4528 on Tokyo Stock Exchange

Ono Pharmaceutical

Logo: Ono Pharmaceutical Co., Ltd., Public domain, via Wikimedia Commons3

Japanese pharmaceutical company

Ono Pharmaceutical Co., Ltd. (小野薬品工業株式会社, Ono Yakuhin Kōgyō Kabushiki-gaisha) is one of the largest pharmaceutical companies in Japan. It is headquartered in Chuo-ku, Osaka, Japan, with its major plants in Higashinari-ku, Osaka, and Fujinomiya, Shizuoka., and its central research institute at Minase, Shimamoto-cho, Mishima District, Osaka. Ono Pharmaceutical's roots go back to 1717 when Ichibei Ono (Japanese: 小野市兵衛) started his dealer business of pharmaceuticals in Osaka.2 Its shares trade on Tokyo Stock Exchange under the symbol 4528.1 Wikipedia text CC BY-SA 4.0

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Last updated Oct 21, 2026.

Overview

Jul 4, 1947Founded1

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  • Ticker4528 on Tokyo Stock Exchange1
  • Industrypharmaceutical industry1
  • HeadquartersChūō-ku1
  • Websitewww.ono.co.jp
  • Legal formkabushiki gaisha1

Ono Pharmaceutical Co., Ltd. (小野薬品工業株式会社, Ono Yakuhin Kōgyō Kabushiki-gaisha) is one of the largest pharmaceutical companies in Japan. It is headquartered in Chuo-ku, Osaka, Japan, with its major plants in Higashinari-ku, Osaka, and Fujinomiya, Shizuoka., and its central research institute at Minase, Shimamoto-cho, Mishima District, Osaka.2

Corporate structure

Ono Pharmaceutical sits at the top of its group. 2 entities, 2 countries on record. Switch between the flow chart and the network, and select any entity to see its details.

Built from subsidiaries, stakes and holdings from Wikidata (CC0); major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

Subsidiaries and ownership

Subsidiaries

From Wikidata.1

Timeline

  1. Jul 4, 1947Founded Founded1

Calendar

Drug trials and FDA: coming up

  1. Dec 31, 2026Phase 2 trial readout expected Phase 2 trial of ONO-2020 in Agitation Associated With Alzheimer's Disease Dementia: primary completion expected Dec 31, 2026 (ClinicalTrials.gov NCT06803823).4
  2. Jan 31, 2027Phase 3 trial readout expected Phase 3 trial of Cenobamate in Epilepsy, Generalized: primary completion expected Jan 31, 2027 (ClinicalTrials.gov NCT06579573).5
  3. Jan 31, 2027Phase 2 trial readout expected Phase 2 trial of Cenobamate in Epilepsies, Partial: primary completion expected Jan 31, 2027 (ClinicalTrials.gov NCT06590896).6
  4. Mar 31, 2027Phase 1/2 trial readout expected Phase 1/2 trial of E7389-LF and Nivolumab in Solid Neoplasms, run by Eisai Co., Ltd.: primary completion expected Mar 31, 2027 (ClinicalTrials.gov NCT04078295).7
  5. Sep 30, 2027Phase 3 trial readout expected Phase 3 trial of ONO-4059 in Pemphigus: primary completion expected Sep 30, 2027 (ClinicalTrials.gov NCT06696716).8

Drug trials and FDA: recently

  1. May 27, 2026Phase 3 trial completed Phase 3 trial of Nivolumab in Hepatocellular Carcinoma, run by Bristol-Myers Squibb: primary completion May 27, 2026, no results posted yet (ClinicalTrials.gov NCT03383458).9
  2. Feb 16, 2026Phase 3 trial completed Phase 3 trial of Nivolumab, Gemcitabine and others in Urinary Bladder Neoplasms, run by Bristol-Myers Squibb: primary completion Feb 16, 2026, no results posted yet (ClinicalTrials.gov NCT03661320).10
  3. Mar 1, 2025Phase 3 trial completed Phase 3 trial of Encorafenib, Cetuximab and others in Neoplasms, run by Pfizer: primary completion Mar 1, 2025, results posted Jun 11, 2026 (ClinicalTrials.gov NCT04607421).11

Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). Trials from ClinicalTrials.gov, as the sponsor registered them (expected dates are the sponsor's own and often move); approvals and advisory committee meetings from the FDA. The FDA does not publish its decision (PDUFA) dates. The full markets calendar

Sources

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