Evening News Association

The Detroit News was founded by James E. Scripps, who, in turn, was the older half-brother and one-time partner of Edward W. Scripps. The paper's eventual success, however, is largely credited to Scripps' son-in-law, George Gough Booth, who came aboard at the request of his wife's father. Booth went on to construct Michigan's largest newspaper empire, founding the independent Booth Newspapers chain (now owned by S.I. Newhouse's Advance Publications) with his two brothers.

The Detroit News building was erected in 1917. It was designed by architect Albert Kahn, who included a faux-stone concrete building with large street-level arches to admit light. The arches along the east and south side of the building were bricked-in for protection after the 12th Street Riot in 1967. The bricked-in arches on the east and south ends of the building were reopened during renovations required when the Free Press relocated its offices there 20 years later.

In 1931, The Detroit News made history when it bought a three-place Pitcairn PCA-2 auto-gyro as a camera aircraft that could take off and land in restricted places and semi-hover for photos. It was the ancestor of today's well-known news helicopter. In 1935 a single Lockheed Model 9 Orion was purchased and modified by Lockheed as a news camera plane for The Detroit News. To work in that role, a pod was built into the frontal leading edge of the right-wing about eight feet (2.4 m) out from the fuselage. This pod had a glass dome on the front and a mounted camera. To aim the camera the pilot was provided with a primitive grid-like gun sight on his windshield.

Deb Price's column in The Detroit News, which debuted in 1992, was the first syndicated national column in American mainstream media that was specifically focused on gay life.

On July 13, 1995, Newspaper Guild employees of the Detroit Free Press and The News along with pressmen, printers and Teamsters, working for the "Detroit Newspapers" distribution arm, went on strike. Approximately half of the staffers crossed the picket line before the unions ended their strike in February 1997. The strike was resolved in court three years later, with the journalists' union losing its unfair labor practices case on appeal. Still, the weakened unions remain active at the paper, representing a majority of the employees under their jurisdiction.

On August 3, 2005, Gannett announced that it would sell The News to MediaNews Group and purchase the Free Press from the Knight Ridder company. With this move, Gannett became the managing partner in the papers' joint operating agreement. On May 7, 2006, the combined Sunday Detroit News and Free Press was replaced by a stand-alone Sunday Free Press. On December 16, 2008, Detroit Media Partnership announced a plan to limit weekday home delivery for both dailies to Thursday and Friday only. On other weekdays the paper sold at newsstands would be reduced to about 32 pages, and redesigned. This arrangement went into effect on March 30, 2009.

In February 2014, the DMP announced its offices along with those of The News and the Free Press would move from the West Lafayette building to six floors in both the old and new sections of the former Federal Reserve building at 160 West Fort Street. The partnership expected to place signs on the exterior similar to those on the former offices. The move took place October 24–27, 2014.

In December 2024, The Detroit News moved to the historic Albert Kahn-designed former Cadillac showroom at 6001 Cass Avenue, which was built in 1920.