
| Lunai Bioworks Inc.LNAI | Pharmaceutical Preparations | $2.5M | −94.9% | $1.7M | 3.9 months | 2.9% | 0 | 0 |
| Aibotics, INC.AIBT | Medicinal Chemicals & Botanical Products | $2.5M | −21.6% | $233.4K | 6.0 months | 0.3% | 0 | 0 |
| HCW Biologics Inc.HCWB | Pharmaceutical Preparations | $2.4M | −94.5% | $741.3K | 0.8 months | 3.3% | 0 | 0 |
| VivoSim Labs, INC.VIVS | Biological Products, (No Diagnostic Substances) | $2.4M | −93.7% | $1.7M | 2.0 months | 4.8% | 0 | 0 |
| Accustem Sciences Inc.ACUT | Pharmaceutical Preparations | $2.4M | −85.5% | – | – | 0.0% | 0 | 0 |
| iSpecimen Inc.ISPC | Commercial Physical & Biological Research | $2.4M | −96.8% | $4.4M | 8.1 months | 6.4% | 0 | 0 |
| Volitionrx LtdVNRX | In Vitro & In Vivo Diagnostic Substances | $2.3M | −98.1% | $2.8M | 1.6 months | 8.8% | 0 | 0 |
| International Stem Cell CORPISCO | Pharmaceutical Preparations | $2.3M | +93.3% | $1.1M | over 10 years | 0.0% | 0 | 0 |
| Procyon CorpPCYN | Pharmaceutical Preparations | $2.2M | +119.5% | – | – | – | 0 | 0 |
| Jupiter Neurosciences, INC.JUNS | Pharmaceutical Preparations | $2.2M | −97.6% | – | – | 4.6% | 0 | 0 |
| Abpro Holdings, Inc.ABPO | Biological Products, (No Diagnostic Substances) | $2.1M | −93.7% | $4.2M | 7.7 months | 0.3% | 0 | 0 |
| IM Cannabis Corp.IMCC | Medicinal Chemicals & Botanical Products | $2.1M | −97.5% | – | – | 5.5% | 0 | 0 |
| BioAtlaBCAB | Biological Products, (No Diagnostic Substances) | $2.0M | −97.1% | $1.5M | 0.5 months | 4.5% | 0 | 0 |
| Propanc Biopharma, Inc.PPCB | Pharmaceutical Preparations | $2.0M | −99.2% | – | – | 1.1% | 0 | 0 |
| Vaccinex, INC.VCNX | Pharmaceutical Preparations | $2.0M | +57.3% | – | – | 0.1% | 0 | 0 |
| Calidi Biotherapeutics, Inc.CLDI | Biological Products, (No Diagnostic Substances) | $2.0M | −97.0% | $4.3M | 2.8 months | 9.0% | 0 | 0 |
| Oragenics IncOGEN | Pharmaceutical Preparations | $1.9M | −66.3% | $3.9M | 5.0 months | 18.7% | 0 | 0 |
| Silo Pharma, Inc.SILO | Pharmaceutical Preparations | $1.8M | −86.3% | $3.3M | 10.2 months | 2.2% | 0 | 0 |
| Virax Biolabs Group LtdVRAX | In Vitro & In Vivo Diagnostic Substances | $1.8M | −90.9% | – | – | 0.5% | 0 | 0 |
| XORTX Therapeutics Inc.XRTX | Pharmaceutical Preparations | $1.8M | −81.5% | – | – | 3.5% | 0 | 0 |
| Genprex, Inc.GNPX | Pharmaceutical Preparations | $1.7M | −99.5% | $15.2M | 12.7 months | 11.8% | 0 | 0 |
| GeoVax Labs, Inc.GOVX | Pharmaceutical Preparations | $1.7M | −98.3% | $3.1M | 2.0 months | 3.8% | 0 | 0 |
| Onconetix, Inc.ONCO | Pharmaceutical Preparations | $1.7M | −99.7% | $5.9M | 7.3 months | 12.4% | 0 | 0 |
| Lftd Partners INC.LIFD | Pharmaceutical Preparations | $1.5M | −60.0% | $1.5M | Cash-generating | 0.0% | 0 | 0 |
| Avenue Therapeutics, INC.ATXI | Pharmaceutical Preparations | $1.4M | −41.9% | $1.9M | 21.5 months | 0.0% | 0 | 0 |
| Protagenic Therapeutics, Inc.\newPTIX | Pharmaceutical Preparations | $1.4M | −76.3% | $566.0K | 3.4 months | 0.7% | 0 | 0 |
| Lakewood-Amedex Biotherapeutics Inc.LABT | Pharmaceutical Preparations | $1.4M | – | $2.6M | – | 5.5% | 0 | 0 |
| Panacea Life Sciences Holdings, INC.PLSH | Medicinal Chemicals & Botanical Products | $1.2M | −5.7% | – | – | – | 0 | 0 |
| Axim Biotechnologies, INC.AXIM | Pharmaceutical Preparations | $996.5K | −52.9% | – | – | 0.0% | 0 | 0 |
| Sunshine Biopharma Inc.SBFM | Pharmaceutical Preparations | $930.6K | −98.8% | $13.7M | 29 months | 3.4% | 0 | 0 |
| Nexentis Technologies Inc.NXTS | Pharmaceutical Preparations | $916.0K | −97.7% | $7.6M | 20.7 months | 2.6% | 0 | 0 |
| Evofem Biosciences, Inc.EVFM | Pharmaceutical Preparations | $888.0K | −33.0% | $285.0K | 13.6 months | 0.0% | 0 | 2 |
| Biodexa Pharmaceuticals PlcBDRX | Pharmaceutical Preparations | $887.0K | −99.0% | – | – | 0.8% | 0 | 0 |
| Skinvisible, INC.SKVI | Pharmaceutical Preparations | $843.0K | −71.6% | $4.0K | 6.3 months | – | 0 | 0 |
| Silexion Therapeutics CorpSLXN | Biological Products, (No Diagnostic Substances) | $801.8K | −99.6% | $2.2M | 2.2 months | 88.6% | 0 | 0 |
| Curis IncCRIS | Biological Products, (No Diagnostic Substances) | $794.0K | −98.8% | $5.1M | 2.1 months | 8.6% | 0 | 0 |
| BioXcel Therapeutics, Inc.BTAIQ | Pharmaceutical Preparations | $782.6K | −98.9% | $12.8M | 2.7 months | 6.3% | 0 | 0 |
| Decoy Therapeutics Inc.DCOY | Pharmaceutical Preparations | $769.8K | −97.6% | $8.3M | 15.2 months | 22.9% | 0 | 0 |
| SciSparcSPRC | Pharmaceutical Preparations | $761.1K | −95.7% | – | – | 2.2% | 0 | 0 |
| China SXT Pharmaceuticals, Inc.SXTC | Pharmaceutical Preparations | $739.5K | −100.0% | $28.2M | 84 months | 0.6% | 0 | 0 |
| Nutra Pharma CorpNPHC | Medicinal Chemicals & Botanical Products | $716.0K | 0.0% | $12.2K | 0.1 months | – | 0 | 0 |
| Target Group Inc.CBDY | Medicinal Chemicals & Botanical Products | $431.9K | −56.2% | $14.0K | 0.5 months | 0.0% | 0 | 0 |
| Cero Therapeutics Holdings, INC.CERO | Biological Products, (No Diagnostic Substances) | $429.8K | −99.7% | $862.8K | 0.6 months | 0.0% | 0 | 0 |
| ZyVersa Therapeutics, Inc.ZVSA | Pharmaceutical Preparations | $388.6K | −64.4% | $302.7K | 0.9 months | 1.7% | 0 | 0 |
| Bioadaptives, INC.BDPT | Pharmaceutical Preparations | $354.5K | −93.3% | $29.2K | 0.7 months | – | 0 | 0 |
| CNBX Pharmaceuticals Inc.CNBX | Pharmaceutical Preparations | $321.2K | −60.0% | $9.5K | 0.6 months | 0.0% | 0 | 0 |
| Neutra Corp.NTRR | Medicinal Chemicals & Botanical Products | $291.8K | −50.0% | – | – | – | 0 | 0 |
| Functional Brands Inc.MEHA | Medicinal Chemicals & Botanical Products | $285.7K | – | $352.1K | 2.3 months | 0.5% | 0 | 0 |
| Foxo Technologies INC.FOXO | Commercial Physical & Biological Research | $182.4K | −96.2% | $58.4K | 0.2 months | 0.4% | 0 | 0 |
| Regen BioPharma IncRGBP | Pharmaceutical Preparations | $167.5K | −99.2% | $239 | 0.0 months | 0.0% | 0 | 0 |
| CDT Equity Inc.CDT | Pharmaceutical Preparations | $141.6K | −100.0% | $747.0K | 0.7 months | 4.9% | 0 | 0 |
| Ocean Biomedical, Inc.OCEA | Pharmaceutical Preparations | $139.4K | −80.0% | – | – | 0.0% | 0 | 0 |
| ProPhase LabsPRPH | Pharmaceutical Preparations | $138.8K | −99.8% | $20.0K | 0.0 months | 0.5% | 0 | 0 |
| Synergy CHC Corp.SNYRQ | Medicinal Chemicals & Botanical Products | $119.2K | −99.7% | $292.1K | 0.9 months | 4.5% | 0 | 0 |
| Petros Pharmaceuticals, Inc.PTPI | Pharmaceutical Preparations | $114.4K | −88.3% | $3.5M | 7.1 months | 0.1% | 0 | 0 |
| ProtoKinetix, Inc.PKTX | Pharmaceutical Preparations | $82.3K | −96.2% | $1.1K | 0.1 months | – | 0 | 0 |
| Anebulo Pharmaceuticals, Inc.ANEB | Pharmaceutical Preparations | $40.8K | −100.0% | $9.0M | 18.3 months | 1.0% | 0 | 0 |
| One World Products, Inc.OWPC | Pharmaceutical Preparations | $36.0K | −98.2% | – | – | – | 0 | 0 |
| Windtree Therapeutics Inc /de/WINT | Biological Products, (No Diagnostic Substances) | $33.7K | −99.2% | $204.0K | 0.2 months | 0.0% | 0 | 0 |
| Bio-Path Holdings, INC.BPTH | Pharmaceutical Preparations | $15.1K | −99.6% | $12.0K | 0.0 months | 0.0% | 0 | 0 |
| Aditxt, Inc.ADTX | Pharmaceutical Preparations | $816 | −100.0% | $268.9K | 0.2 months | – | 0 | 0 |
| Trevena IncTRVN | Pharmaceutical Preparations | $432 | −95.8% | – | – | 0.4% | 0 | 1 |
| Keenova Therapeutics plc | Pharmaceutical Preparations | – | – | $963.7M | Cash-generating | – | 0 | 0 |
| Catalyst PharmaceuticalsCPRX | Pharmaceutical Preparations | – | – | $755.9M | Cash-generating | – | 0 | 4 |
| Dyne Therapeutics, Inc.DYN | Pharmaceutical Preparations | – | – | $676.1M | 18.3 months | – | 2 | 0 |
| Terns Pharmaceuticals, Inc. | Pharmaceutical Preparations | – | – | $524.7M | 77 months | – | 0 | 0 |
| Sinovac BiotechSVA | Pharmaceutical Preparations | – | – | $488.2M | 11.4 months | – | 15 | 0 |
| Metsera, Inc. | Pharmaceutical Preparations | – | – | $448.5M | 54 months | – | 0 | 0 |
| Apellis Pharmaceuticals, Inc. | Pharmaceutical Preparations | – | – | $405.2M | Cash-generating | – | 2 | 2 |
| Avidity Biosciences, Inc. | Pharmaceutical Preparations | – | – | $382.5M | 7.1 months | – | 3 | 0 |
| Merus N.V. | Pharmaceutical Preparations | – | – | $367.5M | 23.7 months | – | 0 | 0 |
| Cidara TherapeuticsCDTX | Biological Products, (No Diagnostic Substances) | – | – | $293.7M | 20.0 months | – | 1 | 0 |
| Theravance Biopharma, Inc.TBPH | Pharmaceutical Preparations | – | – | $219.8M | Cash-generating | – | 1 | 1 |
| Amicus TherapeuticsFOLD | Pharmaceutical Preparations | – | – | $214.0M | Cash-generating | – | 4 | 3 |
| KalVista Pharmaceuticals, Inc. | Pharmaceutical Preparations | – | – | $213.8M | 16.8 months | – | 0 | 0 |
| Day One Biopharmaceuticals, Inc. | Pharmaceutical Preparations | – | – | $197.1M | 22.8 months | – | 1 | 0 |
| Akero Therapeutics, Inc. | Pharmaceutical Preparations | – | – | $176.0M | 9.2 months | – | 3 | 0 |
| AtaiBeckley Inc. | Pharmaceutical Preparations | – | – | $168.8M | 19.1 months | – | 0 | 0 |
| Dynavax Technologies Corp | Pharmaceutical Preparations | – | – | $160.2M | Cash-generating | – | 0 | 0 |
| Nuvalent, Inc. | Pharmaceutical Preparations | – | – | $159.7M | 6.1 months | – | 0 | 0 |
| Esperion TherapeuticsESPR | Pharmaceutical Preparations | – | – | $156.2M | 103 months | – | 0 | 0 |
| Soleno Therapeutics Inc | Pharmaceutical Preparations | – | – | $133.0M | Cash-generating | – | 0 | 0 |
| Apogee Therapeutics, Inc. | Biological Products, (No Diagnostic Substances) | – | – | $105.6M | 5.4 months | – | 0 | 0 |
| Catabasis PharmaceuticalsCATB | Pharmaceutical Preparations | – | – | $96.3M | 14.2 months | – | 0 | 0 |
| XOMA Royalty Corp | Pharmaceutical Preparations | – | – | $85.6M | Cash-generating | – | 0 | 0 |
| Arcellx, Inc. | Biological Products, (No Diagnostic Substances) | – | – | $80.3M | 4.6 months | – | 0 | 0 |
| Avadel PharmaceuticalsAVDL | Pharmaceutical Preparations | – | – | $79.8M | 20.4 months | – | 0 | 0 |
| Repare Therapeutics Inc. | Pharmaceutical Preparations | – | – | $72.8M | 11.4 months | – | 0 | 0 |
| Kezar Life Sciences, Inc. | Pharmaceutical Preparations | – | – | $66.2M | 18.9 months | – | 0 | 0 |
| Centessa Pharmaceuticals plc | Pharmaceutical Preparations | – | – | $62.4M | 3.6 months | – | 1 | 0 |
| Barinthus Biotherapeutics plc. | Pharmaceutical Preparations | – | – | $59.3M | 19.5 months | – | 0 | 0 |
| Mural Oncology plc | Pharmaceutical Preparations | – | – | $58.9M | 5.5 months | – | 0 | 0 |
| Mersana Therapeutics (United States) | Pharmaceutical Preparations | – | – | $56.4M | 8.2 months | – | 0 | 0 |
| Crinetics Pharmaceuticals | Pharmaceutical Preparations | – | – | $55.5M | 1.6 months | – | 3 | 0 |
| LAVA Therapeutics NV | Pharmaceutical Preparations | – | – | $49.7M | 30 months | – | 0 | 0 |
| Forte Biosciences, Inc. | Pharmaceutical Preparations | – | – | $49.6M | 10.0 months | – | 0 | 0 |
| RAPT Therapeutics, Inc. | Pharmaceutical Preparations | – | – | $37.9M | 5.5 months | – | 0 | 0 |
| Assertio Holdings, Inc. | Pharmaceutical Preparations | – | – | $33.7M | 57 months | – | 0 | 0 |
| Ventyx Biosciences, Inc. | Pharmaceutical Preparations | – | – | $32.0M | 2.9 months | – | 0 | 0 |
| IO Biotech, Inc. | Pharmaceutical Preparations | – | – | $30.7M | 4.5 months | – | 1 | 0 |
| Atai Beckley N.V. | Pharmaceutical Preparations | – | – | $30.4M | 4.4 months | – | 0 | 0 |
| Avalanche BiotechnologiesADVM | Biological Products, (No Diagnostic Substances) | – | – | $26.1M | 3.4 months | – | 0 | 0 |
| OmniAb, Inc.OABIW | Commercial Physical & Biological Research | – | – | $24.3M | 11.5 months | – | 0 | 0 |
| Bioharvest Sciences INC.BHST | Pharmaceutical Preparations | – | −83.5% | $23.0M | 38 months | – | 0 | 0 |
| Generation Bio Co. | Pharmaceutical Preparations | – | – | $21.9M | 3.0 months | – | 0 | 0 |
| Inotiv, Inc. | Commercial Physical & Biological Research | – | – | $15.2M | 16.0 months | – | 0 | 0 |
| Regencell BioscienceRGC | Medicinal Chemicals & Botanical Products | – | −42.3% | $14.2M | 22.1 months | – | 0 | 0 |
| Applied Therapeutics, Inc. | Pharmaceutical Preparations | – | – | $11.9M | 1.7 months | – | 1 | 0 |
| Evoke Pharma Inc | Pharmaceutical Preparations | – | – | $11.6M | 25 months | – | 0 | 0 |
| Revelation Biosciences, INC.REVB | Pharmaceutical Preparations | – | – | $11.5M | 15.9 months | – | 0 | 0 |
| Iterum Therapeutics plc | Pharmaceutical Preparations | – | – | $11.0M | 4.9 months | – | 0 | 1 |
| Lomond Therapeutics Holdings, Inc. | Pharmaceutical Preparations | – | – | $10.9M | 4.9 months | – | 0 | 0 |
| Ionetix Corp / DE / | In Vitro & In Vivo Diagnostic Substances | – | – | $10.9M | – | – | 0 | 0 |
| BGM Group Ltd.BGM | Pharmaceutical Preparations | – | −97.1% | $9.8M | 50 months | – | 0 | 0 |
| Kitov PharmaPPBT | Pharmaceutical Preparations | – | −81.8% | $8.7M | 18.5 months | – | 0 | 0 |
| Moleculin Biotech, Inc.MBRX | Pharmaceutical Preparations | – | – | $7.3M | 3.6 months | – | 1 | 0 |
| Clearside Biomedical, Inc. | Pharmaceutical Preparations | – | – | $6.8M | 3.3 months | – | 0 | 0 |
| CQENS Technologies Inc. | Pharmaceutical Preparations | – | – | $6.7M | 19.5 months | – | 0 | 0 |
| Bon Natural Life LtdBON | Medicinal Chemicals & Botanical Products | – | −44.6% | $6.3M | Cash-generating | – | 0 | 0 |
| Vitro Biopharma, Inc. | Biological Products, (No Diagnostic Substances) | – | – | $5.7M | 21.4 months | – | 0 | 0 |
| CASI Pharmaceuticals, Inc.CASIF | Pharmaceutical Preparations | – | −94.2% | $5.6M | 3.3 months | – | 0 | 0 |
| Can Fite BiopharmaCANF | Pharmaceutical Preparations | – | −81.9% | $5.5M | 7.4 months | – | 2 | 0 |
| Galera Therapeutics, Inc. | Pharmaceutical Preparations | – | – | $5.5M | 14.1 months | – | 0 | 0 |
| Sonnet BioTherapeutics Holdings, Inc. | Pharmaceutical Preparations | – | – | $5.1M | 4.8 months | – | 0 | 0 |
| OKYO Pharma LtdOKYO | Biological Products, (No Diagnostic Substances) | – | −37.5% | $4.6M | 30 months | – | 1 | 0 |
| Galmed Pharmaceuticals Ltd.EOCN | Pharmaceutical Preparations | – | −74.4% | $4.0M | 7.6 months | – | 0 | 0 |
| Bioline Rx Ltd.BLRX | Pharmaceutical Preparations | – | −46.9% | $3.2M | 4.8 months | – | 0 | 0 |
| PRF Technologies Ltd.PRFX | Pharmaceutical Preparations | – | −88.2% | $3.1M | 9.5 months | – | 0 | 0 |
| Carisma Therapeutics Inc. | Pharmaceutical Preparations | – | – | $2.8M | 0.6 months | – | 0 | 0 |
| NewcelX Ltd.NCEL | Pharmaceutical Preparations | – | −84.0% | $2.2M | 9.5 months | – | 0 | 0 |
| Lipella Pharmaceuticals INC.LIPO | Pharmaceutical Preparations | – | −99.9% | $1.9M | 5.6 months | – | 0 | 0 |
| Scinai Immunotherapeutics Ltd.SCNI | Biological Products, (No Diagnostic Substances) | – | −94.8% | $1.7M | 3.3 months | – | 0 | 0 |
| CytoMed Therapeutics LtdGDTC | Pharmaceutical Preparations | – | −62.9% | $1.6M | 6.8 months | – | 0 | 0 |
| Nasus Pharma LtdNSRX | Pharmaceutical Preparations | – | −59.0% | $1.2M | 3.0 months | – | 1 | 0 |
| Jyong Biotech Ltd.MENS | Pharmaceutical Preparations | – | −96.8% | $1.2M | 4.6 months | – | 0 | 0 |
| Aptose Biosciences Inc. | Biological Products, (No Diagnostic Substances) | – | – | $935.0K | 0.4 months | – | 0 | 0 |
| Revium Rx.RVRC | Pharmaceutical Preparations | – | +175.0% | $842.0K | – | – | 0 | 0 |
| Adaptin Bio, INC.APTN | Biological Products, (No Diagnostic Substances) | – | – | $670.5K | 2.6 months | – | 0 | 0 |
| Heat BiologicsHTBX | Pharmaceutical Preparations | – | – | $581.6K | 0.3 months | – | 0 | 0 |
| Healthy Extracts INC.HYEX | Medicinal Chemicals & Botanical Products | – | −18.6% | $190.0K | Cash-generating | – | 0 | 0 |
| Kaya Holdings, Inc. | Pharmaceutical Preparations | – | – | $26.1K | 0.4 months | – | 0 | 0 |
| Bespoke Extracts, Inc.BSPK | Pharmaceutical Preparations | – | −99.8% | $16.7K | 0.7 months | – | 0 | 0 |
| China Foods Holdings Ltd.CFOO | Medicinal Chemicals & Botanical Products | – | +58.2% | $15.9K | 0.6 months | – | 0 | 0 |
| Vitaspring Biomedical CO. LTD.VSBC | Commercial Physical & Biological Research | – | −96.8% | $13.4K | Cash-generating | – | 0 | 0 |
| Regenerex Pharma, INC. | Pharmaceutical Preparations | – | – | $11.7K | 0.1 months | – | 0 | 0 |
| Voyager Acquisition Corp./Cayman Islands | Biological Products, (No Diagnostic Substances) | – | – | $6.1K | Cash-generating | – | 0 | 0 |
| BioKey (Cayman), Inc. | Pharmaceutical Preparations | – | – | $4.6K | – | – | 0 | 0 |
| REST EZ Inc. | Pharmaceutical Preparations | – | – | $3.9K | Cash-generating | – | 0 | 0 |
| TFA Therapeutics, Inc.RAJAF | Medicinal Chemicals & Botanical Products | – | 0.0% | $3.2K | 1.1 months | – | 0 | 0 |
| Nika Pharmaceuticals, IncNIKA | Pharmaceutical Preparations | – | −14.4% | $2.9K | 0.4 months | – | 0 | 0 |
| Burzynski Research Institute Inc | In Vitro & In Vivo Diagnostic Substances | – | – | $2.2K | 0.1 months | – | 0 | 0 |
| Raphael Pharmaceutical Inc.RAPH | Medicinal Chemicals & Botanical Products | – | +277.5% | $1.0K | 0.3 months | – | 0 | 0 |
| Fuss Brands Corp. | Pharmaceutical Preparations | – | – | $633 | 0.0 months | – | 0 | 0 |
| Cannapharmarx, INC.CPMD | Pharmaceutical Preparations | – | −58.3% | $555 | 0.0 months | – | 0 | 0 |
| Trafalgar International, INC.GCAN | Pharmaceutical Preparations | – | – | $111 | 0.0 months | – | 0 | 0 |
| Cannabis Bioscience International Holdings, Inc.CBIH | Commercial Physical & Biological Research | – | −60.0% | $90 | 0.0 months | – | 0 | 0 |
| Cannaisseur Group Inc.TCRG | Medicinal Chemicals & Botanical Products | – | – | $41 | 0.0 months | – | 0 | 0 |
| Agentix Corp.AGTX | Biological Products, (No Diagnostic Substances) | – | −59.9% | $38 | 0.0 months | – | 0 | 0 |
| Mosaic ImmunoEngineering Inc.CPMV | Biological Products, (No Diagnostic Substances) | – | −19.2% | $26 | 0.0 months | – | 0 | 0 |
| ARIAD PharmaceuticalsARIA | Biological Products, (No Diagnostic Substances) | – | – | – | – | – | 0 | 0 |
| Trinity Biotech PLCTRIB | In Vitro & In Vivo Diagnostic Substances | – | −72.4% | – | – | – | 0 | 0 |
| Gelstat CorpGSAC | Pharmaceutical Preparations | – | −25.0% | – | – | – | 0 | 0 |
| Nymox Pharmaceutical CorpNYMXF | In Vitro & In Vivo Diagnostic Substances | – | −56.2% | – | – | – | 0 | 0 |
| XTL BioXTLB | Pharmaceutical Preparations | – | −61.1% | – | – | – | 0 | 0 |
| Biomolecular Life Holdings, INC.BIOM | Pharmaceutical Preparations | – | −19.0% | – | – | – | 0 | 0 |
| Alterity Therapeutics LtdATHE | Pharmaceutical Preparations | – | −48.2% | – | – | – | 0 | 0 |
| Medicure IncMCUJF | Pharmaceutical Preparations | – | +297.4% | – | – | – | 1 | 3 |
| GlobeImmuneGBIM | Pharmaceutical Preparations | – | 0.0% | – | – | – | 0 | 0 |
| Anthera PharmaceuticalsANTH | Pharmaceutical Preparations | – | 0.0% | – | – | – | 0 | 0 |
| Avricore Health Inc.AVCRF | Pharmaceutical Preparations | – | −97.7% | – | – | – | 0 | 0 |
| Complete GenomicsGNOM | Commercial Physical & Biological Research | – | +53.3% | – | – | – | 0 | 0 |
| Green Planet Bio Engineering Co. Ltd.GPLB | Biological Products, (No Diagnostic Substances) | – | −78.0% | $0 | 0.0 months | – | 0 | 0 |
| Curative Biotechnology IncCUBT | Biological Products, (No Diagnostic Substances) | – | −24.2% | – | – | – | 0 | 0 |
| Glucose Health, Inc.GLUC | Medicinal Chemicals & Botanical Products | – | +1156.9% | – | – | – | 0 | 0 |
| BetterLife Pharma Inc.BETRF | Pharmaceutical Preparations | – | +308.7% | – | – | – | 0 | 0 |
| ImmutepIMMP | Pharmaceutical Preparations | – | +51.7% | – | – | – | 0 | 0 |
| Addex Therapeutics Ltd.ADXN | Pharmaceutical Preparations | – | −73.3% | – | – | – | 0 | 0 |
| Innate Pharma SAIPHA | Biological Products, (No Diagnostic Substances) | – | −31.4% | – | – | – | 0 | 1 |
| Altamira Therapeutics Ltd.CYTOF | Pharmaceutical Preparations | – | +12.5% | – | – | – | 0 | 0 |
| Grey Matters Health Inc.AGNPF | Pharmaceutical Preparations | – | −47.4% | – | – | – | 0 | 0 |
| Immuron LtdIMRN | Pharmaceutical Preparations | – | −57.3% | – | – | – | 0 | 0 |
| Bonus Biogroup Ltd.BONS.TA | Biological Products, (No Diagnostic Substances) | – | −24.9% | – | – | – | 0 | 0 |
| PyroGenesis Canada Inc.PYRGF | Pharmaceutical Preparations | – | −4.9% | – | – | – | 0 | 0 |
| Molecular PartnersMOLN | Biological Products, (No Diagnostic Substances) | – | −6.6% | – | – | – | 0 | 0 |
| CBD Life Sciences Inc.CBDL | Medicinal Chemicals & Botanical Products | – | −50.0% | – | – | – | 0 | 0 |
| PureTech VenturesPTCHF | Pharmaceutical Preparations | – | −11.9% | – | – | – | 0 | 0 |
| Medicenna Therapeutics Corp.MDNAF | Pharmaceutical Preparations | – | −53.5% | – | – | – | 0 | 0 |
| Opthea LimitedCKDXF | Biological Products, (No Diagnostic Substances) | – | −97.7% | – | – | – | 0 | 0 |
| Genenta Science S.p.A.GNTA | Biological Products, (No Diagnostic Substances) | – | −79.6% | – | – | – | 0 | 0 |
| Beroni Group LtdBNIGF | Pharmaceutical Preparations | – | 0.0% | – | – | – | 0 | 0 |
| MindMaze Therapeutics Holding SAMMTZF | Pharmaceutical Preparations | – | −94.4% | – | – | – | 0 | 0 |
| Intercure Ltd.INCR | Pharmaceutical Preparations | – | −40.6% | – | – | – | 0 | 0 |
| INNOCAN PHARMA CorpINNPF | Pharmaceutical Preparations | – | −89.4% | – | – | – | 0 | 0 |
| Adastra Holdings Ltd.XTXXF | Pharmaceutical Preparations | – | −98.6% | – | – | – | 0 | 0 |
| Radiopharm Theranostics LtdRADX | Pharmaceutical Preparations | – | −85.5% | – | – | – | 0 | 0 |
| Asep Medical Holdings Inc.SEPSF | In Vitro & In Vivo Diagnostic Substances | – | −97.2% | – | – | – | 0 | 0 |
| Psyence Biomedical LTD.PBM | Pharmaceutical Preparations | – | −97.0% | – | – | – | 0 | 0 |
| Beacon Topco, INC.CLYD | Pharmaceutical Preparations | – | – | $0 | – | – | 0 | 0 |
| Eagle PharmaceuticalsEGRX | Pharmaceutical or biotech (Wikidata) | – | −41.0% | – | – | – | 0 | 0 |
| OrexoORXOF | Pharmaceutical or biotech (Wikidata) | – | −73.1% | – | – | – | 0 | 0 |
| Guilin Sanjin Pharmaceutical Company Limited002275.SZ | Pharmaceutical or biotech (Wikidata) | – | −19.2% | – | – | – | 0 | 0 |
| Neptunus Biology000078.SZ | Pharmaceutical or biotech (Wikidata) | – | −45.8% | – | – | – | 0 | 0 |
| IpsenIPSEY | Pharmaceutical or biotech (Wikidata) | – | +24.2% | – | – | – | 10 | 6 |
| Wakamoto Pharmaceutical4512.T | Pharmaceutical or biotech (Wikidata) | – | +5.9% | – | – | – | 0 | 0 |
| Morishita Jintan4524.T | Pharmaceutical or biotech (Wikidata) | – | +3.2% | – | – | – | 0 | 0 |
| Nan Liu Enterprise Company Limited6504.TW | Pharmaceutical or biotech (Wikidata) | – | −16.9% | – | – | – | 0 | 0 |
| NKGen Biotech Inc. (United States)NKGN | Pharmaceutical or biotech (Wikidata) | – | 0.0% | – | – | – | 0 | 0 |
| Il-Yang Pharmaceutical (South Korea)007570.KS | Pharmaceutical or biotech (Wikidata) | – | −44.1% | – | – | – | 0 | 0 |
| NurExone Biologic Inc.J90.F | Pharmaceutical or biotech (Wikidata) | – | −35.7% | – | – | – | 0 | 0 |
| Mayinglong Pharmaceutical Group600993.SS | Pharmaceutical or biotech (Wikidata) | – | −15.3% | – | – | – | 0 | 0 |
| Sartorius AGSRT3.F | Pharmaceutical or biotech (Wikidata) | – | +13.0% | – | – | – | 0 | 0 |
| BeiersdorfBDRFF | Pharmaceutical or biotech (Wikidata) | – | −11.6% | – | – | – | 0 | 0 |
| Prescient TherapeuticsPTX.AX | Pharmaceutical or biotech (Wikidata) | – | +30.9% | – | – | – | 0 | 0 |
| Rafa Laboratories, Ltd.RAFA.TA | Pharmaceutical or biotech (Wikidata) | – | – | – | – | – | 0 | 2 |
| BiohitBIOBV.HE | Pharmaceutical or biotech (Wikidata) | – | −28.1% | – | – | – | 0 | 0 |
| Biotie TherapiesBITI | Pharmaceutical or biotech (Wikidata) | – | −8.3% | – | – | – | 0 | 0 |
| CK Life Sciences0775.HK | Pharmaceutical or biotech (Wikidata) | – | −44.6% | – | – | – | 0 | 0 |
| Global Bio-Chem0809.HK | Pharmaceutical or biotech (Wikidata) | – | −54.4% | – | – | – | 0 | 0 |
| Lijun International Pharmaceutical (Holding) Co. Ltd.2005.HK | Pharmaceutical or biotech (Wikidata) | – | −5.2% | – | – | – | 0 | 0 |
| DermapharmDMP.F | Pharmaceutical or biotech (Wikidata) | – | +16.2% | – | – | – | 0 | 0 |
| UCBUCBJF | Pharmaceutical or biotech (Wikidata) | – | −20.9% | – | – | – | 18 | 30 |
| Tempo Scan PacificTSPC.JK | Pharmaceutical or biotech (Wikidata) | – | −8.2% | – | – | – | 0 | 0 |
Companies: SEC industry codes 2833 to 2836 and 8731 from SEC EDGAR, plus companies outside the SEC whose Wikidata industry is pharmaceuticals or biotechnology. Runway on cash as described above. Short % from FINRA as of Sep 30, 2026. Also: active phase 3 trials (recruiting, active or not yet recruiting) from ClinicalTrials.gov; original NDA and BLA approvals on file at Drugs@FDA.



























































