MAIA on NYSE
MAIA Biotechnology, Inc.
MAIA Biotechnology, Inc. is an American pharmaceutical preparations company based in Chicago.1
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Last updated Oct 21, 2026.
Overview
- TickerMAIA on NYSE1
- IndustryPharmaceutical Preparations1
- HeadquartersChicago, Illinois1
- Incorporated inDE2
- Business address444 West Lake Street, Suite 1700, Chicago, Il 606062
- Filer category, Emerging growth company2
- Legal formCorporation
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The patients received either 60mg, 180mg, or 360mg of ateganosine per dose, and 42 had at least one post baseline assessment completed.3 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Key numbers, fiscal 2024
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.4
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Research and development expenses | $14.5M | $10.0M |
| General and administrative expenses | $9.7M | $6.9M |
| Total operating expenses | $24.3M | $17.0M |
| Loss from operations | -$24.3M | -$17.0M |
| Interest expense | -$57 | |
| Interest income | $314.0K | $318.4K |
| Australian research and development incentives | $80.0K | |
| Grant income | $361.4K | |
| Change in fair value of warrant liability | $1.2M | -$6.7M |
| Loss on fair value of warrants over proceeds | -$13.0K | |
| Other income (expense) net: | $1.9M | -$6.3M |
| Net loss | -$22.4M | -$23.3M |
| Net loss per share - basic | -$0.70 | -$1.05 |
| Net loss per share - diluted | -$0.70 | -$1.05 |
| Weighted average common shares outstanding - basic | 32.1M shares | 22.2M shares |
| Weighted average common shares outstanding - diluted | 32.1M shares | 22.2M shares |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 3 fiscal years (annual) or 3 quarters (quarterly), latest first.4
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Cash | $8.7M | $9.6M | |
| Prepaid expenses and other current assets | $1.0M | $473.8K | |
| Australia research and development incentives receivable | $77.3K | ||
| Total current assets | $9.7M | $10.2M | |
| Other assets | $2.8K | $2.8K | |
| Total assets | $9.7M | $10.2M | |
| Accounts payable | $2.0M | $1.5M | |
| Accrued expenses | $3.8M | $2.3M | |
| Total current liabilities | $5.8M | $3.8M | |
| Warrant liability | $1.5M | $2.7M | |
| Total liabilities | $7.3M | $6.5M | |
| Common stock, $0.0001 par value, 150,000,000 and 70,000,000 shares authorized at December 31, 2025 and December 31, 2024, 38,624,289 and 26,157,788 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | $3.9K | $2.6K | |
| Additional paid-in capital | $112.1M | $90.9M | |
| Accumulated deficit | -$109.6M | -$87.2M | |
| Accumulated other comprehensive loss | -$50.2K | -$30.6K | |
| Total stockholders equity | $2.4M | $3.6M | $477.5K |
| Total liabilities and stockholders equity | $9.7M | $10.2M | |
| Preferred stock, par value | $0.00 | $0.00 | |
| Preferred stock, shares authorized | 30.0M shares | 30.0M shares | |
| Preferred stock, shares issued | 0 shares | 0 shares | |
| Preferred stock, shares outstanding | 0 shares | 0 shares | |
| Common stock, par value | $0.00 | $0.00 | |
| Common stock, shares authorized | 150.0M shares | 70.0M shares | |
| Common stock, shares issued | 38.6M shares | 26.2M shares | |
| Common stock, shares outstanding | 38.6M shares | 26.2M shares |
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Cash | $8.7M | $9.6M | |
| Prepaid expenses and other current assets | $1.0M | $473.8K | |
| Australia research and development incentives receivable | $77.3K | ||
| Total current assets | $9.7M | $10.2M | |
| Other assets | $2.8K | $2.8K | |
| Total assets | $9.7M | $10.2M | |
| Accounts payable | $2.0M | $1.5M | |
| Accrued expenses | $3.8M | $2.3M | |
| Total current liabilities | $5.8M | $3.8M | |
| Warrant liability | $1.5M | $2.7M | |
| Total liabilities | $7.3M | $6.5M | |
| Common stock, $0.0001 par value, 150,000,000 and 70,000,000 shares authorized at December 31, 2025 and December 31, 2024, 38,624,289 and 26,157,788 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | $3.9K | $2.6K | |
| Additional paid-in capital | $112.1M | $90.9M | |
| Accumulated deficit | -$109.6M | -$87.2M | |
| Accumulated other comprehensive loss | -$50.2K | -$30.6K | |
| Total stockholders equity | $2.4M | $3.6M | $477.5K |
| Total liabilities and stockholders equity | $9.7M | $10.2M | |
| Preferred stock, par value | $0.00 | $0.00 | |
| Preferred stock, shares authorized | 30.0M shares | 30.0M shares | |
| Preferred stock, shares issued | 0 shares | 0 shares | |
| Preferred stock, shares outstanding | 0 shares | 0 shares | |
| Common stock, par value | $0.00 | $0.00 | |
| Common stock, shares authorized | 150.0M shares | 70.0M shares | |
| Common stock, shares issued | 38.6M shares | 26.2M shares | |
| Common stock, shares outstanding | 38.6M shares | 26.2M shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.4
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$22.4M | -$23.3M |
| Stock-based compensation | $2.6M | $1.9M |
| Restricted shares issued for consulting and research expense | $618.8K | $179.5K |
| Change in fair value of warrant liability | -$1.2M | $6.7M |
| Loss on fair value of warrants over proceeds | $13.0K | |
| Prepaid expenses and other current assets | -$579.8K | -$195.9K |
| Australia research and development incentives receivable | $80.4K | $56.8K |
| Accounts payable | $519.7K | -$118.8K |
| Accrued expenses | $1.5M | -$979.8K |
| Net cash used in operating activities | -$18.8M | -$15.7M |
| Proceeds from exercise of stock options | $844 | $217.2K |
| Proceeds from exercise of warrants | $901.6K | |
| Proceeds from At-The-Market offering | $7.2M | $10.1M |
| Payment of offering transactions costs | -$617.1K | -$795.3K |
| Net cash provided by financing activities | $17.9M | $18.2M |
| Net effect of foreign currency exchange on cash | -$5.2K | -$21.5K |
| Net (decrease) increase in cash | -$943.3K | $2.5M |
| Warrants issued in connection with private placement offering 1 2024 | $2.0M | |
| Warrants issued in connection with private placement offering 2 2024 | $1.2M | |
| Warrants issued in connection with private placement offering 3 2024 | $677.9K | |
| Warrants issued in connection with private placement offering 4 2024 | $1.8M | |
| Warrants issued in connection with private placement offering 5 2024 | $635.3K | |
| Warrants issued in connection with private placement offering 1 2025 | $1.1M | |
| Warrants issued in connection with private placement offering 2 2025 | $571.6K | |
| Warrants issued in connection with private placement offering 3 2025 | $462.6K | |
| Warrants issued in connection with private placement offering 4 2025 | $300.2K | |
| Warrants issued in connection with private placement offering 5 2025 | $865.3K | |
| Warrants issued in connection with private placement offering 6 2025 | $251.5K | |
| Warrants issued in connection with private placement offering 7 2025 | $546.7K |
No quarter-by-quarter statement was filed.
Corporate structure
MAIA Biotechnology, Inc. sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.
Major holders of MAIA Biotechnology, Inc.
- Solas Capital Management, LLC Filed SCHEDULE 13G/A on MAIA Biotechnology, Inc., latest Aug 14, 2026 (2 filings since May 15, 2026)
- Vlad Vitoc Filed SCHEDULE 13D/A on MAIA Biotechnology, Inc., latest Dec 4, 2025 (3 filings since Feb 14, 2023)
- FGMK Business Holdings, LLC Filed SCHEDULE 13G on MAIA Biotechnology, Inc., latest Mar 3, 2025
- Sergei Gryaznov Filed SCHEDULE 13G/A on MAIA Biotechnology, Inc., latest Feb 14, 2025 (2 filings since Feb 14, 2023)
- Ngar Yee Louie Filed SC 13D on MAIA Biotechnology, Inc., latest Oct 25, 2024 (2 filings since Feb 14, 2023)
- Stan Smith Filed SC 13D/A on MAIA Biotechnology, Inc., latest Oct 25, 2024 (2 filings since Aug 10, 2022)
- MAIA Biotechnology, Inc. Chicago, Illinois
Built from major holders from Schedules 13D and 13G. Each entity in the chart links to its source.
What it owns
What MAIA Biotechnology, Inc. reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.
Investments
Properties, in its own words
Our headquarters is in Chicago, Illinois where we currently lease office space with approximately 124 square feet under a twelve month lease starting in April 2025, under which we currently pay $3,325 per month. We believe that this space is sufficient to meet our needs for the foreseeable future and that any additional space we may require will be available on commercially reasonable terms. Additionally, we intend to maintain our business model designed to leverage virtual technology to minimize brick and mortar facilities while optimizing our ability to attract top talented employees that may reside in any geography.
Item 2 of the 10-K filed Mar 23, 2026.3
Leadership
Who has led MAIA Biotechnology, Inc., and when. Pick a name to see everywhere that person has worked.
- Chief executive officerVlad Vitoc Jul 27, 2022 to now10
- Chief financial officerJoseph F. McGuire Jul 27, 2022 to Jun 5, 202311
Board members and other officers (11)
- Head of FinanceJeffrey C. Himmelreich Nov 20, 2023 to now12
- Chief Medical OfficerMihail Obrocea Jul 27, 2022 to Jun 5, 202313
- Chief Scientific OfficerSergei Gryaznov Jul 27, 2022 to now14
- Board memberJean-Manasse Theagene Mar 23, 2023 to now15
- Board memberCristian Luput Jul 27, 2022 to now16
- Board memberLaurentiu Vlad Jul 27, 2022 to Jan 4, 202317
- Board memberNgar Yee Louie Jul 27, 2022 to now18
- Board memberRamiro Guerrero Jul 27, 2022 to now19
- Board memberStan Smith Jul 27, 2022 to now20
- Board memberSteven M. Chaouki Jul 27, 2022 to now21
- Board memberVlad Vitoc Jul 27, 2022 to now10
Named in SEC Form D filings
People the company listed in its private-offering notices.
- DirectorLouie Ngar Yee named Nov 12, 2024 to Jan 5, 202622
Timeline
- Oct 6, 20268-K Regulation FD disclosure23
- May 22, 20268-K Shareholder vote24
- May 14, 20268-K Ended a material agreement25
- Apr 16, 20268-K Other events26
- Apr 8, 20268-K Other events27
- Apr 2, 20268-K Executive or director change28
- Mar 31, 20268-K Other events29
- Mar 27, 20268-K Regulation FD disclosure; Other events30
- Mar 4, 20268-K Entered a material agreement; Other events31
- Feb 24, 20268-K Other events32
- Jan 20, 20268-K Other events33
- Jan 13, 20268-K Regulation FD disclosure; Other events34
- Jul 27, 2022New chief executive Vlad Vitoc becomes CEO10
Calendar
Coming up
- Nov 6, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported ($0.27) a share, on Nov 7, 2025.35
When it reported results
- Nov 7, 2023Reported quarterly or annual results36
- Aug 8, 2023Reported quarterly or annual results37
- May 8, 2023Reported quarterly or annual results38
- Mar 24, 2023Reported quarterly or annual results39
- Nov 9, 2022Reported quarterly or annual results40
- Aug 22, 2022Reported quarterly or annual results41
Drug trials and FDA: coming up
- Jul 31, 2027Phase 3 trial readout expected Phase 3 trial of 6-Thio-2'-Deoxyguanosine, Cemiplimab and others in Carcinoma, Non-Small -Cell Lung: primary completion expected Jul 31, 2027 (ClinicalTrials.gov NCT06908304).42
- Sep 30, 2027Phase 2 trial readout expected Phase 2 trial of 6-Thio-2'-Deoxyguanosine and Cemiplimab in Carcinoma, Non-Small-Cell Lung: primary completion expected Sep 30, 2027 (ClinicalTrials.gov NCT05208944).43
Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). Trials from ClinicalTrials.gov, as the sponsor registered them (expected dates are the sponsor's own and often move); approvals and advisory committee meetings from the FDA. The FDA does not publish its decision (PDUFA) dates. The full markets calendar
Filings
503 filings to the SEC since October 2021: 4 annual reports, 14 quarterly reports, 110 major events, 248 insider forms, 12 large holders, 7 private raises, 108 other. The latest 20:
- Oct 7, 2026424B3 EDGAR
- Oct 6, 2026EFFECT EDGAR
- Oct 6, 20268-K EDGAR
- Oct 2, 20264 PRIMARY DOCUMENT EDGAR
- Oct 2, 20264 PRIMARY DOCUMENT EDGAR
- Oct 2, 20264 PRIMARY DOCUMENT EDGAR
- Oct 2, 20264 PRIMARY DOCUMENT EDGAR
- Oct 2, 20264 PRIMARY DOCUMENT EDGAR
- Oct 2, 20264 PRIMARY DOCUMENT EDGAR
- Oct 2, 2026424B3 EDGAR
- Sep 25, 2026S-3 EDGAR
- Sep 15, 20264 PRIMARY DOCUMENT EDGAR
- Sep 14, 20264 PRIMARY DOCUMENT EDGAR
- Sep 1, 20264 PRIMARY DOCUMENT EDGAR
- Aug 28, 2026EFFECT EDGAR
- Aug 26, 20264 PRIMARY DOCUMENT EDGAR
- Aug 24, 20264 PRIMARY DOCUMENT EDGAR
- Aug 21, 2026S-3 EDGAR
- Aug 14, 2026SCHEDULE 13G/A EDGAR
- Aug 10, 202610-Q EDGAR
The 503 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
145 open-market trades by officers, directors and large owners since October 2021: 145 buys and 0 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Sep 14, 2026 | Vitoc VladChief Executive Officer | Buy | 73,000 | $1.37 | $100.0K | Form 4 |
| Sep 10, 2026 | Guerrero RamiroDirector | Buy | 37,595 | $1.32 | $49.6K | Form 4 |
| Aug 28, 2026 | Guerrero RamiroDirector | Buy | 46,620 | $1.35 | $62.9K | Form 4 |
| Aug 27, 2026 | Guerrero RamiroDirector | Buy | 78,239 | $1.39 | $108.8K | Form 4 |
| Aug 26, 2026 | Guerrero RamiroDirector | Buy | 8,931 | $1.39 | $12.4K | Form 4 |
| Aug 24, 2026 | Guerrero RamiroDirector | Buy | 1,794 | $1.33 | $2.4K | Form 4 |
| Aug 20, 2026 | Guerrero RamiroDirector | Buy | 11,899 | $1.37 | $16.3K | Form 4 |
| Jun 1, 2026 | Vitoc VladChief Executive Officer | Buy | 72,700 | $1.39 | $101.1K | Form 4 |
| Jun 1, 2026 | Smith StanDirector | Buy | 75,000 | $1.34 | $100.5K | Form 4 |
| Jun 1, 2026 | Gryaznov SergeiChief Scientific Officer | Buy | 2,000 | $1.35 | $2.7K | Form 4 |
| Dec 22, 2025 | Smith StanDirector | Buy | 57,189 | $1.22 | $69.8K | Form 4 |
| Dec 22, 2025 | CHAOUKI STEVEN MDirector | Buy | 40,849 | $1.22 | $49.8K | Form 4 |
| Dec 22, 2025 | Louie Ngar YeeDirector | Buy | 81,699 | $1.22 | $99.7K | Form 4 |
| Dec 5, 2025 | Smith StanDirector | Buy | 13,740 | $1.20 | $16.4K | Form 4 |
| Nov 28, 2025 | Vitoc VladChief Executive Officer | Buy | 50,000 | $1.14 | $57.0K | Form 4 |
| Nov 28, 2025 | Vitoc VladChief Executive Officer | Buy | 50,000 | $1.14 | $57.0K | Form 4 |
| Nov 28, 2025 | Luput CristianDirector | Buy | 18,145 | $1.11 | $20.1K | Form 4 |
| Nov 26, 2025 | Vitoc VladChief Executive Officer | Buy | 22,000 | $1.05 | $23.1K | Form 4 |
| Nov 26, 2025 | Vitoc VladChief Executive Officer | Buy | 22,000 | $1.05 | $23.1K | Form 4 |
| Nov 26, 2025 | Luput CristianDirector | Buy | 20,000 | $1.08 | $21.6K | Form 4 |
All 145 trades can be filtered by person here when JavaScript is on.
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- Solas Capital Management, LLCSCHEDULE 13G/A, 2 filings May 15, 2026 to Aug 14, 202644
- Vlad VitocSCHEDULE 13D/A, 3 filings Feb 14, 2023 to Dec 4, 202545
- FGMK Business Holdings, LLCSCHEDULE 13G, 1 filing Mar 3, 202546
- Sergei GryaznovSCHEDULE 13G/A, 2 filings Feb 14, 2023 to Feb 14, 202547
- Ngar Yee LouieSC 13D, 2 filings Feb 14, 2023 to Oct 25, 202448
- Stan SmithSC 13D/A, 2 filings Aug 10, 2022 to Oct 25, 202449
Executive pay
What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.
| Year | Executive | Age | Salary | Total pay |
|---|---|---|---|---|
| 2025 | Vlad Vitoc, M.D. M.B.A.Chief Executive Officer and President | 56 | $612.3K | $2.1M50 |
| 2025 | Sergei GryaznovChief Scientific Officer | 66 | $478.5K | $1.3M50 |
| 2025 | Jeffrey C. HimmelreichHead of Finance | 51 | $272.9K | $421.0K50 |
| 2024 | Vlad Vitoc, M.D. M.B.A.Chief Executive Officer and President | 56 | $473.0K | $1.4M50 |
| 2024 | Sergei GryaznovChief Scientific Officer | 66 | $363.0K | $929.8K50 |
| 2024 | Jeffrey C. HimmelreichHead of Finance | 51 | $240.0K | $338.4K50 |
Funding
Where the company's money came from, by calendar year: private offerings filed with the SEC, federal grants, loans, contracts and other assistance from USAspending.gov, and PPP loans from the SBA. Each bar links to the records below.
- Private raises (Form D) $19.6M
Figures by year
| Year | Private raises (Form D) | Total |
|---|---|---|
| 2025 | $9.3M | $9.3M |
| 2024 | $5.4M | $5.4M |
| 2023 | $4.9M | $4.9M |
Private raises
Private offerings the company reported to the SEC on Form D. The amount is what the latest filing says was sold so far, charted in the year of the first sale. Covers filings since Oct 1, 2021.
- Dec 22, 2025Raised $1.5 million in a private offering of equity22 Form D: $2 million offered in all Form D
- Sep 29, 2025Raised $3 million in a private offering of equity51 Form D: $7 million offered in all Form D
- May 28, 2025Raised $694,998 in a private offering of equity52 Form D: $8 million offered in all Form D
- Feb 18, 2025Raised $4.1 million in a private offering of equity53 Form D: $5.9 million offered in all Form D
- Oct 28, 2024Raised $2.4 million in a private offering of equity54 Form D: $15.5 million offered in all Form D
- Mar 11, 2024Raised $2.9 million in a private offering of equity55 Form D: $5.7 million offered in all Form D
- Nov 15, 2023Raised $4.9 million in a private offering of equity56 Form D: 3 investors so far Form D
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 36. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| Solas Capital Management, LLC | 3,030,845 | $4.4M | 2.3% | −1,266,159 |
| Alyeska Investment Group, L.P. | 2,500,000 | $3.6M | 0.0% | No change |
| Vanguard Capital Management LLC | 2,413,270 | $3.5M | 0.0% | +339,225 |
| 683 Capital Management, LLC | 1,066,666 | $1.5M | 0.1% | No change |
| Centric Wealth Management | 796,723 | $1.1M | 0.2% | No change |
| Cable Car Capital, LP | 514,583 | $741.0K | 0.0% | −133,920 |
| Geode Capital Management, LLC | 504,380 | $726.6K | 0.0% | +143,899 |
| Bleichroeder LP | 500,000 | $720.0K | 0.1% | No change |
| Renaissance Technologies LLC | 415,700 | $598.6K | 0.0% | New |
| BlackRock, Inc. | 403,011 | $580.3K | 0.0% | +275,033 |
| Vanguard Fiduciary Trust Co | 336,688 | $484.8K | 0.0% | +137,374 |
| State Street Corp | 201,750 | $290.5K | 0.0% | +62,800 |
| Bleakley Financial Group, LLC | 181,623 | $261.5K | 0.0% | New |
| Northern Trust Corp | 125,171 | $180.2K | 0.0% | +72,632 |
| Morgan Stanley | 104,017 | $149.8K | 0.0% | +90,158 |
| Bridgeway Capital Management, LLC | 76,000 | $109.4K | 0.0% | +40,000 |
| Two Sigma Investments, LP | 50,383 | $72.6K | 0.0% | New |
| Envestnet Asset Management Inc | 44,347 | $63.9K | 0.0% | New |
| Susquehanna International Group, Llp | 35,223 | $50.7K | 0.0% | New |
| Pvg Asset Management Corp | 34,135 | $49.2K | 0.0% | No change |
| UBS Group AG | 33,435 | $48.1K | 0.0% | −18,482 |
| Citadel Advisors LLC | 24,890 | $35.8K | 0.0% | New |
| Cetera Investment Advisers | 22,748 | $32.8K | 0.0% | New |
| Lazari Capital Management, Inc. | 21,750 | $31.3K | 0.0% | New |
| Atria Investments, Inc | 21,100 | $30.4K | 0.0% | New |
13F reports cover disclosed long positions in U.S. stocks only.
SEC filer profile
How MAIA Biotechnology, Inc. is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.
- Name on EDGARMAIA Biotechnology, Inc.1
- CIK0001878313
- Employer ID (EIN)83-14959133
- Filer statusNon-accelerated filer an emerging growth company; a smaller reporting company; a shell company3
- Incorporated inDelaware3
- Fiscal year endsDecember 311
- Industry code (SIC)2834 Pharmaceutical Preparations1
- SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
- Business address444 West Lake Street, Suite 1700, Chicago, IL 606061
- Phone312-416-85921
- Shares outstanding60,825,844 as of Aug 10, 20269
- Public float$48.9M as of Jun 30, 20253
- AuditorGRANT THORNTON LLP, Charlotte, North Carolina PCAOB ID 248; no auditor attestation of internal control over financial reporting3
- On EDGAR sinceOct 15, 20211
- Filings503 in all: 4 (231), 8-K (109), CORRESP (25), 10-Q (13), 3 (12), 424B5 (11), UPLOAD (11), S-1/A (9)1
All 38 form types
FWP (8), D (7), 4/A (5), EFFECT (5), S-8 (5), 10-K (4), DEF 14A (4), DEFA14A (4), 424B3 (3), DRS (3), S-1 (3), S-3 (3), SC 13D (3), SC 13G (3), 424B4 (2), DRS/A (2), DRSLTR (2), SCHEDULE 13G (2), SCHEDULE 13G/A (2), SEC STAFF LETTER (2), 10-Q/A (1), 144 (1), 8-A12B (1), 8-K/A (1), ARS (1), CERT (1), PRE 14A (1), RW (1), SC 13D/A (1), SCHEDULE 13D/A (1)
- Latest filingsAnnual report (10-K) Mar 23, 2026
Quarterly report (10-Q) Aug 10, 2026
Proxy statement (DEF 14A) Apr 7, 2026
Latest 8-K (8-K) Oct 6, 2026
Securities registered for trading
| Class | Symbol | Exchange |
|---|---|---|
| Common Stock, $0.0001 par value per share | MAIA | NYSE American |
From the cover page of the 10-K filed Mar 23, 2026 (Section 12(b) of the Exchange Act).3
Risk factors and legal proceedings
The risks MAIA Biotechnology, Inc. names in Item 1A of its 10-K filed Mar 23, 2026: 71 risks under these headings, as written.3
- Risks Related to Our Financial Position and Need for Additional Capital
- We have incurred losses since inception and anticipate that we will continue to incur losses for the foreseeable future. We are not currently profitable, and we may never achieve or sustain profitability.
- We will require additional capital to fund our operations, and if we fail to obtain necessary financing, we may not be able to complete the development and commercialization of ateganosine.
- Raising additional capital may cause dilution to our stockholders, restrict our operations or require us to relinquish rights to our technologies or product candidates.
- We have a limited operating history and no history of commercializing pharmaceutical products, which may make it difficult to evaluate the prospects for our future viability.
- Risks Related to Development, Clinical Trials, Manufacturing and Regulatory Approval
- We are heavily dependent on the success of ateganosine, our most advanced candidate, which is still under clinical development, and if this drug does not receive regulatory approval or is not successfully commercialized, our business may be harmed.
- Pandemics, such as COVID-19, may adversely impact our business, results of operations, financial condition, liquidity and cash flows and that of our clients.
- Clinical trials are expensive, time-consuming and difficult to design and implement, and involve an uncertain outcome.
- Our product candidates are based on novel technologies, which make it difficult to predict the timing, results and cost of product candidate development and likelihood of obtaining regulatory approval.
- Serious adverse events, undesirable side effects or other unexpected properties of our product candidates may be identified during development or after approval, which could lead to the discontinuation of our clinical development programs, refusal by regulatory authorities to approve our product candidates or, if discovered following marketing approval, revocation of marketing authorizations or limitations on the use of our product candidates thereby limiting the commercial potential of such product candidate.
- Interim, topline and preliminary data from our clinical trials may change as more patient data become available and are subject to audit and verification procedures that could result in material changes in the final data.
The other 61 risks
- Disruptions at the FDA and other government agencies caused by funding shortages or global health concerns could hinder their ability to hire, retain or deploy key leadership and other personnel, or otherwise prevent new or modified products from being developed, or approved or commercialized in a timely manner or at all, which could negatively impact our business.
- We may expend our limited resources to pursue a particular product candidate or indication and fail to capitalize on product candidates or indications that may be more profitable or for which there is a greater likelihood of success.
- We may not be successful in our efforts to identify or discover additional product candidates in the future.
- The regulatory approval processes of the FDA and comparable foreign authorities are lengthy, time consuming, expensive, and inherently unpredictable, and if we are ultimately unable to obtain regulatory approval for ateganosine or any other candidates, our business will be substantially harmed.
- Enrollment and retention of patients in clinical trials is an expensive and time-consuming process and could be made more difficult or rendered impossible by multiple factors outside our control.
- Results of preclinical studies, early clinical trials or analyses may not be indicative of results obtained in later trials.
- The market opportunities for ateganosine, if approved, may be smaller than we anticipate.
- We have never obtained marketing approval for a development candidate and we may be unable to obtain, or may be delayed in obtaining, marketing approval for any of our development candidates.
- Development of ateganosine could take longer, be more expensive, or become impractical if the FDA requires the use of an FDA-approved companion diagnostic test in conjunction with treatment with ateganosine.
- Even if we obtain FDA approval for ateganosine or any other candidates in the United States, we may never obtain approval for or commercialize ateganosine or any other development candidate in any other jurisdiction, which would limit our ability to realize their full global market potential.
- Even if we obtain regulatory approval for ateganosine or any development candidate, we will still face extensive and ongoing regulatory requirements and obligations and any development candidates, if approved, may face future development and regulatory difficulties.
- We may seek a Breakthrough Therapy designation for ateganosine from the FDA. However, we might not seek such designation or be granted the designation by the FDA if sought, and even if we are granted the designation, it may not lead to a faster development or regulatory review or approval process.
- Risks Related to Commercialization
- We face significant competition from other biotechnology and pharmaceutical companies and our operating results will suffer if we fail to compete effectively.
- We may face early generic competition for ateganosine or our other products.
- The successful commercialization of ateganosine and any other candidate we develop will depend in part on the extent to which governmental authorities and health insurers establish adequate coverage, reimbursement levels, and pricing policies. Failure to obtain or maintain coverage and adequate reimbursement for our candidates, if approved, could limit our ability to market those products and decrease our ability to generate revenue.
- Even if ateganosine or any candidate we develop receives marketing approval, it may fail to achieve market acceptance by physicians, patients, third-party payors or others in the medical community necessary for commercial success.
- If we are unable to establish sales, marketing and distribution capabilities either on our own or in collaboration with third parties, we may not be successful in commercializing ateganosine, if approved.
- A variety of risks associated with operating internationally could materially adversely affect our business.
- Risks Related to Our Dependence on Third Parties
- Our employees and independent contractors, including principal investigators, clinical trial sites, contract research organizations (“CROs”), consultants, vendors, and any third parties we may engage in connection with development and commercialization, may engage in misconduct or other improper activities, including noncompliance with regulatory standards and requirements, which could have a material adverse effect on our business.
- We currently rely on third-party contract manufacturing organizations, or CMOs, for the production of clinical supply of ateganosine and intend to rely on CMOs for the production of commercial supply of ateganosine, if approved. Our dependence on CMOs may impair the development and commercialization of the drug, which would adversely impact our business and financial position.
- We intend to continue to rely on third parties to conduct, supervise and monitor our clinical trials. If those third parties do not successfully carry out their contractual duties, or if they perform in an unsatisfactory manner, it may harm our business.
- The number and type of our collaborations could adversely affect our attractiveness to future collaborators or acquirers and the loss of, or a disruption in our relationship with, any one or more collaborators could harm our business.
- Risks Related to Healthcare Laws and Other Legal Compliance Matters
- Enacted and future healthcare legislation may increase the difficulty and cost for us to obtain marketing approval of and commercialize our development candidates, if approved, and may affect the prices we may set.
- Our business operations and current and future relationships with investigators, healthcare professionals, consultants, third-party payors, patient organizations, and customers will be subject to applicable healthcare regulatory laws, which could expose us to penalties.
- Any clinical trial programs we conduct or research collaborations we enter into in the European Economic Area may subject us to the General Data Protection Regulation.
- We are subject to environmental, health and safety laws and regulations, and we may become exposed to liability and substantial expenses in connection with environmental compliance or remediation activities.
- Recent legislation may materially adversely affect our financial condition, results of operations and cash flows.
- Risks Related to Our Intellectual Property
- We depend on license agreements with the University of Texas Southwestern, or UTSW, to permit us to use patents and patent applications, as well as to exploit specific technological know-how. Termination of these rights or the failure to comply with obligations under these agreements could materially harm our business and prevent us from developing or commercializing our product candidates.
- We have been granted licenses of use to patent applications. There can be no assurance that any of the patent applications that we have licenses to will result in issued patents. As a result, our ability to protect our proprietary technology in the marketplace may be limited.
- Our proprietary position for our product candidates currently depends in part upon licenses to patents protecting methods of use, which may not prevent a competitor or other third party from using the same product candidate for another use.
- Our patents may be challenged in courts or in patent offices which could result in the invalidation, narrowing or unenforceability of our patents and our patent portfolio may not provide us with sufficient rights to exclude others from commercializing products similar or identical to ours.
- We may become subject to third parties’ claims alleging infringement of their patents and proprietary rights, or we may need to become involved in lawsuits to protect or enforce our patents, which could be costly and/or time consuming, delay or prevent the development and commercialization of our product candidates or put our patents and other proprietary rights at risk.
- We may not identify relevant third-party patents or may incorrectly interpret the relevance, scope or expiration of a third-party patent, which might adversely affect our ability to develop, manufacture and market our product candidates.
- Changes in patent laws or patent jurisprudence could diminish the value of patents in general, thereby impairing our ability to protect our product candidates.
- Obtaining and maintaining our patent protection depends on compliance with various procedural, document submission, fee payment and other requirements imposed by governmental patent agencies, and our patent protection could be reduced or eliminated for non-compliance with these requirements.
- We enjoy only limited geographical protection with respect to certain patents and we may not be able to protect our intellectual property rights throughout the world.
- If we do not obtain patent term extension in the United States under the Hatch-Waxman Act and in foreign countries having similar legislation, thereby potentially extending the term of marketing exclusivity for our product candidates, our business may be materially harmed.
- Intellectual property discovered through government funded programs may be subject to federal regulations such as “march-in” rights, certain reporting requirements and a preference for U.S.-based companies. Compliance with such regulations may limit our exclusive rights and limit our ability to contract with non-U.S. manufacturers.
- Intellectual property rights do not address all potential threats to our competitive advantage.
- Our reliance on third parties requires us to share our trade secrets, which increases the possibility that our trade secrets will be misappropriated or disclosed, and confidentiality agreements with employees and third parties may not adequately prevent disclosure of trade secrets and protect other proprietary information.
- If our trademarks and trade names are not adequately protected, then we may not be able to build name recognition in our markets of interest and our business may be adversely affected.
- We may need to license certain intellectual property from third parties, and such licenses may not be available or may not be available on commercially reasonable terms.
- We may be subject to claims that our employees, consultants or independent contractors have wrongfully used or disclosed confidential information of their former employers or other third parties.
- Our proprietary information may be lost, or we may suffer security breaches.
- Risks Related to Our Employees, Managing Our Growth and Our Operations
- Our future success depends on our ability to retain our key personnel and to attract, retain and motivate qualified personnel.
- We expect to expand our development, regulatory, and sales and marketing capabilities, and as a result, we may encounter difficulties in managing our growth, which could disrupt our operations.
- We may engage in acquisitions that could disrupt our business, cause dilution to our stockholders or reduce our financial resources.
- Our business and operations would suffer in the event of system failures.
- Risks Relating to Investing in Digital Securities
- The launch of central bank digital currencies (“CBDCs”) may adversely impact our business.
- Absent federal regulations, there is a possibility that any digital asset we acquire may be classified as a “security.” Any classification of any digital asset we acquire as a “security” would subject us to additional regulation and could materially impact the operation of our business.
- If we were deemed to be an investment company under the 1940 Act, applicable restrictions likely would make it impractical for us to continue segments of our business as currently contemplated.
- We may be subject to regulatory developments related to crypto assets and crypto asset markets, which could adversely affect our business, financial condition, and results of operations.
- Cryptocurrency assets are less liquid than our existing cash and cash equivalents and may not be able to serve as a source of liquidity for us to the same extent as cash and cash equivalents.
- We are not subject to legal and regulatory obligations that apply to investment companies such as mutual funds and exchange-traded funds, or to obligations applicable to investment advisers.
- If we or our third-party service providers experience a security breach or cyberattack and unauthorized parties obtain access to any of our acquired digital assets, or if our private keys are lost or destroyed, or other similar circumstances or events occur, we may lose some or all of our digital assets and our financial condition and results of operations could be materially adversely affected.
- We have limited history in generating staking revenues from digital assets, which could adversely affect our business, financial condition and operating results.
- Competition from other companies staking and utilizing digital assets in their treasury plans.
- We may fail to develop and execute successful investment or trading strategies.
- We may make, or otherwise be subject to, trade errors.
- Risks Relating to Our Common Stock
- If we are unable to comply with the continued listing requirements of the NYSE American, then our Common Stock would be delisted from the NYSE American, which would limit investors’ ability to effect transactions in our Common Stock and subject us to additional trading restrictions.
- Our shares of common stock are thinly traded, and the price may not reflect our value; there can be no assurance that there will be an active market for our shares now or in the future.
Legal proceedings
At the date of the Annual Report on Form 10-K, we are not party to any material legal proceedings. From time to time, we may be involved in legal proceedings or subject to claims incident to the ordinary course of business. Regardless of the outcome, such proceedings or claims can have an adverse impact on us because of defense and settlement costs, diversion of resources and other factors, and there can be no assurances that favorable outcomes will be obtained.
The opening of Item 3, Legal Proceedings.3
Sources
The numbers on this page point here. Each one links to the record it came from.
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- 10SEC EDGARVlad Vitoc, Chief executive officer
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- 15SEC EDGARJean-Manasse Theagene, Board member
- 16SEC EDGARCristian Luput, Board member
- 17SEC EDGARLaurentiu Vlad, Board member
- 18SEC EDGARNgar Yee Louie, Board member
- 19SEC EDGARRamiro Guerrero, Board member
- 20SEC EDGARStan Smith, Board member
- 21SEC EDGARSteven M. Chaouki, Board member
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- 23SEC EDGARRegulation FD disclosure
- 24SEC EDGARShareholder vote
- 25SEC EDGAREnded a material agreement
- 26SEC EDGAROther events
- 27SEC EDGAROther events
- 28SEC EDGARExecutive or director change
- 29SEC EDGAROther events
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- 32SEC EDGAROther events
- 33SEC EDGAROther events
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- 35NasdaqNasdaq calendar
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