Knome

2007 – Knome was co-founded by George M. Church based on the recognition that the rapidly falling price of whole genome sequencing would create substantial market need for whole genome interpretation technologies and services.

2008 – Knome interpreted the genome of the third named person to be sequenced—Dan Stoicescu (who followed James Watson and Craig Venter).

2009 – Knome launched kGAP, a cloud-based informatics engine.

2010 – Knome successfully assisted researchers at the University of British Columbia to identify the sixth known inherited gene defect causing Parkinson's disease.

2012 – Knome was selected as a technology partner by Johns Hopkins School of Medicine to analyze 1,000 genomes for asthma study.

2015 – Knome acquired by Tute Genomics (which later becomes a subsidiary of PierianDX in 2016).

Technology

Knome developed technologies that automated many of the manual tasks involved in interpreting whole human genomes. These technologies were designed to address the informatics and workflow bottlenecks that typically hinder whole genome interpretation. The company's core technology, kGAP, was developed in 2009 and served as the foundation for a number of Knome's products and services including the knoSYS® platform.

Products and services

For academic, pharmaceutical, and medical researchers, Knome offered:

knoSYS® Platform

Provides labs with a scalable, production-grade informatics system for the analysis, annotation, and interpretation of human next-gen sequence data (genome, exome, targeted gene).