ABSI on Nasdaq

Absci Corp

In its 2026 annual report the company says: “We are a clinical-stage biopharmaceutical company using an AI-native approach to develop differentiated antibody therapeutics. Our integrated drug creation platform combines Origin-1, our generative design model, with rapid validation using our lab-in-the-loop. We focus on underexplored mechanisms where unmet medical need is high and competition is low.”4 It is headquartered in Vancouver, Washington.1 Its shares trade on Nasdaq under the symbol ABSI.1

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Last updated Oct 21, 2026.

Overview

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  • TickerABSI on Nasdaq1
  • IndustryServices-Commercial Physical & Biological Research1
  • HeadquartersVancouver, Washington1
  • Business address18105 Se Mill Plain Blvd, Vancouver, Wa 986832
  • Filer categoryNon-accelerated filer, Smaller reporting company, Emerging growth company2

We are a clinical-stage biopharmaceutical company using an AI-native approach to develop differentiated antibody therapeutics. Our integrated drug creation platform combines Origin-1, our generative design model, with rapid validation using our lab-in-the-loop. We focus on underexplored mechanisms where unmet medical need is high and competition is low.4 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-4297.0%Operating margin5
-4113.7%Net margin5
-38.2%Revenue growth, 20255
-60.8%Return on equity5
-$94.0MFree cash flow5

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Research and development70¢$81.4M
  • Selling, general and admin30¢$35.1M
  • Income tax0¢$69.0K

Out of $2.8M in revenue.5 The company lost money this year.

Financial statements

Revenue67895$2.8M in 2025−41% since 2020
0$2.0M$4.0M$6.0M2020: $4.8M$4.8M20202021: $4.8M$4.8M2021+0%2022: $5.7M$5.7M2022+20%2023: $5.7M$5.7M2023−1%2024: $4.5M$4.5M2024−21%2025: $2.8M$2.8M2025−38%
Operating income67895-$120.3M in 2025+805% since 2020
-$150.0M-$100.0M-$50.0M02020: -$13.3M-$13.3M20202021: -$75.2M-$75.2M2021+466%2022: -$106.8M-$106.8M2022+42%2023: -$115.5M-$115.5M2023+8%2024: -$108.9M-$108.9M2024−6%2025: -$120.3M-$120.3M2025+10%
Net income67895-$115.2M in 2025+703% since 2020
-$150.0M-$100.0M-$50.0M02020: -$14.4M-$14.4M20202021: -$101.0M-$101.0M2021+603%2022: -$104.9M-$104.9M2022+4%2023: -$110.6M-$110.6M2023+5%2024: -$103.1M-$103.1M2024−7%2025: -$115.2M-$115.2M2025+12%

Every line of the income statement as filed: the last 2 fiscal years, latest first.5

Period ending2025-12-312024-12-31
Partner program revenue$2.8M$4.5M
Research and development$81.4M$63.9M
Selling, general and administrative$35.1M$36.2M
Depreciation and amortization$11.7M$13.4M
Gain on settlement of contingent consideration-$5.1M$0
Total operating expenses$123.1M$113.4M
Operating loss-$120.3M-$108.9M
Interest expense-$209.0K-$565.0K
Other income, net$5.4M$6.4M
Total other income, net$5.2M$5.9M
Loss before income taxes-$115.1M-$103.0M
Income tax expense-$69.0K-$70.0K
Net loss-$115.2M-$103.1M
Net loss per share: basic (in usd per share)-$0.84-$0.94
Net loss per share: diluted (in usd per share)-$0.84-$0.94
Weighted-average common shares outstanding: basic (in shares)136.8M shares110.2M shares
Weighted-average common shares outstanding: diluted (in shares)136.8M shares110.2M shares
Foreign currency translation adjustments$448.0K-$26.0K
Unrealized gain on marketable securities$147.0K$59.0K
Comprehensive loss-$114.6M-$103.1M

Compare Absci Corp with another company

Corporate structure

Absci Corp sits at the top of its group. 4 entities, 2 countries on record. Switch between the flow chart and the network, and select any entity to see its details.

Major holders of Absci Corp

  • Redmile Group, LLC Filed SCHEDULE 13D/A on Absci Corp, latest Apr 14, 2026 (4 filings since Mar 5, 2024)
  • VANGUARD GROUP INC Filed SCHEDULE 13G/A on Absci Corp, latest Mar 26, 2026 (4 filings since Jul 29, 2025)
  • Sean McClain Filed SCHEDULE 13G/A on Absci Corp, latest Nov 13, 2025 (5 filings since Feb 11, 2022)
  • BlackRock Filed SCHEDULE 13G/A on Absci Corp, latest Jul 16, 2025 (3 filings since Oct 18, 2024)
  • ALGER ASSOCIATES INC Filed SCHEDULE 13G/A on Absci Corp, latest May 15, 2025 (3 filings since Nov 14, 2024)
  • Phoenix Venture Partners II LP Filed SCHEDULE 13G/A on Absci Corp, latest May 15, 2025 (5 filings since Feb 14, 2022)
  • ARK Investment Management LLC Filed SCHEDULE 13G/A on Absci Corp, latest May 14, 2025 (3 filings since Jan 10, 2025)
  • FMR LLC Filed SCHEDULE 13G/A on Absci Corp, latest May 12, 2025 (6 filings since Oct 12, 2021)
  • Casdin Capital, LLC Filed SC 13D/A on Absci Corp, latest May 8, 2023 (4 filings since Jul 21, 2022)
  • Mark Valasek Filed SC 13G on Absci Corp, latest Feb 14, 2022
  • Absci Corp Vancouver, Washington
    • Absci d.o.o. Beograd Subsidiary · Serbia
    • De Novo Design, LLC Subsidiary · Delaware, United States
    • Target Discovery Merger Sub II, LLC Subsidiary · Delaware, United States

Built from subsidiaries listed in Exhibit 21 of annual reports filed with the SEC; major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

What it owns

What Absci Corp reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.

Property and equipment

ItemLatestA year beforeChange
Operating-lease assets (leased space)$2.9M5 Dec 31, 2025$4.0M5 Dec 31, 2024−26.6%

Investments

ItemLatestA year beforeChange
Cash and cash equivalents$20.0M5 Dec 31, 2025$41.2M5 Dec 31, 2024−51.4%
Marketable securities, current$124.3M5 Dec 31, 2025$71.2M5 Dec 31, 2024+74.5%
Marketable securities, non-current$11.8M5 Dec 31, 2025

Intangibles and goodwill

ItemLatestA year beforeChange
Intangible assets, net (excluding goodwill)$41.5M5 Dec 31, 2025$44.9M5 Dec 31, 2024−7.5%
Finite-lived intangibles, gross$57.1M5 Dec 31, 2025$57.1M5 Dec 31, 20240%
Accumulated amortization$15.6M5 Dec 31, 2025$12.2M5 Dec 31, 2024+27.6%
Finite-lived intangibles, net$41.5M5 Dec 31, 2025$44.9M5 Dec 31, 2024−7.5%

Properties, in its own words

Our corporate headquarters and primary research and development facilities are located in Vancouver, Washington in a 77,974 square foot facility that includes general administrative office and laboratory space. Our AI Research Lab is located in New York, New York and our Innovation Center is located in Zug, Switzerland. Additionally, we have research and development presence in Belgrade, Serbia. Substantially all of our office space is leased with varying expiration dates. We believe our facilities are adequate and suitable for our current and near future needs.

Item 2 of the 10-K filed Mar 24, 2026.4

Leadership

Who has led Absci Corp, and when. Pick a name to see everywhere that person has worked.

Chief operating officer

  1. Andreas Pihl2021
2025
Board members and other officers (18)

Subsidiaries and ownership

Subsidiaries (Exhibit 21)

  • AbSci, LLC Delaware3
  • Absci GmbH Switzerland3
  • Absci Pty Ltd Australia3
  • Absci d.o.o. Beograd Serbia3
  • De Novo Design, LLC Delaware3
  • Target Discovery Merger Sub II, LLC Delaware3

The subsidiaries the company lists in Exhibit 21 of its annual report, as filed.

Former names

  • AbSci, LLCApr 21, 2016 to Dec 19, 20192

Timeline

  1. Aug 11, 20268-K Results of operations; Other events33
  2. Jun 24, 20268-K Other events34
  3. Jun 24, 20268-K Entered a material agreement; Other events35
  4. Jun 5, 20268-K Shareholder vote36
  5. May 7, 20268-K Results of operations; Other events37
  6. Mar 24, 20268-K Results of operations; Other events38
  7. Mar 6, 20268-K Entered a material agreement; Executive or director change; Regulation FD disclosure39
  8. Jan 14, 20268-K Other events40
  9. Nov 12, 20258-K Results of operations; Other events41
  10. Nov 4, 20258-K Entered a material agreement42
  11. Aug 12, 20258-K Results of operations; Other events43
  12. Aug 12, 20258-K Results of operations; Other events44

Calendar

Coming up

  1. Nov 12, 2026 · Before the openReports results for the quarter ending Sep/2026 A year earlier it reported ($0.20) a share, on Nov 12, 2025.45

When it reported results

  1. Aug 11, 2026Reported quarterly or annual results33
  2. May 7, 2026Reported quarterly or annual results37
  3. Mar 24, 2026Reported quarterly or annual results38
  4. Nov 12, 2025Reported quarterly or annual results41
  5. Aug 12, 2025Reported quarterly or annual results43
  6. Aug 12, 2025Reported quarterly or annual results44
  7. May 13, 2025Reported quarterly or annual results46
  8. Mar 18, 2025Reported quarterly or annual results47

Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar

Filings

294 filings to the SEC since October 2021: 6 annual reports, 15 quarterly reports, 54 major events, 137 insider forms, 38 large holders, 44 other. The latest 20:

  1. Oct 14, 20264 EDGAR
  2. Oct 14, 20264 EDGAR
  3. Oct 14, 20264 EDGAR
  4. Sep 1, 20264 EDGAR
  5. Aug 11, 202610-Q EDGAR
  6. Aug 11, 20268-K EDGAR
  7. Aug 7, 20264 EDGAR
  8. Aug 7, 20263 EDGAR
  9. Jul 6, 20264 EDGAR
  10. Jun 26, 20264 EDGAR
  11. Jun 24, 20268-K EDGAR
  12. Jun 24, 20268-K EDGAR
  13. Jun 24, 2026424B5 EDGAR
  14. Jun 15, 20264/A EDGAR
  15. Jun 11, 20264 EDGAR
  16. Jun 8, 20264 EDGAR
  17. Jun 8, 20264 EDGAR
  18. Jun 8, 20264 EDGAR
  19. Jun 8, 20264 EDGAR
  20. Jun 8, 20264 EDGAR

The 294 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

23 open-market trades by officers, directors and large owners since October 2021: 12 buys and 11 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Jun 30, 2026Szela Mary TDirectorBuy12,900$11.54$148.9KForm 4
May 13, 2026Pangalos Menelas NDirectorBuy37,453$5.36$200.7KForm 4
Mar 12, 2026Busch AndreasChief Innovation OfficerBuy100,000$2.29$229.0KForm 4
Feb 27, 2026Pangalos Menelas NDirectorBuy75,095$2.74$205.8KForm 4
Feb 2, 2026McClain SeanChief Executive OfficerSale26,761$2.99$80.0KForm 4
Feb 2, 2026Jonasson ZachariahCFO / CBOSale17,496$2.99$52.3KForm 4
Dec 5, 2025VAN HOUTEN FRANSDirectorBuy40,000$3.72$148.8KForm 4
Sep 22, 2025Pangalos Menelas NDirectorBuy95,785$2.66$254.8KForm 4
Sep 22, 2025Bedrick ToddSVP, CAOBuy10,000$2.70$27.0KForm 4
Jul 28, 2025Busch AndreasChief Innovation OfficerBuy50,000$3.04$152.0KForm 4
Jun 13, 2024Jonasson ZachariahCFO / CBOSale19,859$4.98$98.9KForm 4
May 22, 2024Phoenix Venture Partners II LP10% ownerSale3,100,000$4.40$13.6MForm 4
Mar 1, 2024Green JeremyDirectorBuy222,222$4.50$1.0MForm 4
Nov 28, 2023Phoenix General Partner II LLC10% ownerSale40,439$1.44$58.2KForm 4
Nov 27, 2023Phoenix General Partner II LLC10% ownerSale12,959$1.40$18.1KForm 4
Nov 24, 2023Phoenix General Partner II LLC10% ownerSale10,779$1.42$15.3KForm 4
Nov 22, 2023Phoenix General Partner II LLC10% ownerSale3,508$1.40$4.9KForm 4
Nov 21, 2023Phoenix General Partner II LLC10% ownerSale1,237$1.40$1.7KForm 4
Nov 20, 2023Phoenix General Partner II LLC10% ownerSale24,369$1.43$34.8KForm 4
Nov 17, 2023Phoenix General Partner II LLC10% ownerSale20,000$1.43$28.6KForm 4

All 23 trades can be filtered by person here when JavaScript is on.

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Executive pay

What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.

YearExecutiveAgeSalaryTotal pay
2025Sean McClainPresident, Founder and Chief Executive Officer36$689.9K$3.7M58
2025Zachariah Jonasson, Ph.D.Chief Financial Officer and Chief Business Officer53$553.5K$2.3M58
2025Andreas Busch, Ph.D.Chief Innovation Officer*$712.8K$1.6M58
2024Sean McClainPresident, Founder and Chief Executive Officer36$660.4K$9.8M58
2024Zachariah Jonasson, Ph.D.Chief Financial Officer and Chief Business Officer53$533.0K$2.8M58
2024Andreas Busch, Ph.D.Chief Innovation Officer*$654.1K$2.6M58

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Fmr LLC25,410,048$294.5M0.0%+2,859,051
ARK Investment Management LLC12,925,271$149.8M1.0%−800,898
BlackRock, Inc.12,175,302$141.1M0.0%+920,108
State Street Corp8,097,308$93.8M0.0%+772,450
Ameriprise Financial Inc6,991,763$81.0M0.0%+3,811,622
Redmile Group, LLC6,739,675$78.1M5.2%−1,513,641
Vanguard Capital Management LLC6,122,677$71.0M0.0%+236,037
Advanced Micro Devices Inc5,714,285$66.2M5.0%No change
Adage Capital Partners Gp, L.l.c.5,704,820$66.1M0.1%New
Two Sigma Investments, LP5,493,486$63.7M0.0%+2,594,720
D. E. Shaw & Co., Inc.5,239,754$60.7M0.0%+4,589,937
Geode Capital Management, LLC3,583,163$41.5M0.0%+240,095
Woodline Partners LP2,700,675$31.3M0.1%−599,494
Siren, L.L.C.2,474,764$28.7M0.6%+674,764
Bvf Inc/il2,361,674$27.4M0.7%New
Gem Investment Advisors, LLC2,170,863$25.2M15.4%No change
Baker Bros. Advisors LP2,134,803$24.7M0.1%No change
Goldman Sachs Group Inc1,732,324$20.1M0.0%+1,140,612
Nuveen, LLC1,723,979$20.0M0.0%+1,381,290
Voloridge Investment Management, LLC1,602,916$18.6M0.1%New
Morgan Stanley1,374,693$15.9M0.0%+888,068
Vanguard Portfolio Management LLC1,339,024$15.5M0.0%+537,961
Fred Alger Management, LLC1,176,797$13.6M0.0%+11,653
Charles Schwab Investment Management Inc1,165,995$13.5M0.0%+81,731
UBS Group AG1,138,844$13.2M0.0%−460,965

13F reports cover disclosed long positions in U.S. stocks only.

SEC filer profile

How Absci Corp is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.

  • Name on EDGARAbsci Corp1
  • CIK0001672688
  • Employer ID (EIN)85-33834874
  • Filer statusNon-accelerated filer an emerging growth company; a smaller reporting company; not a shell company4
  • Incorporated inDelaware4
  • Fiscal year endsDecember 311
  • Industry code (SIC)8731 Services-Commercial Physical & Biological Research1
  • SEC reviewing officeOffice of Industrial Applications and Services, Division of Corporation Finance1
  • Business address18105 Se Mill Plain Blvd, Vancouver, WA 986831
  • Phone(360) 949-10411
  • Shares outstanding171,614,010 as of Jul 31, 202611
  • Public float$303.8M as of Jun 30, 20254
  • AuditorErnst & Young LLP, San Jose, California PCAOB ID 42; no auditor attestation of internal control over financial reporting4
  • On EDGAR sinceApr 21, 20161
  • Filings358 in all: 4 (131), 8-K (56), 3 (23), 10-Q (16), SCHEDULE 13G/A (12), CORRESP (10), UPLOAD (9), 4/A (8)1
    All 39 form types

    SC 13G (8), SC 13G/A (7), 424B5 (6), S-8 (6), 10-K (5), D (5), DEF 14A (5), DEFA14A (5), SC 13D/A (5), ARS (4), EFFECT (4), S-1/A (4), S-3 (3), SCHEDULE 13D/A (3), SCHEDULE 13G (3), 424B3 (2), D/A (2), SC 13D (2), SEC STAFF LETTER (2), 10-K/A (1), 144 (1), 424B4 (1), 5 (1), 8-A12B (1), 8-K/A (1), CERT (1), DRS (1), DRS/A (1), DRSLTR (1), PRE 14A (1), S-1 (1)

  • Latest filingsAnnual report (10-K) Mar 24, 2026
    Quarterly report (10-Q) Aug 11, 2026
    Proxy statement (DEF 14A) Apr 22, 2026
    Latest 8-K (8-K) Aug 11, 2026

Securities registered for trading

ClassSymbolExchange
Common Stock. $0.0001 par valueABSIThe Nasdaq Global Select Market

From the cover page of the 10-K filed Mar 24, 2026 (Section 12(b) of the Exchange Act).4

Risk factors and legal proceedings

The risks Absci Corp names in Item 1A of its 10-K filed Mar 24, 2026: 72 risks under these headings, as written.4

  • Risks Related to Our Financial Condition and Need for Additional Capital
  • Our short operating history may make it difficult for you to evaluate the success of our business to date and to assess our future viability.
  • We have incurred significant losses since inception, we expect to incur losses in the future and we may not be able to generate sufficient revenue to achieve and maintain profitability.
  • We will need to raise additional capital to fund our operations, pre-clinical and clinical development of our internally developed programs, and to improve our Integrated Drug Creation platform. If we are unable to raise additional capital on terms acceptable to us or at all, we may not be able to continue to develop our internally developed programs and/or compete successfully with our Integrated Drug Creation platform, which would harm our business, operations, and financial condition.
  • Substantially all of our historical revenue is related to partnered drug creation activities, and we have not demonstrated the ability to enter into a sufficient number of partnerships providing for long-term license arrangements under which we are entitled to receive milestone payments or royalties on net product sales. We have not received any such milestone or royalty revenues to date, and it may be years before we realize any such revenues, if at all.
  • Risks Related to Biologic Drug Development
  • Biologic drug development is inherently uncertain, and it is possible that our technology may not succeed in discovering appropriate product candidates. Even if we do succeed, it is possible that none of the product candidates created using our Integrated Drug Creation platform, if any, that are further developed by our partners will achieve development or regulatory milestones, including marketing approval, or become viable commercial technologies, on a timely basis or at all, which would harm our ability to generate revenue.
  • Positive results from early preclinical studies or preliminary results from clinical trials of our product candidates are not necessarily predictive of the results of later preclinical studies and any future clinical trials of our product candidates. If we cannot replicate the positive results from our earlier preclinical studies of our product candidates in our later preclinical studies, clinical trials and future clinical trials, we may be unable to successfully develop, obtain regulatory approval for and commercialize our product candidates.
  • Preclinical and clinical development is uncertain. Our or our partners' preclinical and clinical product candidates may experience delays or may never advance to and/or through clinical trials, which would adversely affect our or our partners’ ability to obtain regulatory approvals or commercialize these product candidates on a timely basis or at all, which would have an adverse effect on our business.
  • If we or our partners experience any of a number of possible unforeseen or negative events in connection with preclinical or clinical development, regulatory approval or commercialization of product candidates generated through our platform, this could negatively affect our revenue
  • opportunity for that program, and/or have broader deleterious effects on our reputation and future partnership prospects.
  • Preliminary data and interim results we disclose from our clinical trials may change as more data becomes available or as we make changes to our clinical protocols or processes, and such interim results or results from earlier studies may not be predictive of the final results, or of later studies or future clinical trials.
The other 62 risks
  • The clinical development of our product candidates could be substantially delayed if we are required to conduct unanticipated studies, including preclinical studies or clinical trials, or if the FDA imposes other requirements or restrictions including on the manufacture, of our product candidates.
  • We are currently conducting and may in the future conduct clinical trials for our product candidates outside the United States, and the FDA may not accept data from such trials.
  • Conducting clinical trials in Australia may expose us to operational and logistical challenges that could delay our development programs
  • Changes in Australian regulatory requirements or ethics committee processes could delay our clinical trials.
  • If we or our partners encounter difficulties enrolling patients in clinical trials of product candidates developed using our Integrated Drug Creation platform, our and our partners’ clinical development activities could be delayed or otherwise adversely affected.
  • The markets in which we operate, including those for Integrated Drug Creation platform technology and our Internally Developed Programs, are highly competitive, and if we are unable to compete effectively, our business and prospects could be adversely affected..
  • Internally developed programs
  • Integrated Drug Creation platform
  • We face competition from entities that have made substantial investments into the rapid development of novel treatments for the therapeutic indications in which we are engaged in internally developed programs and partnered programs, including large and specialty pharmaceutical and biotechnology companies.
  • The market for our platform, including potential partners and potential investors, may be skeptical of the viability and benefits of our Integrated Drug Creation platform because it is based on novel and complex synthetic biology and AI technologies.
  • We rely and expect to continue to rely on third parties to conduct our preclinical studies and clinical trials. If those third parties do not perform as contractually required, fail to satisfy legal or regulatory requirements, miss expected deadlines or the relationship terminates prematurely, our internally developed programs could be delayed, more costly or unsuccessful, and such programs may never obtain regulatory approval or commercialization.
  • We could experience clinical supply and manufacturing problems that result in delays in the development, approval or commercialization of our product candidates or otherwise harm our business.
  • If we do not achieve our projected development goals in the timeframes we announce and expect, the clinical development of our programs, commercialization of our programs, and validation of our Integrated Drug Creation platform may be delayed and our expenses may increase and, as a result, our stock price may decline.
  • The medical insurance coverage and reimbursement status of newly approved therapeutics is uncertain. Failure to obtain or maintain adequate coverage and reimbursement for current or
  • future products and services could limit our partners’ ability to successfully commercialize product candidates, which would decrease our ability to generate revenue.
  • The pharmaceutical industry is intensely competitive. If we are unable to compete effectively with existing drugs, new treatment methods and new technologies, we may be unable to commercialize successfully any drugs that we develop
  • If we or third parties with whom we do business fail to comply with applicable healthcare laws and regulations, we could be subject to enforcement actions and other consequences.
  • Healthcare reform efforts aimed at lowering the price of biopharmaceutical products may impact our ability to maintain sufficient profits.
  • Existing regulatory policies may change, and additional government regulations may be enacted that could prevent, limit or delay regulatory approval of our product candidates.
  • Disruptions to the operations of the FDA, the SEC or other government agencies, including due to funding shortages, government shutdowns, policy changes or staffing reductions, could delay regulatory reviews, approvals or other governmental actions on which our business depends, which could adversely affect our business.
  • We expect to make significant investments in our continued research and development of new technology, which may not be successful.
  • Risks Related to Our Business Strategy
  • Our commercial success depends on the technological capabilities of our Integrated Drug Creation platform and the advancement of our Internally Developed Programs.
  • We are substantially dependent on the successful application of our Integrated Drug Creation platform to identify, design and advance product candidates for our internally developed programs. Our ability to generate and progress these programs, and in some cases enter into potential collaboration or licensing arrangements for further development, depends in part on the performance and continued development of our platform technologies.
  • Our partnership strategy significantly depends on the eventual approval and commercialization of product candidates developed under our partnerships for which we may have no control over the clinical development plan, regulatory strategy or commercialization efforts.
  • Our revenue under our partnered programs for any particular period, or on an absolute basis, can be difficult to forecast.
  • The failure of our drug creation partners to meet their contractual obligations to us could adversely affect our business.
  • Our partners may not achieve projected discovery and development milestones and other anticipated key events in the expected timelines or at all, which could have an adverse impact on our business and our anticipated revenue.
  • Our partners have significant discretion in determining when and whether to make announcements, if any, about the status of our partnerships, including about clinical developments and timelines for advancing partnered programs, and the price of our common stock may decline as a result of announcements of unexpected or negative results or developments.
  • Risks Related to Our Operations
  • We rely on a limited number of suppliers for laboratory equipment and materials and may not be able to find replacements or transition to alternative suppliers on a timely basis, or at all.
  • Our Integrated Drug Creation platform may not meet the expectations of our partners, which means our business, financial condition, results of operations and prospects could suffer.
  • We may need to develop and expand our workforce, commercial infrastructure and laboratory operations to support anticipated growth in demand for our drug creation programs, and we may encounter difficulties in managing this development and expansion.
  • We have in the past and may in the future need to reduce our workforce, which may not achieve our intended outcomes and could result in unintended consequences.
  • The loss of any member of our senior leadership team or our inability to attract and retain highly skilled scientists and business development professionals could adversely affect our business.
  • We in the past have, and in the future may, make technology acquisitions, acquire businesses or assets, or make investments in other companies or technologies that could negatively affect our operating results, dilute our stockholders’ ownership, increase our debt or cause us to incur significant expense.
  • Our equipment financing agreements may contain covenants that restrict our operating activities, and we may be required to repay the outstanding indebtedness in an event of default, which could have a material adverse effect on our business, financial condition, results of operations and prospects.
  • Our inability to collect on our accounts receivable by a significant number of partners may have an adverse effect on our business, financial condition and results of operations.
  • If our operating facility becomes damaged or inoperable or we are required to vacate our facility, our ability to conduct and pursue our drug creation and internal research and development efforts may be jeopardized.
  • Our current and future use of evolving technologies, such as artificial intelligence (AI), may present risks and challenges that can impact our business, including by posing cybersecurity and other risks to our confidential and/or proprietary information, including personal information, and as a result we may be exposed to operational challenges, reputational harm and potential liability.
  • We depend on our information technology systems, and any significant disruptions to or failure of these systems could result in significant financial, legal, regulatory, business and reputational harm to our business.
  • International expansion of our business exposes us to business, regulatory, political, operational, financial and economic risks associated with doing business outside of the United States.
  • Our business activities are subject to the FCPA and other anti-bribery and anti-corruption laws of the United States and other countries in which we operate, as well as U.S. and certain foreign export controls and trade sanctions. Violations of such legal requirements could subject us to liability.
  • We use biological and hazardous materials that require considerable expertise and expense for handling, storage and disposal and may result in claims against us.
  • Public health crises such as pandemics or similar outbreaks could cause a disruption of the development of our platform technologies, and adversely impact our business.
  • We rely and expect in the future to rely on a limited number of outside parties to perform the cGMP manufacturing for preclinical development, clinical development and commercialization of any biologic product candidates produced using our technology. Limitations in this global cGMP manufacturing capacity could delay or prevent preclinical development, clinical development and/or commercialization efforts.
  • Risks Related to Our Intellectual Property
  • If we are unable to obtain and maintain sufficient intellectual property protection for our technologies and product candidates, or if the scope of the intellectual property protection obtained is not sufficiently broad, our competitors could develop and commercialize technologies or product candidates similar or identical to ours, and our ability to successfully leverage our technologies or product candidates may be impaired.
  • Changes in patent law in the United States and other jurisdictions could diminish the value of patents in general, thereby impairing our ability to protect our technologies.
  • Issued patents covering our Integrated Drug Creation platform and other technologies could be found invalid or unenforceable if challenged.
  • We may come to rely on in-licenses from third parties. If we were to lose these rights, our business could be materially adversely affected, our ability to develop improvements to our Integrated Drug Creation platform or technologies could be negatively and substantially impacted, and if disputes arise, we could be subjected to future litigation as well as the potential loss of or limitations on our ability to incorporate the technology covered by these license agreements.
  • If we cannot acquire or license rights to use technologies on reasonable terms or if we fail to comply with our obligations under such agreements, we may not be able to commercialize new technologies or services in the future and our business could be harmed.
  • We may not be able to protect our intellectual property rights throughout the world.
  • Intellectual property rights do not necessarily address all potential threats to our competitive advantage.
  • If we are unable to protect the confidentiality of our information and our trade secrets, the value of our technologies could be materially adversely affected, and our business could be harmed.
  • We may be subject to claims that our employees, consultants, or independent contractors have wrongfully used or disclosed confidential information of third parties or that our employees have wrongfully used or disclosed alleged trade secrets of their former employers.
  • We are or may become subject to U.S. and foreign laws regarding privacy, data protection, and data security that could require substantial compliance costs, and any failure or perceived failure to comply with them could subject us to significant liability.
  • We may not be able to protect and enforce our trademarks and trade names, or build name recognition in our markets of interest thereby harming our competitive position.
  • We may be subject to claims challenging the inventorship of our patents and other intellectual property.
  • If we become involved in patent litigation or other proceedings related to a determination of rights, we could incur substantial costs and expenses, substantial liability for damages or be required to stop our development and commercialization efforts of our technologies.
  • Obtaining and maintaining our patent protection depends on compliance with various required procedures, document submissions, fee payments and other requirements imposed by
  • governmental patent agencies, and our patent protection could be reduced or eliminated for non-compliance with these requirements.
  • Patent terms may be inadequate to protect our competitive position with our technology for an adequate amount of time.
  • Risks Related to Our Common Stock
  • Our share price may be volatile, and you could lose all or part of your investment.
  • We in the past have had, and in the future may have, a material weakness in our internal control over our financial reporting process. If we are unable to remediate an identified material weakness, we may not be able to accurately or timely report our financial condition or results of operations.
  • We are obligated to develop and maintain proper and effective internal control over financial reporting. These internal controls may not be determined to be effective, which may adversely affect investor confidence in our company and, as a result, the value of our common stock.
  • We have historically identified, and may continue to identify, key business metrics to evaluate our business and technology, measure our performance, identify trends affecting our business, formulate financial projections and make strategic decisions, and any such metrics may not accurately reflect all aspects of our business needed to make such evaluations and decisions, in particular as our business continues to grow.

Legal proceedings

We are not currently a party to any material litigation or other legal proceedings. From time to time, we may, however, in the ordinary course of business face various claims brought by third parties, and we may, from time to time, make claims or take legal actions to assert our rights. Any such claims and associated legal proceedings could, in the opinion of our management, have a material adverse effect on our business, financial condition, results of operations or prospects. Regardless of outcome, litigation can have an adverse impact on us because of defense and settlement costs, diversion of management resources and other factors.

The opening of Item 3, Legal Proceedings.4

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