Overview
- TickerREVB on Nasdaq2
- IndustryPharmaceutical Preparations2
- HeadquartersSan Diego, United States2
- Incorporated inDE3
- Business address4660 Lajolla Village Drive, Suite 100, San Diego, Ca 921223
- Filer categoryNon-accelerated filer, Smaller reporting company3
- Legal formCorporation2
- LEI549300UKS15BEXENY6152
- StatusActive2
- LEI statusLapsed (not renewed)2
- Registered addressC/O HARVARD BUSINESS SERVICES, INC., 19958 Lewes, United States2
- Registered withDivision of Corporations, Department of State, 77138942
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Revelation is a clinical-stage life science company that is focused on rebalancing inflammation to optimize health using its proprietary formulation Gemini. We have multiple ongoing programs to evaluate Gemini, including GEM-AKI as a treatment for acute kidney injury (“AKI”) and GEM-CKD as a treatment for chronic kidney disease (“CKD”). The Company was incorporated in the state of Delaware on November 20, 2019 (originally as Petra Acquisition, Inc.) and is based in San Diego, California.4 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.8
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Research and development | $4.1M | $3.5M |
| General and administrative | $5.0M | $4.4M |
| Total operating expenses | $9.1M | $8.0M |
| Loss from operations | -$9.1M | -$8.0M |
| Change in fair value of warrant liability | $2.2K | $81.4K |
| Other income (expense), net | $155.0K | -$7.1M |
| Total other income (expense), net | $157.2K | -$7.1M |
| Net loss | -$8.9M | -$15.0M |
| Deemed dividends | -$6.0M | |
| Net loss attributable to common stockholders | -$14.9M | -$15.0M |
| Net loss per share, basic | -$23.95 | -$1,052.16 |
| Net loss per share, diluted | -$23.95 | -$1,052.16 |
| Weighted-average shares used to compute net loss per share, basic | 620.8K shares | 14.3K shares |
| Weighted-average shares used to compute net loss per share, diluted | 620.8K shares | 14.3K shares |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 3 fiscal years (annual) or 3 quarters (quarterly), latest first.8
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Cash and cash equivalents | $10.7M | $6.5M | |
| Prepaid expenses and other current assets | $111.3K | $66.7K | |
| Total current assets | $10.8M | $6.6M | |
| Property and equipment, net | $18.1K | $56.3K | |
| Operating lease right-of-use asset | $722.3K | $0 | |
| Other assets | $30.9K | $0 | |
| Total assets | $11.6M | $6.6M | |
| Accounts payable | $577.5K | $783.6K | |
| Accrued expenses | $1.4M | $1.1M | |
| Operating lease liability | $23.0K | $0 | |
| Total current liabilities | $2.0M | $1.9M | |
| Operating lease liability, net of current portion | $723.8K | $0 | |
| Total liabilities | $2.7M | $1.9M | |
| Common Stock, $0.001 par value; 500,000,000 shares authorized at December 31, 2025 and December 31, 2024 and 1,583,969 and 43,526 issued and outstanding at December 31, 2025 and December 31, 2024, respectively | $1.6K | $44 | |
| Additional paid-in-capital | $58.3M | $45.2M | |
| Accumulated deficit | -$49.4M | -$40.5M | |
| Total stockholders' equity | $8.9M | $4.7M | $6.6M |
| Total liabilities and stockholders' equity | $11.6M | $6.6M | |
| Common stock, par value (in Dollars per share) | $0.00 | $0.00 | |
| Common stock, shares authorized | 500.0M shares | 500.0M shares | |
| Common stock, shares issued | 1.6M shares | 43.5K shares | |
| Common stock, shares outstanding | 1.6M shares | 43.5K shares |
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Cash and cash equivalents | $10.7M | $6.5M | |
| Prepaid expenses and other current assets | $111.3K | $66.7K | |
| Total current assets | $10.8M | $6.6M | |
| Property and equipment, net | $18.1K | $56.3K | |
| Operating lease right-of-use asset | $722.3K | $0 | |
| Other assets | $30.9K | $0 | |
| Total assets | $11.6M | $6.6M | |
| Accounts payable | $577.5K | $783.6K | |
| Accrued expenses | $1.4M | $1.1M | |
| Operating lease liability | $23.0K | $0 | |
| Total current liabilities | $2.0M | $1.9M | |
| Operating lease liability, net of current portion | $723.8K | $0 | |
| Total liabilities | $2.7M | $1.9M | |
| Common Stock, $0.001 par value; 500,000,000 shares authorized at December 31, 2025 and December 31, 2024 and 1,583,969 and 43,526 issued and outstanding at December 31, 2025 and December 31, 2024, respectively | $1.6K | $44 | |
| Additional paid-in-capital | $58.3M | $45.2M | |
| Accumulated deficit | -$49.4M | -$40.5M | |
| Total stockholders' equity | $8.9M | $4.7M | $6.6M |
| Total liabilities and stockholders' equity | $11.6M | $6.6M | |
| Common stock, par value (in Dollars per share) | $0.00 | $0.00 | |
| Common stock, shares authorized | 500.0M shares | 500.0M shares | |
| Common stock, shares issued | 1.6M shares | 43.5K shares | |
| Common stock, shares outstanding | 1.6M shares | 43.5K shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.8
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$8.9M | -$15.0M |
| Stock-based compensation expense | $595.4K | $168.8K |
| Depreciation expense | $27.1K | $27.9K |
| Non-cash lease expense | $18.6K | |
| Loss on disposal of equipment | $11.2K | |
| Change in fair value of warrant liability | -$2.2K | -$81.4K |
| Issuance of common stock for services | $25.0K | |
| Prepaid expenses and other current assets | -$44.6K | $18.0K |
| Deferred offering costs | $71.1K | |
| Other assets | -$30.9K | |
| Accounts payable | -$206.1K | -$576.3K |
| Accrued expenses | $269.8K | -$2.9M |
| Operating lease liability | $5.9K | |
| Net cash used in operating activities | -$8.3M | -$18.3M |
| Purchase of property and equipment | -$19.2K | |
| Net cash used in investing activities | -$19.2K | |
| Net cash provided by financing activities | $12.5M | $12.8M |
| Net increase (decrease) in cash and cash equivalents | $4.2M | -$5.5M |
| Deemed dividend for exercise price reductions of warrants | $6.0M | |
| Operating lease right-of-use asset exchanged for lease liability | $740.9K |
No quarter-by-quarter statement was filed.
Corporate structure
REVELATION BIOSCIENCES, INC. sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.
Major holders of REVELATION BIOSCIENCES, INC.
- ARMISTICE CAPITAL, LLC Filed SCHEDULE 13G/A on REVELATION BIOSCIENCES, INC., latest Aug 14, 2026 (4 filings since Nov 14, 2025)
- SABBY MANAGEMENT, LLC Filed SCHEDULE 13G on REVELATION BIOSCIENCES, INC., latest Jan 20, 2026 (3 filings since Jan 3, 2024)
- Lind Global Fund II LP Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Feb 13, 2024 (2 filings since Feb 21, 2023)
- AXA IM Prime Impact Master Fund I SCA SICAV-RAIF Filed SCHEDULE 13G/A on REVELATION BIOSCIENCES, INC., latest Feb 12, 2024 (2 filings since Feb 14, 2023)
- INTRACOASTAL CAPITAL, LLC Filed SC 13G on REVELATION BIOSCIENCES, INC., latest Feb 21, 2023
- Weiss Asset Management LP Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Feb 6, 2023 (2 filings since Feb 9, 2022)
- Linden Capital L.P. Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Jan 31, 2023 (2 filings since Jan 20, 2022)
- METEORA CAPITAL, LLC Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Aug 17, 2022 (2 filings since Mar 24, 2022)
- Karpus Management, Inc. Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Mar 10, 2022 (2 filings since Feb 14, 2022)
- George F. Tidmarsh Filed SC 13D on REVELATION BIOSCIENCES, INC., latest Feb 15, 2022
- GLAZER CAPITAL, LLC Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Feb 14, 2022 (2 filings since Oct 12, 2021)
- Polar Asset Management Partners Inc. Filed SC 13G/A on REVELATION BIOSCIENCES, INC., latest Feb 11, 2022
- REVELATION BIOSCIENCES, INC. San Diego, California, United States
Built from parent and subsidiary links from GLEIF, the Global Legal Entity Identifier Foundation (CC0); major holders from Schedules 13D and 13G. Each entity in the chart links to its source.
What it owns
What REVELATION BIOSCIENCES, INC. reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.
Property and equipment
| Item | Latest | A year before | Change |
|---|---|---|---|
| Machinery and equipment | $117.1K8 Dec 31, 2025 | $151.1K8 Dec 31, 2024 | −22.5% |
| Property and equipment, before depreciation | $117.1K8 Dec 31, 2025 | $151.1K8 Dec 31, 2024 | −22.5% |
| Accumulated depreciation | $99.0K8 Dec 31, 2025 | $94.8K8 Dec 31, 2024 | +4.4% |
| Property and equipment, net | $18.1K8 Dec 31, 2025 | $56.3K8 Dec 31, 2024 | −67.9% |
| Operating-lease assets (leased space) | $722.3K8 Dec 31, 2025 | $08 Dec 31, 2024 |
Investments
Properties, in its own words
Our corporate headquarters is located at 4660 La Jolla Village Dr., Suite 100, San Diego, California, where we currently have access to office space on an as-needed basis. We lease laboratory and office space at 5555 Oberlin Drive, Suite 100, San Diego, California, which consists of approximately 5,381 square feet. The lease expires on November 30, 2028. We believe that our current space is adequate for our needs.
Item 2 of the 10-K filed Feb 26, 2026.4
Leadership
Who has led REVELATION BIOSCIENCES, INC., and when. Pick a name to see everywhere that person has worked.
Chief financial officer
- Chief executive officerJames Rolke Jan 20, 2022 to now14
- Chief executive officerAndreas Typaldos Oct 21, 2020 to Dec 31, 202015
- Chief executive officerSean H. Fitzpatrick Dec 31, 2020 to Dec 31, 202016
- Chief financial officerChester Stanley Zygmont Iii. Jan 20, 2022 to now17
- Chief financial officerSean H. Fitzpatrick Oct 13, 2020 to Oct 20, 202018
Board members and other officers (13)
- Board memberLakhmir S. Chawla Oct 2, 2023 to now19
- Board memberCurt H. Labelle Jan 20, 2022 to Apr 18, 202320
- Board memberGeorge F. Tidmarsh Jan 20, 2022 to Feb 13, 202521
- Board memberJames Rolke Jan 20, 2022 to now14
- Board memberJennifer Carver Jan 20, 2022 to now22
- Board memberJess Roper Jan 20, 2022 to now23
- Board memberAnthony Hayes Oct 9, 2020 to Oct 9, 202024
- Board memberBarry Dennis Oct 9, 2020 to Oct 9, 202025
- Board memberDavid Dobkin Oct 9, 2020 to Oct 9, 202026
- Board memberKimon Angelides Oct 9, 2020 to Oct 9, 202027
- Board memberRobert D. Nicholson Oct 9, 2020 to Oct 9, 202028
- Board memberSean H. Fitzpatrick Oct 13, 2020 to Dec 31, 202018
- Board memberAndreas Typaldos Oct 21, 2020 to Dec 31, 202015
Former names
- Petra Acquisition Inc.May 14, 2020 to Jan 11, 20223
Timeline
- Aug 19, 20268-K Executive or director change29
- Aug 6, 20268-K Results of operations30
- Jul 13, 20268-K Entered a material agreement; Change to shareholders' rights; Bylaws or fiscal year changed31
- Jun 24, 20268-K Executive or director change; Bylaws or fiscal year changed; Shareholder vote32
- Jun 1, 20268-K Other events33
- May 7, 20268-K Results of operations34
- Mar 19, 20268-K Change to shareholders' rights; Shareholder vote35
- Feb 26, 20268-K Results of operations36
- Jan 29, 20268-K Entered a material agreement; Unregistered sale of shares; Change to shareholders' rights37
- Jan 22, 20268-K Other events38
- Dec 3, 20258-K Change to shareholders' rights; Shareholder vote; Other events39
- Nov 6, 20258-K Results of operations40
- Jan 20, 2022New chief executive James Rolke becomes CEO14
- Dec 31, 2020New chief executive Sean H. Fitzpatrick becomes CEO16
- Oct 21, 2020New chief executive Andreas Typaldos becomes CEO15
- Nov 20, 2019Founded REVELATION BIOSCIENCES, INC. is founded2
Calendar
Coming up
- Oct 20, 2026Split Reverse split 1:7.41
- Nov 5, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported ($7.08) a share, on Nov 6, 2025.42
When it reported results
- Aug 6, 2026Reported quarterly or annual results30
- May 7, 2026Reported quarterly or annual results34
- Feb 26, 2026Reported quarterly or annual results36
- Nov 6, 2025Reported quarterly or annual results40
- Aug 8, 2025Reported quarterly or annual results43
- May 8, 2025Reported quarterly or annual results44
- Mar 6, 2025Reported quarterly or annual results45
- Nov 8, 2024Reported quarterly or annual results46
Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar
Filings
327 filings to the SEC since October 2021: 6 annual reports, 17 quarterly reports, 89 major events, 54 insider forms, 27 large holders, 134 other. The latest 20:
- Aug 19, 20268-K EDGAR
- Aug 18, 20264 EDGAR
- Aug 18, 20264 EDGAR
- Aug 18, 20264 EDGAR
- Aug 18, 20264 EDGAR
- Aug 18, 20264 EDGAR
- Aug 14, 2026SCHEDULE 13G/A EDGAR
- Aug 6, 20268-K EDGAR
- Aug 6, 202610-Q EDGAR
- Jul 13, 20268-A12B EDGAR
- Jul 13, 20268-K EDGAR
- Jun 24, 20268-K EDGAR
- Jun 1, 20268-K EDGAR
- May 15, 2026SCHEDULE 13G EDGAR
- May 11, 2026ARS EDGAR
- May 11, 2026DEF 14A EDGAR
- May 7, 20268-K EDGAR
- May 7, 202610-Q EDGAR
- May 1, 20264 EDGAR
- May 1, 20264 EDGAR
The 327 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
16 open-market trades by officers, directors and large owners since October 2021: 9 buys and 7 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Dec 8, 2023 | TIDMARSH GEORGE FDirector | Sale | 27,771 | $0.52 | $14.4K | Form 4 |
| Oct 16, 2023 | TIDMARSH GEORGE FDirector | Sale | 1,845 | $0.65 | $1.2K | Form 4 |
| Oct 16, 2023 | TIDMARSH GEORGE FDirector | Sale | 10,957 | $0.66 | $7.2K | Form 4 |
| Sep 28, 2023 | TIDMARSH GEORGE FDirector | Sale | 1,429 | $0.69 | $986 | Form 4 |
| Sep 18, 2023 | TIDMARSH GEORGE FDirector | Sale | 4,000 | $0.74 | $3.0K | Form 4 |
| Sep 15, 2023 | TIDMARSH GEORGE FDirector | Sale | 9,500 | $0.73 | $6.9K | Form 4 |
| Sep 14, 2023 | TIDMARSH GEORGE FDirector | Sale | 12,000 | $0.75 | $9.0K | Form 4 |
| Apr 18, 2023 | TIDMARSH GEORGE FDirector | Buy | 25,000 | $1.16 | $29.0K | Form 4 |
| Apr 17, 2023 | TIDMARSH GEORGE FDirector | Buy | 26,500 | $1.16 | $30.7K | Form 4 |
| Feb 25, 2022 | TIDMARSH GEORGE FDirector | Buy | 20,000 | $1.60 | $32.0K | Form 4 |
| Feb 9, 2022 | TIDMARSH GEORGE FDirector | Buy | 30,000 | $2.55 | $76.5K | Form 4 |
| Feb 8, 2022 | TIDMARSH GEORGE FDirector | Buy | 1,000 | $2.54 | $2.5K | Form 4 |
| Feb 7, 2022 | TIDMARSH GEORGE FDirector | Buy | 42,100 | $2.61 | $109.9K | Form 4 |
| Feb 7, 2022 | TIDMARSH GEORGE FDirector | Buy | 42,100 | $2.61 | $109.9K | Form 4 |
| Feb 4, 2022 | TIDMARSH GEORGE FDirector | Buy | 9,900 | $2.34 | $23.1K | Form 4 |
| Feb 4, 2022 | TIDMARSH GEORGE FDirector | Buy | 7,900 | $2.31 | $18.2K | Form 4 |
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- ARMISTICE CAPITAL, LLCSCHEDULE 13G/A, 4 filings Nov 14, 2025 to Aug 14, 202647
- SABBY MANAGEMENT, LLCSCHEDULE 13G, 3 filings Jan 3, 2024 to Jan 20, 202648
- Lind Global Fund II LPSC 13G/A, 2 filings Feb 21, 2023 to Feb 13, 202449
- AXA IM Prime Impact Master Fund I SCA SICAV-RAIFSCHEDULE 13G/A, 2 filings Feb 14, 2023 to Feb 12, 202450
- INTRACOASTAL CAPITAL, LLCSC 13G, 1 filing Feb 21, 202351
- Weiss Asset Management LPSC 13G/A, 2 filings Feb 9, 2022 to Feb 6, 202352
- Linden Capital L.P.SC 13G/A, 2 filings Jan 20, 2022 to Jan 31, 202353
- METEORA CAPITAL, LLCSC 13G/A, 2 filings Mar 24, 2022 to Aug 17, 202254
- Karpus Management, Inc.SC 13G/A, 2 filings Feb 14, 2022 to Mar 10, 202255
- George F. TidmarshSC 13D, 1 filing Feb 15, 202256
- GLAZER CAPITAL, LLCSC 13G/A, 2 filings Oct 12, 2021 to Feb 14, 202257
- Polar Asset Management Partners Inc.SC 13G/A, 1 filing Feb 11, 202258
- Hudson Bay Capital Management LPSC 13G/A, 1 filing Feb 4, 202259
- Lawrence FeisSC 13G/A, 2 filings Oct 12, 2021 to Jan 11, 202260
Executive pay
What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.
| Year | Executive | Age | Salary | Total pay |
|---|---|---|---|---|
| 2025 | James Rolke | 57 | $589.0K | $1.5M61 |
| 2025 | Chester S. ZygmontIII | 45 | $425.2K | $1.2M61 |
| 2024 | ChairmanDirector, and CEO | $561.0K | $813.2K61 | |
| 2024 | CFO | $405.0K | $564.0K61 |
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| Sabby Management, LLC | 210,582 | $216.9K | 1.8% | +111,150 |
| Citadel Advisors LLC | 38,579 | $39.7K | 0.0% | New |
| Geode Capital Management, LLC | 17,192 | $17.7K | 0.0% | −26,003 |
| Vanguard Fiduciary Trust Co | 13,127 | $13.5K | 0.0% | No change |
| Tower Research Capital LLC (TRC) | 6,528 | $6.7K | 0.0% | +2,454 |
| Royal Bank Of Canada | 747 | $1.0K | 0.0% | No change |
| SBI Securities Co., Ltd. | 344 | $354 | 0.0% | No change |
| Barclays PLC | 168 | $173 | 0.0% | New |
| Hrt Financial LP | 16,978 | $17 | 0.0% | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 9 | $9 | 0.0% | No change |
| Caitong International Asset Management Co., Ltd | 1 | $1 | 0.0% | No change |
| Fmr LLC | 0 | $0 | 0.0% | New |
13F reports cover disclosed long positions in U.S. stocks only.
SEC filer profile
How REVELATION BIOSCIENCES, INC. is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.
- Name on EDGARREVELATION BIOSCIENCES, INC.1
- CIK0001810560
- Employer ID (EIN)84-38984664
- Filer statusNon-accelerated filer not an emerging growth company; a smaller reporting company; not a shell company4
- Incorporated inDelaware4
- Fiscal year endsDecember 311
- Industry code (SIC)2834 Pharmaceutical Preparations1
- SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
- Business address4660 Lajolla Village Drive, Suite 100, San Diego, CA 921221
- Phone650-800-37171
- Shares outstanding3,983,416 as of Aug 3, 202612
- Public float$3.4M as of Jun 30, 20254
- AuditorBaker Tilly US, LLP, San Diego, CA PCAOB ID 23; no auditor attestation of internal control over financial reporting4
- On EDGAR sinceMay 14, 20201
- Filings387 in all: 8-K (96), 4 (51), CORRESP (26), 10-Q (18), 3 (17), UPLOAD (16), SC 13G/A (15), EFFECT (14)1
All 41 form types
SC 13G (14), S-1/A (13), 424B3 (11), DEF 14A (11), PRE 14A (11), S-1 (8), DEFA14A (7), 10-K (6), 425 (5), S-3 (5), S-8 (5), SCHEDULE 13G/A (4), 8-K/A (3), NT 10-Q (3), S-4/A (3), SCHEDULE 13G (3), 10-K/A (2), 10-Q/A (2), 8-A12B (2), DRS (2), S-3/A (2), 144 (1), 25-NSE (1), 4/A (1), 424B4 (1), 5 (1), ARS (1), CERT (1), DEFR14A (1), NT 10-K (1), S-1MEF (1), S-4 (1), SC 13D (1)
- Latest filingsAnnual report (10-K) Feb 26, 2026
Quarterly report (10-Q) Aug 6, 2026
Proxy statement (DEF 14A) May 11, 2026
Latest 8-K (8-K) Aug 19, 2026
Securities registered for trading
| Class | Symbol | Exchange |
|---|---|---|
| Common stock, par value $0.001 per share | REVB | Nasdaq |
From the cover page of the 10-K filed Feb 26, 2026 (Section 12(b) of the Exchange Act).4
Risk factors and legal proceedings
The risks REVELATION BIOSCIENCES, INC. names in Item 1A of its 10-K filed Feb 26, 2026: 64 risks under these headings, as written.4
- Risks Related to Our Business
- Although our financial statements have been prepared on a going concern basis, we have a limited operating history and no products approved for commercial sale. We have incurred net losses since our inception, we anticipate that we will continue to incur significant losses for the foreseeable future, and even if we were to generate revenue, we may never achieve or maintain profitability.
- Unfavorable global economic conditions, including any adverse macroeconomic conditions or geopolitical events affecting the financial services industry, could adversely affect our business, financial condition, results of operations or liquidity, either directly or through adverse impacts on certain of the third parties on which we rely to conduct certain aspects of our preclinical studies or clinical trials.
- Risks Related to the Product Development, Regulatory Approval, Manufacturing andCommercialization of Our Product Candidates
- If preclinical studies or clinical studies for our Product Candidates are unsuccessful or delayed, we will be unable to meet our future development goals.
- Drug development involves a lengthy and expensive process with uncertain timelines and uncertain outcomes, and the results of prior preclinical or clinical studies are not necessarily predictive of our future results. Our clinical studies may fail to adequately demonstrate the safety and efficacy of our Product Candidates or any future product candidates.
- The Clinical Studies of our Product Candidates’ have been and are planned to be conducted outside the United States, and the FDA or comparable foreign regulatory authorities may modify their regulatory pathway or conditions previously agreed upon, or may not accept data from such studies.
- As an organization, we have never conducted pivotal clinical studies, and we may be unable to do so for any product candidates we may develop.
- We may find it difficult to enroll patients in our clinical studies, which could delay or prevent us from proceeding with clinical studies.
- Our Product Candidates and the administration of our Product Candidates may cause undesirable side effects or have other properties that could delay or prevent their regulatory approval, limit the commercial profile of an approved label or result in significant negative consequences following marketing approval, if any.
- Interim, topline and preliminary data from our clinical studies that we announce or publish from time to time may change as more patient data become available and are subject to audit and verification procedures that could result in material changes in the final data.
- Even if we complete the necessary clinical studies, we cannot predict when, or if, we will obtain regulatory approval to commercialize any of our Product Candidates, and the approval may be for a more narrow indication than we seek or be subject to other limitations or restrictions that limit its commercial profile.
The other 53 risks
- Significant reductions in FDA staffing and changes in federal regulatory policy may delay or adversely affect the approval and commercialization of our Product Candidates.
- Our business depends on the success of our Product Candidates, including obtaining regulatory approval to market our Product Candidates in the United States and/or other major foreign markets such as the EU.
- Disruptions at the FDA and other national and foreign government authorities caused by funding shortages or global health concerns could hinder their ability to hire, retain or deploy key leadership and other personnel, or otherwise prevent new or modified products from being developed, approved or commercialized in a timely manner or at all, which could negatively impact our business.
- Even if we obtain regulatory approval for a product candidate, our products and business will remain subject to ongoing regulatory obligations and review.
- If one or more of our Product Candidates is approved for marketing in the United States or other countries, we may be subject, directly or indirectly, to United States or other countries equivalent federal and state healthcare fraud and abuse laws, false claims laws, physician payment transparency laws and health information privacy and security laws. If we are unable to comply, or have not fully complied, with such laws, we could face substantial penalties.
- Legislative or regulatory healthcare reforms in the United States or other countries may make it more difficult and costly for us to obtain regulatory clearance or approval of our Product Candidates and to produce, market and distribute our Product Candidates after clearance or approval is obtained.
- We face intense competition in an environment of rapid technological change and the possibility that our competitors may develop products and drug delivery systems that are similar, more advanced or more effective than ours, which may adversely affect our financial condition and our ability to successfully market or commercialize our Product Candidates.
- Changes in U.S. and international trade policies may adversely impact our business and operating results.
- Artificial intelligence is playing an increasingly important role in biotechnology which may have an effect on us.
- Risks Related to our Reliance on Third Parties
- We rely on third parties to conduct certain elements of our preclinical and clinical studies and perform other tasks for us. If these third parties do not successfully carry out their contractual duties, meet expected deadlines or comply with regulatory requirements, we may not be able to obtain regulatory approval for or commercialize our Product Candidates.
- We rely on third parties to manufacture the raw materials, including the active pharmaceutical ingredients that we use to create our therapeutic product candidate, and to manufacture the diagnostic devices, including the antibodies used for testing. Our business could be harmed if existing and prospective third parties fail to provide us with sufficient quantities of these materials and products or fail to do so at acceptable quality levels or prices.
- We may not be able to obtain and maintain the third-party relationships that are necessary to develop, commercialize and manufacture some or all of our Product Candidates.
- Risks Related to Our Intellectual Property
- If we are unable to obtain and maintain effective patent rights for our Product Candidates or any future product candidates, we may not be able to compete effectively in our markets. If we are unable to protect the confidentiality of our trade secrets or know-how, such proprietary information may be used by others to compete against us.
- We may not be able to protect our intellectual property rights throughout the world.
- We may not have sufficient patent lifespan to effectively protect our products and business.
- If we are unable to maintain effective proprietary rights for our Product Candidates or any future product candidates, we may not be able to compete effectively in our markets.
- We may be involved in lawsuits to protect or enforce our intellectual property, which could be expensive, time-consuming and unsuccessful.
- We may infringe the intellectual property rights of others, which could increase our costs and delay or prevent our development efforts.
- Changes in United States and international patent law could diminish the value of patents in general, thereby impairing our ability to protect our products.
- Our inability to protect our trade secrets would harm our business and competitive position.
- Intellectual property rights do not necessarily address all potential threats.
- If our trademarks and trade names are not maintained and adequately protected, we may not be able to build name recognition in our markets of interest, and our business may be adversely affected.
- Risks Related to Our Business Operations
- Our future success depends in part on our ability to retain our senior management team, directors and other key employees and to attract, retain and motivate other qualified personnel.
- We will need to expand our organization, and we may experience difficulties in managing this growth, which could disrupt our operations.
- We may not be successful in our efforts to identify, discover or license additional product candidates.
- If we fail to comply with environmental, health and safety laws and regulations, we could become subject to fines or penalties or incur costs that could have a material adverse effect on the success of our business.
- Ongoing healthcare legislative and regulatory reform measures may adversely affect our business, results of operations and financial condition.
- Risks Related to Commercialization of Our Product Candidates
- As we evolve from a company that is primarily involved in clinical development to a company that is also involved in commercialization, we may encounter difficulties in expanding our operations successfully.
- We may seek to establish commercial collaborations for our Product Candidates and future product candidates, and, if we are not able to establish them on commercially reasonable terms, we may have to alter our development plans.
- We currently have no Product Candidates approved for marketing. We do not have a marketing and sales organization. If we are unable to establish sales and marketing capabilities or enter into agreements with third parties to market and sell our Product Candidates, we may be unable to generate any product revenue.
- It may be difficult for us to profitably sell our Product Candidates, if and when approved, if coverage and reimbursement for these Product Candidates are limited by government authorities and/or third-party payor policies.
- Our business entails a significant risk of clinical study and/or product liability and our ability to obtain sufficient insurance coverage could have a material effect on our business, financial condition, results of operations or prospects.
- Product liability lawsuits against us could cause us to incur substantial liabilities and to limit commercialization of any products that we may develop.
- Our employees, contractors, vendors, principal investigators, consultants and future partners may engage in misconduct or other improper activities, including noncompliance with regulatory standards and requirements and insider trading.
- Our business operations and relationships with investigators, healthcare professionals, consultants, third-party payors, patient organizations and customers are subject to broadly applicable healthcare regulatory laws, which could expose us to penalties.
- Data collection is governed by restrictive regulations governing the collection, use, processing and cross-border transfer of personal information.
- Unstable market and economic conditions may have serious adverse consequences on our business and financial condition.
- We are subject to U.S. and certain foreign export and import controls, sanctions, embargoes, anti-corruption laws, and anti-money laundering laws and regulations. Compliance with these legal standards could impair our ability to compete in domestic and international markets. We can face criminal liability and other serious consequences for violations, which can harm our business.
- Changes in our effective income tax rate could adversely affect our results of operations.
- Our future growth may depend, in part, on our ability to penetrate foreign markets, where we would be subject to additional regulatory burdens and other risks and uncertainties.
- We face the risk of product liability claims and may not be able to obtain insurance.
- Our insurance policies are expensive and protect us only from some business risks, which will leave us exposed to significant uninsured liabilities.
- We have no current plans to pay dividends on our shares of common stock.
- Loss of Emerging Grown Company Status
- Our common stock price may be volatile and as a result you could lose all or part of your investment.
- Potential future sales pursuant to registration rights granted by the Company and under Rule 144 may depress the market price for our shares of common stock.
- FINRA has adopted sales practice requirements, which may also limit a stockholder’s ability to buy and sell our common stock.
- We face risks related to compliance with corporate governance laws and financial reporting standards.
- Anti-takeover provisions contained in our Charter and bylaws, as well as provisions of Delaware law, could impair a takeover attempt.
- Our Charter provides that the Court of Chancery of the State of Delaware and the federal district courts of the United States of America will be the exclusive forums for substantially all disputes between us and our stockholders, which could limit our stockholders’ ability to obtain a favorable judicial forum for disputes with us or our directors, officers, or employees.
- If Revelation is not able to comply with the applicable continued listing requirements or standards of Nasdaq, Nasdaq could delist our common stock.
- Revelation will continue to incur significant increased expenses and administrative burdens as a public company, which could negatively impact its business, financial condition and results of operations.
- Revelation’s business and operations could be negatively affected if it becomes subject to any securities litigation or stockholder activism, which could cause Revelation to incur significant expense, hinder execution of business and growth strategy and impact its stock price.
- Our common stock warrants may be accounted for as warrant liabilities and the changes in value of our warrants could have a material effect on our financial results.
Sources
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- 14SEC EDGARJames Rolke, Chief executive officer
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- 19SEC EDGARLakhmir S. Chawla, Board member
- 20SEC EDGARCurt H. Labelle, Board member
- 21SEC EDGARGeorge F. Tidmarsh, Board member
- 22SEC EDGARJennifer Carver, Board member
- 23SEC EDGARJess Roper, Board member
- 24SEC EDGARAnthony Hayes, Board member
- 25SEC EDGARBarry Dennis, Board member
- 26SEC EDGARDavid Dobkin, Board member
- 27SEC EDGARKimon Angelides, Board member
- 28SEC EDGARRobert D. Nicholson, Board member
- 29SEC EDGARExecutive or director change
- 30SEC EDGARResults of operations
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- 33SEC EDGAROther events
- 34SEC EDGARResults of operations
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- 36SEC EDGARResults of operations
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- 38SEC EDGAROther events
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- 40SEC EDGARResults of operations
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