Overview
- TickerTLSA on Nasdaq2
- IndustryPharmaceutical Preparations2
- HeadquartersHamilton, Bermuda2
- Incorporated inBermuda3
- Business address3Rd Floor, 11-12 St. James'S Square, London, England, X0 Sw1Y 4Lb3
- Filer categoryNon-accelerated filer3
- Legal formExempted Companies Limited by Shares2
- LEI984500769407C5E46F422
- StatusActive2
- LEI statusIssued and current2
- Registered addressRichmond House, 12 Par-la-Ville Road, HM 08 Hamilton, Bermuda2
- Registered withRegistrar of Companies (Ministry of Economic Development), 554082
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Tiziana Life Sciences plc), Tiziana Therapeutics Inc., Tiziana Pharma Limited and Longevia Genomics S.r.l.4 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Financial statements
No quarterly figures reported.
Every line of the income statement as filed: the last 3 fiscal years, latest first.10
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Research and Development | -$10.3M | -$5.2M | -$8.1M |
| Operating expenses | -$10.9M | -$10.6M | -$9.9M |
| Total operating expenses | -$21.1M | -$15.8M | -$18.0M |
| Loss from operations | -$21.1M | -$15.8M | -$18.0M |
| Finance income | $1.0K | $814.0K | $1.1M |
| FV Gain/(Loss) on Investment | $2.3M | -$1.8M | -$402.0K |
| Gain/on sale of Investment | $367.0K | ||
| Total other income/(expense) | $2.7M | -$952.0K | $742.0K |
| Loss from operations before income taxes | -$18.4M | -$16.7M | -$17.2M |
| Income tax credit/(expense) | $4.9M | -$449.0K | |
| Loss for the year | -$18.4M | -$11.9M | -$17.7M |
| Gain/(Loss) on currency translation | -$88.0K | -$72.0K | $1.5M |
| Comprehensive loss | -$18.5M | -$11.9M | -$16.2M |
| Basic loss per share attributable to common shareholders (in Dollars per share) | -$0.16 | -$0.11 | -$0.17 |
| Diluted loss per share attributable to common shareholders (in Dollars per share) | -$0.16 | -$0.11 | -$0.17 |
No quarter-by-quarter statement was filed.
No quarterly figures reported.
Every line of the balance sheet as filed: the last 4 fiscal years (annual) or 4 quarters (quarterly), latest first.10
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Cash and cash equivalents | $4.0M | $3.7M | $1.2M | $18.1M |
| Prepayments and other receivables | $459.0K | $145.0K | ||
| Taxation receivable | $99.0K | $32.0K | ||
| Related party receivables | $4.0M | $3.6M | ||
| Total current assets | $8.6M | $7.5M | ||
| Property and equipment, net | $26.0K | $16.0K | ||
| Right of use asset | $473.0K | $171.0K | ||
| Investment in related party | $2.4M | $3.6M | ||
| Total non-current assets | $2.9M | $3.8M | ||
| Total assets | $11.5M | $11.3M | ||
| Accounts payable and accrued expenses | $10.5M | $7.2M | ||
| Deferred Income | $530.0K | |||
| Lease Liability | $222.0K | $106.0K | ||
| Other liabilities | -$3.0K | $12.0K | ||
| Total current liabilities | $11.2M | $7.3M | ||
| Lease Liability (Non-Current) | $234.0K | |||
| Total liabilities | $11.4M | $7.3M | ||
| Called up share capital (120,507,401 shares are issued and outstanding; 2024:111,462,617) | $121.0K | $111.0K | ||
| Share premium | $34.7M | $23.1M | ||
| Share based payment reserve Options | $8.5M | $7.6M | ||
| Share based payment reserve warrants | $69.0K | $25.0K | ||
| Merger relief reserve | $118.7M | $118.7M | ||
| RSU reserve | $2.9M | $910.0K | ||
| Translation reserve | -$1.8M | -$1.7M | ||
| Retained earnings | -$163.1M | -$144.8M | ||
| Total shareholders equity | $52.0K | $3.9M | $5.5M | $19.6M |
| Total liabilities and shareholders equity | $11.5M | $11.3M | ||
| Share capital, issued (in Shares) | 120.5M shares | 111.5M shares | ||
| Share capital, outstanding (in Shares) | 120.5M shares | 111.5M shares |
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Cash and cash equivalents | $4.0M | $3.7M | $1.2M | $18.1M |
| Prepayments and other receivables | $459.0K | $145.0K | ||
| Taxation receivable | $99.0K | $32.0K | ||
| Related party receivables | $4.0M | $3.6M | ||
| Total current assets | $8.6M | $7.5M | ||
| Property and equipment, net | $26.0K | $16.0K | ||
| Right of use asset | $473.0K | $171.0K | ||
| Investment in related party | $2.4M | $3.6M | ||
| Total non-current assets | $2.9M | $3.8M | ||
| Total assets | $11.5M | $11.3M | ||
| Accounts payable and accrued expenses | $10.5M | $7.2M | ||
| Deferred Income | $530.0K | |||
| Lease Liability | $222.0K | $106.0K | ||
| Other liabilities | -$3.0K | $12.0K | ||
| Total current liabilities | $11.2M | $7.3M | ||
| Lease Liability (Non-Current) | $234.0K | |||
| Total liabilities | $11.4M | $7.3M | ||
| Called up share capital (120,507,401 shares are issued and outstanding; 2024:111,462,617) | $121.0K | $111.0K | ||
| Share premium | $34.7M | $23.1M | ||
| Share based payment reserve Options | $8.5M | $7.6M | ||
| Share based payment reserve warrants | $69.0K | $25.0K | ||
| Merger relief reserve | $118.7M | $118.7M | ||
| RSU reserve | $2.9M | $910.0K | ||
| Translation reserve | -$1.8M | -$1.7M | ||
| Retained earnings | -$163.1M | -$144.8M | ||
| Total shareholders equity | $52.0K | $3.9M | $5.5M | $19.6M |
| Total liabilities and shareholders equity | $11.5M | $11.3M | ||
| Share capital, issued (in Shares) | 120.5M shares | 111.5M shares | ||
| Share capital, outstanding (in Shares) | 120.5M shares | 111.5M shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 3 fiscal years, latest first.10
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Loss from operations before income taxes | -$18.4M | -$16.7M | -$17.2M |
| Shares issued in lieu of directors fees, bonus and expenses | $1.3M | $1.6M | $525.0K |
| Shares issued in lieu of consultancy fees | $1.8M | ||
| Share based payment restricted stock | $1.9M | $910.0K | |
| Share based payment options | $1.2M | $1.7M | $1.8M |
| Options forfeited during the year | -$109.0K | -$227.0K | -$39.0K |
| Fair value (Gain)/loss on investment, net | -$1.8M | $1.8M | $402.0K |
| Write back of bad debt | -$166.0K | ||
| (Gain)/loss on disposal of assets | $1.0K | ||
| Depreciation | $12.0K | $12.0K | $7.0K |
| (Gain)/ loss on foreign exchange | -$152.0K | $158.0K | $1.5M |
| Depreciation of right-of-use asset | $222.0K | $112.0K | $89.0K |
| Cash (outflow)/inflow from taxation | -$75.0K | $8.8M | |
| Interest on related party loan conversion | -$795.0K | -$1.1M | |
| Net (increase) in related party receivables | -$378.0K | -$1.5M | -$1.5M |
| Net (increase)/decrease in operating assets/other receivables | -$314.0K | $78.0K | $80.0K |
| Net increase/(decrease) in operating liabilities /other liabilities | $3.2M | $839.0K | -$138.0K |
| Net increase/(decrease) in deferred revenue | $530.0K | ||
| Net cash used in operating activities | -$12.8M | -$1.5M | -$15.7M |
| Purchase of Fixed Assets | -$21.0K | -$19.0K | |
| Investment in Related Party | -$1.0M | ||
| Sale of Okyo Shares | $3.1M | ||
| Purchase of Treasury Shares | -$52.0K | -$253.0K | |
| Net cash used in Investing activities | $3.0M | -$71.0K | -$1.3M |
| Proceeds from issuance of ordinary shares ATM, net | $10.1M | $124.0K | $24.0K |
| Proceeds from issuance of ordinary shares Fundraise, net | $4.4M | ||
| Proceeds from the issuance of warrants | $48.0K | $135.0K | |
| Repayment of leasing liabilities | -$196.0K | -$141.0K | -$119.0K |
| Proceeds of Exercise of options | $95.0K | $75.0K | |
| Net cash (used in)/provided by financing activities | $10.0M | $4.5M | $40.0K |
| Net increase/(decrease) in cash and cash equivalents | $202.0K | $2.9M | -$16.9M |
| Exchange difference on cash and cash equivalents | $84.0K | -$367.0K | -$28.0K |
No quarter-by-quarter statement was filed.
Corporate structure
Tiziana Life Sciences Ltd sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.
Major holders of Tiziana Life Sciences Ltd
- Jorey Chernett Filed SCHEDULE 13G/A on Tiziana Life Sciences Ltd, latest Dec 10, 2025 (3 filings since Jun 12, 2025)
- Laura Natalia Monica Fonda Filed SCHEDULE 13G on Tiziana Life Sciences Ltd, latest Oct 28, 2025 (2 filings since May 4, 2022)
- Gabriele M. Cerrone Filed SC 13D on Tiziana Life Sciences Ltd, latest Jan 4, 2022
- Tiziana Life Sciences Ltd Hamilton, Bermuda
Built from parent and subsidiary links from GLEIF, the Global Legal Entity Identifier Foundation (CC0); major holders from Schedules 13D and 13G. Each entity in the chart links to its source.
What it owns
What Tiziana Life Sciences Ltd reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.
Property and equipment
| Item | Latest | A year before | Change |
|---|---|---|---|
| Property and equipment, net | $16.0K9 Dec 31, 2024 | $10.0K9 Dec 31, 2023 | +60.0% |
| Operating-lease assets (leased space) | $171.0K9 Dec 31, 2024 | $283.0K9 Dec 31, 2023 | −39.6% |
Investments
Leadership
Who has led Tiziana Life Sciences Ltd, and when. Pick a name to see everywhere that person has worked.
Chief executive
- Chief executive officerIvor Elrifi Jul 23, 2026 to now12
Board members and other officers (1)
- Board memberIvor Elrifi Jul 23, 2026 to now12
Former names
- Tiziana Life Sciences plcNov 30, 2017 to Oct 21, 20213
Timeline
Calendar
Drug trials and FDA: coming up
- Apr 1, 2027Phase 2 trial readout expected Phase 2 trial of Foralumab Nasal in Multiple System Atrophy: primary completion expected Apr 1, 2027 (ClinicalTrials.gov NCT06868628).13
- Jul 2027Phase 2 trial readout expected Phase 2 trial of Foralumab Nasal in ALS (Amyotrophic Lateral Sclerosis): primary completion expected Jul 2027 (ClinicalTrials.gov NCT07688239).14
Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). Trials from ClinicalTrials.gov, as the sponsor registered them (expected dates are the sponsor's own and often move); approvals and advisory committee meetings from the FDA. The FDA does not publish its decision (PDUFA) dates. The full markets calendar
Filings
245 filings to the SEC since October 2021: 7 annual reports, 1 major events, 10 insider forms, 6 large holders, 221 other. The latest 20:
- Sep 30, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Sep 29, 20264 EDGAR
- Sep 28, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Sep 21, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Sep 17, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Aug 24, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Aug 7, 20264/A EDGAR
- Aug 7, 20264/A EDGAR
- Aug 6, 20264 EDGAR
- Aug 6, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Aug 5, 20264 EDGAR
- Aug 4, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Jul 31, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Jul 23, 20263 EDGAR
- Jul 23, 20264 EDGAR
- Jul 22, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Jun 25, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- Jun 17, 20264 EDGAR
- Jun 15, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
- May 28, 20266-K REPORT OF FOREIGN PRIVATE ISSUER EDGAR
The 245 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
5 open-market trades by officers, directors and large owners since October 2021: 5 buys and 0 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Aug 5, 2026 | Elrifi IvorChief Executive Officer | Buy | 237,616 | $1.00 | $237.6K | Form 4 |
| Aug 4, 2026 | Elrifi IvorChief Executive Officer | Buy | 83,807 | $0.97 | $81.3K | Form 4 |
| Aug 3, 2026 | Elrifi IvorChief Executive Officer | Buy | 667,000 | $1.00 | $667.0K | Form 4 |
| Jul 21, 2026 | CERRONE GABRIELE MDirector | Buy | 42,357 | $0.99 | $41.9K | Form 4 |
| Jun 12, 2026 | CERRONE GABRIELE MDirector | Buy | 15,000 | $1.11 | $16.6K | Form 4 |
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
SEC filer profile
How Tiziana Life Sciences Ltd is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.
- Name on EDGARTiziana Life Sciences Ltd1
- CIK0001723069
- Filer statusNon-accelerated filer not an emerging growth company; not a shell company4
- Incorporated inBermuda4
- Fiscal year endsDecember 311
- Industry code (SIC)2834 Pharmaceutical Preparations1
- SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
- Business address3Rd Floor, 11-12 St. James'S Square, London, England, X0 SW1Y 4LB1
- Phone0044(0) 207-495-23791
- Shares outstanding120,507,401 shares as of Dec 31, 20254
- AuditorPKF Littlejohn LLP, London, England PCAOB ID 2814; no auditor attestation of internal control over financial reporting4
- On EDGAR sinceNov 30, 20171
- Filings486 in all: 6-K (346), CORRESP (21), UPLOAD (12), 424B5 (10), 20-F (8), DRS/A (7), F-1/A (7), DRS (6)1
All 38 form types
EFFECT (6), FWP (6), NT 20-F (6), 4 (5), DRSLTR (4), 3 (3), F-3 (3), F-3/A (3), F-6 POS (3), SC 13G (3), 20-F/A (2), 4/A (2), F-1 (2), POS AM (2), SC 13G/A (2), SCHEDULE 13G (2), SCHEDULE 13G/A (2), 25-NSE (1), 424B4 (1), 6-K/A (1), 8-A12B (1), 8-K12B (1), AW (1), CERT (1), F-6 (1), F-6/A (1), F-6EF (1), RW (1), S-8 (1), SC 13D (1)
- Latest filingsAnnual report (20-F) May 1, 2026
Securities registered for trading
| Class | Symbol | Exchange |
|---|---|---|
| Common Shares | TLSA | NASDAQ |
From the cover page of the 20-F filed May 1, 2026 (Section 12(b) of the Exchange Act).4
Sources
The numbers on this page point here. Each one links to the record it came from.
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- 12SEC EDGARIvor Elrifi, Chief executive officer
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