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Funds · 13F filer · St Peter Port, Guernsey, X0

Syncona Portfolio Ltd

$26.6M in 1 U.S. stocks and ETFs at the end of June 30, 2026, as reported to the SEC.1

1y return−23.4%S&P 500 +20.9%

These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.

$100 invested in its stock picks

Since December 31, 2023: $39 against $157 in the S&P 500.2

Syncona Portfolio LtdS&P 500 (SPY)
$34$100$15720232026

Top holdings

At the end of June 30, 2026. Change is in shares since the quarter before.2

StockValueShare of portfolioChange
AUTLAutolus Therapeutics PLC$26.6M100.0%

Best picks still held

How each current holding has done since the quarter it first appeared in its filings (up to six years back).

StockHeld sinceReturn sinceNow worth
AUTLAutolus Therapeutics PLCDecember 31, 2021−69.2%$26.6M

Sold off last quarter

  • IPSCCentury Therapeutics was $2.7M

Quarter by quarter

QuarterIts picksS&P 500
June 30, 2026+15.1%+14.8%
March 31, 2026−25.1%−4.6%
December 31, 2025+23.8%+2.4%
September 30, 2025−28.2%+7.8%
June 30, 2025+46.4%+10.5%
March 31, 2025−19.2%−4.6%
December 31, 2024−28.8%+2.1%
September 30, 2024+5.4%+5.4%
June 30, 2024−44.5%+4.0%
March 31, 2024+2.6%+10.0%
September 30, 2023−2.7%−3.6%
June 30, 2023+21.7%+8.3%
March 31, 2023−2.5%+7.0%
December 31, 2022−36.8%+7.1%
September 30, 2022−17.9%−5.3%
June 30, 2022−22.6%−16.5%
March 31, 2022−30.6%−4.9%

Sources

Every number on this page points here. Each one links to the public record.

  1. 1
    CIK 1725042
  2. 2
    Filed August 7, 2026 · accession 0001193125-26-338587