ACIU on Nasdaq
AC Immune SA
In its 2026 annual report (Form 20-F) the company says: “We are a Swiss stock corporation ( société anonyme ) organized under the laws of Switzerland. Our Swiss enterprise identification number is CHE-109.878.825. Our common shares were admitted to trading on Nasdaq Global Market on September 23, 2016, and trade under the symbol ACIU.”5
$2.44 up 0.04 (1.46%)Price as of Oct 15, 2026 at 17:33 UTC
Last updated Oct 21, 2026.
Overview
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- TickerACIU on Nasdaq1
- IndustryPharmaceutical Preparations1
- HeadquartersV81
- Incorporated inSwitzerland4
- Business addressEpfl Innovation Park, Building B, 1015 Lausanne, V8 000004
- Filer categoryAccelerated filer4
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We are a Swiss stock corporation ( société anonyme ) organized under the laws of Switzerland. We were formed as a Swiss limited liability company ( société à responsabilité limitée ) on February 13, 2003 with our registered office and domicile in Basel, Switzerland. We converted to a Swiss stock corporation ( société anonyme ) under the laws of Switzerland on August 25, 2003. Our Swiss enterprise identification number is CHE-109.878.825. Our domicile and registered office is in Ecublens, at the École Polytechnique Fédérale Lausanne (EPFL) Innovation Park Building B, 1015 Lausanne, Vaud, Switzerland. Our common shares were admitted to trading on Nasdaq Global Market on September 23, 2016, and trade under the symbol ACIU.5 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from. Figures are in CHF, the currency the company reports in.
Key numbers, fiscal 2025
Where the money goes
Where each dollar of revenue went, fiscal 2025
- Research and development100¢56.4M CHF
- Interest0¢191.0K CHF
Out of 3.6M CHF in revenue.3 The company lost money this year.
Financial statements
No quarterly figures reported.
Every line of the income statement as filed: the last 3 fiscal years, latest first.3
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Contract revenue | 3.6M CHF | 27.3M CHF | 14.8M CHF |
| Total revenue | 3.6M CHF | 27.3M CHF | 14.8M CHF |
| Research & development expenses | -56.4M CHF | -62.6M CHF | -54.6M CHF |
| General & administrative expenses | -16.1M CHF | -17.3M CHF | -15.3M CHF |
| Other operating income/(expense), net | 94.0K CHF | 142.0K CHF | 1.5M CHF |
| Restructuring expenses, net | -455.0K CHF | ||
| Total operating expenses | -72.9M CHF | -79.7M CHF | -68.4M CHF |
| Operating loss | -69.3M CHF | -52.4M CHF | -53.6M CHF |
| Financial income | 1.9M CHF | 3.2M CHF | 1.0M CHF |
| Financial expense | -191.0K CHF | -133.0K CHF | -176.0K CHF |
| Exchange differences | -2.8M CHF | -1.6M CHF | -1.5M CHF |
| Finance result, net | -1.1M CHF | 1.5M CHF | -599.0K CHF |
| Loss before tax | -70.4M CHF | -50.9M CHF | -54.2M CHF |
| Income tax expense | 0 CHF | -3.0K CHF | -10.0K CHF |
| Loss for the period | -70.4M CHF | -50.9M CHF | -54.2M CHF |
| Basic loss per share for the period attributable to equity holders | -0.70 CHF | -0.51 CHF | -0.64 CHF |
| Diluted loss per share for the period attributable to equity holders | -0.70 CHF | -0.51 CHF | -0.64 CHF |
No quarter-by-quarter statement was filed.
No quarterly figures reported.
Every line of the balance sheet as filed: the last 4 fiscal years (annual) or 4 quarters (quarterly), latest first.3
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Property, plant and equipment | 2.0M CHF | 2.7M CHF | 3.4M CHF | |
| Right-of-use assets | 4.5M CHF | 5.4M CHF | 3.5M CHF | |
| Intangible asset | 50.4M CHF | 50.4M CHF | ||
| Long-term financial assets | 584.0K CHF | 415.0K CHF | ||
| Total non-current assets | 57.5M CHF | 58.9M CHF | ||
| Prepaid expenses | 4.0M CHF | 4.3M CHF | ||
| Accrued income | 360.0K CHF | 1.1M CHF | ||
| Other current receivables | 978.0K CHF | 1.1M CHF | ||
| Short-term financial assets | 64.6M CHF | 129.2M CHF | ||
| Cash and cash equivalents | 26.8M CHF | 36.3M CHF | 78.5M CHF | 31.6M CHF |
| Total current assets | 96.7M CHF | 172.0M CHF | ||
| Total assets | 154.3M CHF | 230.9M CHF | ||
| Share capital | 2.3M CHF | 2.2M CHF | ||
| Share premium | 481.9M CHF | 478.5M CHF | ||
| Treasury shares | -218.0K CHF | -218.0K CHF | ||
| Currency translation differences | 7.0K CHF | -5.0K CHF | ||
| Accumulated losses | -439.0M CHF | -368.2M CHF | ||
| Total shareholders' equity | 44.9M CHF | 112.3M CHF | 160.6M CHF | 169.0M CHF |
| Long-term deferred contract revenue | 2.3M CHF | 4.6M CHF | ||
| Long-term lease liabilities | 3.7M CHF | 4.4M CHF | ||
| Net employee defined benefit liabilities | 8.6M CHF | 8.8M CHF | ||
| Total non-current liabilities | 14.7M CHF | 17.8M CHF | ||
| Trade and other payables | 2.1M CHF | 2.7M CHF | ||
| Accrued expenses | 8.1M CHF | 12.1M CHF | ||
| Short-term deferred contract revenue | 83.7M CHF | 85.1M CHF | ||
| Short-term lease liabilities | 852.0K CHF | 1.0M CHF | ||
| Total current liabilities | 94.7M CHF | 100.8M CHF | ||
| Total liabilities | 109.4M CHF | 118.6M CHF | ||
| Total shareholders' equity and liabilities | 154.3M CHF | 230.9M CHF |
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Property, plant and equipment | 2.0M CHF | 2.7M CHF | 3.4M CHF | |
| Right-of-use assets | 4.5M CHF | 5.4M CHF | 3.5M CHF | |
| Intangible asset | 50.4M CHF | 50.4M CHF | ||
| Long-term financial assets | 584.0K CHF | 415.0K CHF | ||
| Total non-current assets | 57.5M CHF | 58.9M CHF | ||
| Prepaid expenses | 4.0M CHF | 4.3M CHF | ||
| Accrued income | 360.0K CHF | 1.1M CHF | ||
| Other current receivables | 978.0K CHF | 1.1M CHF | ||
| Short-term financial assets | 64.6M CHF | 129.2M CHF | ||
| Cash and cash equivalents | 26.8M CHF | 36.3M CHF | 78.5M CHF | 31.6M CHF |
| Total current assets | 96.7M CHF | 172.0M CHF | ||
| Total assets | 154.3M CHF | 230.9M CHF | ||
| Share capital | 2.3M CHF | 2.2M CHF | ||
| Share premium | 481.9M CHF | 478.5M CHF | ||
| Treasury shares | -218.0K CHF | -218.0K CHF | ||
| Currency translation differences | 7.0K CHF | -5.0K CHF | ||
| Accumulated losses | -439.0M CHF | -368.2M CHF | ||
| Total shareholders' equity | 44.9M CHF | 112.3M CHF | 160.6M CHF | 169.0M CHF |
| Long-term deferred contract revenue | 2.3M CHF | 4.6M CHF | ||
| Long-term lease liabilities | 3.7M CHF | 4.4M CHF | ||
| Net employee defined benefit liabilities | 8.6M CHF | 8.8M CHF | ||
| Total non-current liabilities | 14.7M CHF | 17.8M CHF | ||
| Trade and other payables | 2.1M CHF | 2.7M CHF | ||
| Accrued expenses | 8.1M CHF | 12.1M CHF | ||
| Short-term deferred contract revenue | 83.7M CHF | 85.1M CHF | ||
| Short-term lease liabilities | 852.0K CHF | 1.0M CHF | ||
| Total current liabilities | 94.7M CHF | 100.8M CHF | ||
| Total liabilities | 109.4M CHF | 118.6M CHF | ||
| Total shareholders' equity and liabilities | 154.3M CHF | 230.9M CHF |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 3 fiscal years, latest first.3
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Loss for the period | -70.4M CHF | -50.9M CHF | -54.2M CHF |
| Depreciation of property, plant and equipment | 1.4M CHF | 1.5M CHF | 1.7M CHF |
| Depreciation of right-of-use assets | 1.1M CHF | 677.0K CHF | 543.0K CHF |
| Finance (income)/expense, net | 803.0K CHF | 57.0K CHF | 922.0K CHF |
| Share-based compensation expense | 4.4M CHF | 5.5M CHF | 4.4M CHF |
| Change in net employee defined benefit liability | -1.6M CHF | -10.0K CHF | 888.0K CHF |
| Interest expense | 189.0K CHF | 131.0K CHF | 176.0K CHF |
| (Gain)/loss on lease modifications | -73.0K CHF | ||
| (Gain)/loss on sale of fixed assets | -15.0K CHF | ||
| (Increase)/decrease in prepaid expenses | 330.0K CHF | 2.1M CHF | -1.7M CHF |
| (Increase)/decrease in accrued income | 739.0K CHF | -853.0K CHF | 162.0K CHF |
| (Increase)/decrease in accounts receivable | 14.8M CHF | -14.8M CHF | |
| (Increase)/decrease in other current receivables | 180.0K CHF | -396.0K CHF | -232.0K CHF |
| (Decrease)/increase in accrued expenses | -3.9M CHF | 1.4M CHF | 1.1M CHF |
| (Decrease)/increase in deferred contract revenue, short-term | -1.4M CHF | 85.1M CHF | |
| (Decrease)/increase in deferred income | -138.0K CHF | -449.0K CHF | |
| (Decrease)/increase in trade and other payables | -592.0K CHF | 977.0K CHF | 770.0K CHF |
| (Decrease)/increase in deferred contract revenue, long-term | -2.2M CHF | 4.6M CHF | |
| Cash provided by/(used in) operating activities | -71.0M CHF | 64.4M CHF | -60.8M CHF |
| Interest received | 1.9M CHF | 1.6M CHF | 595.0K CHF |
| Interest paid | -174.0K CHF | -113.0K CHF | -163.0K CHF |
| Finance expenses paid | -15.0K CHF | -16.0K CHF | -13.0K CHF |
| Net cash flows provided by/(used in) operating activities | -69.3M CHF | 65.8M CHF | -60.4M CHF |
| Short-term financial assets, net | 64.6M CHF | -104.7M CHF | 66.4M CHF |
| Purchases of property, plant and equipment | -900.0K CHF | -576.0K CHF | -801.0K CHF |
| Proceeds from sale of property, plant and equipment | 15.0K CHF | ||
| Rental deposits | -170.0K CHF | -54.0K CHF | 0 CHF |
| Net cash flows provided by/(used in) investing activities | 63.5M CHF | -105.3M CHF | 65.6M CHF |
| Proceeds from public offerings of common shares, net of underwriting fees and transaction costs | 41.1M CHF | ||
| Proceeds from sale of treasury shares in public offerings, net of underwriting fees and transaction costs | 104.0K CHF | 2.7M CHF | |
| Proceeds from issuance of common shares - equity plan, net of transaction costs | 6.0K CHF | 7.0K CHF | 65.0K CHF |
| Transaction costs and stamp duty associated with the public offerings of common shares previously recorded in Accrued expenses | -521.0K CHF | ||
| Transaction costs associated with the sale of treasury shares in public offering previously recorded in Accrued expenses | -27.0K CHF | ||
| Principal payments of lease obligations | -1.0M CHF | -683.0K CHF | -548.0K CHF |
| Net cash flows (used in)/provided by financing activities | -1.0M CHF | -1.1M CHF | 43.2M CHF |
| Net increase/(decrease) in cash and cash equivalents | -6.7M CHF | -40.6M CHF | 48.5M CHF |
| Exchange gain/(loss) on cash and cash equivalents | -2.7M CHF | -1.7M CHF | -1.6M CHF |
| Capital expenditures in Trade and other payables or Accrued expenses | 15.0K CHF | 184.0K CHF | |
| Transaction costs and stamp duty associated with the public offerings of common shares recorded in Accrued expenses | 521.0K CHF | ||
| Transaction costs associated with the sale of treasury shares in public offering recorded in Accrued expenses | 27.0K CHF |
No quarter-by-quarter statement was filed.
Corporate structure
AC Immune SA sits at the top of its group. 1 entity on record. Switch between the flow chart and the network, and select any entity to see its details.
Major holders of AC Immune SA
- AFFIRIS AG in Liqu Filed SC 13G/A on AC Immune SA, latest Dec 13, 2024 (3 filings since Feb 14, 2023)
- BIOTECHNOLOGY VALUE FUND L P Filed SC 13G/A on AC Immune SA, latest Nov 14, 2024 (4 filings since Feb 14, 2022)
- dievini Hopp BioTech holding GmbH & Co KG Filed SC 13G/A on AC Immune SA, latest Feb 10, 2023
- Eli Lilly and Company Filed SC 13G/A on AC Immune SA, latest Jan 27, 2023
- EcoR1 Capital, LLC Filed SC 13G/A on AC Immune SA, latest Feb 14, 2022
- AC Immune SA V8
Built from major holders from Schedules 13D and 13G. Each entity in the chart links to its source.
What it owns
What AC Immune SA reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.
Property and equipment
| Item | Latest | A year before | Change |
|---|---|---|---|
| Property and equipment, net | 2.0M CHF3 Dec 31, 2025 | 2.7M CHF3 Dec 31, 2024 | −25.0% |
| Operating-lease assets (leased space) | 4.5M CHF3 Dec 31, 2025 | 5.4M CHF3 Dec 31, 2024 | −16.5% |
Investments
| Item | Latest | A year before | Change |
|---|---|---|---|
| Cash and cash equivalents | 26.8M CHF3 Dec 31, 2025 | 36.3M CHF3 Dec 31, 2024 | −26.1% |
Intangibles and goodwill
Leadership
Who has led AC Immune SA, and when. Pick a name to see everywhere that person has worked.
Chief executive
Chief operating officer
- Chief executive officerAndrea Pfeifer Mar 18, 2026 to Jun 15, 202612
- Chief executive officerMartin Zuegel Jun 15, 2026 to now13
- Chief operating officerPiergiorgio Donati Mar 20, 2026 to now14
Board members and other officers (6)
- Board memberAndrea Pfeifer Mar 18, 2026 to now12
- Board memberCarl Howard June Mar 18, 2026 to now15
- Board memberMonika Buetler Mar 18, 2026 to now16
- Board memberRenee Aguiar-Lucander Mar 18, 2026 to now17
- Board memberRoy Ervin Twyman Mar 18, 2026 to now18
- Board memberMartin Zuegel Apr 1, 2026 to now19
Timeline
Calendar
Coming up
- Nov 3, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported ($0.20) a share, on Nov 4, 2025.20
Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar
Filings
143 filings to the SEC since October 2021: 5 annual reports, 18 insider forms, 10 large holders, 110 other. The latest 20:
- Oct 9, 20263 PRIMARY DOCUMENT EDGAR
- Oct 9, 20263/A EDGAR
- Oct 2, 20266-K EDGAR
- Sep 23, 20266-K EDGAR
- Sep 3, 20266-K EDGAR
- Aug 20, 20266-K EDGAR
- Aug 11, 20266-K EDGAR
- Aug 5, 20266-K EDGAR
- Jun 30, 20266-K EDGAR
- Jun 15, 20264 PRIMARY DOCUMENT EDGAR
- Jun 15, 20264 PRIMARY DOCUMENT EDGAR
- Jun 15, 20264 PRIMARY DOCUMENT EDGAR
- Jun 15, 20264 PRIMARY DOCUMENT EDGAR
- Jun 15, 20264 PRIMARY DOCUMENT EDGAR
- Jun 11, 20266-K EDGAR
- Jun 11, 20266-K EDGAR
- May 18, 20264 PRIMARY DOCUMENT EDGAR
- May 15, 2026144 EDGAR
- May 15, 20266-K EDGAR
- May 12, 20266-K EDGAR
The 143 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
3 open-market trades by officers, directors and large owners since October 2021: 1 buys and 2 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| May 15, 2026 | Pfeifer AndreaChief Executive Officer | Sale | 10,000 | $2.79 | $27.9K | Form 4 |
| Apr 15, 2026 | Pfeifer AndreaChief Executive Officer | Sale | 10,000 | $3.14 | $31.4K | Form 4 |
| Apr 15, 2026 | Pfeifer AndreaChief Executive Officer | Buy | 10,000 | $3.14 | $31.4K | Form 4 |
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- AFFIRIS AG in LiquSC 13G/A, 3 filings Feb 14, 2023 to Dec 13, 202421
- BIOTECHNOLOGY VALUE FUND L PSC 13G/A, 4 filings Feb 14, 2022 to Nov 14, 202422
- dievini Hopp BioTech holding GmbH & Co KGSC 13G/A, 1 filing Feb 10, 202323
- Eli Lilly and CompanySC 13G/A, 1 filing Jan 27, 202324
- EcoR1 Capital, LLCSC 13G/A, 1 filing Feb 14, 202225
SEC filer profile
How AC Immune SA is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.
- Name on EDGARAC Immune SA1
- CIK0001651625
- Filer statusAccelerated filer not an emerging growth company; not a shell company5
- Incorporated inSwitzerland5
- Fiscal year endsDecember 311
- Industry code (SIC)2834 Pharmaceutical Preparations1
- SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
- Business addressEpfl Innovation Park, Building B, 1015 Lausanne, V8 000001
- Phone41 21 345 91 211
- Shares outstanding101,742,231 shares as of Dec 31, 20255
- AuditorPricewaterhouseCoopers SA, Lausanne, Switzerland PCAOB ID 1358; it also attests to the company’s internal control over financial reporting5
- On EDGAR sinceAug 28, 20151
- Filings312 in all: 6-K (143), 144 (28), SC 13G/A (23), CORRESP (17), UPLOAD (16), 20-F (10), 3 (9), 424B5 (8)1
All 28 form types
SC 13G (8), 4 (7), F-1/A (7), EFFECT (6), DRS/A (5), F-3 (5), DRSLTR (3), S-8 (3), F-3/A (2), FWP (2), 20-F/A (1), 3/A (1), 4/A (1), 424B4 (1), 6-K/A (1), 8-A12B (1), CERTNAS (1), CT ORDER (1), DRS (1), F-1 (1)
- Latest filingsAnnual report (20-F) Mar 13, 2026
Securities registered for trading
| Class | Symbol | Exchange |
|---|---|---|
| Common Shares, nominal value CHF 0.02 per share | ACIU | The Nasdaq Stock Market LLC |
From the cover page of the 20-F filed Mar 13, 2026 (Section 12(b) of the Exchange Act).5
Sources
The numbers on this page point here. Each one links to the record it came from.
- 1SEC EDGARAC Immune SA filings on SEC EDGAR
- 2Yahoo FinanceACIU quote
- 3SEC EDGARAC Immune SA 10-K for fiscal 2025
- 4SEC EDGARAC Immune SA filings on SEC EDGAR
- 5
- 6SEC EDGARAC Immune SA 10-K for fiscal 2018
- 7SEC EDGARAC Immune SA 10-K for fiscal 2019
- 8SEC EDGARAC Immune SA 10-K for fiscal 2020
- 9SEC EDGARAC Immune SA 10-K for fiscal 2021
- 10SEC EDGARAC Immune SA 10-K for fiscal 2022
- 11SEC EDGARAC Immune SA 10-K for fiscal 2018
- 12
- 13
- 14
- 15SEC EDGARCarl Howard June, Board member
- 16SEC EDGARMonika Buetler, Board member
- 17SEC EDGARRenee Aguiar-Lucander, Board member
- 18SEC EDGARRoy Ervin Twyman, Board member
- 19SEC EDGARMartin Zuegel, Board member
- 20NasdaqNasdaq calendar
- 21
- 22
- 23
- 24
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