TLPH on Nasdaq

AcelRx Pharmaceuticals (United States)

Logo: acelrx.com3

In its 2026 annual report the company says: “We are a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings. Our portfolio is principally focused on our lead product candidate, Niyad (nafamostat mesylate), for use as a regional anticoagulant during continuous renal replacement therapy, or CRRT.”5 It was founded in 2005.1 It is headquartered in Redwood City.1 Its shares trade on Nasdaq under the symbol TLPH.1

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Last updated Oct 21, 2026.

Overview

2005Founded1

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  • TickerTLPH on Nasdaq1
  • IndustryPharmaceutical Preparations1
  • HeadquartersRedwood City1
  • Websitewww.acelrx.com
  • Incorporated inDE4
  • Business address1850 Gateway Drive, Suite 175, San Mateo, Ca 944044
  • Filer categoryNon-accelerated filer, Smaller reporting company4
  • Legal formCorporation
AcelRx Pharmaceuticals (United States) image from its website
Image: acelrx.com3

We are a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings.5 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-48157.1%Operating margin6
-51035.7%Net margin6
-83.9%Return on equity6

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Research and development45¢$6.0M
  • Selling, general and admin55¢$7.5M

Out of $28.0K in revenue.6 The company lost money this year.

Financial statements

Revenue78910116$28.0K in 2025−99% since 2019
0$2.0M$4.0M$6.0M2019: $2.3M$2.3M20192020: $5.4M$5.4M2020+137%2021: $2.8M$2.8M2021−48%2022: $0$020222023: $651.0K$651.0K20232024: $0$020242025: $28.0K$28.0K2025
Operating income78910116-$13.5M in 2025−75% since 2019
-$60.0M-$40.0M-$20.0M02019: -$54.2M-$54.2M20192020: -$41.0M-$41.0M2020−24%2021: -$36.0M-$36.0M2021−12%2022: -$25.3M-$25.3M2022−30%2023: -$16.9M-$16.9M2023−33%2024: -$15.3M-$15.3M2024−10%2025: -$13.5M-$13.5M2025−12%
Net income78910116-$14.3M in 2025−73% since 2019
-$100.0M-$50.0M0$50.0M2019: -$53.2M-$53.2M20192020: -$40.4M-$40.4M2020−24%2021: -$35.1M-$35.1M2021−13%2022: $47.8M$47.8M20222023: -$18.4M-$18.4M20232024: -$13.0M-$13.0M2024−29%2025: -$14.3M-$14.3M2025+10%

Every line of the income statement as filed: the last 2 fiscal years, latest first.6

Period ending2025-12-312024-12-31
Revenue$28.0K$0
Research and development$6.0M$6.7M
Selling, general and administrative$7.5M$8.5M
Total operating costs and expenses$13.5M$15.3M
Loss from operations-$13.5M-$15.3M
Interest income and other income, net$436.0K$679.0K
Gain on sale of future payments$0$1.2M
(Loss) gain on change in fair value of warrant liability-$1.3M$717.0K
Non-cash interest expense on liability related to the sale of future payments$0-$394.0K
Total other income, net-$879.0K$2.2M
Net loss from continuing operations-$14.4M-$13.0M
Net income from discontinued operations See Note 3$73.0K$0
Net loss-$14.3M-$13.0M
Basic and diluted, continuing operations (in dollars per share)-$0-$0
Basic and diluted, discontinued operations (in dollars per share)$0$0
Basic and diluted loss per share (in dollars per share)-$0.34-$0.50
Shares used in computing net loss per share of common stock, basic and diluted See Note 10 (in shares)42.4M shares25.8M shares

Compare AcelRx Pharmaceuticals (United States) with another company

Corporate structure

AcelRx Pharmaceuticals (United States) sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.

Major holders of AcelRx Pharmaceuticals (United States)

  • Rosalind Advisors, Inc. Filed SCHEDULE 13G/A on AcelRx Pharmaceuticals (United States), latest Aug 12, 2026 (5 filings since Apr 11, 2025)
  • Laurence W. Lytton Filed SCHEDULE 13G/A on AcelRx Pharmaceuticals (United States), latest May 15, 2026 (3 filings since Sep 16, 2025)
  • Orin Hirschman Filed SCHEDULE 13G/A on AcelRx Pharmaceuticals (United States), latest Jan 30, 2026 (2 filings since Nov 10, 2025)
  • CorMedix Inc. Filed SCHEDULE 13D on AcelRx Pharmaceuticals (United States), latest Sep 12, 2025
  • Rock Springs Capital Management LP Filed SCHEDULE 13G on AcelRx Pharmaceuticals (United States), latest Sep 12, 2025
  • Nantahala Capital Management, LLC Filed SCHEDULE 13D/A on AcelRx Pharmaceuticals (United States), latest Apr 3, 2025 (3 filings since Jan 23, 2024)
  • ARMISTICE CAPITAL, LLC Filed SC 13G/A on AcelRx Pharmaceuticals (United States), latest Feb 14, 2024 (3 filings since Feb 15, 2022)
  • Lind Global Fund II LP Filed SC 13G/A on AcelRx Pharmaceuticals (United States), latest Feb 13, 2024 (2 filings since Aug 1, 2023)
  • BML Investment Partners, L.P. Filed SC 13G/A on AcelRx Pharmaceuticals (United States), latest Jan 27, 2022
  • AcelRx Pharmaceuticals (United States) Redwood City

Built from major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

What it owns

What AcelRx Pharmaceuticals (United States) reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.

Investments

ItemLatestA year beforeChange
Cash and cash equivalents$5.9M6 Dec 31, 2025$8.9M6 Dec 31, 2024−33.5%
Marketable securities, current$14.5M6 Dec 31, 2025$06 Dec 31, 2024

Intangibles and goodwill

ItemLatestA year beforeChange
Intangible assets, net (excluding goodwill)$8.8M6 Dec 31, 2025$8.8M6 Dec 31, 20240%

Properties, in its own words

We lease approximately 4,012 square feet of office space in San Mateo, California under a lease agreement that expires on August 31, 2027. We believe that our facilities are adequate to meet our current needs.

Item 2 of the 10-K filed Mar 23, 2026.5

Leadership

Who has led AcelRx Pharmaceuticals (United States), and when. Pick a name to see everywhere that person has worked.

Board members and other officers (21)

Named in SEC Form D filings

People the company listed in its private-offering notices.

  • Executive Officer, DirectorVincent J Angotti named Jan 24, 2022 to Sep 15, 202539
  • DirectorJill P Broadfoot named Jan 24, 2022 to Sep 15, 202539

Former names

  • ACELRX PHARMACEUTICALS INCFeb 19, 2008 to Dec 14, 20234

Timeline

  1. Aug 12, 20268-K Results of operations40
  2. Jun 23, 20268-K Executive or director change; Shareholder vote41
  3. May 13, 20268-K Results of operations42
  4. Mar 23, 20268-K Results of operations43
  5. Mar 16, 20268-K Unregistered sale of shares44
  6. Mar 13, 20268-K Listing notice or transfer45
  7. Nov 12, 20258-K Results of operations46
  8. Oct 24, 20258-K Executive or director change; Shareholder vote47
  9. Oct 22, 20258-K Unregistered sale of shares; Other events48
  10. Oct 16, 20258-K Executive or director change49
  11. Sep 10, 20258-K Entered a material agreement; Unregistered sale of shares50
  12. Aug 14, 20258-K Results of operations51
  13. Apr 3, 2015New chief executive Howard B. Rosen becomes CEO14
  14. 2005Founded Founded1

Calendar

Coming up

  1. Nov 11, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported ($0.11) a share, on Nov 12, 2025.52

When it reported results

  1. Aug 12, 2026Reported quarterly or annual results40
  2. May 13, 2026Reported quarterly or annual results42
  3. Mar 23, 2026Reported quarterly or annual results43
  4. Nov 12, 2025Reported quarterly or annual results46
  5. Aug 14, 2025Reported quarterly or annual results51
  6. May 14, 2025Reported quarterly or annual results53
  7. Mar 31, 2025Reported quarterly or annual results54
  8. Nov 13, 2024Reported quarterly or annual results55

Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar

Filings

306 filings to the SEC since October 2021: 8 annual reports, 15 quarterly reports, 67 major events, 115 insider forms, 21 large holders, 6 private raises, 74 other. The latest 20:

  1. Aug 12, 2026SCHEDULE 13G/A EDGAR
  2. Aug 12, 2026S-8 EDGAR
  3. Aug 12, 202610-Q EDGAR
  4. Aug 12, 20268-K EDGAR
  5. Jun 24, 20264 EDGAR
  6. Jun 24, 20264 EDGAR
  7. Jun 24, 20264 EDGAR
  8. Jun 24, 20264 EDGAR
  9. Jun 24, 20264 EDGAR
  10. Jun 24, 20264 EDGAR
  11. Jun 24, 20264 EDGAR
  12. Jun 23, 20268-K EDGAR
  13. May 21, 20264 EDGAR
  14. May 15, 2026SCHEDULE 13G/A EDGAR
  15. May 13, 202610-Q EDGAR
  16. May 13, 20268-K EDGAR
  17. May 12, 2026SCHEDULE 13G/A EDGAR
  18. Apr 29, 2026DEFA14A EDGAR
  19. Apr 29, 2026DEF 14A EDGAR
  20. Apr 3, 20264 EDGAR

The 306 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

20 open-market trades by officers, directors and large owners since October 2021: 17 buys and 3 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Mar 13, 2026Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy213,310$0.59$125.9KForm 4
Feb 12, 2026Aslam ShakilChief Medical OfficerBuy35,000$0.81$28.4KForm 4
Feb 12, 2026Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy105,364$0.81$85.3KForm 4
Feb 12, 2026ASADORIAN RAFFIChief Financial OfficerBuy45,000$0.81$36.5KForm 4
Feb 12, 2026Dasu Badri NChief Engineering OfficerBuy35,000$0.81$28.4KForm 4
Apr 2, 2025Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy213,310$0.59$125.9KForm 4
Dec 5, 2024Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy5,000$0.64$3.2KForm 4
Dec 2, 2024ASADORIAN RAFFIChief Financial OfficerSale155$0.77$119Form 4
Nov 27, 2024Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy5,000$0.73$3.6KForm 4
Aug 30, 2024Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy7,260$1.05$7.6KForm 4
Jun 14, 2024Aslam ShakilChief Medical OfficerBuy5,000$1.07$5.3KForm 4
Jun 14, 2024Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy1,304$1.08$1.4KForm 4
Jun 13, 2024Aslam ShakilChief Medical OfficerBuy695$0.98$681Form 4
Jun 13, 2024Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy4,570$0.97$4.4KForm 4
Jun 12, 2024Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy4,126$0.97$4.0KForm 4
Dec 13, 2023Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy10,000$0.73$7.3KForm 4
Sep 11, 2023Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy10,000$0.80$8.0KForm 4
Aug 25, 2023Palmer Pamela PChief Medical OfficerSale7,442$1.09$8.1KForm 4
Aug 24, 2023Palmer Pamela PChief Medical OfficerSale9,514$1.17$11.1KForm 4
Jun 7, 2022Angotti Vincent J.CHIEF EXECUTIVE OFFICERBuy46,400$0.22$10.2KForm 4

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Executive pay

What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.

YearExecutiveAgeSalaryTotal pay
2025Vincent J. Angotti58$688.8K$1.1M65
2025Raffi Asadorian56$520.9K$727.3K65
2025Shakil AslamM.D.61$473.2K$654.8K65
2024Chief Executive Officer$668.7K$1.0M65
2024Chief Financial Officer$505.8K$709.9K65
2024Chief Medical Officer$281.2K$529.2K65

Money raised

Private offerings the company reported to the SEC on Form D.

  1. Sep 10, 2025Raised $17 million in a private offering of equity Form D: $29 million offered in all Form D
  2. Apr 2, 2025Raised $4.9 million in a private offering of equity Form D: $15 million offered in all Form D
  3. Jan 22, 2024Raised $6 million in a private offering of securities Form D: 6 investors so far Form D
  4. Jul 17, 2023Raised $10 million in a private offering of equity Form D: 10 investors so far Form D
  5. Aug 3, 2022Raised $629,958 in a private offering of equity Form D: 1 investor so far Form D
  6. Jan 7, 2022Raised $5.2 million in a private offering of equity Form D: $6 million offered in all Form D

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 49. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Nantahala Capital Management, LLC6,985,038$7.2M0.2%+3,492,519
Rosalind Advisors, Inc.5,169,501$5.3M2.0%+1,815,585
AIGH Capital Management LLC4,601,502$4.7M0.4%−60,000
Rock Springs Capital Management LP3,589,186$3.7M0.2%No change
Cantor Fitzgerald, L. P.1,774,962$1.8M0.0%+887,481
Bleichroeder LP1,307,787$1.3M0.2%No change
Dauntless Investment Group, LLC746,051$768.4K1.3%+310,817
Vanguard Capital Management LLC701,877$722.9K0.0%+260,266
Caption Management, LLC514,969$530.4K0.0%−46,851
Almitas Capital LLC467,152$481.2K0.1%No change
Geode Capital Management, LLC429,062$442.0K0.0%+9,082
Shay Capital LLC405,764$417.9K0.0%+155,681
Vanguard Fiduciary Trust Co222,372$229.0K0.0%+29,967
Diadema Partners LP153,563$158.2K0.1%No change
UBS Group AG129,916$133.8K0.0%+116,092
Renaissance Technologies LLC113,300$116.7K0.0%−124,455
Mariner, LLC100,000$103.0K0.0%No change
BlackRock, Inc.91,548$94.3K0.0%No change
Northern Trust Corp88,296$90.9K0.0%No change
Values First Advisors, Inc.79,685$82.1K0.0%−1,832
Susquehanna International Group, Llp75,691$78.0K0.0%+25,075
Universal- Beteiligungs- und Servicegesellschaft mbH50,000$51.5K0.0%New
Persistent Asset Partners Ltd38,968$40.1K0.0%No change
Vanguard Global Advisers, LLC29,661$30.6K0.0%No change
Goldman Sachs Group Inc28,435$29.3K0.0%New

13F reports cover disclosed long positions in U.S. stocks only.

SEC filer profile

How AcelRx Pharmaceuticals (United States) is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.

  • Name on EDGARTALPHERA, INC.2
  • CIK0001427925
  • Employer ID (EIN)41-21936035
  • Filer statusNon-accelerated filer not an emerging growth company; a smaller reporting company; not a shell company5
  • Incorporated inDelaware5
  • Fiscal year endsDecember 312
  • Industry code (SIC)2834 Pharmaceutical Preparations2
  • SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance2
  • Business address1850 Gateway Drive, Suite 175, San Mateo, CA 944042
  • Phone650-216-35002
  • Shares outstanding51,905,796 as of Aug 6, 202613
  • Public float$8.3M as of Jun 30, 20255
  • AuditorBPM LLP, Walnut Creek, California PCAOB ID 207; no auditor attestation of internal control over financial reporting5
  • On EDGAR sinceFeb 19, 20082
  • Filings962 in all: 4 (368), 8-K (229), 10-Q (47), 3 (30), CORRESP (20), EFFECT (18), S-8 (17), 10-K (16)2
    All 44 form types

    424B5 (16), DEF 14A (16), UPLOAD (16), DEFA14A (15), SC 13G/A (15), S-3 (14), CT ORDER (12), 425 (11), SC 13G (11), D (10), 424B7 (9), SC 13D/A (8), SCHEDULE 13G/A (7), 10-K/A (6), S-1/A (6), 4/A (5), 8-K/A (4), PRE 14A (4), SC 13D (4), SCHEDULE 13G (4), 144 (3), 424B3 (2), 424B4 (2), ARS (2), S-1 (2), S-3/A (2), SCHEDULE 13D/A (2), 5 (1), 8-A12B (1), CERTNAS (1), POS AM (1), REGDEX (1), S-3MEF (1), S-4 (1), S-4/A (1), SCHEDULE 13D (1)

  • Latest filingsAnnual report (10-K) Mar 23, 2026
    Quarterly report (10-Q) Aug 12, 2026
    Proxy statement (DEF 14A) Apr 29, 2026
    Latest 8-K (8-K) Aug 12, 2026

Securities registered for trading

ClassSymbolExchange
Common Stock, $0.001 par valueTLPHNasdaq

From the cover page of the 10-K filed Mar 23, 2026 (Section 12(b) of the Exchange Act).5

Risk factors and legal proceedings

The risks AcelRx Pharmaceuticals (United States) names in Item 1A of its 10-K filed Mar 23, 2026: 47 risks under these headings, as written.5

  • Our operations and financial results are subject to various risks and uncertainties. You should carefully consider the risks described below, together with all of the other information in this report, including our financial statements and notes thereto. If any of the following risks actually materialize, our business, financial condition, results of operations, liquidity, and future prospects could be materially harmed, the price of our common stock could decline, and you could lose part or all of your investment.
  • Risks Related to Our Financial Condition and Need for Additional Capital
  • We have incurred significant losses since our inception and anticipate that we will continue to incur losses in the future.
  • We require additional capital and may be unable to raise such capital, which would force us to delay, reduce or eliminate our product development programs and commercialization efforts and could cause us to be unable to continue to operate as a going concern and cease operations.
  • To fund our operations and capital requirements, we may sell additional equity securities, which may result in dilution to our stockholders, or debt securities, or enter into a new debt facility which may impose restrictions on our business.
  • We have not yet generated significant product revenue and may never be profitable.
  • Risks Related to Drug Development and Commercialization
  • We may fail to realize the benefits expected from our acquisition of Lowell, which could adversely affect our stock price.
  • Delays in clinical trials are common and have many causes, and any delay could result in increased costs to us and jeopardize or delay our ability to obtain regulatory approval and commence product sales.
  • Our development efforts might not generate successful product candidates.
  • If clinical trials of our product candidates fail to demonstrate safety and efficacy to the satisfaction of regulatory authorities or do not otherwise produce positive results, we may incur additional costs or experience delays in completing, or ultimately be unable to complete, the development and commercialization of our product candidates.
  • If we experience delays or difficulties in enrolling patients in clinical trials, our receipt of necessary regulatory approvals could be delayed or prevented.
The other 37 risks
  • If serious adverse effects or unexpected characteristics of our product candidates are identified during development, we may need to abandon or limit the development of some or all of our product candidates.
  • We may expend our limited resources to pursue a particular product candidate or indication and fail to capitalize on product candidates or indications that may be more profitable or for which there is a greater likelihood of success.
  • The process for obtaining approval of a PMA or NDA is time consuming, subject to unanticipated delays and costs, and requires the commitment of substantial resources.
  • Our expectations for FDA approvability of our product candidates may be inaccurate, and we may be required to conduct additional manufacturing, nonclinical or clinical development work in order to obtain FDA approval for these products, which would add to our expenses and delay any associated revenue.
  • A key part of our business strategy is to establish collaborative relationships to commercialize and fund development and approval of our products, particularly outside of the United States. We may not succeed in establishing and maintaining collaborative relationships, which may significantly limit our ability to develop and commercialize our products successfully, if at all.
  • If we, or current and potential partners, are unable to compete effectively, our products may not reach their commercial potential.
  • Coverage and adequate reimbursement may not be available for our product candidates, if approved, in the United States and in Europe, which could make it difficult for us, or our partners, to sell our products profitably.
  • The FDA and other regulatory agencies actively enforce the laws and regulations prohibiting the promotion of off-label uses.
  • If we or our partners are unable to establish and maintain relationships with group purchasing organizations any future revenues or future profitability could be jeopardized.
  • Risks Related to Regulatory Approval of Our Product Candidates and Other Legal Compliance Matters
  • Existing and future legislation may increase the difficulty and cost for us to commercialize our products and affect the prices we may obtain.
  • Risks Related to Our Reliance on Third Parties
  • We will rely on third party manufacturers to produce clinical supplies of our product candidates. The failure of third-party manufacturers to provide us with adequate clinical supplies, and if approved, commercial supplies, could result in a material adverse effect on our business.
  • We rely on limited sources of supply for the active ingredient and finished product of our nafamostat-based product candidates and any disruption in the chain of supply may cause a delay in developing our product candidates.
  • Manufacturing issues may arise that could delay or increase costs related to product development and regulatory approval.
  • We rely on third parties to conduct, supervise and monitor our clinical trials, and if those third parties perform in an unsatisfactory manner, it may harm our business.
  • Risks Related to Our Business Operations and Industry
  • Our relationships with clinical investigators, health care professionals, consultants, commercial partners, third-party payers, hospitals, and other customers are subject to applicable anti-kickback, fraud and abuse and other healthcare laws, which could expose us to significant penalties.
  • Significant disruptions of our information technology systems or data security incidents could result in significant financial, legal, regulatory, business and reputational harm to us.
  • Business interruptions could delay our operations and sales efforts.
  • Our future success depends on our ability to retain key executives and to attract, retain and motivate qualified personnel.
  • We may acquire companies, product candidates or products or engage in strategic transactions, which could divert our management’s attention and cause us to incur various costs and expenses.
  • Our employees, independent contractors, principal investigators, consultants, commercial partners and vendors may engage in misconduct or other improper activities, including non-compliance with regulatory standards and requirements and insider trading.
  • Risks Related to Our Intellectual Property
  • If we cannot defend our issued patents from third party claims or if our pending patent applications fail to issue, our business could be adversely affected.
  • Litigation involving patents, patent applications and other proprietary rights is expensive and time consuming. If we are involved in such litigation, it could cause delays in bringing our products to market and interfere with our business.
  • It is difficult and costly to protect our proprietary rights, and we may not be able to ensure their protection.
  • We may be unable to adequately prevent disclosure of trade secrets and other proprietary information.
  • Periodic maintenance fees, renewal fees, annuity fees and various other governmental fees on patents and applications will be due to be paid to the United States Patent and Trademark Office and various foreign governmental patent agencies in several stages over the lifetime of the patents and/or applications.
  • We may not be able to enforce our intellectual property rights throughout the world.
  • We have not yet registered our trademarks in all our potential markets, and failure to secure those registrations could adversely affect our business.
  • Risks Related to Ownership of Our Common Stock
  • The market price of our common stock has historically been and may continue to be highly volatile.
  • Our common stock may be delisted from The Nasdaq Capital Market if we cannot regain compliance with Nasdaq’s continued listing requirements.
  • Sales of a substantial number of shares of our common stock in the public market by us or our stockholders could cause our stock price to fall.
  • We do not intend to pay dividends on our common stock so any returns will be limited to the value of our stock.
  • Provisions in our amended and restated certificate of incorporation and bylaws, as well as provisions of Delaware law, could make it more difficult for a third party to acquire us or increase the cost of acquiring us, even if doing so would benefit our stockholders or remove our current management.
  • Risks of a General Nature
  • Litigation may substantially increase our costs and harm our business.
  • International trade policies, including tariffs, sanctions and trade barriers may adversely affect our business, financial condition, results of operations and prospects.
  • Our ability to use our net operating loss carryforwards and certain other tax attributes may be limited.
  • Our effective tax rate may fluctuate, we may be adversely affected by changes in tax laws and regulations, and we may incur obligations in tax jurisdictions in excess of accrued amounts.

Legal proceedings

From time to time, we may be involved in legal proceedings relating to intellectual property, commercial, employment and other matters arising in the ordinary course of business. Such matters are subject to uncertainty and there can be no assurance that such legal proceedings will not have a material adverse effect on our business, results of operations, financial position or cash flows. Please see Note 7, “Commitments and Contingencies—Litigation” to our consolidated financial statements in this Annual Report on Form 10-K for additional information with respect to our legal proceedings.

The opening of Item 3, Legal Proceedings.5

Sources

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