Cadence Bank

Between 1987 and 1998, the bank acquired First Mississippi National Bank, Volunteer Bank of Jackson, Tennessee, and Alabama Bancorp.

In April 2000, the bank acquired First United Bancshares of El Dorado, Arkansas. First United Bancshares was acquired for $455 million in a tax-free exchange of stock where BancorpSouth gave 1.125 shares of its common stock for each share of First United Bancshares stock.

In 2002, the bank acquired Pinnacle Bancshares. In 2004, the bank acquired Business Bank of Baton Rouge, Louisiana, and Premier Bank of Brentwood, Tennessee.

In 2005, the bank acquired American State Bank of Jonesboro, Arkansas. In October 2006, the bank acquired City Bancorp of Springfield, Missouri, for $170 million with half consisting of BancorpSouth stock and the remainder in cash.

In January 2014, the bank acquired Ouachita Bancshares Corp. of Monroe, Louisiana, and Central Community Corporation of Temple, Texas. Ouachita Bancshares Corp. was purchased for 3,675,000 shares of BancorpSouth's common stock plus $22.875 million in cash. Central Community Corporation was purchased for 7,250,000 shares of BancorpSouth's common stock plus $28.5 million in cash. After nearly four years and multiple extension of completion dates, the bank received the necessary approvals in late 2017 to close the transactions. Both mergers were completed effective January 15, 2018.

In July 2017, the bank reorganized to eliminate redundant corporate infrastructure and activities. BancorpSouth, Inc. was merged with and into its wholly owned bank subsidiary, BancorpSouth Bank. The reorganization left BancorpSouth Bank as the surviving entity. This left BancorpSouth Bank being regulated by the Federal Deposit Insurance Corporation and the Mississippi Department of Banking and Consumer Finance. Before the reorganization, BancorpSouth, Inc. was regulated by the Federal Reserve as a bank holding company.

In April 2018, the bank acquired Icon Capital Corporation and its wholly owned subsidiary Icon Bank of Texas, National Association of Houston, Texas, for 4,125,000 shares of BancorpSouth's common stock plus $17.5 million in cash. The merger was completed on October 1, 2018, and folds in seven open full-service banking offices as well as two not-yet-opened full-service banking offices into BancorpSouth's footprint.

In November 2018, the bank acquired Casey Bancorp, Inc. of Grand Prairie, Texas, and its wholly owned subsidiary, Grand Bank of Texas. Also, the bank acquired Merchants Trust, Inc. of Jackson, Alabama, and its wholly owned subsidiary, Merchants Bank. Casey Bancorp, Inc. was purchased for 1,275,000 shares of BancorpSouth's common stock plus $11.000 million in cash with the agreement providing a collar with respect to the total deal value ranging from $51.750 million to $56.750 million. Merchants Trust, Inc. was purchased for 950,000 shares of BancorpSouth's common stock plus $8.000 million in cash with the agreement providing a collar with respect to the total deal value ranging from $37.500 million to $43.000 million. Both mergers were completed effective April 1, 2019.

Cadence offered checking and savings accounts, loans, credit cards, wealth management, insurance, and financial advice. It also offered conforming, FHA, Jumbo, VA, and USDA mortgages as well as HELOCs. For businesses, it offered small business banking and treasury management services.

In April 1999, the bank acquired Stewart, Sneed, Hewes Group of Gulfport, Mississippi.

In April 2003, the bank acquired WMS, LLC of Baton Rouge, Louisiana, which operated under the name of Wright & Percy Insurance. Also, in July of the same year, the bank acquired Ramsey, Krug, Farrell and Lensing, Inc. of Little Rock, Arkansas.

In February 2008, the bank acquired JMG/IC Insurance Agency, Inc. of Nacogdoches, Texas.

In June 2012, the bank acquired The Securance Group, Inc. of Brewton, Alabama.