SUPN on Nasdaq

SUPERNUS PHARMACEUTICALS, INC.

SUPERNUS PHARMACEUTICALS, INC. is an American pharmaceutical preparations company based in Rockville.2 Its shares trade on Nasdaq under the symbol SUPN.2

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Last updated Oct 21, 2026.

Overview

Compare with Amphastar Pharmaceuticals, Inc., Pacira BioSciences, Inc. or Emergent BioSolutions, or pick any stock.

  • TickerSUPN on Nasdaq2
  • IndustryPharmaceutical Preparations2
  • HeadquartersRockville, United States2
  • Incorporated inDE3
  • Business address9715 Key West Avenue, Rockville, Md 208503
  • Filer categoryLarge accelerated filer3
  • Legal formCorporation2
  • LEI549300GRM36VBKISYJ582
  • StatusActive2
  • LEI statusLapsed (not renewed)2
  • Registered addressC/O CORPORATION SERVICE COMPANY, 19808 Wilmington, United States2
  • Registered withDivision of Corporations, Department of State, 39475842

Supernus Pharmaceuticals, Inc. (the Company) is a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases. The Company's diverse neuroscience portfolio includes approved treatments for attention-deficit hyperactivity disorder (ADHD), dyskinesia in Parkinson's Disease (PD) patients receiving levodopa-based therapy, hypomobility in PD, postpartum depression (PPD), epilepsy, migraine, cervical dystonia, and chronic sialorrhea. The Company is developing a broad range of novel product candidates for CNS disorders.5 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-8.7%Operating margin6
-5.4%Net margin6
8.6%Revenue growth, 20256
-3.6%Return on equity6
$46.0MFree cash flow6

What sells

Revenue by product, business segment and region, as the company reports it to the SEC.

Products and services

Qelbree brought in 42% of the revenue SUPERNUS PHARMACEUTICALS, INC. broke down this way in fiscal 2025.

  1. Qelbree$304.7M642%up 26% from 2024
  2. Gocovri$146.8M620%up 12% from 2024
  3. Collaboration Revenue$53.0M67%
  4. Apokyn$47.8M67%down 35% from 2024
  5. Trokendi Xr$42.4M66%down 33% from 2024
  6. Oxtellar X R$40.7M66%down 59% from 2024
  7. Royalty, License And Other Revenue$39.4M65%up 63% from 2024
  8. Manufactured Product, Other$26.9M64%down 7% from 2024
  9. Onapgo$17.3M62%
Products and services by year
Products and services202320242025
Qelbree$140.2M$241.3M$304.7M
Gocovri$119.6M$130.8M$146.8M
Collaboration Revenue$0$0$53.0M
Apokyn$75.1M$73.9M$47.8M
Trokendi Xr$94.3M$63.2M$42.4M
Oxtellar X R$113.4M$99.5M$40.7M
Royalty, License And Other Revenue$33.6M$24.1M$39.4M
Manufactured Product, Other$31.3M$29.0M$26.9M
Onapgo$0$0$17.3M

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Cost of revenue10¢$74.6M
  • Research and development15¢$106.2M
  • Selling, general and admin68¢$485.6M
  • Other costs6¢$42.1M
  • Income tax1¢$10.5M

Out of $719.0M in revenue.6 The company lost money this year.

Where each dollar of operating cash went, fiscal 2025

  • Capital spending3¢$1.3M
  • Kept or used elsewhere97¢$46.0M

Out of $47.3M of cash from operations.6

Financial statements

Revenue7896$719.0M in 2025+83% since 2019
0$200.0M$400.0M$600.0M$800.0M2019: $392.8M$392.8M20192020: $520.4M$520.4M2020+32%2021: $579.8M$579.8M2021+11%2022: $667.2M$667.2M2022+15%2023: $607.5M$607.5M2023−9%2024: $661.8M$661.8M2024+9%2025: $719.0M$719.0M2025+9%
Operating income7896-$62.3M in 2025
-$100.0M0$100.0M$200.0M2019: $148.6M$148.6M20192020: $173.7M$173.7M2020+17%2021: $86.0M$86.0M2021−50%2022: $46.1M$46.1M2022−46%2023: -$5.3M-$5.3M20232024: $81.7M$81.7M20242025: -$62.3M-$62.3M2025
Net income7896-$38.5M in 2025
-$50.0M0$50.0M$100.0M$150.0M2019: $113.1M$113.1M20192020: $127.0M$127.0M2020+12%2021: $53.4M$53.4M2021−58%2022: $60.7M$60.7M2022+14%2023: $1.3M$1.3M2023−98%2024: $73.9M$73.9M2024+5513%2025: -$38.5M-$38.5M2025

Every line of the income statement as filed: the last 3 fiscal years, latest first.6

Period ending2025-12-312024-12-312023-12-31
Total revenues$719.0M$661.8M$607.5M
Cost of revenues$74.6M$77.9M$83.8M
Research and development$106.2M$108.8M$91.6M
Selling, general and administrative$485.6M$321.6M$336.4M
Amortization of intangible assets$89.5M$78.0M$82.4M
Intangible asset impairment charges$0$0$20.2M
Contingent consideration loss (gain)$25.4M-$6.1M-$1.5M
Total costs and expenses$781.2M$580.2M$612.8M
Operating earnings (loss)-$62.3M$81.7M-$5.3M
Interest and other income, net$13.3M$16.2M$10.5M
Interest expense$0$0-$2.4M
Total other income (expense), net$13.3M$16.2M$8.0M
Earnings (loss) before income taxes-$49.0M$97.9M$2.8M
Income tax expense (benefit)-$10.5M$24.0M$1.5M
Net earnings (loss)-$38.5M$73.9M$1.3M
Basic (in dollars per share)-$0.68$1.34$0.02
Diluted (in dollars per share)-$0.68$1.32$0.02
Basic (in shares)56.5M shares55.1M shares54.5M shares
Diluted (in shares)56.5M shares56.0M shares55.5M shares

Compare SUPERNUS PHARMACEUTICALS, INC. with another company

Corporate structure

SUPERNUS PHARMACEUTICALS, INC. sits at the top of its group. 9 entities, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.

Major holders of SUPERNUS PHARMACEUTICALS, INC.

  • MILLENNIUM MANAGEMENT LLC Filed SCHEDULE 13G/A on SUPERNUS PHARMACEUTICALS, INC., latest Aug 6, 2026 (3 filings since Feb 2, 2026)
  • VANGUARD CAPITAL MANAGEMENT LLC Filed SCHEDULE 13G on SUPERNUS PHARMACEUTICALS, INC., latest Apr 30, 2026
  • VANGUARD PORTFOLIO MANAGEMENT LLC Filed SCHEDULE 13G on SUPERNUS PHARMACEUTICALS, INC., latest Apr 29, 2026
  • VANGUARD GROUP INC Filed SCHEDULE 13G/A on SUPERNUS PHARMACEUTICALS, INC., latest Mar 27, 2026 (4 filings since Feb 10, 2022)
  • ARMISTICE CAPITAL, LLC Filed SCHEDULE 13G/A on SUPERNUS PHARMACEUTICALS, INC., latest Feb 17, 2026 (9 filings since Feb 15, 2022)
  • DIMENSIONAL FUND ADVISORS LP Filed SCHEDULE 13G/A on SUPERNUS PHARMACEUTICALS, INC., latest Jan 21, 2026 (2 filings since Oct 31, 2024)
  • BlackRock Filed SCHEDULE 13G/A on SUPERNUS PHARMACEUTICALS, INC., latest Apr 22, 2025 (5 filings since Jan 26, 2022)
  • Macquarie Group Filed SC 13G/A on SUPERNUS PHARMACEUTICALS, INC., latest Nov 1, 2024 (2 filings since Feb 14, 2024)
  • SUPERNUS PHARMACEUTICALS, INC. Rockville, Maryland, United States
    • Adamas Holdings, LLC Subsidiary · Delaware, United States
    • Adamas Operations, LLC Subsidiary · Delaware, United States
    • Adamas Pharmaceuticals, LLC Subsidiary · Delaware, United States
    • Biscayne Neurotherapeutics, Inc. Subsidiary · Delaware, United States
    • MDD US Enterprises, LLC Subsidiary · Delaware, United States
    • MDD US Operations, LLC Subsidiary · Delaware, United States
    • Sage Securities Corporation Subsidiary · Massachusetts, United States
    • Sage Therapeutics, LLC Subsidiary · Delaware, United States

Built from parent and subsidiary links from GLEIF, the Global Legal Entity Identifier Foundation (CC0); subsidiaries listed in Exhibit 21 of annual reports filed with the SEC; major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

What it owns

What SUPERNUS PHARMACEUTICALS, INC. reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.

Property and equipment

ItemLatestA year beforeChange
Property and equipment, before depreciation$28.8M6 Dec 31, 2025$29.4M6 Dec 31, 2024−2.0%
Accumulated depreciation$18.3M6 Dec 31, 2025$17.8M6 Dec 31, 2024+2.4%
Property and equipment, net$10.5M6 Dec 31, 2025$11.5M6 Dec 31, 2024−8.8%
Operating-lease assets (leased space)$26.7M6 Dec 31, 2025$24.5M6 Dec 31, 2024+9.1%

Investments

ItemLatestA year beforeChange
Cash and cash equivalents$128.4M6 Dec 31, 2025$69.3M6 Dec 31, 2024+85.3%

Intangibles and goodwill

ItemLatestA year beforeChange
Goodwill$124.9M6 Dec 31, 2025$117.0M6 Dec 31, 2024+6.7%
Intangible assets, net (excluding goodwill)$569.5M6 Dec 31, 2025$521.9M6 Dec 31, 2024+9.1%
Accumulated amortization$396.7M6 Dec 31, 2025$307.2M6 Dec 31, 2024+29.1%

Inventory

ItemLatestA year beforeChange
Inventory, total$112.5M6 Dec 31, 2025$54.3M6 Dec 31, 2024+107.2%
Work in process$29.4M6 Dec 31, 2025$26.7M6 Dec 31, 2024+10.1%
Finished goods$21.1M6 Dec 31, 2025$16.4M6 Dec 31, 2024+28.4%

Properties, in its own words

Our principal executive offices are located at 9715 and 9717 Key West Avenue, Rockville, Maryland, where we occupy approximately 136,016 square feet of laboratory and office space. The term of this lease commenced on February 1, 2019, and shall continue until April 30, 2034. We believe that these facilities are sufficient for our present and contemplated operations.

Item 2 of the 10-K filed Mar 2, 2026.5

Leadership

Who has led SUPERNUS PHARMACEUTICALS, INC., and when. Pick a name to see everywhere that person has worked.

Board members and other officers (19)

Subsidiaries and ownership

Subsidiaries (Exhibit 21)

The subsidiaries the company lists in Exhibit 21 of its annual report, as filed.

Former names

  • SUPERNUS PHARMACEUTICALS INCMar 6, 2006 to Jun 12, 20193

Timeline

  1. Oct 15, 20268-K Shareholder vote34
  2. Aug 3, 20268-K Entered a material agreement; Executive or director change; Other events35
  3. Aug 3, 20268-K Results of operations36
  4. Aug 3, 20268-K Other events37
  5. Aug 3, 20268-K Other events38
  6. Jul 22, 20268-K Results of operations39
  7. Jun 18, 20268-K Shareholder vote40
  8. May 20, 20268-K New debt or obligation41
  9. May 5, 20268-K Results of operations42
  10. Apr 22, 20268-K Results of operations43
  11. Apr 7, 20268-K Entered a material agreement; Completed an acquisition or sale44
  12. Feb 24, 20268-K Results of operations45
  13. Apr 30, 2012New chief executive Jack A. Khattar becomes CEO13
  14. Mar 30, 2005Founded SUPERNUS PHARMACEUTICALS, INC. is founded2

Calendar

Coming up

  1. Nov 3, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported $0.46 a share, on Nov 4, 2025.46

When it reported results

  1. Aug 3, 2026Reported quarterly or annual results36
  2. Jul 22, 2026Reported quarterly or annual results39
  3. May 5, 2026Reported quarterly or annual results42
  4. Apr 22, 2026Reported quarterly or annual results43
  5. Feb 24, 2026Reported quarterly or annual results45
  6. Feb 12, 2026Reported quarterly or annual results47
  7. Nov 4, 2025Reported quarterly or annual results48
  8. Oct 21, 2025Reported quarterly or annual results49

Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar

Filings

528 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 95 major events, 279 insider forms, 27 large holders, 107 other. The latest 20:

  1. Oct 15, 20268-K EDGAR
  2. Oct 6, 2026425 EDGAR
  3. Oct 6, 2026DEFA14A EDGAR
  4. Sep 11, 2026DEFM14A EDGAR
  5. Aug 14, 20264 EDGAR
  6. Aug 14, 20264 EDGAR
  7. Aug 14, 20264 EDGAR
  8. Aug 14, 20264 EDGAR
  9. Aug 14, 20264 EDGAR
  10. Aug 6, 2026SCHEDULE 13G/A EDGAR
  11. Aug 4, 2026425 EDGAR
  12. Aug 3, 202610-Q EDGAR
  13. Aug 3, 20268-K EDGAR
  14. Aug 3, 2026425 EDGAR
  15. Aug 3, 2026DEFA14A EDGAR
  16. Aug 3, 2026425 EDGAR
  17. Aug 3, 20268-K EDGAR
  18. Aug 3, 2026DEFA14A EDGAR
  19. Aug 3, 2026425 EDGAR
  20. Aug 3, 20268-K EDGAR

The 528 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

87 open-market trades by officers, directors and large owners since October 2021: 0 buys and 87 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Mar 18, 2026Bhatt Padmanabh P.Sr. VP of IP, CSOSale7,250$49.60$359.6KForm 4
Mar 17, 2026Bhatt Padmanabh P.Sr. VP of IP, CSOSale50,000$50.30$2.5MForm 4
Mar 16, 2026Bhatt Padmanabh P.Sr. VP of IP, CSOSale50,000$50.28$2.5MForm 4
Mar 13, 2026Khattar Jack A.President, CEOSale35,000$50.38$1.8MForm 4
Mar 12, 2026Hudson Frederick M.DirectorSale5,369$50.61$271.7KForm 4
Mar 10, 2026Horich William ToddSVP, Commercial OperationsSale4,439$55.00$244.1KForm 4
Mar 9, 2026Horich William ToddSVP, Commercial OperationsSale4,438$54.00$239.7KForm 4
Mar 9, 2026Mottola FrankSVP, Chief Tech. Ops. OfficerSale1,623$53.65$87.1KForm 4
Mar 6, 2026GEMAYEL GEORGESDirectorSale8,787$53.00$465.7KForm 4
Mar 5, 2026GEMAYEL GEORGESDirectorSale10,000$53.71$537.1KForm 4
Feb 19, 2026Sensenig BethanyDirectorSale4,475$51.01$228.3KForm 4
Dec 19, 2025Mottola FrankSVP, Chief Tech. Ops. OfficerSale20,000$50.41$1.0MForm 4
Dec 18, 2025Bhatt Padmanabh P.Sr. VP of IP, CSOSale710$44.44$31.6KForm 4
Oct 9, 2025Khattar Jack A.President, CEOSale59,900$50.57$3.0MForm 4
Oct 9, 2025NEWHALL CHARLES W IIIDirectorSale25,000$50.77$1.3MForm 4
Oct 2, 2025Khattar Jack A.President, CEOSale1,904$48.06$91.5KForm 4
Oct 1, 2025Khattar Jack A.President, CEOSale40,173$48.07$1.9MForm 4
Sep 30, 2025Khattar Jack A.President, CEOSale8,588$48.25$414.4KForm 4
Sep 29, 2025Khattar Jack A.President, CEOSale10,235$48.02$491.5KForm 4
Sep 23, 2025Khattar Jack A.President, CEOSale29,513$47.23$1.4MForm 4

All 87 trades can be filtered by person here when JavaScript is on.

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Executive pay

What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.

YearExecutiveAgeSalaryTotal pay
2025Jack A. KhattarChief Executive Officer, President & Secretary64$1.0M$15.5M58
2025Timothy C. DecSenior Vice President, Chief Financial Officer67$504.9K$1.9M58
2025Jonathan Rubin, MDSenior Vice President, Chief Medical Officer Research and Development64$485.1K$1.4M58
2025Padmanabh P. Bhatt, Ph.D.Senior Vice President, Intellectual Property, Chief Scientific Officer68$455.9K$1.4M58
2025Frank MottolaSenior Vice President, Chief Technical Operations Officer54$412.5K$1.4M58
2024Jack A. KhattarChief Executive Officer, President & Secretary64$5.2M$826.3K58
2024Timothy C. DecSenior Vice President, Chief Financial Officer67$485.5K$229.2K58
2024Jonathan Rubin, MDSenior Vice President, Chief Medical Officer Research and Development64$466.4K$192.5K58
2024Padmanabh P. Bhatt, Ph.D.Senior Vice President, Intellectual Property, Chief Scientific Officer68$440.5K$163.4K58
2024Frank MottolaSenior Vice President, Chief Technical Operations Officer54$377.4K$140.0K58
2023Jack A. KhattarChief Executive Officer, President & Secretary64$963.0K$13.3M58
2023Frank MottolaSenior Vice President, Chief Technical Operations Officer54$352.7K$1.8M58
2023Jonathan Rubin, MDSenior Vice President, Chief Medical Officer Research and Development64$440.0K$1.6M58
2023Padmanabh P. Bhatt, Ph.D.Senior Vice President, Intellectual Property, Chief Scientific Officer68$427.7K$1.5M58
2023Timothy C. DecSenior Vice President, Chief Financial Officer67$453.8K$39.6K58

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
BlackRock, Inc.9,350,046$434.9M0.0%+552,792
Millennium Management LLC3,853,212$179.2M0.1%+537,239
Vanguard Portfolio Management LLC3,305,429$153.7M0.0%+66,736
Armistice Capital, LLC2,646,201$123.1M3.4%+750,854
Vanguard Capital Management LLC2,516,721$117.1M0.0%+49,506
State Street Corp2,459,828$114.4M0.0%+171,701
Nomura Asset Management International Inc.2,378,329$110.6M0.2%+341,127
Dimensional Fund Advisors LP2,078,090$96.7M0.0%−228,940
Geode Capital Management, LLC1,570,088$73.0M0.0%−53,426
Stephens Investment Management Group LLC1,485,821$69.1M0.7%+134,490
Renaissance Technologies LLC1,478,180$68.8M0.1%−227,042
Loomis Sayles & Co L P1,475,192$68.6M0.1%+49,413
Citadel Advisors LLC1,373,982$63.9M0.0%−119,464
Two Sigma Investments, LP1,184,378$55.1M0.0%+913,150
Sofinnova Investments, Inc.1,036,328$48.2M2.6%+82,019
Qube Research & Technologies Ltd922,166$42.9M0.0%+423,968
Morgan Stanley876,841$40.8M0.0%−37,052
Goldman Sachs Group Inc819,432$38.1M0.0%−37,055
D. E. Shaw & Co., Inc.767,668$35.7M0.0%+145,218
Northern Trust Corp733,374$34.1M0.0%+33,918
Woodline Partners LP708,276$32.9M0.1%+259,280
Charles Schwab Investment Management Inc703,552$32.7M0.0%−2,424
Bank Of America Corp /de/621,102$28.9M0.0%−93,124
Ashford Capital Management Inc613,783$28.5M3.1%−31,598
Soleus Capital Management, L.P.520,000$24.2M0.8%New

13F reports cover disclosed long positions in U.S. stocks only.

Members of Congress who traded it

9 trades disclosed by members of Congress. “Vs S&P since” is the stock’s change since the trade minus the S&P 500’s.

DateMemberTradeAmountVs S&P sinceFiling
Mar 3, 2026Gilbert Ray Cisneros, Jr.Democratic, HouseBuy$1,001 - $15,000−40.3%Report
Dec 11, 2025Gilbert Ray Cisneros, Jr.Democratic, HouseBuy$1,001 - $15,000−26.2%Report
Oct 9, 2025Gilbert Ray Cisneros, Jr.Democratic, HousePartial sale$1,001 - $15,000+34.4%Report
Mar 24, 2025Gilbert Ray Cisneros, Jr.Democratic, HouseBuy$1,001 - $15,000−12.4%Report
Dec 23, 2022Josh GottheimerDemocratic, HousePartial sale$1,001 - $15,000+95.0%Report
Nov 13, 2020Gilbert Ray Cisneros, Jr.Democratic, HouseBuy$1,001 - $15,000−42.1%Report
Jul 17, 2020Gilbert Ray Cisneros, Jr.Democratic, HouseBuy$1,001 - $15,000−75.0%Report
Jun 1, 2020Gilbert Ray Cisneros, Jr.Democratic, HouseBuy$1,001 - $15,000−85.3%Report
May 28, 2020Josh GottheimerDemocratic, HouseBuy$1,001 - $15,000−91.8%Report

Members report amounts as ranges, not exact figures. Returns are price-only (no dividends).

SEC filer profile

How SUPERNUS PHARMACEUTICALS, INC. is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.

  • Name on EDGARSUPERNUS PHARMACEUTICALS, INC.1
  • CIK0001356576
  • Employer ID (EIN)20-25901845
  • Filer statusLarge accelerated filer not an emerging growth company; not a smaller reporting company; not a shell company5
  • Incorporated inDelaware5
  • Fiscal year endsDecember 311
  • Industry code (SIC)2834 Pharmaceutical Preparations1
  • SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance1
  • Business address9715 Key West Avenue, Rockville, MD 208501
  • Phone301-838-25001
  • Shares outstanding58,127,013 as of Jul 28, 202611
  • Public float$1.7B as of Jun 30, 20255
  • AuditorKPMG LLP, Baltimore, Maryland PCAOB ID 185; it also attests to the company’s internal control over financial reporting5
  • On EDGAR sinceMar 6, 20061
  • Filings1,185 in all: 4 (495), 8-K (307), 144 (67), 10-Q (44), SC 13G/A (33), 3 (26), 4/A (15), SC 13D/A (15)1
    All 45 form types

    UPLOAD (15), 10-K (14), DEF 14A (14), DEFA14A (13), SC 13G (13), CORRESP (11), SCHEDULE 13G/A (10), S-1/A (9), ARS (7), CT ORDER (7), S-8 (7), 425 (6), 8-K/A (6), SC 13D (6), NT 10-K (4), NT 10-Q (4), SC TO-T/A (4), 10-Q/A (3), EFFECT (3), SC TO-C (3), SCHEDULE 13G (3), 424B4 (2), 5 (2), FWP (2), S-1 (2), SC TO-T (2), 10-K/A (1), 3/A (1), 8-A12B (1), CERTNAS (1), D (1), D/A (1), DEFM14A (1), PRE 14A (1), REGDEX/A (1), S-3 (1), S-8 POS (1)

  • Latest filingsAnnual report (10-K) Mar 2, 2026
    Quarterly report (10-Q) Aug 3, 2026
    Proxy statement (DEF 14A) Apr 30, 2026
    Latest 8-K (8-K) Oct 15, 2026

Securities registered for trading

ClassSymbolExchange
Common Stock, $0.001 Par ValueSUPNNASDAQ Stock Market LLC

From the cover page of the 10-K filed Mar 2, 2026 (Section 12(b) of the Exchange Act).5

Risk factors and legal proceedings

The risks SUPERNUS PHARMACEUTICALS, INC. names in Item 1A of its 10-K filed Mar 2, 2026: 57 risks under these headings, as written.5

  • Risks Related to Our Industry and Business
  • We are dependent on the commercial success of our products in the U.S.
  • If other versions of our products, including but not limited to generics containing one or more of the active pharmaceutical ingredients present in our products are approved and successfully commercialized, or if products are developed, approved and successfully commercialized which provide similar benefits of treatment for patients, our business could be materially harmed.
  • We are subject to uncertainty relating to payment or managed care reimbursement policies, which, if not favorable for our products or product candidates, could hinder or prevent our commercial success.
  • We depend on wholesalers, distributors, and specialty pharmacies for the distribution of our products. If we lose any of our significant wholesaler, distributor, or specialty pharmacy accounts, our business could be harmed.
  • We may not be able to effectively market and sell our product candidates, if approved, in the U.S.
  • Final marketing approval of any of our product candidates or approval of additional indications for existing products by the FDA or other regulatory authorities may be delayed, limited, or denied, any of which would adversely affect our ability to generate operating revenues.
  • If we do not obtain marketing exclusivity for our product candidates, our business may suffer.
  • If the FDA or other applicable regulatory authorities approve generic products that compete with any of our products or product candidates, the sales of our products or the commercial success of our product candidates would be adversely affected.
  • If our competitors develop or market alternatives for the treatment of our target indications, our commercial opportunities will be reduced or eliminated.
  • Our products and our product candidates may be subject to restrictions or withdrawal from the market. We may be subject to penalties if we fail to comply with regulatory requirements.
  • We depend on collaborators to work with us to develop, manufacture and commercialize their and our products and product candidates. We have in-licensed or acquired a portion of our intellectual property necessary to develop certain of our product candidates. If we fail to comply with our obligations under any of these arrangements, we could lose the benefit of such collaborative relationships, including licenses or intellectual property rights.
The other 46 risks
  • Even if our product candidates receive regulatory approval in the U.S., we or our collaborators may not receive approval to commercialize our product candidates outside of the U.S.
  • Our failure to successfully develop and market our product candidates would impair our ability to grow.
  • Recent Executive Orders May Impact our Financial Results.
  • We may be unable to acquire product candidates or products.
  • Our clinical trials for our product candidates may fail to demonstrate acceptable levels of safety, efficacy, or other requirements, which could prevent or significantly delay regulatory approval.
  • Delays or failures in the completion of clinical development of our product candidates would increase our costs, and delay, or limit our ability to generate revenues.
  • Our products and product candidates may cause undesirable side effects or have other characteristics that limit their commercial potential, delay, or prevent their regulatory approval.
  • We may not obtain or maintain the benefits associated with designation as an orphan drug under the Orphan Drug Act, including market exclusivity.
  • Healthcare reform measures could hinder or prevent the commercial success of our products or product candidates.
  • Healthcare cost containment legislation and the failure of third-party payors to provide appropriate levels of coverage and reimbursement for the use of products and treatments facilitated by our products could harm our business and prospects.
  • Any failure to comply with healthcare regulations, including implementation of any change in compliance with healthcare regulations and laws could cause us to incur significant compliance expenses and any failure to comply could subject us to substantial penalties and fines. Our business, operations, and financial condition could be adversely affected.
  • Guidelines and recommendations published by various organizations can reduce the use of our products and product candidates.
  • We could be involved in additional lawsuits to protect or enforce our patents, which could be expensive, time consuming, distracting, and ultimately unsuccessful.
  • Limitations on our patent rights relating to our products and product candidates may limit our ability to prevent third parties from competing with us.
  • If we are sued for infringing the intellectual property rights of third parties, it could be costly and time consuming to defend such a suit. An unfavorable outcome in such litigation could have a material adverse effect on our business.
  • We face potential litigation and product liability exposures. If successful claims are brought against us, we may incur substantial liabilities.
  • As we continue to increase the size of our organization, we may experience difficulties in managing growth.
  • Cybersecurity incidents may adversely impact our financial condition, results of operations, and reputation. Security breaches and other disruptions could compromise our information and expose us to liability which would cause our business and reputation to suffer.
  • We face significant competition in attracting and retaining talented employees. Further, managing succession for and retention of key executives is critical to our success. Our failure to do so could have an adverse impact on our future performance.
  • Our business involves the use of hazardous materials, and we must comply with environmental laws and regulations. This can be expensive and restrict how we do business.
  • Provisions in our agreement with Shire, or its successor, Takeda Pharmaceutical Company Limited, impose restrictive covenants on us, which could limit our ability to operate effectively in the future.
  • The Company’s financial condition and results of operations may be materially and adversely affected by health pandemics.
  • Ongoing legal actions and proceedings could distract management and could result in substantial costs or large judgments against Supernus or one or more of its subsidiaries.
  • Risks Related to Our Finances and Capital Requirements
  • Tariffs may increase our costs.
  • Our operating results may fluctuate significantly.
  • Our ability to use our net operating loss carryforwards and other tax attributes may be limited or may expire prior to utilization.
  • In the past, we have identified material weaknesses in our internal controls which might cause stockholders to lose confidence in our financial and other public reporting, particularly if not remediated appropriately and timely, which in turn would harm our business and the trading price of our common stock.
  • We have and may further expand our business through acquisitions of new product lines or businesses, which expose us to various risks, including difficulties in integrating acquisitions. Our recent acquisitions pose certain incremental risks to the Company.
  • Any impairment in the value of our intangible assets, including goodwill, could negatively affect our operating results and total capitalization.
  • Changes in tax laws or regulations that are applied adversely to us or our customers may have a material adverse effect on our business, cash flow, financial condition or results of operations.
  • Although we have historically been profitable from operations since the fourth quarter of 2014, there is no assurance that we will continue to generate net income in the future. We may not be able to maintain or increase profitability.
  • Risks Related to Securities Markets and Investment in Our Stock
  • The issuance of additional shares of our common stock, or instruments convertible into or rights to acquire shares or our common stock, or market sales of our common stock, could affect the market price of our common stock.
  • The price of our common stock may fluctuate substantially.
  • Anti-takeover provisions under our charter documents and Delaware law could delay or prevent a change of control, which could negatively impact the market price of our common stock.
  • To the extent outstanding stock options are exercised and restricted stock units and performance stock units vest there will be dilution to new investors.
  • Indebtedness and liabilities could limit the cash flow available for our operations, expose us to risks that could adversely affect our business, financial condition, and results of operations, and impair our ability to satisfy our obligations under the notes.
  • Our Credit Line is an uncommitted debt facility that may be terminated by the lender at any time.
  • General Risk Factors
  • Obtaining and maintaining patent protection depends on compliance with various procedural, document submission, fee payment, and other requirements imposed by governmental patent agencies. Our patent protection could be reduced or eliminated for non-compliance with these requirements.
  • Our insurance coverage may not be sufficient to cover our legal claims or other losses that we may incur in the future.
  • We may be subject to claims that our employees have wrongfully used or disclosed alleged trade secrets of their former employers.
  • We may enter into significant, complex, and unusual transactions, which may require us to engage outside consultants and financial professionals in order to comply with complex accounting and reporting requirements.
  • Our operations rely on sophisticated information technology, systems, and infrastructure, a disruption of which could harm our operations.
  • We may need additional funding and may be unable to raise capital when needed, which would force us to delay, reduce or eliminate our product development programs, commercialization, or business development efforts.
  • Complying with increased financial reporting and securities laws reporting requirements has increased our costs and requires additional management resources. We may fail to meet these obligations.
  • We have never paid dividends. Because we do not anticipate paying any cash dividends in the foreseeable future, capital appreciation, if any, of our common stock will be your sole source of gain on an investment in our common stock.
  • Unstable market and economic conditions may have serious adverse consequences on our business, financial condition and stock price.

Legal proceedings

From time to time and in the ordinary course of business, Supernus Pharmaceuticals, Inc. (Company) and any of its subsidiaries may be subject to various claims, charges and litigation. Parent and any of its subsidiaries may be required to file infringement claims against third parties for the infringement of our patents.

I. Supernus Pharmaceuticals, Inc. v. Ajanta Pharma Limited, et al., C.A. No. 21-cv-6964 (GC)(DEA) (D.N.J.)

The opening of Item 3, Legal Proceedings.5

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