Biggest gainers
The 100 biggest rises on each stock’s latest session among companies worth at least $300 million that trade at least $1 million a day, listed in the United States.
U.S. prices are closes from Oct 19; 490 of them, mostly large companies, updated to 3:01 p.m. ET on Oct 21. Snapshot taken Oct 21, 2026 Source: On the record price snapshot, SEC share counts
100 biggest gainers
Microcaps are left out: a stock needs a market value of at least $300M and at least $1M of trading a day to be listed, and a price of $1 or more. 1D is each stock’s move on its latest session in the snapshot: Oct 19 for most U.S. stocks, Oct 21 (as of 3:01 p.m. ET) for 490 mostly large ones. Click a column heading to sort.
100 stocks
Download CSV| # | Company | Sector | Price | 1D | YTD | Market value | Avg daily $ volume | Price date |
|---|---|---|---|---|---|---|---|---|
| 1 | Silence TherapeuticsSLN | Health care | 19.57 | +125.5% | +222.0% | $2.8B | $75.2M | Oct 19 close |
| 2 | Disc Medicine, Inc.IRON | Health care | 78.36 | +37.9% | −1.3% | $3.0B | $65.8M | Oct 19 close |
| 3 | Nautilus Biotechnology, Inc.NAUT | Health care | 2.57 | +24.8% | +31.8% | $327.0M | $18.7M | Oct 19 close |
| 4 | Skydance CorporationSKYD | Communications | 7.82 | +14.9% | −41.6% | $8.4B | $311.3M | Oct 21, 3:01 p.m. ET |
| 5 | Annexon, Inc.ANNX | Health care | 3.87 | +13.5% | −22.9% | $577.9M | $13.0M | Oct 19 close |
| 6 | Arcutis Biotherapeutics, Inc.ARQT | Health care | 32.50 | +12.8% | +11.9% | $4.1B | $61.7M | Oct 19 close |
| 7 | Parabilis Medicines, Inc.PBLS | Health care | 25.39 | +11.6% | – | $3.1B | $28.4M | Oct 19 close |
| 8 | Veradermics, IncMANE | Health care | 121.14 | +11.3% | – | $5.1B | $109.3M | Oct 19 close |
| 9 | Axt IncAXTI | Technology | 57.05 | +10.8% | +248.9% | $3.7B | $594.2M | Oct 19 close |
| 10 | WiproWIT | Technology | 2.13 | +10.4% | −25.0% | $21.1B | $15.9M | Oct 21, 3:01 p.m. ET |
| 11 | United States Antimony CorpUAMY | Energy | 3.15 | +10.3% | −37.4% | $470.7M | $20.8M | Oct 19 close |
| 12 | Maze Therapeutics, Inc.MAZE | Health care | 30.36 | +10.3% | −26.7% | $1.7B | $26.6M | Oct 19 close |
| 13 | Prime Medicine, Inc.PRME | Health care | 3.82 | +10.1% | +10.1% | $692.9M | $17.4M | Oct 19 close |
| 14 | Agios PharmaceuticalsAGIO | Health care | 34.36 | +9.7% | +26.2% | $2.1B | $37.4M | Oct 19 close |
| 15 | Taysha Gene Therapies, Inc.TSHA | Health care | 3.96 | +9.2% | −28.1% | $1.3B | $20.3M | Oct 19 close |
| 16 | Monte Rosa TherapeuticsGLUE | Health care | 10.63 | +9.1% | −32.2% | $906.9M | $15.4M | Oct 19 close |
| 17 | SupermicroSMCI | Technology | 35.23 | +9.0% | +20.4% | $23.1B | $1.3B | Oct 21, 3:01 p.m. ET |
| 18 | Viridian Therapeutics, Inc.\DEVRDN | Health care | 20.72 | +8.9% | −33.4% | $2.3B | $41.0M | Oct 19 close |
| 19 | Applied Digital Corp.APLD | Technology | 19.64 | +8.8% | −19.9% | $5.9B | $567.4M | Oct 19 close |
| 20 | JFrog LtdFROG | – | 91.58 | +8.6% | +46.6% | $11.3B | $162.4M | Oct 19 close |
| 21 | Kopin CorporationKOPN | Technology | 3.56 | +8.4% | +52.4% | $662.6M | $14.8M | Oct 19 close |
| 22 | Lb Pharmaceuticals IncLBRX | Health care | 39.81 | +8.4% | +78.8% | $1.3B | $17.4M | Oct 19 close |
| 23 | MaxLinearMXL | Technology | 77.24 | +8.3% | +343.1% | $7.0B | $291.4M | Oct 19 close |
| 24 | Kestra Medical Technologies, LTD.KMTS | Health care | 29.45 | +8.1% | +11.1% | $1.8B | $8.9M | Oct 19 close |
| 25 | Kioxia Holdings CorporationKXIAY | – | 8.57 | +8.1% | +286.6% | $45.3B | $43.1M | Oct 19 close |
| 26 | Olema Pharmaceuticals, Inc.OLMA | Health care | 7.11 | +8.1% | −71.6% | $622.1M | $9.9M | Oct 19 close |
| 27 | Eikon Therapeutics, Inc.EIKN | Health care | 8.02 | +8.0% | – | $434.1M | $4.1M | Oct 19 close |
| 28 | Kodiak Sciences Inc.KOD | Health care | 92.59 | +8.0% | +231.2% | $5.8B | $345.4M | Oct 19 close |
| 29 | ManpowerGroup Inc.MAN | – | 44.44 | +8.0% | +49.5% | $2.1B | $56.0M | Oct 21, 3:01 p.m. ET |
| 30 | TOP Financial Group LtdTOP | Financials | 14.49 | +8.0% | +188.4% | $2.0B | $2.0M | Oct 19 close |
| 31 | Solid Biosciences Inc.SLDB | Health care | 5.97 | +8.0% | +5.8% | $640.1M | $9.5M | Oct 19 close |
| 32 | Nn IncNNBR | Materials | 3.68 | +7.9% | +187.5% | $303.9M | $13.3M | Oct 19 close |
| 33 | Friedman Industries IncFRD | Materials | 43.65 | +7.8% | +113.0% | $314.8M | $1.6M | Oct 19 close |
| 34 | Summit TherapeuticsSMMT | Health care | 15.77 | +7.8% | −9.9% | $12.6B | $113.6M | Oct 19 close |
| 35 | PowerFleetAIOT | Technology | 2.58 | +7.7% | −51.6% | $345.6M | $4.4M | Oct 19 close |
| 36 | Tango Therapeutics (United States)TNGX | Health care | 23.74 | +7.7% | +167.9% | $4.0B | $89.4M | Oct 19 close |
| 37 | Zenas BioPharma, Inc.ZBIO | Health care | 26.72 | +7.6% | −26.4% | $1.7B | $17.7M | Oct 19 close |
| 38 | Sturm, Ruger & Co.RGR | – | 46.63 | +7.5% | +42.8% | $745.1M | $20.3M | Oct 19 close |
| 39 | Celldex TherapeuticsCLDX | Health care | 29.55 | +7.3% | +8.8% | $2.3B | $75.2M | Oct 19 close |
| 40 | Praxis Precision Medicines, Inc.PRAX | Health care | 259.50 | +7.3% | −11.9% | $7.2B | $149.1M | Oct 19 close |
| 41 | United AirlinesUAL | Industrials | 102.21 | +7.3% | −8.6% | $33.2B | $473.5M | Oct 21, 3:01 p.m. ET |
| 42 | Entera Bio Ltd.ENTX | Health care | 2.88 | +7.3% | +48.2% | $497.8M | $1.8M | Oct 19 close |
| 43 | Warby ParkerWRBY | Consumer | 25.04 | +7.3% | +14.9% | $2.8B | $89.1M | Oct 19 close |
| 44 | SiTimeSITM | Technology | 506.05 | +7.2% | +43.3% | $15.2B | $281.8M | Oct 19 close |
| 45 | Western DigitalWDC | Technology | 376.42 | +7.2% | +118.5% | $135.7B | $3.7B | Oct 21, 3:01 p.m. ET |
| 46 | Aeglea BioTherapeuticsSYRE | Health care | 85.57 | +7.1% | +161.2% | $7.5B | $125.1M | Oct 19 close |
| 47 | Xeris Biopharma Holdings, Inc.XERS | Health care | 11.04 | +7.0% | +40.6% | $2.0B | $33.5M | Oct 19 close |
| 48 | Pharvaris N.V.PHVS | Health care | 29.67 | +7.0% | +6.9% | $2.2B | $21.3M | Oct 19 close |
| 49 | HighPeak Energy, Inc.HPK | Energy | 11.28 | +6.9% | +138.0% | $1.4B | $5.6M | Oct 19 close |
| 50 | Silgan HoldingsSLGN | Materials | 40.40 | +6.9% | +0.1% | $4.3B | $46.2M | Oct 19 close |
| 51 | Pulse Biosciences, INC.PLSE | Health care | 47.44 | +6.8% | +245.5% | $3.4B | $22.4M | Oct 19 close |
| 52 | EchoStarECHO | Communications | 92.47 | +6.7% | −14.9% | $27.0B | $357.3M | Oct 21, 3:01 p.m. ET |
| 53 | KyndrylKD | Technology | 14.29 | +6.6% | −46.2% | $3.1B | $50.4M | Oct 21, 3:01 p.m. ET |
| 54 | Silverback TherapeuticsSPRY | Health care | 4.29 | +6.6% | −63.2% | $426.1M | $6.1M | Oct 19 close |
| 55 | Galena BiopharmaSLS | Health care | 10.63 | +6.5% | +181.9% | $2.1B | $59.9M | Oct 19 close |
| 56 | Celsius Holdings, Inc.CELH | – | 30.01 | +6.5% | −34.4% | $7.6B | $157.1M | Oct 19 close |
| 57 | Power Solutions International, INC.PSIX | – | 49.04 | +6.5% | −14.2% | $1.1B | $18.8M | Oct 19 close |
| 58 | Odyssey Therapeutics, Inc.ODTX | Health care | 18.27 | +6.4% | – | $878.3M | $5.5M | Oct 19 close |
| 59 | Heartflow, Inc.HTFL | Health care | 51.35 | +6.3% | +76.2% | $4.5B | $77.1M | Oct 19 close |
| 60 | ArriVent BioPharma, Inc.AVBP | Health care | 17.70 | +6.2% | −12.1% | $872.5M | $38.1M | Oct 19 close |
| 61 | ACM Research, Inc.ACMR | Industrials | 56.38 | +6.2% | +42.9% | $3.9B | $97.3M | Oct 19 close |
| 62 | 3MMMM | Materials | 173.17 | +6.2% | +8.2% | $89.3B | $464.1M | Oct 21, 3:01 p.m. ET |
| 63 | RambusRMBS | Technology | 92.61 | +6.2% | +0.8% | $10.0B | $190.0M | Oct 19 close |
| 64 | WEBTOON Entertainment Inc.WBTN | Communications | 9.26 | +6.1% | −29.0% | $1.3B | $4.7M | Oct 19 close |
| 65 | BackblazeBLZE | Technology | 9.12 | +6.1% | +95.8% | $564.8M | $21.7M | Oct 19 close |
| 66 | DatadogDDOG | – | 262.15 | +6.1% | +92.8% | $99.3B | $766.7M | Oct 19 close |
| 67 | Pasqal Holding SAPSQL | Technology | 6.01 | +6.1% | – | $1.3B | $5.7M | Oct 19 close |
| 68 | TwilioTWLO | Technology | 259.19 | +6.1% | +82.2% | $39.8B | $1.4B | Oct 19 close |
| 69 | Dell TechnologiesDELL | Technology | 483.32 | +6.0% | +283.9% | $309.3B | $3.7B | Oct 21, 3:01 p.m. ET |
| 70 | Cohu IncCOHU | – | 53.85 | +6.0% | +131.4% | $2.5B | $67.7M | Oct 19 close |
| 71 | Forum Energy TechnologiesFET | Energy | 83.40 | +6.0% | +125.7% | $942.8M | $14.2M | Oct 19 close |
| 72 | Twist BioscienceTWST | Health care | 140.69 | +6.0% | +343.5% | $8.8B | $538.8M | Oct 19 close |
| 73 | América MóvilAMX | Communications | 24.14 | +6.0% | +16.8% | $72.0B | $62.2M | Oct 21, 3:01 p.m. ET |
| 74 | Immatics N.V.IMTX | Health care | 7.13 | +5.9% | −32.1% | $1.2B | $8.0M | Oct 19 close |
| 75 | Formfactor IncFORM | Technology | 111.23 | +5.9% | +99.4% | $8.7B | $275.4M | Oct 19 close |
| 76 | MBX Biosciences, Inc.MBX | Health care | 52.51 | +5.8% | +66.5% | $2.5B | $29.9M | Oct 19 close |
| 77 | Cullinan OncologyCGEM | Health care | 13.68 | +5.8% | +32.2% | $880.4M | $18.1M | Oct 19 close |
| 78 | NovoCure LtdNVCR | Health care | 14.88 | +5.8% | +15.1% | $1.7B | $21.0M | Oct 19 close |
| 79 | YD Bio LtdYDES | Health care | 6.26 | +5.7% | −48.6% | $404.4M | $2.3M | Oct 19 close |
| 80 | TTM TechnologiesTTMI | Technology | 99.24 | +5.7% | +43.8% | $10.5B | $311.6M | Oct 19 close |
| 81 | Indaptus Therapeutics, Inc.INDP | Health care | 2.78 | +5.7% | −4.5% | $370.4M | $1.6M | Oct 19 close |
| 82 | Concentrix CorpCNXC | – | 29.44 | +5.7% | −29.2% | $1.8B | $52.6M | Oct 21, 3:01 p.m. ET |
| 83 | Oshkosh CorporationOSK | Consumer | 134.84 | +5.7% | +7.3% | $8.4B | $94.1M | Oct 21, 3:01 p.m. ET |
| 84 | Anaptysbio, IncANAB | Health care | 49.24 | +5.6% | +52.4% | $1.4B | $27.5M | Oct 19 close |
| 85 | Savara IncSVRA | Health care | 4.70 | +5.6% | −22.1% | $965.7M | $12.7M | Oct 19 close |
| 86 | Chaince Digital Holdings Inc.CD | Financials | 7.31 | +5.5% | +47.1% | $804.1M | $2.0M | Oct 19 close |
| 87 | DXC TechnologyDXC | – | 15.20 | +5.5% | +3.7% | $2.4B | $53.9M | Oct 21, 3:01 p.m. ET |
| 88 | Alto Neuroscience, Inc.ANRO | Health care | 23.14 | +5.5% | +30.0% | $907.9M | $15.7M | Oct 19 close |
| 89 | AST SpaceMobileASTS | – | 42.88 | +5.5% | −41.0% | $16.0B | $871.9M | Oct 19 close |
| 90 | Design Therapeutics, Inc.DSGN | Health care | 10.87 | +5.4% | +15.9% | $680.3M | $6.4M | Oct 19 close |
| 91 | PDF SolutionsPDFS | Technology | 41.34 | +5.4% | +44.9% | $1.7B | $27.8M | Oct 19 close |
| 92 | Crescent Biopharma, INC.CBIO | Health care | 12.47 | +5.3% | +5.1% | $463.2M | $5.1M | Oct 19 close |
| 93 | ServiceNowNOW | Technology | 152.78 | +5.3% | −0.3% | $158.0B | $1.5B | Oct 21, 3:01 p.m. ET |
| 94 | DPC Holdings PLCDPC | – | 32.52 | +5.3% | – | $4.9B | $49.5M | Oct 19 close |
| 95 | TRex Bio, Inc.TRXB | Health care | 14.75 | +5.3% | – | $442.7M | $4.4M | Oct 19 close |
| 96 | Prokidney Corp.PROK | Health care | 1.40 | +5.3% | −37.5% | $588.8M | $2.0M | Oct 19 close |
| 97 | Aehr Test SystemsAEHR | – | 63.77 | +5.2% | +215.8% | $2.1B | $226.5M | Oct 19 close |
| 98 | RadwareRDWR | Technology | 28.58 | +5.2% | +18.6% | $1.3B | $9.9M | Oct 19 close |
| 99 | DynegyDYN | Energy | 14.99 | +5.2% | −23.4% | $3.0B | $49.3M | Oct 19 close |
| 100 | Brainsway Ltd.BWAY | Health care | 12.03 | +5.2% | +26.5% | $483.2M | $1.5M | Oct 19 close |
Prices: daily closing prices and 15-minute quotes collected by On the record from public market data; market values are the share count in each company’s latest SEC filing times the last price, or Yahoo Finance’s figure where the SEC count can’t be checked. Sectors come from each company’s industry in SEC EDGAR and Wikidata. Prices are for reference only.