Cormorant Asset Management, LP: investment adviser

Cormorant’s business is also conducted through its affiliates, organized as Delaware limited liability companies, Cormorant Asset Management GP, LLC, Cormorant Global Healthcare GP, LLC, Cormorant Private Healthcare GP, LLC, Cormorant Private Healthcare GP II, LLC, Cormorant Private Healthcare GP III, LLC, Cormorant Private Healthcare GP IV, LLC, Cormorant Private Healthcare GP V, LLC, and Cormorant Private Healthcare GP VI, LLC (each the “General Partner” and, collectively, the “General Partners”) and Cormorant PR (as described further below). Bihua Chen fully controls Cormorant. Ms. Chen is the sole managing member of the General Partners and Cormorant PR. Cormorant has delegated a part of its advisory services to Cormorant Asset Management Puerto Rico LLC (“Cormorant PR”), which is organized under the laws of Puerto Rico. Ms. Chen fully owns and controls Cormorant PR. Cormorant PR is charged with providing discretionary investment advisory services to the Advisory Clients’ (as described further below) portfolios. Types of Advisory Services Cormorant provides discretionary investment advisory services to the following advisory clients (the “Advisory Clients”): •

Hedge Fund: Cormorant Global Healthcare Master Fund, LP, a Cayman Island exempted limited partnership, is the main fund in a master-feeder hedge fund (the “Hedge Fund”) with Cormorant Global Healthcare Fund, LP, a Delaware limited partnership, as the onshore feeder (the “Onshore Feeder”) and Cormorant Global Healthcare Offshore Fund, Ltd., a Cayman Island exempted limited company, as the offshore feeder (the “Offshore Feeder”).

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Private Equity Funds: o Cormorant Private Healthcare Fund I, LP, a Delaware limited partnership, is a private equity fund (the “PE Fund”), organized via a mini master-feeder structure with Cormorant Private Healthcare Offshore Fund I LP, a Cayman Island exempted limited partnership, as the offshore feeder; o Cormorant Private Healthcare Fund II, LP, a Delaware limited partnership, is a private equity fund (the “PE Fund II”), organized via a mini master-feeder structure with Cormorant Private Healthcare Offshore Fund II LP, a Cayman Island exempted limited partnership, as the offshore feeder; o Cormorant Private Healthcare Fund III, LP, a Delaware limited partnership, is a private equity fund (the “PE Fund III”), organized via a mini master-feeder structure with Cormorant Private Healthcare Offshore Fund III LP, a Cayman Island exempted limited partnership, as the offshore feeder; o Cormorant Private Healthcare Fund IV, LP, a Delaware limited partnership, is a private equity fund (the “PE Fund IV”), organized via a mini master-feeder structure with Cormorant Private Healthcare Offshore Fund IV LP, a Cayman Island exempted limited

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partnership, as the offshore feeder; Cormorant Private Healthcare Fund V, LP, a Delaware limited partnership, is a private equity fund (the “PE Fund V”), organized via a mini master-feeder structure with Cormorant Private Healthcare Offshore Fund V LP, a Cayman Island exempted limited partnership, as the offshore feeder; and Cormorant Private Healthcare Fund VI, LP, a Delaware limited partnership, is a private equity fund (the “PE Fund VI”), organized via a mini master-feeder structure with Cormorant Private Healthcare Offshore Fund VI LP, a Cayman Island exempted limited partnership, as the offshore feeder.

Separately Managed Account: a single separately managed account (the “Account”).

Unless specifically noted otherwise, in this Brochure, the Hedge Fund, the PE Fund, the PE Fund II, the PE Fund III, the PE Fund IV, the PE Fund V, and the PE Fund VI are each referred to as a “Fund” and collectively as the “Funds.” In the Brochure sections discussing our private equity funds, we will refer to the PE Fund, the PE Fund II, the PE Fund III, the PE Fund IV, the PE Fund V, and the PE Fund VI as the “PE Funds.” The Hedge Fund’s objective is to seek superior risk-adjusted returns with low market correlation. Cormorant aims to accomplish this objective primarily through a combination of long investment positions and short selling in order to achieve capital appreciation, while attempting to preserve capital and mitigate risk through hedging activities. The Hedge Fund invests substantially, but not solely, in publicly traded equity securities in the healthcare and life science industries. Cormorant provides discretionary investment advisory services to the Account in accordance with the same objective and similar parameters as the Hedge Fund. The PE Funds’ objective is to generate significant long-term capital appreciation by creating or investing in market innovative companies in the biotechnology and life sciences marketplace (each a “Portfolio Company” and, collectively, the “Portfolio Companies”). Cormorant expects to achieve this objective by primarily investing in privately held early stage, later stage developmental, and “crossover” (or mezzanine) round or pre-IPO Portfolio Companies in the biotech, medical device, diagnostics, generics, pharmaceutical, specialty pharmaceutical, and life science research tool sectors. Additionally, the Hedge Fund and the PE Funds may invest in Portfolio Companies through PIPEs (i.e., private investment in public equity), start-up Portfolio Companies, and/or special purpose acquisition companies (i.e., “SPACs”), including start-ups organized, managed, and funded with Cormorant’s or its affiliates’ proprietary capital. Tailored Relationships Cormorant does not tailor its advisory services to the individual needs of investors in the Advisory Clients (each an “Investor” and, collectively, the “Investors”) and does not accept Investor imposed investment restrictions. Investors are informed of Cormorant’s investment strategy for an Advisory Client prior to making their investment. When deemed appropriate, Cormorant has established, and may in the future establish, separately managed accounts for particular investors. These accounts are subject to investment objectives, guidelines, restrictions, fee arrangements, and other individually negotiated terms. Generally, these account relationships involve significant account minimums.

Wrap Fee Programs Cormorant does not participate in any wrap fee programs. Assets Under Discretionary and Non-Discretionary Management As of December 31, 2025, Cormorant had approximately $ 3,838,575,938 in regulatory assets under management, all on a discretionary basis.

The General Partner is entitled to receive an annual performance allocation equal to 20.0% of the net appreciation in the value of each Investor’s Series A capital account and 17.5% of the net appreciation in the value of each Investor’s Series F capital account, which are both subject to a customary high-water mark. Series F was available to Investors at the Hedge Fund’s launch and is currently closed. With respect to the PE Funds, Cormorant receives a quarterly management fee at the beginning of each calendar quarter in an amount equal to 0.25% (1.0% annualized) or 0.50% (2.0% annualized) of the sum of (i) the aggregate net capital contributions of each Investor in the fund attributable to the cost of investments in Portfolio Companies that have not yet made an initial public offering and (ii) the capital account balance of such Investor attributable to each Portfolio Company that has made an initial public offering, payable until the end of each of the Fund's Term, as defined in each of the Funds’ offering and governing documents. In addition, the General Partner may receive carried interest distributions (the “Carried Interest Distributions”), based on, among other factors, return of paid-in capital contributions, proceeds received by the Fund and the preferred return and subject to a clawback provision. The Carried Interest Distributions are generally deducted from proceeds distributed by the PE Funds from time to time (including upon the liquidation of the Fund) as determined by its General Partner. Additionally, PE Fund III offered limited parentship interests with 1% management fee and 30% carried interest that was calculated in the same manner noted above. The management fee, performance allocation, and Carried Interest Distributions may, in the sole discretion of Cormorant or the General Partners (as applicable), be waived, reduced, or rebated for certain Investors, including affiliates of the General Partners or Cormorant. Cormorant also receives from the Account an asset-based monthly management fee and an annual performance-based fee, subject to a customary high-water mark, in the amounts set forth in the agreement between Cormorant and the Account investor. Cormorant will reduce the management fee by 100% of (i) the Funds’ share of directors’ fees paid by Portfolio Companies to Cormorant or its affiliates and their respective managers, members, or employees directly attributable to the Funds’ investment in such Portfolio Companies and (ii) all net fee income

received by Cormorant, its affiliates, and their members or employees (not otherwise employed by or engaged as a consultant or other service provider by a Portfolio Company) from Portfolio Companies directly attributable to the Funds’ investment in such Portfolio Companies. Investors invested in the Advisory Clients do not have the ability to choose to be billed directly for fees incurred. Cormorant (or an affiliate) deducts fees from Investor assets invested in the Advisory Clients. Cormorant shares a portion of the management fees with Cormorant PR in exchange for the advisory services Cormorant PR provides to the Advisory Clients. Other Fees and Expenses In connection with the investment management services it provides, Cormorant will bear all of its own normal and recurring operating expenses and overhead costs, except that research and research-related expenses may be paid for through the permitted use of “soft dollars” (as described in Item 12 - Brokerage Practices). The management fee may exceed the expenses borne by Cormorant on behalf of its Advisory Clients. In addition to fees payable to Cormorant, the Advisory Clients, and therefore their respective Investors, may pay a variety of expenses related to each Advisory Client’s investments and operations, including, without limitation, brokerage and other transaction costs, clearing and settlement charges, trade break fees, consulting expenses, research expenses (including research-related travel expenses), legal fees and other expenses in connection with conducting due diligence and negotiating the terms of certain investments, custodial fees, initial and variation margin, interest and commitment fees on debit balances or borrowings, stock borrowing fees and proxy solicitation expenses, legal expenses, audit and tax preparation expenses, accounting fees, costs of the administration of the Advisory Clients (including, but not limited to, fees and expenses of an administrator and third party valuation services), regulatory costs and expenses (including filing and licensing fees), organizational expenses, premiums for liability insurance, fees for risk management services, indemnification expenses, entity-level taxes, issue or transfer taxes, costs of reporting to Investors, costs of litigation, any extraordinary expenses, and other similar expenses related to the Advisory Clients. Certain Advisory Clients, including the PE Funds, will also bear expenses related to the purchase, sale, recapitalization, or refinancing of Portfolio Companies (including broken deal expenses), placement agent fees, legal fees, and other expenses in connection with conducting due diligence and negotiating the terms of investments in Portfolio Companies.

Cormorant has addressed this conflict by adopting and following a trade allocation policy that no allocation decisions may be based on the fees or allocations paid by a particular Advisory Client. Cormorant’s policy on addressing potential portfolio trading conflicts is addressed in Item 12, “Trade Aggregation and Allocation.” All Investors are provided with clear disclosure as to how performance-based compensation

is charged with respect to a particular Advisory Client and the risks associated with such performancebased compensation prior to making an investment. Cormorant is required to act in a manner that it considers fair, reasonable, and equitable in allocating investment opportunities to the Advisory Clients. Cormorant and its affiliates, however, are not otherwise subject to any specific obligations or requirements concerning the allocation of time, effort or investment opportunities, or any restrictions on the nature or timing of investments for the Advisory Clients. Cormorant recognizes that it is a fiduciary and as such must act in the Advisory Clients’ best interests.

investors in the Offshore Feeder must also be “accredited investors” and “qualified purchasers.” Shares in the Offshore Feeder are typically offered to eligible investors that are not U.S. persons or U.S. tax-exempt entities. The minimum capital commitment for an Investor in the PE Funds is $5,000,000. The General Partner, in its discretion, reserves the right to reject or accept only a portion of the capital commitment of any prospective Investor. Capital commitments of lesser amounts may be accepted at the General Partner’s discretion. The interests are being offered only to investors that are “accredited investors” and “qualified purchasers.” The General Partner may admit certain friends and family as Investors on terms that are more preferential than those that are generally available to Investors. The Account was established for a sophisticated institutional investor and involves a significant minimum investment.

through hedging activities. Most of the Hedge Fund’s assets are invested on a global basis in publicly traded equity securities in the healthcare and life science industries. The PE Funds’ objective is to generate significant long-term capital appreciation by creating or investing in market innovative companies in the biotechnology and life sciences marketplace. Cormorant intends to achieve this objective by primarily investing in privately held early stage, later stage developmental, and “crossover” (or mezzanine) round or pre-IPO biotech and life sciences companies. Cormorant expects to hold its investments in Portfolio Companies until after a successful IPO of such Portfolio Company’s shares or in connection with an acquisition of such Portfolio Company by another company. The life science industry has and will continue to play a major role in our society and economy. Due to its importance to the economy as well as the difficulty of assessing scientific, technological, and clinical assets, Cormorant believes that there are significant market inefficiencies, and therefore opportunities for superior risk-adjusted return, in the life sciences industry. Additionally, Cormorant has a long-term investment horizon and believes this to be a differentiating feature of its investment philosophy. Cormorant believes that the most attractive investment opportunities are those where Cormorant has a differentiated view on the business and financial outlook of a potential investment, with clearly defined stock drivers or catalysts. Investment Process Cormorant uses a fundamental, research-intensive approach that focuses primarily on scientific research to identify investment opportunities. The identification process is based on Cormorant’s research and understanding of drugs and technologies developed by both private and public biotechnology and life sciences companies. After identifying potential investments, Cormorant will conduct therapeutic area reviews and research of such companies. The purpose of this research is to understand a company’s products, business model, strategy, marketplace, competition, and ultimately to identify key variables in a potential investment. Cormorant also intends to maintain an analytical “edge” in understanding those variables by bringing an independent perspective on the business and financial outlook of such potential investments developed through a detailed fundamental analysis utilizing such research. Typically, Cormorant will invest in companies where its outlook is meaningfully different than market consensus. In carrying out the Hedge Fund’s investment objectives, Cormorant focuses on long and short positions that Cormorant has a reasonable expectation will produce positive returns. The long positions typically include securities that Cormorant believes are undervalued or that Cormorant believes will increase in value. The short positions typically include securities that Cormorant believes are overvalued or that Cormorant believes will decrease in value. Additionally, Cormorant may engage in long or short trading strategies to generate profits from irrational market behavior or short-term valuation anomalies. Further, particularly on the long side, Cormorant tends to concentrate investments in the ideas that Cormorant holds the highest convictions. Consequently, the Hedge fund may invest a significant portion of its assets in securities of a limited number of issuers. Consistent with the investment philosophy, the Hedge Fund is not constrained by diversification requirements or other limitations as to the types of securities, other investment instruments, industries, sectors, countries, or asset classes in which it may be invested. The Hedge Fund invests in companies both within and outside the U.S., with U.S. opportunities likely comprising a majority of the portfolio. In carrying out the PE Funds’ investment objectives, Cormorant focuses on investments that Cormorant has a reasonable expectation will produce significant returns. Cormorant invests each of the PE Fund’s assets in a select number of Portfolio Companies and intends to hold its investments in Portfolio Companies until after a successful IPO of such Portfolio Company’s shares or in connection with an acquisition of such

Portfolio Company by another company. In the event of and following the IPO of a Portfolio Company, each PE Fund will hold the shares of such Portfolio Company for such period of time as may be determined by Cormorant in its sole discretion. Cormorant may invest in Portfolio Companies both within and outside the U.S., with U.S. investments expected to comprise a majority of the portfolio. Cormorant, when it deems appropriate, may use leverage in its investment program. Cormorant expects that the PE Fund, the PE Fund II, the PE Fund III, the PE Fund IV, the PE Fund V, the PE Fund VI, and the Hedge Fund will each seek to participate in the initial public offering (if any) of the shares of one or more of the Portfolio Companies, even if the Hedge Fund was not invested in the applicable Portfolio Company prior to the initial public offering of such Portfolio Company’s shares. In most cases, the opportunity to purchase shares of a Portfolio Company that are available as a part of such Portfolio Company’s initial public offering shall be made in accordance with Cormorant’s allocation policies and take into account each of the Fund’s investment objectives, investment portfolio, available cash, the investment restrictions set forth in their respective governing agreements, and/or any legal, tax, or other regulatory restrictions that may be applicable to the Funds or the applicable Portfolio Company. Risk of Loss Risks Associated with the Investments Generally Investment and Trading Risks. An investment in the Funds involves a high degree of risk, including the risk that the entire amount invested may be lost. No guarantee or representation is made that Cormorant’s investment program will be successful. Cormorant invests substantially all of the Funds’ assets in securities, some of which may be particularly sensitive to economic, market, industry, and other variable conditions. In recent years, the markets in which Cormorant invests have experienced significant volatility and losses. No assurance can be given as to when or whether adverse events might occur that could cause immediate and significant losses to the Funds. Therefore, an Investor should only invest in the Funds if it can withstand a total loss of its investment. Risks Associated with the Life Sciences, Biotechnology, and Healthcare Industry. Companies in the life science, biotechnology, and healthcare industry are subject to certain risks not typical of investments made in other industries, including the following: •

The financial performance of many healthcare companies is highly dependent on third-party and government reimbursement policies that are under constant review and are subject to change at any time. Any such change could adversely affect the viability of one or more such companies.

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New legislative and regulatory initiatives by state and federal legislative bodies or the Food and Drug Administration (“FDA”) could impede, rather than promote, the growth of the healthcare industry. In the event of such an impediment, Cormorant may have difficulty identifying attractive healthcare investment opportunities. Moreover, otherwise profitable investments could become unprofitable.

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Many healthcare companies derive a large portion or all of their value from a single product. The viability of these products and financial performance of these companies is highly dependent on completing successful clinical trials, obtaining FDA approval, and receiving third-party reimbursement.

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Many life science companies face high research and development costs and obsolescence of their

products. These factors may have a significant adverse effect on the financial condition and operating results of these companies. •

Many life sciences and healthcare companies depend heavily upon intellectual property for their competitive position. There can be no assurance that the companies will be able to obtain patents for key inventions. Moreover, within the life sciences and healthcare industries, patent challenges are frequent. Even if patents held by the company are upheld, any challenges thereto may be costly and distracting to the company’s management.

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As the Funds invest primarily in securities of healthcare companies, its investment performance will be closely tied to and affected by the healthcare industry. Healthcare companies often face the same obstacles, issues, or regulatory burdens, and their securities may react similarly and move in unison to these or other market conditions. The growth of the healthcare industry is highly impacted by the current and future state and federal legislative and regulatory climates.

Concentration of Investments. From time to time, the Funds’ portfolios could be concentrated in a particular type of security, industry or industry segment, geographic location, or market capitalization. This may be the result of the Funds’ opportunistic investing, external market forces, or the lack of liquidity in one security as compared to other securities the Funds hold. Losses incurred in a position making up a significant percentage of the Funds’ capital could have a material adverse effect on the Funds’ overall financial condition. This limited diversity could expose the Funds to significantly greater volatility than in a more diversified portfolio. Inside Information. From time to time, Cormorant or its affiliates may possess material non-public information concerning the issuer of securities or other instruments in which a Fund has invested, or as to which it is evaluating an investment. The possession of such information may affect Cormorant’s ability to cause such Fund to buy or sell such securities or other instruments. Accordingly, such Fund may be required to refrain from buying or selling such securities or other instruments at times when Cormorant might otherwise wish to cause the Fund to buy or sell such securities or other instruments. Cormorant has policies and procedures in place that seek to ensure that its investment practices do not violate federal and state securities law prohibitions on trading on inside information. Leverage. Where appropriate, Cormorant may use leverage and may increase the use of leverage by various means, which may include increasing the number and extent of the “long” positions by borrowing (e.g., by purchasing securities on margin) and entering into short sales. Such leverage increases both the possibilities for profit and the risk of loss. In a downward trending market, using leverage for long positions could have a material adverse effect on the Funds’ profitability and operations, and the reverse is true in a rising market with respect to short positions. However, Cormorant does not anticipate that the Funds will incur indebtedness in connection with their operations, other than interest on margin debts or deposits with respect to securities positions. Additionally, the Funds may use credit facilities to borrow against investor capital commitments for purposes of bridging or advancing funds to make portfolio investments pending capital contributions by Investors, resulting in the Funds being leveraged for periods in which borrowing is outstanding under these credit facilities. Risks of Investments in Options. Investing in options can provide greater potential for profit or loss than an equivalent investment in the underlying asset. An option’s value may decline because of a change in the underlying asset’s value relative to the strike price, the passage of time, changes in the market’s perception as to the future price behavior of the underlying asset, or any combination thereof. In the case of an option purchase, the risk of loss of an investor’s entire investment (i.e., the premium paid plus transaction charges)

reflects the nature of an option as a wasting asset that may become worthless when the option expires. Where an option is written or granted (i.e., sold) uncovered, the seller may be liable to pay substantial additional margin. The risk of loss for uncovered options is unlimited, as the seller will be obligated to deliver, or take delivery of, an asset at a predetermined price, which may, upon exercise of the option, be significantly different from the market value. Over-the-counter (“OTC”) options that Cormorant may use in its investment strategies generally are not assignable except by agreement between the parties concerned, and no party or purchaser has any obligation to permit such assignments. The OTC market for options is relatively illiquid, particularly for relatively small transactions. Short Sales. From time to time, Cormorant may engage in short sales as part of hedging transactions or when it believes securities are overvalued. Short sales are sales of securities that the Funds borrow but do not actually own. Short sales are usually made with the anticipation that the prices of the securities will decrease, thus creating the potential to profit by purchasing the securities at a later date at the lower prices. The Funds could incur a potentially unlimited loss on a short sale if the price of the security increases prior to the time it purchases the security to replace the borrowed security. A short sale presents greater risk than purchasing a security outright since there is no ceiling on the possible cost of replacing the borrowed security, whereas the risk of loss on a “long” position is limited to the purchase price of the security. Closing out a short position may cause the security to rise further in value thereby creating a greater loss. In recent years, short sale transactions have faced increased regulatory scrutiny in response to market events, including the imposition of restrictions on short selling certain securities and reporting requirements. Cormorant’s ability to execute a short selling strategy may be materially adversely impacted by temporary and/or new permanent rules, interpretations, prohibitions, and restrictions adopted in response to these adverse market events. Temporary restrictions and/or prohibitions on short selling activity may be imposed by regulatory authorities with little or no advance notice and may impact prior trading activities. Additionally, at any time, the SEC, its foreign counterparts, other governmental authorities, and/or selfregulatory organizations may promulgate permanent rules or interpretations consistent with such temporary restrictions or that impose additional or different permanent or temporary limitations or prohibitions. The SEC might impose different limitations and/or prohibitions on short selling from those imposed by various non-U.S. regulatory authorities. These different regulations, rules, or interpretations might have different effective periods. Regulatory authorities may impose restrictions that adversely affect the Funds’ ability to borrow certain securities in connection with short sale transactions. In addition, traditional lenders of securities might be less likely to lend securities under certain market conditions. Accordingly, Cormorant may not be able to effectively pursue a short selling strategy due to a limited supply of securities available for borrowing. Further, additional cost can be incurred in connection with short sale transactions, including situations where Cormorant is required to enter into a borrowing arrangement in advance of any short sales. Moreover, the ability to continue to borrow a security is not guaranteed and the Funds are subject to strict delivery requirements. The inability to deliver securities within the required time frame may lead to mandatory close out by the executing broker-dealer. A mandatory close out may subject the Funds to unintended costs and losses. Certain action or inaction by third-parties, such as executing broker-dealers or clearing broker-dealers, may materially impact Cormorant’s ability to effect short sale transactions. Such action or inaction may include a failure to deliver securities in a timely manner in connection with a short sale effected by an unrelated third-party. Purchasing Securities of Initial Public Offering. Occasionally, the Funds may purchase securities that are part of initial public offerings. The prices of these securities may be very volatile. The issuers of these securities may be undercapitalized, have a limited operating history, and lack revenues or operating income

without any prospects of achieving them in the near future. Some of these issuers may only make available a limited number of shares for trading. Therefore, it may be difficult to trade these securities without unfavorably impacting their prices. In addition, investors may lack extensive knowledge of the issuers of these securities. The Funds may invest in securities that are “new issues,” as defined by FINRA Rule 5130. FINRA Rule 5130 and Rule 5131 restricts certain persons from participating in “new issues.” Portfolio Liquidity and Transfer Restrictions (PIPEs and Similar Investments). The Funds may invest in so-called “PIPE” transactions, in which a private purchase of common stock or a security convertible into common stock is anticipated to be followed shortly by a registered public offering of such common stock, or of common stock of the same class. As securities sold in a PIPE transaction will generally be restricted only for the period from the private sale until the issuer’s registration statement with the SEC covering resale of such securities becomes effective, Cormorant may pay more for such securities than for other private placement securities. If the issuer is unable to obtain an effective resale registration statement for a PIPE, the PIPE will remain restricted under U.S. securities laws (subject to the availability of some other exemption) and Cormorant may be unable to recover from the issuer an amount sufficient to compensate for the loss of liquidity of such security. Investments in Special Purpose Acquisition Companies. A special purpose acquisition company (a “SPAC”) is a publicly traded company formed for the purpose of raising capital through an initial public offering to fund the acquisition through a merger, capital stock exchange, asset acquisition, or other similar business combination of one or more undervalued operating businesses. Following the acquisition of a target company, a SPAC typically would exercise control over the management of such target company in an effort to increase the value of such target company. Capital raised through the initial public offering of securities of a SPAC is typically placed into a trust until the target company is acquired or a predetermined time period elapses. SPAC investors would receive a return on their investment in the event that a target company is acquired and such target company’s value increased. If a SPAC cannot locate and acquire target companies by the deadline, the SPAC would be forced to liquidate its assets, which may result in losses due to the expenses and liabilities of the SPAC. SPAC investors are subject to the risk that, among other things, (i) such SPAC may not be able to locate or acquire a target company by the deadline, (ii) assets in the trust may be subject to third-party claims against such SPAC, which may reduce the per share liquidation price received by the SPAC investors, (iii) such SPAC may be exempt from the rules promulgated by the SEC to protect investors in “blank check” companies, such as Rule 419 promulgated under the Securities Act, so that investors in such SPAC may not be afforded the benefits or protections of those rules, (iv) such SPAC may only be able to complete one business combination, which may cause it to be solely dependent on a single business, (v) the value of any target company may decrease following its acquisition by such SPAC, (vi) the value of the funds invested and held in the trust decline, (vii) the inability to withdraw due to the failure to hold the securities in the SPAC on the record date or the failure to vote against the acquisition, and (viii) if the SPAC is unable to consummate a business combination, public stockholders will be forced to wait until the deadline before liquidating distributions are made. In addition, most SPACs are illiquid and have a concentrated shareholder base that tends to be comprised of institutional investors such as hedge funds (at least at inception). The Hedge Fund and PE Funds may invest in a SPAC that, at the time of investment, has not selected or approached any prospective target businesses with respect to a business combination. In such circumstances, there may be limited basis for the Funds to evaluate the possible merits or risks of such SPAC’s investment in any particular target business. To the extent that a SPAC completes a business combination, it may be affected by the numerous risks inherent in the business operations of the acquired company or companies. For these and additional reasons, SPAC investments are speculative and involve a high degree of risk. Market Disruptions; Governmental Intervention; Dodd-Frank Wall Street Reform; and Consumer

Protection Act. In recent years, the global financial markets have gone through pervasive and fundamental disruptions that have led to extensive governmental intervention. Such intervention was in certain cases implemented on an “emergency” basis, which suddenly and substantially eliminated market participants’ ability to continue to implement certain strategies or manage the risk of their outstanding positions. Furthermore, certain of these interventions have been unclear in scope and application, resulting in confusion and uncertainty, which in itself has been materially detrimental to the efficient functioning of the markets as well as previously successful investment strategies. The Dodd-Frank Wall Street Reform and Consumer Protection Act, as amended (the “Dodd-Frank Act”), which aims to reform various aspects of the U.S. financial markets, covers a broad range of market participants including investment advisers such as Cormorant. The Dodd-Frank Act may directly affect Cormorant by mandating additional new reporting requirements, including, but not limited to, position information, use of leverage, and counterparty and credit risk exposure. Until the SEC implements the new reporting requirements, it is unknown how burdensome such new reporting requirements will be. Pursuant to the Dodd-Frank Act, the Funds and Cormorant may be designated as “Systemically Important Financial Institutions” or “SIFIs”. Any entity designated will be subject to regulation by the Federal Reserve Board. In the area of derivatives, the Dodd-Frank Act provides for the registration and comprehensive regulation of “major swap participants.” Although Cormorant believes that is unlikely to be designated as a “major swap participant”, consequences of being so classified could be substantial and adverse. In addition, the cost of derivative transactions may substantially increase as a result of the DoddFrank Act as additional margin, capital, and collateral obligations are implemented. The Funds may incur major losses in the event of disrupted markets and other extraordinary events in which historical pricing relationships become materially distorted. The risk of loss from pricing distortions is compounded by the fact that in disrupted markets many positions become illiquid, making it difficult or impossible to close out positions against which the markets are moving. The financing available from banks, dealers, and other counterparties will typically be reduced in disrupted markets. Such a reduction may result in substantial losses. Market disruptions may from time to time cause dramatic losses and can result in otherwise historically low-risk strategies performing with unprecedented volatility and risk. Legal and Regulatory Environment for Private Investment Funds and Private Fund Advisers. The financial services industry generally, and the activities of hedge funds and private equity funds and their managers, in particular, have faced intense and increasing regulatory scrutiny. Such scrutiny may increase the Funds’ exposure to potential liabilities and to legal, compliance, and other related costs. Increased regulatory oversight may impose additional administrative burdens on Cormorant, including, without limitation, responding to inquiries and implementing new policies and procedures. Such burdens may direct Cormorant’s time, attention, and resources from portfolio management activities. It is impossible to predict what, if any, changes in law or regulation applicable to the Funds may be instituted in the future. New laws and regulations or actions taken by regulators that restrict the ability of the Fund to pursue its investment programs or employ counterparties could have a material adverse effect on Cormorant, the General Partners, any Fund, and/or any Investor. Broker Risk. The Funds’ assets may be held in one or more accounts maintained by its prime brokers or at other brokers or custodian banks, which may be located in various jurisdictions, including emerging markets. Prime brokers, other brokers (including those acting as sub-custodians), and custodian banks are subject to various laws and regulations in the relevant jurisdictions that are designed to protect their customers in the event of their insolvency. Accordingly, the practical effect of the laws protecting customers in the event of insolvency and their application to the Funds’ assets may be subject to substantial variations, limitations, and

uncertainties. In certain jurisdictions, for example, brokers could have title to the Funds’ assets or not segregate customer assets. Because of the large number of entities and jurisdictions involved and the range of possible factual scenarios involving the insolvency of a prime broker, another broker, or a clearing corporation, it is impossible to further generalize about the effect of the insolvency of any of them. Investors should assume that the insolvency of any of the prime brokers, local brokers, custodian banks, or clearing corporations may result in the loss of all or a substantial portion of the Funds’ assets or in a significant delay in having access to those assets. General Economic and Market Conditions. Cormorant’s success will be affected by general economic and market conditions, such as interest rates, credit availability, credit defaults, inflation rates, supply chain interruptions, economic uncertainty, changes in laws (including laws relating to taxation of the Fund’s investments), trade barriers, tariffs, currency exchange controls, and national and international political circumstances. Further, Cormorant’s activities can be affected by unforeseen events and circumstances beyond Cormorant’s control, including, without limitation, acts of God, war, riots, fire, flood, hurricane, earthquake, explosion, infectious disease outbreaks, pandemic or any other serious public health concern, act or threat of terrorism, labor strikes, theft, cyberattacks, malicious damage, electricity line rupture, energy blackouts, technology failure, social instability, etcetera. These factors may affect, among other things, the level and volatility of securities’ prices, the liquidity of the Funds’ investments, and the availability of certain securities and investments. Volatility or illiquidity could impair the overall profitability or result in losses. Momentum Investing; Online Investor Forums. Momentum investing by groups of individual retail investors and/or investment professionals could impact the value of one or more of the Fund’s holdings. In 2020 and early 2021, retail investors’ participation in U.S. equity order flows significantly increased as a result of numerous factors, including lockdowns during the COVID-19 pandemic, receipt of policy stimulus checks, low interest rates, and a proliferation of trading apps that allow smartphone users to buy or sell stocks for little or no fees. The impact of retail participation in the stock market is compounded by several factors. First, many retail investors buy and sell options on stocks and/or use margin made available by retail trading platforms, which has the effect of leverage and increases the volatility of the stock prices when trading occurs in large aggregate volumes. Second, online discussions about stocks on social media platforms such as Reddit, X (f/k/a Twitter), and Meta (f/k/a Facebook) have served as a venue for retail traders and analysts to collaborate and form collective views about specific issuers and trading, resulting in significant share price volatility that is not based on fundamental news or traditional valuation metrics. Moreover, these forums appear to be gaining influence among retail traders, leading to a greater likelihood that additional securities in the future will be the subject of collective momentum trading based on the populist consensus in the forums. A “short squeeze” occurs when a stock price jumps sharply higher, forcing investors that had bet that its price would fall by holding a short position, to buy it long in order to forestall incurring even greater losses. A market requirement that short sellers must post additional capital to cover the declining value of their short positions or to close out their short positions by buying such securities long adds to the upward momentum of the stock’s price. In turn, this may lead to investors (including retail momentum traders collaborating on social media platforms) to continue to buy the stock long, further increasing the price of the stock while open short positions further decline in value. There is no way to predict what issuers, if any, will become the subject of such trading. The share price swings resulting from retail momentum trading have caused, and could continue to cause, volatility to longer-term and fundamental investors. One or more of the Funds could suffer substantial losses if it is shorting a stock that is the subject of retail momentum trading, as in the case of a short squeeze. Additionally, a Fund could suffer losses on long positions it holds as a result of momentum driven sales.

More generally, the significant volatility resulting from these retail trading platforms could cause market uncertainty and disruption that impairs a Fund’s ability to execute its investment strategy and limits the effectiveness of such Fund’s trading strategies or results in losses to such Fund. Inflation/Deflation Risk. Inflation risk is the risk that the value of assets or income from the Funds’ investments will be worth less in the future as inflation decreases the value of payments at future dates. As inflation increases, the real value of a Fund’s portfolio could decline. Conversely, deflation risk is the risk that prices throughout the economy decline over time. Deflation may adversely affect the creditworthiness of issuers and may make issuer default more likely or materially impair the ability of distressed issuers to restructure, which may result in a decline in the net asset value of a Fund’s portfolio. Banking Exposure. Although inflation risk is particularly acute for bonds and other fixed income investments, it can also impact investments in equity securities and other instruments where the underlying issuer is sensitive to inflation risk. Banks and financial institutions that hold fixed income instruments can be negatively impacted by inflationary periods, which can reduce the value of such holdings and result in a loss of confidence in the institution. In such an event, loss of depositor confidence can lead to panic and ultimately could result in the affected bank becoming insolvent or facing bankruptcy. In the event of a bank insolvency or bankruptcy, depositors could lose up to the amount of their uninsured deposits with the bank. Conditions causing such losses can develop rapidly and without warning, making it impracticable or impossible for a company with a banking relationship with such institution to withdraw funds from or dispose of investments in such institutions before realizing losses. This risk is particularly applicable to investments and deposits held in regional banks and banks that are not systematically important to the U.S. economy. Many early stage companies, including early stage healthcare and biotech companies, have banking relationships with regional banks, which are susceptible to these risks. Risks Associated with Artificial Intelligence. Recent advancements in artificial intelligence (AI) present both opportunities and significant risks. Cormorant, its service providers, and Portfolio Companies may use artificial AI tools in certain circumstances. The use of AI presents risks, including potential exposure of confidential information, misuse of intellectual property, and reliance on inaccurate or misleading outputs. These risks may adversely affect Cormorant, its Advisory Clients, and Portfolio Companies. AI is subject to evolving regulatory scrutiny in the U.S. and abroad. Future legal or policy developments may impact the use of AI. The broader effects of AI on markets and industries remain uncertain. Risks Associated with the Hedge Fund Equity Securities of Growth Companies. A portion of the Hedge Fund’s assets may be invested in equity securities of companies that Cormorant believes have potential for capital appreciation significantly greater than that of the market averages, so-called “growth” companies. The market capitalization of the growth companies in which the Hedge Fund will invest may range from small to large capitalizations. Growth stocks are generally more sensitive to market movements than other types of stocks, primarily because their stock prices are based heavily on future expectations. Securities of growth companies may be traded in the OTC markets. While OTC markets have grown rapidly in recent years, many OTC securities trade less frequently and in smaller volume than exchange-listed securities. The values of these securities may fluctuate more sharply than exchange-listed securities. The Hedge Fund may experience some difficulty in acquiring or disposing of positions in these OTC securities at prevailing market prices. Service as a Company Officer and/or on Board of Directors. Individual representatives of Cormorant and its affiliates may serve as an officer, committee member, or a member of the board of directors of a company

that is the issuer of securities owned by the Hedge Fund. In their capacity as either an officer, committee member, or board member, such individuals may become subject to fiduciary, regulatory reporting, or other duties, which may adversely affect the Hedge Fund. For example, the Hedge Fund may be unable to sell or buy securities or enter into transactions that may benefit the Hedge Fund if a Cormorant representative possesses inside information concerning such portfolio investment. Undervalued and Overvalued Equity Securities. The Hedge Fund’s investment strategy focuses on investing in companies that Cormorant believes are undervalued and overvalued. Opportunities in undervalued equity securities arise from market inefficiencies or due to a lack of wide recognition of the potential impact (positive or negative) that specific events or trends may have on the security’s value. Opportunities in overvalued equity securities arise when a stock’s current price is not justified by its earnings outlook or price/earnings (P/E) ratio and, therefore, is expected to drop in price. Overvaluation may result from an emotional buying spurt, which inflates the stock’s market price, or from a deterioration in a company’s financial strength. The identification of investment opportunities in undervalued and overvalued securities is a difficult task. There is no assurance that such opportunities will be successfully recognized or acquired. While investing long in undervalued securities and investing short in overvalued securities present opportunities for above-average capital appreciation, these investments are risky and can result in substantial losses. Hedging. The Hedge Fund may utilize certain financial instruments and investment techniques for risk management or hedging purposes. There is no assurance that such risk management and hedging strategies will be successful. Success will depend on, among other factors, Cormorant’s ability to predict the future correlation, if any, between the performance of the instruments utilized for hedging purposes and the performance of the investments being hedged. Since the characteristics of many securities change as markets change or time passes, the success of these hedging strategies may also be subject to Cormorant’s ability to correctly and efficiently readjust and execute hedges. There is also a risk that such correlation will change over time rendering the hedge ineffective. It may be more difficult to hedge a position in a smaller cap issuer than a larger-cap issuer. The Hedge Fund’s portfolio is not expected to be completely hedged at all times. Moreover, at various times, Cormorant may elect to be more fully hedged and at other times hedged only to a limited extent, if at all. Accordingly, the Hedge Fund’s assets may not be adequately protected from market volatility and other conditions. Derivative Investments. Derivative instruments or “derivatives” include futures, options, structured securities, and other instruments and contracts that are derived from, or the value of which is related to, one or more underlying securities, financial benchmarks, currencies, or indices. Derivatives allow an investor to hedge or speculate upon the price movements of a particular security, financial benchmark currency, or index at a fraction of the cost of investing in the underlying asset. A derivative’s value depends largely upon price movements in the underlying asset. Therefore, many of the risks applicable to trading the underlying asset also apply to derivatives of such asset. However, there are numerous other risks associated with derivatives trading. For example, because many derivatives are leveraged, a relatively small adverse market movement may expose the Hedge Fund to the possibility of a loss exceeding the original amount invested. Derivatives may also expose investors to liquidity risk, as there may not be a liquid market within which to close or dispose of outstanding derivatives contracts. Swaps, certain options, and other custom instruments are subject to the risk of non-performance by the swap counterparty, including risks relating to the creditworthiness of the swap counterparty. Futures positions may be illiquid because certain commodity exchanges limit fluctuations in certain futures contract prices during a single day by regulations referred to as “daily price fluctuation limits” or “daily limits.” Under such daily limits, during a single trading day no trades may be executed at prices beyond the

daily limits. Once the price of a contract for a particular future has increased or decreased by an amount equal to the daily limit, positions in the future can neither be taken nor liquidated unless traders are willing to effect trades at or within the limit. This could prevent Cormorant from promptly liquidating unfavorable positions and subject the Hedge Fund to substantial losses. Forward Trading. Forward contracts and options thereon, unlike futures contracts, are not traded on exchanges and are not standardized; rather, banks and dealers act as principals in these markets and individually negotiate each transaction. Forward and “cash” trading is substantially unregulated. There is no limitation on daily price movements and speculative position limits are not applicable. For example, there are no requirements with respect to record keeping, financial responsibility, or segregation of customer funds or positions. In contrast to exchange-traded futures contracts, interbank traded instruments rely on the dealer or contracting counterparty to fulfill its contract. As a result, trading in interbank foreign exchange contracts may be subject to more risks than futures or options trading on regulated exchanges, including, but not limited to, the risk of default due to the failure of a counterparty with which the Hedge Fund has forward contracts. Although Cormorant seeks to trade with responsible counterparties, failure by a counterparty to fulfill its contractual obligation could expose the Hedge Fund to unanticipated losses. The principals who deal in the forward markets are not required to continue to make markets in the currencies or commodities they trade and these markets can experience periods of illiquidity, sometimes of significant duration. There have been periods where certain participants in these markets have refused to quote prices with an unusually wide spread between the price at which they were prepared to buy and that at which they were prepared to sell. Disruptions can occur in any currency market traded by the Hedge Fund due to unusually high trading volume, political intervention, or other factors. The imposition of controls by governmental authorities might also limit such forward trading to less than that which Cormorant would otherwise recommend, to the possible detriment of the Hedge Fund. Market illiquidity or disruption could result in significant losses to the Hedge Fund. Foreign Securities. The Hedge Fund may invest in securities of non-U.S. issuers. Investments in foreign securities and instruments involve substantial risks not typically associated with investments in U.S. securities. Foreign securities investments may be affected by changes in currency rates or exchange control regulations, changes in governmental administration or economic or monetary policy (in the United States and abroad), or changed circumstances in dealings between nations. Changes in foreign currency exchange rates relative to the U.S. dollar will affect the U.S. dollar value of the Hedge Fund’s assets denominated in that currency and thereby impact total return on such assets. The Hedge Fund may utilize options and forward contracts to hedge against currency fluctuations, but there can be no assurance that such hedging transactions will be effective. Investments in foreign securities could also carry risks relating to political and economic developments abroad, including the possibility of expropriations or confiscatory taxation, limitations on the use or transfer of Hedge Fund assets, and any effects of foreign social, economic, or political instability. Foreign companies are not subject to the regulatory, reporting, accounting, auditing, and financial reporting standards and requirements of U.S. companies. Accordingly, there may be less publicly available information about such companies. Finally, in the event of a default of any foreign debt obligations, it may be more difficult for the Hedge Fund to obtain or enforce a judgment against the issuers of such securities. Securities of foreign issuers may be less liquid than comparable securities of U.S. issuers and, as such, their price changes may be more volatile. Furthermore, foreign exchanges and broker-dealers are generally subject to less government and exchange scrutiny and regulation than their American counterparts. Brokerage commissions, dealer concessions, and other transaction costs may be higher in foreign markets than in the U.S. Additionally, differences in clearance and settlement procedures in foreign markets may

cause delays in settlements of the Hedge Fund’s trades affected in such markets. Furthermore, changes or modifications in existing judicial decisions or in the current positions of the Internal Revenue Service, either taken administratively or as contained in published revenue rulings and revenue procedures (which changes or modifications may apply with retroactive effect), and the passage of new legislation could lead to unfavorable treatment of certain non-U.S. investments, which could adversely impact the Hedge Fund’s portfolio. Exchange Traded Funds. Cormorant may invest in and sell short shares of exchange traded funds (“ETFs”) and other similar instruments. ETFs and other similar instruments involve risks generally associated with investments in a broadly based portfolio of common stocks, including the risk that the general level of stock prices, or that the prices of stocks within a particular sector, may increase or decrease, thereby affecting the value of the shares of the ETF or other similar instruments. American Depository Securities and Receipts. In certain instances, rather than directly holding securities of non-U.S. companies, the Hedge Fund may hold these securities through an American Depository Receipt (an “ADR”). An ADR is issued by a U.S. bank or trust company to evidence its ownership of securities of a non-U.S. company. The currency of an ADR may be U.S. dollars rather than the currency of the nonU.S. company to which it relates. An ADR’s value will not equal the value of the underlying non-U.S. securities to which the ADR relates due to numerous factors. These factors include the fees and expenses associated with holding an ADR, the currency exchange relating to the conversion of foreign dividends and other foreign cash distributions into U.S. dollars, and tax considerations such as withholding tax and different tax rates between the jurisdictions. Additionally, the rights of the Hedge Fund, as an ADR holder, may differ than the rights of holders of the underlying securities to which the ADR relates. The ADR market may be less liquid than that of the underlying securities. The foreign exchange risk will also affect the ADR’s value and, therefore, the performance of the investor holding the ADR. Loans of Portfolio Securities. The Hedge Fund may lend its portfolio securities on terms customary in the securities industry, enter into reverse repurchase agreements, or enter into other transactions constituting a loan of the Hedge Fund’s assets in an attempt to increase its income through the receipt of interest on the loan. In the event of the bankruptcy of the other party to a securities loan, the Hedge Fund could experience delays in recovering the securities it lent. To the extent that the value of the securities the Hedge Fund lent has increased, the Hedge Fund could experience a loss if such securities are not recovered. Counterparty Risk. Some markets in which the Hedge Fund may effect transactions are “over-the-counter” or “interdealer” markets. The participants in such markets are typically not subject to the credit evaluation and regulatory oversight to which members of “exchange-based” markets are subject. This exposes the Hedge Fund to the risk that a counterparty will not settle a transaction in accordance with its terms and conditions because of a dispute over the terms of the contract (whether or not bona fide) or because of a credit or liquidity problem, thus causing the Hedge Fund to suffer a loss. Such “counterparty risk” is accentuated for contracts with longer maturities where events may intervene to prevent settlement, or where the Hedge Fund has concentrated its transactions with a single or small group of counterparties. Counterparties in foreign markets face increased risks, including the risk of being taken over by the government or becoming bankrupt in countries with limited (if any) creditor rights. The Hedge Fund is not restricted from concentrating any or all of its transactions with one counterparty. The Hedge Fund’s ability to transact business with any one or number of counterparties and the absence of a regulated market to facilitate settlement may increase the potential for losses by the Hedge Fund. Counterparty risks also include the failure of executing brokers to honor, execute, or settle trades.

Pursuant to the Dodd-Frank Act, some derivatives transactions will be subject to mandatory clearing and margin requirements set forth by the clearinghouse. The additional margin, capital, and collateral obligations may increase the cost of derivatives transactions and thereby potentially decrease the profitability of certain positions. Transaction Execution and Costs. As Cormorant expects to actively manage the Hedge Fund’s portfolio, purchases and sales of investments may be frequent and may result in higher transaction costs. In many cases, relatively narrow spreads may exist between the prices at which the Hedge Fund will purchase and sell particular positions. The successful application of the Hedge Fund’s investment strategy will therefore depend, in part, upon the quality of execution of transactions, such as the ability of broker-dealers to timely and efficiently execute orders. Although Cormorant will seek to utilize brokerage firms that will afford superior execution capability to the Hedge Fund, there is no assurance that all of the transactions will be optimally executed. Furthermore, due to the degree of trading, total commission charges and other transaction costs may be high. The level of commission charges, as a Hedge Fund expense, may therefore be a factor in determining the Hedge Fund’s future profitability. Risks Associated with the PE Funds Investments in Portfolio Companies. From time to time, the Funds may form and/or acquire a minority or majority position in one or more Portfolio Companies. There are numerous risks associated with such investments (including several risks identified in other risk factors herein). A PE Fund, through Cormorant, may actively or passively participate in the management and control of the Portfolio Companies and may designate a Cormorant representative to serve on the boards or management committees of its Portfolio Companies. Additionally, the PE Funds may invest in Portfolio Companies with no readily identifiable assets. There is no assurance such assets will be acquired or if acquired that such Portfolio Company will be successful. Service as a Portfolio Company Officer and/or on Board of Directors. Individual representatives of Cormorant and its affiliates may serve as an officer, committee member, or a member of the board of directors of a Portfolio Company that is the issuer of securities owned by a PE Fund. In their capacity as either an officer, committee member, or board member, such individuals may become subject to fiduciary, reporting, or other duties, which may adversely affect the applicable PE Fund. For example, a PE Fund may be unable to sell or buy securities or enter into transactions that may benefit the PE Fund if a Cormorant representative possesses inside information relating to such portfolio investment. Early Stage Investments. The PE Funds may invest a portion of its assets in newly formed or pre-revenue Portfolio Companies. These investments are typically made at an early point in a company’s life cycle. Such companies may have shorter operating histories on which to evaluate future performance. “Early stage” or “seed” investments can create value inherent in particular companies or situations that can be realized only with substantial effort or expense. Often the success of the investment will depend not only on the efforts of its management team, but also upon actions of other key individuals or extraneous factors including political or economic developments over which Cormorant has little or no control. Many early stage companies face significant competition from other firms, both established and start-up. Early stage investments are typically made in firms that are seeking to develop and bring to market new, unproven technology. This endeavor is subject to numerous risks, including, but not limited to, failure to develop or perfect the technology as planned; obsolescence; patent infringement and similar claims that prevent the technology from being used or licensed; lack of market acceptance of the technology; and loss of key personnel. These companies are typically dependent on the abilities of key individuals, including founding entrepreneurs, owners or employees with critical technological skills or ownership of important

patents or other intellectual property, and marketing and financial professionals. The growth and development of early stage companies may depend on the regular injection of additional capital and financing beyond which the Fund is prepared or able to invest. Moreover, such financing may not be available from other sources. Venture stage companies are typically thinly staffed and may lack the internal resources or procedures and controls to detect and prevent accounting errors, or more serious losses caused by the misconduct or negligence of officers, employees, or agents. The significant returns that have been achieved in a small portion of venture capital investments have in large part resulted from the completion of highly successful initial public offerings or acquisitions that have permitted the venture investors to sell their equity interests at multiples of the original cost. There can be no assurance that, at the time a given venture investment matures, the public securities markets will support an initial public offering to permit such returns or that the venture-backed company’s fundamentals will warrant such returns. Non-Controlling Investments. The PE Funds may make minority equity investments in Portfolio Companies where it may have limited influence. Such a Portfolio Company may have economic or business interests or goals that are inconsistent with those of the PE Funds. The PE Funds may not be in a position to limit or otherwise protect the value of their investment in the Portfolio Company. Cormorant will, as a condition of making such investments, seek appropriate shareholder rights to protect the investments. The PE Funds’ control over the investment policies of these companies may also be limited. Controlling or Substantial Investment Positions. From time to time, the Funds may form or purchase (possibly with other accounts or funds managed by the General Partner, Cormorant, or their respective affiliates) a large enough position in a Portfolio Company to participate, actively or passively, in its management and control. The Funds, through the General Partner, may also designate a Cormorant representative to serve on the boards or management committees of such Portfolio Companies. There are numerous risks associated with such investments. At times, the Cormorant representative will be required to make decisions that he/she considers to be in the best interests of such Portfolio Company that at times may not be in the best interest of the Funds, and vice versa. In addition, the Funds may be subject to claims by other investors in such Portfolio Companies, who may, among other things, object to the manner in which the Funds exercises its rights to participate in the management of the Portfolio Companies. Creditors of the issuer might seek to hold the Funds responsible for obligations of such Portfolio Companies. A controlling group of shareholders might be subject to claims against such Portfolio Companies that arise in other areas, including, but not limited to, tort, securities, and environmental law. Defending any such claims may be very costly and time-consuming and any liability in connection therewith could be substantial and may be borne by the Funds. Down Round and Cram Down Financings. A Portfolio Company in which the PE Funds invests may experience a down round financing where the Portfolio Company raises capital that is based on the Portfolio Company’s valuation that is lower than the Portfolio Company's valuation in its prior financing round in which the PE Funds may have invested. As a result of the lower valuation, the equity outstanding immediately prior to the down round will suffer dilution. A Portfolio Company may also engage in a “cram down” financing. A cram down financing is a term that is often used to describe a down round financing in which existing investors lead a new financing that includes terms that may be severely dilutive to non-participating investors and that may include other features, such as forced conversions and “pay-toplay” mechanisms, that may have the perceived effect of punishing non-participating stockholders. In a severe cram down, existing stockholders who do not participate in the round may end up with little or no meaningful ownership stake in the Portfolio Company. In addition to further consolidating ownership of the Portfolio Company, investors willing to participate in a cram down financing may often also receive

ancillary deal terms and preferred stock rights and preferences (such as super-priority liquidation preferences, “drag along” rights, and special voting rights) that are superior to the prior rounds. If the PE Funds do not participate in a cram down financing, its equity ownership could be significantly reduced. Investments in Illiquid Assets. An investment in the PE Funds requires a long-term commitment with no certainty of return. Many investments may be illiquid. There can be no assurance that the PE Funds will be able to realize such investments at attractive prices or otherwise be able to effect a successful realization or exit strategy. Consequently, dispositions of such investments may require a lengthy time period or may result in distributions in-kind. Additionally, the PE Funds may acquire securities that cannot be sold except pursuant to a registration statement filed under the Securities Act, or in accordance with Rule 144 promulgated under the Securities Act. There can be no assurance that private purchasers can be found for such investments. Portfolio Investments Longer Than Term. Although Cormorant expects that the investments in Portfolio Companies will be disposed of prior to the end of the term, the PE Funds may have to sell, distribute, or otherwise dispose of its investments in Portfolio Companies at a disadvantageous time. The PE Funds, therefore, may sell, distribute, or otherwise dispose of its investments in Portfolio Companies for a price which is less than the price that could have been obtained if the investments in Portfolio Companies were held for a longer duration. Potential Liabilities. The PE Funds may negotiate the right to appoint one or more of the members, managers, directors, officers, or employees of Cormorant as a member of the Portfolio Company’s board of directors. Such membership on the board of directors of a Portfolio Company can result in the PE Funds or the individual director being named as a defendant in litigation or other disputes or investigations. Similarly, disputes arising out of down round financings may result in the PE Funds, or their management, being named as defendants. Typically, Portfolio Companies will have insurance to protect directors and officers, but this insurance may be inadequate. The PE Funds will also indemnify their management among others, for liabilities incurred in connection with operations including liabilities arising from such disputes. The Investors may be required to return distributions previously made to them to satisfy indemnification obligations. Cormorant intends to manage the PE Funds in a way that will minimize exposure to these risks. The possibility of successful claims or lawsuits or adverse regulatory action, however, cannot be eliminated and such events could have significant adverse effects. Limitations on Ability to Exit Investments. Cormorant expects to exit from its investments in two principal ways: (i) private sales and (ii) initial public offerings; provided, however, that in the event of an initial public offering, the PE Funds expect to hold the shares of the applicable Portfolio Company until such time as Cormorant determines in its sole discretion to dispose of such shares. At any particular time, one or both of these avenues may be unavailable, or timing with respect to these exit mechanisms may be inopportune. Accordingly, the ability to exit from and liquidate portfolio holdings may be constrained at any particular time. Contingent Liability on Disposition of Investments. Most of the PE Funds’ investments involve private securities. In connection with the disposition of an investment in private securities, the PE Funds may be required to make representations about the business and financial affairs of the Portfolio Company typical of those made in connection with the sale of a business. The PE Funds also may be required to indemnify the purchasers of such investment to the extent that any such representations are inaccurate or with respect to certain potential liabilities. These arrangements may result in contingent liabilities that ultimately yield funding obligations that Investors must satisfy to the extent of their investment in the PE Funds.

Reliance on Portfolio Company Management. The day-to-day operations of each Portfolio Company will be the responsibility of such Portfolio Company’s management team. Although Cormorant is responsible for monitoring the performance of each of its investments and generally intends to invest in Portfolio Companies operated by strong management, there can be no assurance that the existing management team or any successor will operate any such Portfolio Company in accordance with the PE Funds’ expectations. Competitive Marketplace and Difficulty of Locating Suitable Investments. The marketplace for investing in early stage biotechnology, healthcare, and life science companies is competitive and involves a high degree of uncertainty. Substantial capital and numerous funds have been dedicated to making investments in the private sector. In the future, additional funds with similar investment objectives and/or sourcing methodologies may be formed by other unrelated parties. There can be no assurance that there will be a sufficient number of suitable investment opportunities to enable the PE Funds to invest all of their commitments in opportunities that satisfy the investment strategy. The process of identifying, structuring, implementing, and realizing attractive investment opportunities is highly competitive. Cormorant will compete for investment opportunities with many other investors, some of which will have greater resources than the PE Funds. The PE Funds’ commitments may not be fully utilized if a sufficient number of attractive investments are not identified and consummated during the investment period. Follow-On Investments. The PE Funds may be called upon to provide follow-on funding for its Portfolio Companies or have the opportunity to increase its investment in Portfolio Companies. Any decision not to make follow-on investments or the inability to make them may have a substantial negative impact on a Portfolio Company in need of such an investment or may diminish the proportionate ownership in such Portfolio Company and thus the PE Funds’ ability to influence such Portfolio Company’s future management. Bridge Loans. From time to time, the PE Funds may lend to Portfolio Companies on a short-term, unsecured basis or otherwise invest on an interim basis in Portfolio Companies in anticipation of a future issuance of equity or long-term debt securities or other refinancing or syndication. Such bridge loans may be convertible into a more permanent, long-term security; however, for reasons not always in the PE Funds’ control, such long-term securities issuance or other refinancing or syndication may not occur and such bridge loans and interim investment may remain outstanding. In such an event, the interest rate on such loans may not adequately reflect the risk associated with the unsecured position taken by the PE Fund. Business Risks. The PE Funds’ investment portfolios consist primarily of securities issued by privately held companies whose operating results in a specified period will be difficult to predict. Such investments involve a high degree of business and financial risk, as well as risks related to general market conditions, which can result in substantial losses. Cybersecurity Risk The computer systems, networks, or devices used by Cormorant and its service providers employ various protections to prevent damage or interruption from computer viruses, computer and network failures, telecommunication failures, infiltration by unauthorized persons, and security breaches. Despite such precautionary measures, systems, networks, or devices can be breached. Cybersecurity breaches can negatively impact Cormorant and its Advisory Clients. Cybersecurity breaches can include unauthorized access to systems, networks, or devices; infection from computer viruses or other malicious software; and attacks that shut down, disable, slow, or otherwise disrupt operations, business processes, or website access or functionality. Cybersecurity breaches may cause

disruptions and impact business operations, potentially resulting in financial losses; impediments to trading; inability to transact business; violations of applicable privacy and other laws; regulatory fines; penalties; reputational damage; reimbursement or other compensation costs; additional compliance costs; and the inadvertent release of confidential information. Cormorant may incur costs related to forensic analysis of the origin and scope of a cybersecurity breach, identity theft, unauthorized use of proprietary information, and adverse reputational consequences or litigation. Similar adverse consequences could result from cybersecurity breaches affecting issuers of securities in which the Advisory Clients invest; counterparties of Cormorant and its Advisory Clients; governmental and other regulatory authorities; exchange and other financial market operators; banks; brokers; dealers; insurance companies; other financial institutions; and other parties. These operational and technological risks could have material adverse consequences for such entities, which in turn may cause the Funds to lose value.

Related Person Arrangements Cormorant Global Healthcare GP, LLC, Cormorant Private Healthcare GP, LLC, Cormorant Private Healthcare GP II, LLC, Cormorant Private Healthcare GP III, LLC, Cormorant Private Healthcare GP IV, LLC, Cormorant Private Healthcare GP V, LLC, and Cormorant Private Healthcare GP VI, LLC serve as general partners, and Cormorant PR serves as a sub-advisor, to the Advisory Clients, and are controlled by Bihua Chen. Paras Malde, Neb Obradovic, and Kevin Phillip serve as directors of the Offshore Feeder. Arrangements with Other Investment Advisers Cormorant does not recommend or select other investment advisers for its Advisory Clients nor does it have any other business relationships with any other advisers that create a material conflict of interest.

The Code sets forth a standard of business conduct that takes into account Cormorant’s status as a fiduciary and requires Access Persons to place the interests of the Advisory Clients above their own interests and Cormorant’s interests. The Code requires Access Persons to comply with applicable federal securities laws. Further, Access Persons are required to promptly bring Code violations to the attention of Cormorant’s Chief Compliance Officer. All Access Persons are provided with a copy of the Code and must acknowledge receipt of the Code upon hire and at least annually thereafter. The Code also sets forth certain reporting and pre-clearance requirements with respect to personal trading by Access Persons. Access Persons must provide the Chief Compliance Officer with a list of their personal accounts and an initial holdings report within 10 days of becoming an Access Person. Generally, Access Persons are not permitted to trade for their personal accounts securities held by the Advisory Clients, must obtain pre-approval before trading in reportable securities for their personal accounts, and are required to hold their personal investments for a certain predetermined time period. Additionally, Access Persons must provide annual holdings reports and quarterly transaction reports in accordance with Advisers Act Rule 204A-1. The Code also seeks to ensure the protection of non-public information about the Advisory Clients’ activities. Investors or prospective Investors may obtain a copy of the Code by contacting the Chief Compliance Officer, Neb Obradovic, at neb@cormorant-asset.com. Possible Conflicts of Interest As explained in Item 10 above, Cormorant Global Healthcare GP, LLC, Cormorant Private Healthcare GP, LLC, Cormorant Private Healthcare GP II, LLC, Cormorant Private Healthcare GP III, LLC, Cormorant Private Healthcare GP IV, LLC, Cormorant Private Healthcare GP V, LLC, and Cormorant Private Healthcare GP VI, LLC serve as the general partners to the Funds. The General Partners and Cormorant’s employees also invest directly in the Funds. Investments in the Funds made by such parties generally are not subject to the management or performance-based fees described in Item 5 above. Cormorant believes that Access Persons’ investments in Advisory Clients aligns the Access Persons’ interests with those of the Advisory Clients and their Investors. Nonetheless, the fact that the General Partner’s and Cormorant’s employees have significant financial ownership interests in certain Advisory Clients creates a potential conflict in that it could cause Cormorant to make different investment decisions absent such financial ownership interests. Cormorant addresses this potential conflict by impressing upon Access Persons their fiduciary duty to act in the best interests of the Advisory Clients and Investors. Moreover, Cormorant requires Access Persons to submit securities holdings and transaction reports in accordance with Rule 204A-1 by mandating pre-clearance process for certain personal securities transactions and prohibiting Access Persons from transacting in securities in the universe of securities in which Cormorant invests. Cormorant and its affiliates have a material financial interest with respect to fees paid by the Advisory

Clients and Investors. Management fees are payable regardless of the overall success or income earned by the Advisory Clients and therefore may incentivize Cormorant to raise or otherwise increase assets under management to a higher level than would be the case if Cormorant were receiving a lower or no management fee. Performance-based fees may incentivize Cormorant to make investments that are riskier or more speculative than in the absence of such incentive allocations. Additionally, one or more Access Persons are expected to serve on the board of directors of one or more Portfolio Companies and/or of one or more PE Funds, including, but not limited to, companies in which a PE Fund invests. As a result, the PE Funds may be restricted from transacting in securities of such issuers. Cormorant addresses these potential conflicts through regular monitoring of the Advisory Clients for consistency with the investment objectives, strategies, and target capacity. Further, Cormorant carefully considers the risks involved in any investments and provides extensive disclosure to Investors regarding the potential risks that come with an investment in the Advisory Clients. The Code requires Access Persons to place the Advisory Clients’ interests over their own and those of Cormorant. All Access Persons must acknowledge their receipt and understanding of the Code.

Cormorant also considers a variety of other factors, including the financial strength, integrity, and stability of the broker-dealer; the execution capabilities required by the transaction(s); the ability and willingness of the broker-dealer to facilitate transactions promptly and at reasonable expense; the importance to the account of speed, efficiency, or confidentiality; the broker-dealer’s apparent familiarity with sources from or to whom particular securities might be purchased or sold; and any other matters Cormorant deems relevant to the selection of a broker-dealer for a particular transaction. Cormorant may also consider the quality, comprehensiveness, and frequency of available research and other products and services considered to be of value. The products and services furnished by broker-dealers may include, among other things, written information and analyses concerning specific securities, companies or sectors, market, financial and economic studies and forecasts, statistics and pricing or appraisal services, discussion with research personnel, special execution capabilities, order of call, and the availability of stocks to borrow for short trades. Cormorant is authorized to pay higher prices for the purchase of securities from or accept lower prices for the sale of securities to brokerage firms that provide it with such research and trading related products and services or to pay higher commissions to such firms if Cormorant determines such prices or commissions are reasonable in relation to the overall services provided. Accordingly, the Advisory Clients may be deemed to be paying for research and other products and services with “soft” or commission dollars. Research and Other Soft Dollars Benefits Cormorant currently does not use commissions or “soft dollars” generated by the Advisory Clients to pay for brokerage and research products or services. Should Cormorant decide to use soft dollars in the future, such use will fall within the safe harbor created by Section 28(e) of the U.S. Securities Exchange Act of 1934, as amended. When a product or service obtained with soft dollars provides both research and non-

research assistance to the Advisory Clients, Cormorant will make a reasonable allocation of the cost attributable to research assistance that may be paid for with soft dollars pursuant to the Section 28(e) safe harbor referenced above. If in the future, Cormorant uses soft dollars to obtain research or other products or services from brokerdealers, it will receive a benefit because it does not have to produce or pay for the research, products, or services. Cormorant also has the authority to cause the Advisory Clients to pay broker-dealers directly for research. Further, Cormorant has an incentive to select or recommend a broker-dealer based on its interest in receiving the research or other products or services, rather than on an Advisory Client’s interest in receiving most favorable execution. Such soft dollar benefits may be used to service all of Cormorant’s Advisory Clients and not just those that paid for the benefits. It is anticipated that any soft dollar benefits received by Cormorant will be applicable to all of Cormorant’s Advisory Clients. Brokerage for Client Referrals Cormorant does not consider whether it receives client referrals from a broker in selecting broker-dealers. Directed Brokerage Cormorant does not recommend, request, or require that a client direct Cormorant to execute transactions through a specified broker-dealer. Trade Aggregation and Allocation When the purchase and sale of securities is considered to be in the best interest of more than one Advisory Client, the securities to be purchased or sold may be aggregated in order to obtain superior execution and/or lower brokerage expenses. Advisory execution prices for identical securities purchased or sold on behalf of multiple accounts in any one day may be (but are not required to be) averaged. In such instances, allocation of prices, as well as expenses incurred in the transaction, will be made in a manner that Cormorant considers to be equally as favorable to the Advisory Clients as to any other party. Allocation of investment opportunities (as applicable) among the Advisory Clients will be made by Cormorant based upon such factors as Cormorant deems appropriate, including, without limitation, the investment objectives and available investment capital of the Advisory Clients. Neither Cormorant nor any of its principals, members, managers, affiliates, or employees are under any obligation to first offer any investment opportunities to a particular Advisory Client or to allocate investments, as between one Advisory Client or another, in any particular manner, other than as Cormorant in its sole discretion shall determine; provided, that Cormorant will seek to allocate investment opportunities that are appropriate for more than one Advisory Client on a “pari-passu” basis. No allocations may be made to an Advisory Client based on such Advisory Client’s performance or the amount or structure of fees. Allocations of limited opportunity investments such as IPOs will be allocated in the same manner as other securities.

Investors investing in one of Cormorant’s privately offered funds must execute a subscription agreement in which they make various representations, including representations regarding their suitability to invest in a high-risk investment pool. Further, Investors investing in Cormorant’s privately offered funds domiciled in the U.S. must execute a limited partnership agreement that contains a limited power of attorney. Cormorant has discretionary authority to manage the Account. The Account is subject to investment objectives, guidelines, restrictions, and fee arrangements, as well as other terms that are individually negotiated with the Account owner and set forth in an investment management agreement.

At times, Cormorant may abstain from voting proxies, if doing so is in the best interest of its Advisory Clients, or otherwise appropriate, such as when its Advisory Clients have exited their position in a particular issuer. Cormorant will not allow its Investors to direct Cormorant’s vote in a particular situation. Cormorant constantly monitors for occasions in which the voting of proxies could present a conflict of interest between Cormorant and its Advisory Clients. If Cormorant believes that a material conflict of interest exists with respect to any proxy vote, the Chief Compliance Officer will consult with the Portfolio Manager, and outside counsel, if necessary, to resolve the conflict. In such situations, Cormorant will generally seek to mitigate the conflict by either appointing an independent third party to vote such proxies or will disclose the conflict to the affected Advisory Client (or its Investors) and consult with such Advisory Client (or its Investors) on how to vote. The Advisory Clients and Investors may obtain (i) additional information regarding how Cormorant voted proxies and (ii) a copy of Cormorant’s proxy voting policies and procedures by contacting the Chief Compliance Officer, Neb Obradovic, at neb@cormorant-asset.com.