MNOV on Nasdaq

MEDICINOVA INC

MEDICINOVA INC is a registered trademark of MediciNova.1 It is headquartered in La Jolla, California.1 Its shares trade on Nasdaq under the symbol MNOV.1

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Last updated Oct 21, 2026.

Overview

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  • TickerMNOV on Nasdaq1
  • IndustryPharmaceutical Preparations1
  • HeadquartersLa Jolla, California1
  • Incorporated inDE2
  • Business address4275 Executive Square, Suite 300, La Jolla, Ca 920372
  • Filer categoryNon-accelerated filer, Smaller reporting company2

The MediciNova logo is a registered trademark of MediciNova, Inc. All other product and company names are registered trademarks or trademarks of their respective companies.3 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-3242.5%Operating margin4
-2928.8%Net margin4
-28.9%Return on equity4
-$9.8MFree cash flow4

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Research and development100¢$6.7M
  • Income tax0¢$6.0K

Out of $409.7K in revenue.4 The company lost money this year.

Financial statements

Revenue564$409.7K in 2025−90% since 2021
0$2.0M$4.0M$6.0M2021: $4.0M$4.0M20212023: $1.0M$1.0M2023−75%2025: $409.7K$409.7K2025−59%
Operating income785964-$13.3M in 2025−5% since 2019
-$15.0M-$10.0M-$5.0M02019: -$14.0M-$14.0M20192020: -$14.2M-$14.2M2020+1%2021: -$10.2M-$10.2M2021−28%2022: -$14.6M-$14.6M2022+43%2023: -$9.9M-$9.9M2023−32%2024: -$12.7M-$12.7M2024+28%2025: -$13.3M-$13.3M2025+5%
Net income785964-$12.0M in 2025−7% since 2019
-$15.0M-$10.0M-$5.0M02019: -$12.9M-$12.9M20192020: -$13.9M-$13.9M2020+7%2021: -$10.1M-$10.1M2021−27%2022: -$14.1M-$14.1M2022+39%2023: -$8.6M-$8.6M2023−39%2024: -$11.0M-$11.0M2024+29%2025: -$12.0M-$12.0M2025+9%

Every line of the income statement as filed: the last 2 fiscal years, latest first.4

Period ending2025-12-312024-12-31
Revenues$409.7K
Cost of services$378.6K
Research, development and patents$7.2M$7.2M
General and administrative$6.2M$5.5M
Total operating expenses$13.7M$12.7M
Operating loss-$13.3M-$12.7M
Interest income$1.3M$1.7M
Other expense, net-$12.8K-$39.5K
Loss before income taxes-$12.0M-$11.0M
Income tax expense-$6.0K-$5.5K
Net loss-$12.0M-$11.0M
Basic net loss per common share-$0.24-$0.23
Diluted net loss per common share-$0.24-$0.23
Shares used to compute basic net loss per common share49.1M shares49.0M shares
Shares used to compute diluted net loss per common share49.1M shares49.0M shares
Foreign currency translation adjustments$8.0K-$17.1K
Comprehensive loss-$12.0M-$11.1M

Compare MEDICINOVA INC with another company

Corporate structure

MEDICINOVA INC sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.

Major holders of MEDICINOVA INC

  • MEDICINOVA INC La Jolla, California

Built from major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

What it owns

What MEDICINOVA INC reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.

Property and equipment

ItemLatestA year beforeChange
Furniture and fixtures$88.5K4 Dec 31, 2025$85.6K4 Dec 31, 2024+3.4%
Computer equipment and software$342.6K4 Dec 31, 2025$342.6K4 Dec 31, 20240%
Property and equipment, before depreciation$431.1K4 Dec 31, 2025$428.2K4 Dec 31, 2024+0.7%
Accumulated depreciation$422.8K4 Dec 31, 2025$402.7K4 Dec 31, 2024+5.0%
Property and equipment, net$8.3K4 Dec 31, 2025$25.5K4 Dec 31, 2024−67.3%
Operating-lease assets (leased space)$184.2K4 Dec 31, 2025$356.9K4 Dec 31, 2024−48.4%

Investments

ItemLatestA year beforeChange
Cash and cash equivalents$30.8M4 Dec 31, 2025$40.4M4 Dec 31, 2024−23.7%

Intangibles and goodwill

ItemLatestA year beforeChange
Goodwill$9.6M4 Dec 31, 2025$9.6M4 Dec 31, 20240%

Properties, in its own words

In December 2017, we executed a sublease agreement for our San Diego headquarters (Sublease) with Cardinal Health 127 Inc., the sublessor, to which Irvine Company, the master lessor, had provided its consent. The Sublease was for approximately 4,400 square feet and had a term of four years and one month. We have extended this Sublease for an additional 5 years through January 31, 2027.

In June 2005, we leased office space in Tokyo, Japan under a non-cancelable operating lease with an original expiration date of May 2013 and an auto-renewal two-year extension. The lease was renewed in May 2023 and has a term of two years with an auto-renewal, two year extension. In April 2024, we provided notice to terminate the previous lease agreement, effective October 2024, and in May 2024, we entered into a new lease agreement, effective June 2024, for a different office space for the Tokyo location. The new lease has an initial lease term of 12 months ending May 2025 with an option to extend for an additional two months, after which there will be automatic two-month renewals until the lease is terminated.

The rest of Item 2

We have no laboratory, research or manufacturing facilities, and we currently do not plan to purchase or lease any such facilities, as such services are provided to us by third party service providers. We believe that our current facilities are adequate for our needs for the immediate future and that, should it be needed, suitable additional space will be available to accommodate expansion of our operations on commercially reasonable terms.

Item 2 of the 10-K filed Mar 10, 2026.3

Leadership

Who has led MEDICINOVA INC, and when. Pick a name to see everywhere that person has worked.

Board members and other officers (26)

Timeline

  1. Sep 28, 20268-K Entered a material agreement48
  2. Sep 2, 20268-K Ended a material agreement49
  3. Aug 19, 20268-K Executive or director change50
  4. Jun 24, 20268-K Shareholder vote51
  5. Feb 20, 20268-K Results of operations52
  6. Dec 30, 20258-K Entered a material agreement53
  7. Aug 1, 20258-K Entered a material agreement54
  8. Jun 18, 20258-K Shareholder vote55
  9. Mar 11, 20258-K Regulation FD disclosure56
  10. Jun 12, 20248-K Shareholder vote57
  11. Apr 1, 20248-K Executive or director change58
  12. Aug 7, 20238-K Executive or director change59
  13. Jan 6, 2006New chief executive Yuichi Iwaki becomes CEO12

Calendar

Coming up

  1. Nov 11, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported ($0.06) a share, on Nov 12, 2025.60

When it reported results

  1. Feb 20, 2026Reported quarterly or annual results52

Drug trials and FDA: coming up

  1. Dec 31, 2026Phase 2 trial readout expected Phase 2 trial of MN-001 in Diabetes Mellitus, Type 2: primary completion expected Dec 31, 2026 (ClinicalTrials.gov NCT05464784).61
  2. Apr 2027Phase 2/3 trial readout expected Phase 2/3 trial of MN-166 in Amyotrophic Lateral Sclerosis: primary completion expected Apr 2027 (ClinicalTrials.gov NCT04057898).62

Drug trials and FDA: recently

  1. Dec 7, 2020Phase 2 trial completed Phase 2 trial of MN-001 in Idiopathic Pulmonary Fibrosis: primary completion Dec 7, 2020, results posted Jan 23, 2026 (ClinicalTrials.gov NCT02503657).63

Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). Trials from ClinicalTrials.gov, as the sponsor registered them (expected dates are the sponsor's own and often move); approvals and advisory committee meetings from the FDA. The FDA does not publish its decision (PDUFA) dates. The full markets calendar

Filings

113 filings to the SEC since October 2021: 6 annual reports, 15 quarterly reports, 18 major events, 38 insider forms, 2 large holders, 34 other. The latest 20:

  1. Sep 29, 20264 EDGAR
  2. Sep 29, 2026SCHEDULE 13D/A EDGAR
  3. Sep 28, 20268-K EDGAR
  4. Sep 2, 20268-K EDGAR
  5. Aug 19, 20268-K EDGAR
  6. Aug 13, 202610-Q EDGAR
  7. Jun 25, 20264 EDGAR
  8. Jun 25, 20264 EDGAR
  9. Jun 25, 20264 EDGAR
  10. Jun 24, 20268-K EDGAR
  11. May 14, 202610-Q EDGAR
  12. Apr 29, 2026ARS EDGAR
  13. Apr 29, 2026DEFA14A EDGAR
  14. Apr 29, 2026DEF 14A EDGAR
  15. Apr 20, 2026PRER14A EDGAR
  16. Apr 17, 2026PRE 14A EDGAR
  17. Mar 10, 202610-K EDGAR
  18. Feb 20, 20268-K EDGAR
  19. Jan 20, 20264 EDGAR
  20. Jan 20, 20264 EDGAR

The 113 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

5 open-market trades by officers, directors and large owners since October 2021: 0 buys and 5 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Sep 25, 20263D Opportunity Master FundSale640,000$2.70$1.7MForm 4
Nov 28, 2022Nagao HidekiDirectorSale6,754$2.25$15.2KForm 4
Nov 22, 2022Nagao HidekiDirectorSale218$2.13$464Form 4
Nov 21, 2022Nagao HidekiDirectorSale5,365$2.18$11.7KForm 4
Nov 17, 2022Nagao HidekiDirectorSale309$2.18$674Form 4

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Executive pay

What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.

YearExecutiveAgeSalaryTotal pay
2025Yuichi IwakiM.D., Ph.D.$657.4K$1.7M65
2025Kazuko MatsudaM.D., Ph.D., MPH$514.4K$1.3M65
2025David H. CreanPh.D.$120.0K65
2024President and Chief Executive Officer$657.4K$1.4M65
2024Senior Vice PresidentChief Medical Officer$505.4K$1.0M65
2024Chief Business Officer$99.0K65

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 29. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Essex Woodlands Management, Inc.1,105,941$1.5M0.6%No change
BlackRock, Inc.752,091$992.8K0.0%+46,137
Citigroup Inc635,715$839.1K0.0%No change
Vanguard Capital Management LLC609,052$803.9K0.0%−1,987
Geode Capital Management, LLC539,312$712.1K0.0%−4,531
Vanguard Fiduciary Trust Co282,608$373.0K0.0%+1,987
UBS Group AG222,200$293.3K0.0%No change
Renaissance Technologies LLC205,400$271.1K0.0%+15,500
State Street Corp193,698$255.7K0.0%No change
Northern Trust Corp143,665$189.6K0.0%+10,502
Bank of New York Mellon Corp78,277$103.3K0.0%No change
Charles Schwab Investment Management Inc71,506$94.4K0.0%No change
Bridgeway Capital Management, LLC56,031$74.0K0.0%No change
SBI Securities Co., Ltd.51,479$68.0K0.0%+6,603
Dimensional Fund Advisors LP50,552$66.7K0.0%No change
Barclays PLC42,806$56.5K0.0%−120,094
Schonfeld Strategic Advisors LLC36,157$47.7K0.0%−219
Susquehanna International Group, Llp26,752$35.3K0.0%−17,174
Jane Street Group, LLC15,818$20.9K0.0%−71,267
Vanguard Global Advisers, LLC15,599$20.6K0.0%No change
Two Sigma Investments, LP13,526$17.9K0.0%−16,283
Bank Of America Corp /de/13,159$17.4K0.0%−21,200
Focus Partners Advisor Solutions, LLC10,000$13.2K0.0%New
Morgan Stanley2,000$2.6K0.0%No change
Northwestern Mutual Wealth Management Co305$4030.0%No change

13F reports cover disclosed long positions in U.S. stocks only.

SEC filer profile

How MEDICINOVA INC is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.

  • Name on EDGARMEDICINOVA INC1
  • CIK0001226616
  • Employer ID (EIN)33-09279793
  • Filer statusNon-accelerated filer not an emerging growth company; a smaller reporting company; not a shell company3
  • Incorporated inDelaware3
  • Fiscal year endsDecember 311
  • Industry code (SIC)2834 Pharmaceutical Preparations1
  • SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
  • Business address4275 Executive Square, Suite 300, La Jolla, CA 920371
  • Phone858-373-15001
  • Shares outstanding49,221,246 as of Aug 11, 202611
  • Public float$62.4M as of Jun 30, 20253
  • AuditorBDO USA, P.C., San Diego, California PCAOB ID 243; no auditor attestation of internal control over financial reporting3
  • On EDGAR sinceApr 8, 20031
  • Filings878 in all: 8-K (277), 4 (243), 10-Q (65), 3 (43), DEF 14A (23), 10-K (22), SC 13G/A (21), 424B5 (16)1
    All 42 form types

    ARS (13), CORRESP (12), EFFECT (12), SC 13G (12), UPLOAD (12), 425 (11), DEFA14A (11), S-3 (10), 4/A (8), 424B3 (7), S-8 (7), PRE 14A (5), S-1/A (5), S-1 (4), S-3/A (4), S-8 POS (4), SC 13D (4), SC 13D/A (4), S-4/A (3), 424B1 (2), 8-A12G (2), CT ORDER (2), PRER14A (2), REGDEX (2), 10-K/A (1), 10-Q/A (1), 3/A (1), 8-A12B (1), 8-A12G/A (1), CERTNAS (1), POS AM (1), REGDEX/A (1), S-4 (1), SCHEDULE 13D/A (1)

  • Latest filingsAnnual report (10-K) Mar 10, 2026
    Quarterly report (10-Q) Aug 13, 2026
    Proxy statement (DEF 14A) Apr 29, 2026
    Latest 8-K (8-K) Sep 28, 2026

Securities registered for trading

ClassSymbolExchange
Common Stock, par value $0.001 per shareMNOVThe Nasdaq Stock Market LLC

From the cover page of the 10-K filed Mar 10, 2026 (Section 12(b) of the Exchange Act).3

Risk factors and legal proceedings

The risks MEDICINOVA INC names in Item 1A of its 10-K filed Mar 10, 2026: 49 risks under these headings, as written.3

  • Risks Related to Our Business and Industry
  • We have incurred significant operating losses since our inception and expect that we will incur continued losses for the foreseeable future.
  • We will need to obtain additional funding to complete the development and any commercialization of our product candidates, if approved. If we fail to obtain this capital necessary to fund our operations, we will be forced to significantly delay, scale back or eliminate some or all of our clinical or regulatory activities or other operations.
  • We do not have any products that are approved for commercial sale and therefore currently generate no revenues from sales of any products and may never generate any revenues from product sales or be profitable in the foreseeable future, if ever.
  • We are largely dependent on the success of our MN-166 (ibudilast) and MN-001 (tipelukast) product candidates and we cannot be certain that these product candidates will receive regulatory approval or be successfully commercialized.
  • Because the results of early clinical trials are not necessarily predictive of future results, our product candidates we advance into clinical trials in any indication may not have favorable results in later clinical trials, if any, or receive regulatory approval.
  • Interim and preliminary "top-line" data from our clinical trials that we announce or publish from time to time may change as more patient data becomes available and is subject to audit and verification procedures that could result in material changes in the final data.
  • Our attempts to develop MN-001 (tipelukast) in Nonalcoholic Steatohepatitis (NASH) and Nonalcoholic Fatty Liver Disease (NAFLD) may detract from our efforts to develop other product candidates and may limit the effectiveness of our product development efforts as a whole.
  • In order to commercialize a therapeutic drug successfully, a product candidate must receive regulatory approval after the successful completion of clinical trials, which can be lengthy, complex and costly, have a high risk of failure and can be delayed or terminated at any time.
  • We are subject to stringent regulation of our product candidates, which could delay the development and commercialization of our product candidates.
  • Even if our product candidates receive regulatory approval, they may still face future development and regulatory difficulties.
  • We have received Fast Track and/or Orphan Drug designation for certain of our product candidates and may seek such designation, breakthrough therapy and/or priority review for other product candidates in the future. We may not receive such designations, and even if we do, we may not maintain such designations, and such designations may not lead to faster development, regulatory review or approval, and will not increase the likelihood that the product candidate will receive marketing approval.
The other 38 risks
  • Any product candidates that we advance into clinical trials may cause undesirable side effects or have other properties that could delay or prevent regulatory approval or commercialization or limit its commercial potential.
  • Delays in the commencement or completion of clinical trials, or suspension or termination of our clinical trials, could result in increased costs to us and delay or limit our ability to obtain regulatory approval for our product candidates.
  • The loss of any rights to develop and market any of our product candidates could significantly harm our business.
  • Our business could be adversely affected by the effects of health pandemics or epidemics in regions where we or third parties on which we rely have significant manufacturing facilities, concentrations of clinical trial sites or other business operations, which could materially affect our operations globally, including at our headquarters in San Diego and at our clinical trial sites, as well as the business or operations of our manufacturers, CROs or other third parties with whom we conduct business.
  • If our competitors develop and market products more rapidly than we do or that are more effective, safer or more affordable than our product candidates, our commercial opportunities may be negatively impacted.
  • We will depend on strategic collaborations with third party partners to develop and commercialize selected product candidates and will not have control over a number of key elements relating to the development and commercialization of these product candidates if we are able to achieve such third party arrangements.
  • We rely on third parties to conduct our clinical trials, and we may incur additional development costs, experience delays in the commencement and completion of clinical trials, and be unable to obtain regulatory approval for or commercialize our product candidates on our anticipated timeline if these third parties do not successfully carry out their contractual duties or meet expected deadlines, which may have an adverse effect on our business and prospects.
  • We rely, and intend to rely, on third party manufacturers to produce our product candidates, which may result in delays in our clinical trials and the commercialization of products, as well as increased costs.
  • We, or our third party manufacturers, may not be able to manufacture our product candidates in sufficient quality or commercial quantities, which would delay or prevent us from commercializing our product candidates.
  • Materials necessary to manufacture our product candidates may not be available on commercially reasonable terms, or at all, which may delay the development and commercialization of our product candidates.
  • Changes in methods of product candidate manufacturing or formulation may result in additional costs or delay.
  • Our product candidates, if approved for sale, may not gain acceptance among physicians, patients and the medical community, thereby limiting our potential to generate revenues.
  • If our products are not accepted by the market or if users of our products are unable to obtain adequate coverage of and reimbursement for our products from government and other third party payers, our revenues and profitability will suffer.
  • We are dependent on our management team, particularly our President and Chief Executive Officer, and our experienced scientific staff, and if we are unable to retain, motivate and attract key personnel, our product development programs may be delayed and we may be unable to develop successfully or commercialize our product candidates.
  • If we are unable to establish sales, marketing and distribution capabilities, whether independently or with third parties, we will be unable to commercialize our product candidates successfully.
  • Health care reform measures could adversely affect our business.
  • Any clinical trial programs, marketing, or research collaborations in the European Economic Area (EEA) will subject us to the General Data Protection Regulation, including as implemented in the UK (GDPR).
  • We are subject to environmental, health and safety laws and regulations, and we may become exposed to liability and substantial expenses in connection with environmental compliance or remediation activities.
  • We are subject to certain United States and foreign anti-corruption, anti-money laundering, export control, sanctions, and other trade laws and regulations. We can face serious consequences for violations.
  • We may be sued for product liability, which could result in substantial liabilities that exceed our available resources and damage our reputation.
  • We expect that our results of operations will fluctuate, which may make it difficult to predict our future performance from period to period.
  • We will continue to incur significant increased costs as a result of operating as a public company, and our management will be required to devote substantial time to new compliance initiatives.
  • We, or our third party CROs or other contractors or consultants, may be subject to information technology systems failures, network disruptions, breaches in data security and computer crime and cyber-attacks, which could result in a material disruption of our product candidates' development programs, compromise sensitive information related to our business or prevent us from accessing critical information, potentially exposing us to liability or otherwise adversely affecting our business.
  • Macroeconomic pressures, including those resulting from ongoing geopolitical matters, tariffs, unfavorable market conditions, health epidemics, and regulatory and policy changes, may have an adverse impact on our business, financial results, stock price and results of operations as well as the business of our current and potential customers.
  • We may be adversely affected by the effects of inflation, including as a result of increased tariffs.
  • A variety of risks associated with operating our business and marketing our products internationally could materially adversely affect our business.
  • Risks Related to Our Intellectual Property
  • Our ability to compete may decline if we do not adequately protect our proprietary rights.
  • Changes in patent law in the United States and other jurisdictions could diminish the value of patents in general, thereby impairing our ability to protect our product candidates.
  • Confidentiality agreements with employees and others may not adequately prevent disclosure of our trade secrets and other proprietary information and may not adequately protect our intellectual property, which could limit our ability to compete.
  • A dispute concerning the infringement or misappropriation of our proprietary rights or the proprietary rights of others could be time consuming and costly, and an unfavorable outcome could harm our business.
  • We may be subject to claims that our employees have wrongfully used or disclosed alleged trade secrets of their former employers.
  • Risks Related to the Securities Markets and Investment in Our Common Stock
  • The stock price of our common stock may be volatile or decline regardless of our operating performance, and you may not be able to resell our shares at a profit or at all.
  • Our common stock may be delisted from the Nasdaq Global Market or the Standard Market of the Tokyo Stock Exchange.
  • We may become involved in securities class action litigation that could divert management’s attention and harm our business.
  • Future sales of our common stock may cause our stock price to decline and may make it difficult for us to raise additional capital or for you to sell your shares.
  • If our estimates or judgments relating to our critical accounting policies are based on assumptions that change or prove to be incorrect, our results of operation could fall below the expectations of securities analysts and investors, resulting in a decline in the market price of our common stock.
  • We are a “smaller reporting company” and may take advantage of certain scaled disclosures available to us. We cannot be certain if the reduced reporting requirements applicable to smaller reporting companies will make our common stock less attractive to investors.
  • Anti-takeover provisions in our charter documents and under Delaware law may make an acquisition of us more complicated and the removal and replacement of our directors and management more difficult.

Legal proceedings

We are not involved in any material legal proceedings as of the date of this report. We may become involved in various disputes and legal proceedings which arise in the ordinary course of business. Our assessment of the likely impact of our pending litigation may change over time. An adverse result in any of these matters may occur which could harm our business and result in a material liability.

The opening of Item 3, Legal Proceedings.3

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