Overview
- TickerAKTX on Nasdaq2
- IndustryPharmaceutical Preparations2
- HeadquartersWeybridge, United Kingdom2
- Incorporated inUnited Kingdom4
- Business address401 East Jackson Street, Suite 3300, Tampa, Fl 336024
- Filer categoryNon-accelerated filer, Smaller reporting company4
- Legal formOther2
- LEI2138001XURASAU3MEB682
- StatusActive2
- LEI statusLapsed (not renewed)2
- Registered addressELDER HOUSE, ST GEORGES BUSINESS PARK, KT13 0TS Weybridge, United Kingdom2
- Registered withCompanies House, 052528422
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Cancer Society estimates that approximately 626,000 people will die of cancer in the United States in 2026.6 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.11
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Research and development | $2.8M | $7.0M |
| General and administrative | $9.3M | $9.7M |
| Impairment loss on other intangible assets | $5.2M | |
| Merger-related expenses | $3.3M | |
| Restructuring and other expenses | $1.7M | |
| Total operating expenses | $17.3M | $21.6M |
| Loss from operations | -$17.3M | -$21.6M |
| Interest income | $1.0K | $8.0K |
| Interest expense | -$949.0K | -$244.0K |
| Gain on settlement of current liabilities | $3.0M | |
| Loss on debt extinguishment | -$3.2M | |
| Change in fair value of warrant liabilities | $775.0K | $2.1M |
| Loss on derivative liability | -$230.0K | |
| Foreign currency exchange gains (losses), net | -$443.0K | $6.0K |
| Other expense, net | -$3.0K | |
| Total other income, net | -$1.0M | $1.9M |
| Net loss before income taxes | -$18.3M | -$19.8M |
| Income tax benefit | $1.0M | |
| Net loss | -$17.3M | -$19.8M |
| Net loss per share - basic | $0.00 | $0.00 |
| Net loss per share - diluted | $0.00 | $0.00 |
| Weighted-average number of Ordinary Shares used in computing net loss per share - basic | 67.3B shares | 23.9B shares |
| Weighted-average number of Ordinary Shares used in computing net loss per share - diluted | 67.3B shares | 23.9B shares |
| Foreign currency translation adjustment | -$44.0K | $302.0K |
| Total other comprehensive income, net of tax | -$44.0K | $302.0K |
| Total comprehensive loss | -$17.3M | -$19.5M |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 4 fiscal years (annual) or 4 quarters (quarterly), latest first.11
| Period ending | 2025-12-31 | 2025-11-30 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|---|
| Cash | $5.2M | $2.6M | ||
| Restricted cash | $60.0K | $60.0K | ||
| Prepaid expenses | $185.0K | $92.0K | ||
| Other current assets | $14.0K | $201.0K | ||
| Total current assets | $5.5M | $3.0M | ||
| Goodwill | $8.4M | $8.4M | ||
| Other intangible assets | $34.0M | $39.2M | ||
| Total assets | $47.9M | $50.6M | ||
| Accounts payable | $8.8M | $12.4M | ||
| Accrued expenses | $2.3M | $3.1M | ||
| Convertible notes, net | $673.0K | $700.0K | ||
| Convertible notes, related party | $250.0K | |||
| Notes payable, net | $81.0K | $659.0K | ||
| Notes payable, related party | $1.7M | |||
| Warrant liabilities | $61.0K | $1.0M | ||
| Other current liabilities | $424.0K | $94.0K | ||
| Total current liabilities | $12.4M | $19.9M | ||
| Derivative liability | $230.0K | |||
| Other non-current liabilities | $31.0K | $383.0K | ||
| Deferred tax liability | $7.0M | $8.0M | ||
| Total liabilities | $19.6M | $28.3M | ||
| Share capital of $0.000000005 par value Authorized: 761,963,201,733 and 245,035,791,523 ordinary shares at December 31, 2025 and December 31, 2024, respectively; issued and outstanding: 90,536,879,533 and 53,186,919,523 ordinary shares at December 31, 2025 and December 31, 2024, respectively | $5.3M | |||
| Additional paid-in capital | $234.3M | $212.7M | ||
| Capital redemption reserve | $59.3M | $52.2M | ||
| Accumulated other comprehensive loss | -$782.0K | -$738.0K | ||
| Accumulated deficit | -$264.6M | -$247.3M | ||
| Total shareholders equity | $28.3M | $22.2M | -$229.0K | |
| Total liabilities and shareholders equity | $47.9M | $50.6M | ||
| Ordinary shares, par value | $0.00 | $0.00 | $0.00 | |
| Ordinary shares, shares authorized | 762.0B shares | 762.0B shares | 245.0B shares | |
| Ordinary shares, shares issued | 90.5B shares | 53.2B shares | ||
| Ordinary shares, shares outstanding | 90.5B shares | 53.2B shares |
| Period ending | 2025-12-31 | 2025-11-30 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|---|
| Cash | $5.2M | $2.6M | ||
| Restricted cash | $60.0K | $60.0K | ||
| Prepaid expenses | $185.0K | $92.0K | ||
| Other current assets | $14.0K | $201.0K | ||
| Total current assets | $5.5M | $3.0M | ||
| Goodwill | $8.4M | $8.4M | ||
| Other intangible assets | $34.0M | $39.2M | ||
| Total assets | $47.9M | $50.6M | ||
| Accounts payable | $8.8M | $12.4M | ||
| Accrued expenses | $2.3M | $3.1M | ||
| Convertible notes, net | $673.0K | $700.0K | ||
| Convertible notes, related party | $250.0K | |||
| Notes payable, net | $81.0K | $659.0K | ||
| Notes payable, related party | $1.7M | |||
| Warrant liabilities | $61.0K | $1.0M | ||
| Other current liabilities | $424.0K | $94.0K | ||
| Total current liabilities | $12.4M | $19.9M | ||
| Derivative liability | $230.0K | |||
| Other non-current liabilities | $31.0K | $383.0K | ||
| Deferred tax liability | $7.0M | $8.0M | ||
| Total liabilities | $19.6M | $28.3M | ||
| Share capital of $0.000000005 par value Authorized: 761,963,201,733 and 245,035,791,523 ordinary shares at December 31, 2025 and December 31, 2024, respectively; issued and outstanding: 90,536,879,533 and 53,186,919,523 ordinary shares at December 31, 2025 and December 31, 2024, respectively | $5.3M | |||
| Additional paid-in capital | $234.3M | $212.7M | ||
| Capital redemption reserve | $59.3M | $52.2M | ||
| Accumulated other comprehensive loss | -$782.0K | -$738.0K | ||
| Accumulated deficit | -$264.6M | -$247.3M | ||
| Total shareholders equity | $28.3M | $22.2M | -$229.0K | |
| Total liabilities and shareholders equity | $47.9M | $50.6M | ||
| Ordinary shares, par value | $0.00 | $0.00 | $0.00 | |
| Ordinary shares, shares authorized | 762.0B shares | 762.0B shares | 245.0B shares | |
| Ordinary shares, shares issued | 90.5B shares | 53.2B shares | ||
| Ordinary shares, shares outstanding | 90.5B shares | 53.2B shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.11
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$17.3M | -$19.8M |
| Depreciation and amortization | $14.0K | |
| Stock-based compensation | $2.9M | $2.2M |
| Issuance of shares for services | $27.0K | $271.0K |
| Accretion of debt issuance costs | $589.0K | |
| Gain on settlement of current liabilities | -$3.0M | |
| Loss on debt extinguishment | $3.2M | |
| Change in fair value of warrant liabilities | -$775.0K | -$2.1M |
| Impairment loss on other intangible assets | $5.2M | |
| Loss on derivative liability | $230.0K | |
| Deferred income tax benefit | -$1.1M | |
| Unrealized foreign currency exchange losses (gains) | -$99.0K | $255.0K |
| Prepaid expenses and other current assets | $594.0K | $1.3M |
| Accounts payable and accrued expenses | -$998.0K | $5.2M |
| Net cash used in operating activities | -$10.6M | -$12.6M |
| Cash acquired in Peak Bio Acquisition | $382.0K | |
| Net cash provided by investing activities | $382.0K | |
| Proceeds from issuance of shares, net of issuance costs | $10.7M | $11.8M |
| Proceeds from issuance of warrants | $1.0M | |
| Proceeds from issuance of notes payable | $2.1M | |
| Proceeds from issuance of convertible notes | $1.0M | |
| Repayment of notes payable and convertible notes | -$553.0K | -$750.0K |
| Proceeds from issuance of restricted shares | $26.0K | |
| Proceeds from employee vesting of restricted shares | $33.0K | $2.0K |
| Proceeds from pre-funded warrants | $330.0K | |
| Payments on seller-financed purchases | -$499.0K | -$1.1M |
| Net cash provided by financing activities | $13.2M | $11.0M |
| Effect of exchange rates on cash | $1.0K | -$4.0K |
| Net change in cash | $2.6M | -$1.2M |
| Financing costs in accounts payable and accrued expenses | $348.0K | |
| Seller-financed purchases | $499.0K | $1.1M |
| Issuance of share capital for settlement of convertible notes, related party | $309.0K | |
| Issuance of share capital for settlement of related party debt | $1.0M | |
| Issuance of share capital for payments in kind | $595.0K | |
| Modification of warrants in connection with issuance of notes payable | $2.6M | |
| Modification of warrants in connection with amendment of convertible notes | $192.0K | |
| Issuance of warrants in connection with note exchange and cancellation | $4.0M | |
| Payroll taxes on stock-based compensation in accrued expenses | $193.0K | |
| Issuance of ordinary shares for Peak Bio Acquisition | $28.1M | |
| Warrants assumed in connection with Peak Bio Acquisition | $1.8M | |
| Cash paid for interest | $101.0K | $143.0K |
No quarter-by-quarter statement was filed.
Corporate structure
Akari Therapeutics Plc sits at the top of its group. 8 entities, 6 countries on record. Switch between the flow chart and the network, and select any entity to see its details.
Major holders of Akari Therapeutics Plc
- Bank of Montreal Filed SCHEDULE 13G on Akari Therapeutics Plc, latest Aug 12, 2026
- White Lion Capital LLC Filed SCHEDULE 13G on Akari Therapeutics Plc, latest Aug 7, 2026
- MMCAP International Inc. SPC Filed SCHEDULE 13G on Akari Therapeutics Plc, latest Jun 8, 2026
- Hoyoung Huh Filed SCHEDULE 13G/A on Akari Therapeutics Plc, latest Mar 4, 2026 (2 filings since Feb 14, 2025)
- Ray Prudo Filed SCHEDULE 13D/A on Akari Therapeutics Plc, latest Mar 4, 2026 (2 filings since Feb 14, 2025)
- Samir Rashmikant Patel Filed SCHEDULE 13D/A on Akari Therapeutics Plc, latest Mar 4, 2026 (5 filings since Feb 14, 2022)
- RPC Pharma Ltd Filed SC 13D/A on Akari Therapeutics Plc, latest Jun 20, 2024 (6 filings since Oct 18, 2021)
- Charles Steve Theofilos Filed SC 13D on Akari Therapeutics Plc, latest Jun 18, 2024
- Akari Therapeutics Plc Weybridge, United Kingdom
- Akari Malta Limited Subsidiary · Malta
- Celsus Therapeutics Inc. Subsidiary · Delaware, United States
- Ignyte Korea Co., Ltd. Subsidiary · South Korea
- Morria Biopharma Ltd. Subsidiary · Israel
- Peak Bio CA, Inc. Subsidiary · California, United States
- Peak Bio Co., Ltd. Subsidiary · South Korea
- Volution Immuno Pharmaceuticals SA Subsidiary · Switzerland
Built from parent and subsidiary links from GLEIF, the Global Legal Entity Identifier Foundation (CC0); subsidiaries listed in Exhibit 21 of annual reports filed with the SEC; major holders from Schedules 13D and 13G. Each entity in the chart links to its source.
What it owns
What Akari Therapeutics Plc reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.
Investments
Intangibles and goodwill
Properties, in its own words
We currently lease office space for both our U.S. headquarters and U.S laboratory space on a short-term basis. The lease for our U.S. headquarters office space, located in Tampa, FL, expires September 2026 and may be renewed on a month-to-month basis thereafter. We also lease laboratory space, located in San Francisco, CA, which expires in September 2026 and is cancellable anytime with 60 days’ notice. We are not party to any material lease agreements. We believe that our current facilities are adequate to meet our needs and that suitable additional alternative spaces will be available in the future on commercially reasonable terms, if required.
Item 2 of the 10-K filed Mar 30, 2026.6
Leadership
Who has led Akari Therapeutics Plc, and when. Pick a name to see everywhere that person has worked.
President
Chief financial officer
Chief operating officer
- Chief executive officerAbizer Gaslightwala Jun 12, 2025 to now16
- Chief executive officerRachelle Suzanne Jacques Jan 2, 2024 to Apr 30, 202417
- Chief executive officerGur Roshwalb Jan 2, 2015 to Sep 22, 201518
- PresidentAbizer Gaslightwala Jun 20, 2025 to now19
- Chief financial officerKameel D. Farag Oct 24, 2025 to now20
- Chief financial officerWendy F. Dicicco Jan 2, 2024 to May 3, 202421
- Chief financial officerTorsten Hombeck Dec 20, 2024 to Oct 24, 202522
- Chief financial officerDov Elefant Jan 2, 2015 to Sep 22, 201523
- Chief operating officerClive Richardson Sep 23, 2015 to Sep 23, 201524
Board members and other officers (20)
- Chief Medical OfficerPablo Jimenez Jan 2, 2015 to Jan 2, 201525
- Board memberDonald A. Williams Jan 2, 2024 to Jul 2, 202426
- Board memberMichael Grissinger Jan 2, 2024 to Jul 2, 202427
- Board memberMohamed Wa'El Ahmed Hashad Jan 2, 2024 to Jul 2, 202428
- Board memberRachelle Suzanne Jacques Jan 2, 2024 to Apr 30, 202417
- Board memberRobert B. Bazemore Sep 18, 2024 to now29
- Board memberHoyoung Huh Nov 22, 2024 to now30
- Board memberJames R. Neal Nov 22, 2024 to now31
- Board memberSandip I. Patel Nov 22, 2024 to now32
- Board memberAbizer Gaslightwala Dec 26, 2024 to now33
- Board memberAllan Shaw Jan 2, 2015 to Nov 25, 201534
- Board memberAimos Eiran Jan 2, 2015 to Jan 2, 201535
- Board memberDavid Sidransky Jan 2, 2015 to Jan 2, 201536
- Board memberGur Roshwalb Jan 2, 2015 to Sep 22, 201518
- Board memberJohnson Yiu Nam Lau Jan 2, 2015 to Jan 2, 201537
- Board memberRobert F. Doman Jan 2, 2015 to Jan 2, 201538
- Board memberClive Richardson Sep 23, 2015 to Sep 23, 201524
- Board memberRay Prudo Sep 23, 2015 to now39
- Board memberStuart Ungar Sep 23, 2015 to Jun 30, 201640
- General counselRobert M. Shaw Mar 25, 2016 to Mar 25, 201641
Named in SEC Form D filings
People the company listed in its private-offering notices.
Subsidiaries and ownership
Subsidiaries (Exhibit 21)
- Akari Malta Limited Malta5
- Celsus Therapeutics Inc. Delaware5
- Ignyte Korea Co., Ltd. Republic of Korea5
- Morria Biopharma Ltd. Israel5
- Peak Bio CA, Inc. California5
- Peak Bio Co., Ltd. Republic of Korea5
- Peak Bio Inc. Delaware5
- Volution Immuno Pharmaceuticals SA Switzerland5
The subsidiaries the company lists in Exhibit 21 of its annual report, as filed.
Former names
Timeline
- Oct 1, 20268-K Executive or director change45
- Aug 13, 20268-K Results of operations46
- Jul 2, 20268-K Shareholder vote47
- Jun 26, 20268-K Entered a material agreement48
- May 22, 20268-K Entered a material agreement; Unregistered sale of shares49
- Mar 17, 20268-K Change to shareholders' rights; Regulation FD disclosure50
- Mar 2, 20268-K Shareholder vote51
- Dec 17, 20258-K Entered a material agreement; Ended a material agreement; Unregistered sale of shares52
- Dec 16, 20258-K Shareholder vote53
- Dec 8, 20258-K Regulation FD disclosure54
- Nov 26, 20258-K Listing notice or transfer55
- Oct 23, 20258-K Executive or director change56
- Jun 12, 2025New chief executive Abizer Gaslightwala becomes CEO16
- Jan 2, 2024New chief executive Rachelle Suzanne Jacques becomes CEO17
- Jan 2, 2015New chief executive Gur Roshwalb becomes CEO18
Calendar
Coming up
- Nov 12, 2026Reports results for the quarter ending Sep/202657
When it reported results
- Aug 13, 2026Reported quarterly or annual results46
- May 15, 2025Reported quarterly or annual results58
- Apr 16, 2025Reported quarterly or annual results59
- Aug 19, 2024Reported quarterly or annual results60
- May 16, 2024Reported quarterly or annual results61
- Apr 1, 2024Reported quarterly or annual results62
Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar
Filings
321 filings to the SEC since October 2021: 5 annual reports, 8 quarterly reports, 46 major events, 81 insider forms, 19 large holders, 5 private raises, 157 other. The latest 20:
- Oct 14, 20264 EDGAR
- Oct 14, 20263 EDGAR
- Oct 1, 2026DEF 14A EDGAR
- Oct 1, 20264 EDGAR
- Oct 1, 20268-K EDGAR
- Aug 19, 20264 EDGAR
- Aug 13, 20268-K EDGAR
- Aug 13, 202610-Q EDGAR
- Aug 12, 2026SCHEDULE 13G EDGAR
- Aug 7, 2026SCHEDULE 13G EDGAR
- Aug 5, 20264 EDGAR
- Jul 17, 20264 EDGAR
- Jul 13, 2026EFFECT EDGAR
- Jul 10, 2026S-3/A EDGAR
- Jul 8, 2026S-3/A EDGAR
- Jul 7, 2026EFFECT EDGAR
- Jul 2, 20268-K EDGAR
- Jul 2, 2026S-3 EDGAR
- Jun 26, 20268-K EDGAR
- Jun 26, 2026S-1/A EDGAR
The 321 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
7 open-market trades by officers, directors and large owners since October 2021: 7 buys and 0 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Aug 25, 2025 | Gaslightwala AbizerCEO | Buy | 3,000 | $0.90 | $2.7K | Form 4 |
| Aug 22, 2025 | Gaslightwala AbizerCEO | Buy | 8,000 | $0.93 | $7.4K | Form 4 |
| Aug 21, 2025 | Gaslightwala AbizerCEO | Buy | 10,000 | $0.94 | $9.4K | Form 4 |
| Jun 24, 2025 | Gaslightwala AbizerCEO | Buy | 5,203 | $1.16 | $6.0K | Form 4 |
| Jun 23, 2025 | Gaslightwala AbizerCEO | Buy | 943 | $1.15 | $1.1K | Form 4 |
| Jun 20, 2025 | Gaslightwala AbizerCEO | Buy | 10,000 | $1.20 | $12.0K | Form 4 |
| Jun 17, 2025 | Gaslightwala AbizerCEO | Buy | 15,000 | $1.20 | $18.0K | Form 4 |
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- Bank of MontrealSCHEDULE 13G, 1 filing Aug 12, 202663
- White Lion Capital LLCSCHEDULE 13G, 1 filing Aug 7, 202664
- MMCAP International Inc. SPCSCHEDULE 13G, 1 filing Jun 8, 202665
- Hoyoung HuhSCHEDULE 13G/A, 2 filings Feb 14, 2025 to Mar 4, 202666
- Ray PrudoSCHEDULE 13D/A, 2 filings Feb 14, 2025 to Mar 4, 202667
- Samir Rashmikant PatelSCHEDULE 13D/A, 5 filings Feb 14, 2022 to Mar 4, 202668
- RPC Pharma LtdSC 13D/A, 6 filings Oct 18, 2021 to Jun 20, 202469
- Charles Steve TheofilosSC 13D, 1 filing Jun 18, 202470
Funding
Where the company's money came from, by calendar year: private offerings filed with the SEC, federal grants, loans, contracts and other assistance from USAspending.gov, and PPP loans from the SBA. Each bar links to the records below.
- Private raises (Form D) $24.9M
Figures by year
| Year | Private raises (Form D) | Total |
|---|---|---|
| 2026 | $1.8M | $1.8M |
| 2025 | $6.2M | $6.2M |
| 2023 | $4.0M | $4.0M |
| 2022 | $12.8M | $12.8M |
Private raises
Private offerings the company reported to the SEC on Form D. The amount is what the latest filing says was sold so far, charted in the year of the first sale. Covers filings since Oct 1, 2021.
- May 20, 2026Raised $1.8 million in a private offering of securities43 Form D: $5.5 million offered in all Form D
- Oct 16, 2025Raised $6.2 million in a private offering of securities71 Form D: 4 investors so far Form D
- Dec 27, 2023Raised $2 million in a private offering of equity44 Form D: 2 investors so far Form D
- Oct 4, 2023Raised $2 million in a private offering of equity72 Form D: 11 investors so far Form D
- Sep 14, 2022Raised $12.8 million in a private offering of securities42 Form D: 21 investors so far Form D
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| MMCAP International Inc. SPC | 100,000 | $1.0M | 0.1% | New |
| Cresset Asset Management, LLC | 20,561 | $210.6K | 0.0% | No change |
| Jane Street Group, LLC | 15,463 | $158.4K | 0.0% | New |
| IFP Advisors, Inc | 181 | $1.9K | 0.0% | No change |
| SBI Securities Co., Ltd. | 14 | $143 | 0.0% | +9 |
| Hrt Financial LP | 13,745 | $140 | 0.0% | New |
| Caitong International Asset Management Co., Ltd | 8 | $82 | 0.0% | New |
| Northwestern Mutual Wealth Management Co | 7 | $72 | 0.0% | New |
| Truvestments Capital LLC | 1 | $10 | 0.0% | No change |
13F reports cover disclosed long positions in U.S. stocks only.
SEC filer profile
How Akari Therapeutics Plc is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.
- Name on EDGARAkari Therapeutics Plc1
- CIK0001541157
- Employer ID (EIN)98-10349226
- Filer statusNon-accelerated filer not an emerging growth company; a smaller reporting company; a shell company6
- Incorporated inEngland and Wales6
- Fiscal year endsDecember 311
- Industry code (SIC)2834 Pharmaceutical Preparations1
- SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
- Business address401 East Jackson Street, Suite 3300, Tampa, FL 336021
- Phone(929) 274-75101
- Shares outstanding155,758,529,533 as of Aug 13, 202613
- Public float$15.0M as of Jun 30, 20256
- AuditorBDO USA, P.C., New York, New York PCAOB ID 243; no auditor attestation of internal control over financial reporting6
- On EDGAR sinceApr 13, 20121
- Filings735 in all: 6-K (188), 4 (91), 8-K (62), EFFECT (50), 3 (33), POS AM (25), UPLOAD (25), CORRESP (23)1
All 59 form types
424B3 (22), SC 13G/A (19), D (13), 10-Q (12), DEFA14A (11), 424B5 (10), SC 13G (10), 20-F (9), F-1 (9), F-1/A (9), SC 13D/A (9), DEF 14A (8), 425 (6), F-3 (6), S-8 (6), 10-K (5), S-1 (5), S-3 (5), 20FR12G/A (4), NT 10-Q (4), PRE 14A (4), SCHEDULE 13G (4), ARS (3), F-3/A (3), F-6 POS (3), RW (3), SC 13D (3), SCHEDULE 13D/A (3), 20-F/A (2), 20FR12G (2), 8-K/A (2), F-6EF (2), NT 20-F (2), S-3/A (2), S-4/A (2), 4/A (1), 424B2 (1), 424B4 (1), 6-K/A (1), 8-A12B (1), CERTNAS (1), D/A (1), DEFM14A (1), DRS (1), F-6 (1), F-6/A (1), NT 10-K (1), PREM14A (1), S-1/A (1), S-4 (1), SCHEDULE 13G/A (1)
- Latest filingsAnnual report (10-K) Mar 30, 2026
Quarterly report (10-Q) Aug 13, 2026
Proxy statement (DEF 14A) Oct 1, 2026
Latest 8-K (8-K) Oct 1, 2026
Securities registered for trading
| Class | Symbol | Exchange |
|---|---|---|
| American Depository Shares, each representing 2,000 Ordinary Shares, par value $0.000000005 per share | AKTX | Nasdaq |
| Ordinary Shares, $0.000000005 par value per share* | AKTX | Nasdaq |
From the cover page of the 10-K filed Mar 30, 2026 (Section 12(b) of the Exchange Act).6
Risk factors and legal proceedings
The risks Akari Therapeutics Plc names in Item 1A of its 10-K filed Mar 30, 2026: 51 risks under these headings, as written.6
- Risks Related to Our Financial Position and Our Capital Requirements
- We have a history of operating losses and cannot give assurance of future revenues or operating profits.
- We will require substantial additional capital to fund our operations, and if we are unable to obtain such capital, we will be unable to successfully develop and commercialize any product candidates.
- Raising additional capital may cause significant dilution to our shareholders or restrict our operations.
- Our ability to use net operating losses to offset future income may be subject to certain limitations.
- We have identified material weaknesses in our internal control over financial reporting. If our remediation of the material weaknesses are not effective, or if we experience additional material weaknesses in the future or otherwise fail to maintain an effective system of internal controls in the future, we may not be able to accurately or timely report our financial condition or results of operations, which may adversely affect investor confidence in us and, as a result, the value of our ADSs.
- Risks Related to Discovery, Development and Regulatory Approval of Our Product Candidates
- We have not initiated clinical studies for any of the programs in our active pipeline or entered into any strategic partnerships regarding the continued development of our legacy pipeline assets. As a result, it may be years before we commercialize a product candidate, if ever. If we, alone or with a strategic partner, are unable to identify and advance product candidates through preclinical studies and clinical trials, obtain marketing approval and ultimately commercialize them, or experience significant delays in doing so, our business will be materially harmed.
- Preclinical and clinical drug development is a lengthy and expensive process, with uncertain timelines and outcomes. If preclinical studies or clinical trials of our product candidates are prolonged or delayed, we may be unable to obtain required regulatory approvals and therefore be unable to commercialize our product candidates or any of our future product candidates on a timely basis or at all.
- We may encounter substantial delays in the commencement, enrollment or completion of clinical trials or we may fail to demonstrate safety and efficacy to the satisfaction of applicable regulatory authorities, which could prevent us from commercializing any product candidates we determine to develop on a timely basis, if at all.
- Serious adverse events, undesirable side effects or other unexpected properties of our product candidates may be identified during development or after approval, which could lead to the discontinuation of our development programs, refusal by regulatory authorities to approve our product candidates or, if discovered following marketing approval, revocation of marketing authorizations or limitations on the use of our product candidates, any of which would limit the commercial potential of such product candidates.
- Our proprietary ADC Platform is based on novel technologies that are unproven and may not result in approvable or marketable products, which exposes us to unforeseen risks and makes it difficult for us to predict the time and cost of product development and potential for regulatory approval, and we may not be successful in our efforts to expand our development portfolio of product candidates.
The other 41 risks
- Interim, initial, or preliminary results from our preclinical testing or clinical trials that we announce or publish from time to time may change as more patient data become available and are subject to additional audit, validation and verification procedures that could result in material changes in the final data.
- We or a future strategic partner may choose to, or may be required to, suspend, repeat, or terminate clinical trials of our assets if they are not conducted in accordance with regulatory requirements, the results are negative or inconclusive or the trials are not well designed.
- Our employees, independent contractors, principal investigators, contract research organizations, consultants, vendors and collaboration partners may engage in misconduct or other improper activities, including non-compliance with regulatory standards.
- Risks Related to Commercialization, Marketing and Competition
- Our industry is highly competitive, and our product candidates may become obsolete.
- If we are unable to establish sales, marketing and distribution capabilities on our own or through collaborations with partners, we may not be successful in commercializing any approved drugs.
- Even if any of our current or future product candidates receive marketing approval, such product candidates may fail to achieve market acceptance by physicians, patients, third-party payors or others in the medical community necessary for commercial success, in which case we may not generate significant revenues or become profitable.
- Even if we are able to commercialize any product candidate, the third-party payor coverage and reimbursement status of newly approved products is uncertain. Failure to obtain or maintain adequate coverage and reimbursement for our product candidates could limit our ability to market those products and decrease our ability to generate revenue.
- Our future growth may depend, in part, on our ability to commercialize products in foreign markets, where we would be subject to additional regulatory burdens and other risks and uncertainties.
- EU drug marketing and reimbursement regulations may materially affect our ability to market and receive coverage for our products in the EU Member States.
- Obtaining and maintaining marketing approval of our product candidates in one jurisdiction does not mean that we will be successful in obtaining marketing approval of our product candidates in other jurisdictions.
- If the market opportunities for any of our product candidates are smaller than we estimate, even assuming approval of a product candidate, our revenue may be adversely affected, and our business may suffer.
- If we or our partners market products in a manner that violates fraud and abuse and other healthcare laws, or if we or they violate government price reporting laws, we or our partners may be subject to administrative civil and/or criminal penalties.
- Risks Related to Intellectual Property
- Our success depends in part on our ability to protect our intellectual property and proprietary technologies.
- With respect to certain patents, we enjoy only limited geographical protection, and as a consequence we may not be able to protect our intellectual property rights throughout the world.
- Our intellectual property rights may not adequately protect our technologies and product candidates and may not necessarily address all potential threats to our competitive advantage.
- Others may claim an ownership interest in our intellectual property, which could expose us to litigation and have a significant adverse effect on our prospects.
- We may be subject to claims by third parties asserting that we or our employees have misappropriated third-party intellectual property or claiming ownership of what we regard as our own intellectual property. These claims may be costly to defend and if we do not successfully do so, we may be required to pay monetary damages and lose valuable intellectual property rights or personnel.
- Risks Related to Our Reliance on Third Parties
- We rely on third parties to conduct, supervise and monitor our preclinical studies and clinical trials, and if those third parties perform in an unsatisfactory manner it may harm our business.
- We seek to partner with third-party collaborators with respect to aspects of the development and commercialization of our product candidates and we may not succeed in establishing and maintaining collaborative relationships, which may significantly limit our ability to develop and commercialize our product candidates successfully, if at all.
- If the third parties on which we intend to rely for our clinical trials and results do not perform our clinical trial activities in accordance with good clinical practices and related regulatory requirements, we may be unable to obtain marketing authorization for or commercialize our product candidates.
- Use of third parties to manufacture our product candidates may increase the risk that we will not have sufficient quantities of our product candidates, products, or necessary quantities at an acceptable cost.
- Risks Related to our Business Operations
- We only have a limited number of employees to manage and operate our business. Our business could suffer if we are unable to attract and retain key employees.
- If we or any third-party manufacturers we engage fail to comply with environmental, health and safety laws and regulations, we could become subject to fines or penalties or incur costs or liabilities that could harm our business.
- Any pandemic, epidemic, or outbreak of an infectious disease, may materially and adversely affect our business and our financial results and could cause a disruption to the development of our product candidates.
- We are currently operating in a period of economic uncertainty and capital markets disruption, which has been significantly impacted by geopolitical instability. Our business, financial condition and results of operations could be materially adversely affected by any negative impact on the global economy and capital markets resulting from the geopolitical tensions or high inflation.
- Disruptions at the FDA, the SEC and other government agencies caused by the change in presidential administration, funding shortages or potential funding shortages could hinder their ability to hire and retain key leadership and other personnel, prevent new products and services from being developed or commercialized in a timely manner, or otherwise prevent those agencies from performing normal business functions, which could negatively impact our business and our timelines.
- Our business and operations could suffer in the event of computer system failures or security breaches.
- Risks Related to our Ordinary Shares and ADSs
- Our business, operating results and growth rates may be adversely affected by current or future unfavorable economic and market conditions and adverse developments with respect to financial institutions and associated liquidity risk.
- If we are deemed or become a passive foreign investment company for U.S. federal income tax purposes in 2025 or in any prior or subsequent years, there may be negative tax consequences for U.S. taxpayers that are holders of our ADSs.
- The market price of our ADSs may be volatile and may fluctuate in a way that is disproportionate to our operating performance.
- Insiders own a significant amount of our outstanding shares which could delay or prevent a change in corporate control or result in the entrenchment of management and/or the board of directors.
- Future sales and issuances of our Ordinary Shares or ADSs or rights to purchase ordinary shares or ADSs pursuant to our equity incentive plans could result in additional dilution of the percentage ownership of our shareholders and could cause our share price to fall.
- Provisions in our Articles of Association and under English law could make an acquisition of our Company more difficult and may prevent attempts by our shareholders to replace or remove our organization management.
- We have in the past and may in the future fail to meet the requirements for continued listing on Nasdaq. If we fail to maintain compliance with the minimum listing requirements, our ADSs may be delisted, which could have a material adverse effect on the liquidity of our ADSs.
- We do not anticipate paying cash dividends, and accordingly, shareholders must rely on appreciation in our ADSs for any return on their investment.
- We incur significant costs and demands upon management as a result of complying with the laws and regulations affecting public companies, which could harm our operating results.
- U.S. investors may not be able to enforce their civil liabilities against our Company or certain of our directors, controlling persons and officers.
- The rights of our shareholders may differ from the rights typically offered to shareholders of a U.S. corporation.
- Provisions in the UK City Code on Takeovers and Mergers may have anti-takeover effects that could discourage an acquisition of us by others, even if an acquisition would be beneficial to our shareholders.
- Holders of ADSs must act through the depositary to exercise their rights as shareholders of our Company.
- Holders of our ADSs may be subject to limitations on transfers of ADSs.
Legal proceedings
From time to time, we may become involved in litigation relating to claims arising out of operations in the normal course of business, which we consider routine and incidental to our business.
Refer to Note 10 of the Notes to our consolidated financial statements included elsewhere in this Form 10-K (such consolidated financial statements, the “consolidated financial statements”) related to commitments and contingencies, which is incorporated herein by reference.
The opening of Item 3, Legal Proceedings.6
Sources
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- 19SEC EDGARAbizer Gaslightwala, President
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- 25SEC EDGARPablo Jimenez, Chief Medical Officer
- 26SEC EDGARDonald A. Williams, Board member
- 27SEC EDGARMichael Grissinger, Board member
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- 29SEC EDGARRobert B. Bazemore, Board member
- 30SEC EDGARHoyoung Huh, Board member
- 31SEC EDGARJames R. Neal, Board member
- 32SEC EDGARSandip I. Patel, Board member
- 33SEC EDGARAbizer Gaslightwala, Board member
- 34SEC EDGARAllan Shaw, Board member
- 35SEC EDGARAimos Eiran, Board member
- 36SEC EDGARDavid Sidransky, Board member
- 37SEC EDGARJohnson Yiu Nam Lau, Board member
- 38SEC EDGARRobert F. Doman, Board member
- 39SEC EDGARRay Prudo, Board member
- 40SEC EDGARStuart Ungar, Board member
- 41SEC EDGARRobert M. Shaw, General counsel
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- 45SEC EDGARExecutive or director change
- 46SEC EDGARResults of operations
- 47SEC EDGARShareholder vote
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- 54SEC EDGARRegulation FD disclosure
- 55SEC EDGARListing notice or transfer
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