TLPH on Nasdaq

AcelRx Pharmaceuticals (United States)
Logo: acelrx.com3
In its 2026 annual report the company says: “We are a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings. Our portfolio is principally focused on our lead product candidate, Niyad (nafamostat mesylate), for use as a regional anticoagulant during continuous renal replacement therapy, or CRRT.”5 It was founded in 2005.1 It is headquartered in Redwood City.1 Its shares trade on Nasdaq under the symbol TLPH.1
Price unavailable
Last updated Oct 21, 2026.
Overview
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- TickerTLPH on Nasdaq1
- IndustryPharmaceutical Preparations1
- HeadquartersRedwood City1
- Websitewww.acelrx.com
- Incorporated inDE4
- Business address1850 Gateway Drive, Suite 175, San Mateo, Ca 944044
- Filer categoryNon-accelerated filer, Smaller reporting company4
- Legal formCorporation
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We are a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings.5 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Key numbers, fiscal 2025
Where the money goes
Where each dollar of revenue went, fiscal 2025
- Research and development45¢$6.0M
- Selling, general and admin55¢$7.5M
Out of $28.0K in revenue.6 The company lost money this year.
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.6
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Revenue | $28.0K | $0 |
| Research and development | $6.0M | $6.7M |
| Selling, general and administrative | $7.5M | $8.5M |
| Total operating costs and expenses | $13.5M | $15.3M |
| Loss from operations | -$13.5M | -$15.3M |
| Interest income and other income, net | $436.0K | $679.0K |
| Gain on sale of future payments | $0 | $1.2M |
| (Loss) gain on change in fair value of warrant liability | -$1.3M | $717.0K |
| Non-cash interest expense on liability related to the sale of future payments | $0 | -$394.0K |
| Total other income, net | -$879.0K | $2.2M |
| Net loss from continuing operations | -$14.4M | -$13.0M |
| Net income from discontinued operations See Note 3 | $73.0K | $0 |
| Net loss | -$14.3M | -$13.0M |
| Basic and diluted, continuing operations (in dollars per share) | -$0 | -$0 |
| Basic and diluted, discontinued operations (in dollars per share) | $0 | $0 |
| Basic and diluted loss per share (in dollars per share) | -$0.34 | -$0.50 |
| Shares used in computing net loss per share of common stock, basic and diluted See Note 10 (in shares) | 42.4M shares | 25.8M shares |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 5 fiscal years (annual) or 5 quarters (quarterly), latest first.6
| Period ending | 2025-12-31 | 2025-08-31 | 2025-03-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|---|---|
| Cash and cash equivalents | $5.9M | $8.9M | |||
| Short-term investments | $14.5M | $0 | |||
| Prepaid expenses and other current assets | $519.0K | $554.0K | |||
| Total current assets | $20.9M | $9.4M | |||
| In-process research and development asset | $8.8M | $8.8M | |||
| Total assets | $29.7M | $18.2M | |||
| Accounts payable | $544.0K | $670.0K | |||
| Accrued and other liabilities | $2.6M | $1.3M | |||
| Liabilities of discontinued operations, current portion | $650.0K | $723.0K | |||
| Total current liabilities | $3.8M | $2.6M | |||
| Warrant liability | $2.4M | $1.1M | |||
| Liability related to the sale of future payments | $6.5M | $6.5M | $0 | ||
| Total liabilities | $12.7M | $10.2M | |||
| Common stock, $0.001 par value200,000,000 shares authorized as of December 31, 2025 and 2024; 49,328,097 and 17,029,469 shares issued and outstanding as of December 31, 2025 and 2024, respectively | $49.0K | $17.0K | |||
| Additional paid-in capital | $488.5M | $465.2M | |||
| Accumulated deficit | -$471.5M | -$457.2M | |||
| Total stockholders equity | $17.0M | $8.0M | $14.1M | ||
| Total Liabilities and Stockholders Equity | $29.7M | $18.2M | |||
| Common Stock, Par or Stated Value Per Share (in dollars per share) | $0.00 | $0.00 | $0.00 | $0.00 | |
| Common Stock, Shares Authorized (in shares) | 200.0M shares | 200.0M shares | |||
| Common Stock, Shares, Issued (in shares) | 49.3M shares | 17.0M shares | |||
| Common Stock, Shares, Outstanding (in shares) | 49.3M shares | 17.0M shares |
| Period ending | 2025-12-31 | 2025-08-31 | 2025-03-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|---|---|
| Cash and cash equivalents | $5.9M | $8.9M | |||
| Short-term investments | $14.5M | $0 | |||
| Prepaid expenses and other current assets | $519.0K | $554.0K | |||
| Total current assets | $20.9M | $9.4M | |||
| In-process research and development asset | $8.8M | $8.8M | |||
| Total assets | $29.7M | $18.2M | |||
| Accounts payable | $544.0K | $670.0K | |||
| Accrued and other liabilities | $2.6M | $1.3M | |||
| Liabilities of discontinued operations, current portion | $650.0K | $723.0K | |||
| Total current liabilities | $3.8M | $2.6M | |||
| Warrant liability | $2.4M | $1.1M | |||
| Liability related to the sale of future payments | $6.5M | $6.5M | $0 | ||
| Total liabilities | $12.7M | $10.2M | |||
| Common stock, $0.001 par value200,000,000 shares authorized as of December 31, 2025 and 2024; 49,328,097 and 17,029,469 shares issued and outstanding as of December 31, 2025 and 2024, respectively | $49.0K | $17.0K | |||
| Additional paid-in capital | $488.5M | $465.2M | |||
| Accumulated deficit | -$471.5M | -$457.2M | |||
| Total stockholders equity | $17.0M | $8.0M | $14.1M | ||
| Total Liabilities and Stockholders Equity | $29.7M | $18.2M | |||
| Common Stock, Par or Stated Value Per Share (in dollars per share) | $0.00 | $0.00 | $0.00 | $0.00 | |
| Common Stock, Shares Authorized (in shares) | 200.0M shares | 200.0M shares | |||
| Common Stock, Shares, Issued (in shares) | 49.3M shares | 17.0M shares | |||
| Common Stock, Shares, Outstanding (in shares) | 49.3M shares | 17.0M shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.6
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$14.3M | -$13.0M |
| Non-cash revenue related to sale of future payments | -$28.0K | $0 |
| Non-cash interest expense on liability related to sale of future payments | $0 | $394.0K |
| Net amortization of discount on short term investments | -$142.0K | -$121.0K |
| Stock-based compensation | $699.0K | $989.0K |
| Revaluation of warrant liability | $1.3M | -$717.0K |
| Prepaid expenses and other current assets | $35.0K | $1.6M |
| Accounts payable | -$208.0K | -$671.0K |
| Accrued liabilities | $1.3M | -$1.2M |
| Net cash used in operating activities | -$11.4M | -$12.7M |
| Purchase of investments | -$17.8M | -$5.0M |
| Proceeds from sale of investments | $10.0K | $0 |
| Proceeds from maturities of investments | $3.5M | $8.8M |
| Net cash (used in) provided by investing activities | -$14.3M | $3.8M |
| Gross proceeds from sale of future payments | $0 | $6.7M |
| Issuance costs related to sale of future payments | $0 | -$521.0K |
| Net proceeds from issuance of common stock through equity plans | $17.0K | $27.0K |
| Net cash provided by financing activities | $22.7M | $12.0M |
| Net change in cash and cash equivalents | -$3.0M | $3.1M |
| Equity issuance costs from warrant modification | $0 | $251.0K |
| Offering costs in accounts payable and accrued liabilities | $116.0K | $0 |
No quarter-by-quarter statement was filed.
Compare AcelRx Pharmaceuticals (United States) with another company
Corporate structure
AcelRx Pharmaceuticals (United States) sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.
Major holders of AcelRx Pharmaceuticals (United States)
- Rosalind Advisors, Inc. Filed SCHEDULE 13G/A on AcelRx Pharmaceuticals (United States), latest Aug 12, 2026 (5 filings since Apr 11, 2025)
- Laurence W. Lytton Filed SCHEDULE 13G/A on AcelRx Pharmaceuticals (United States), latest May 15, 2026 (3 filings since Sep 16, 2025)
- Orin Hirschman Filed SCHEDULE 13G/A on AcelRx Pharmaceuticals (United States), latest Jan 30, 2026 (2 filings since Nov 10, 2025)
- CorMedix Inc. Filed SCHEDULE 13D on AcelRx Pharmaceuticals (United States), latest Sep 12, 2025
- Rock Springs Capital Management LP Filed SCHEDULE 13G on AcelRx Pharmaceuticals (United States), latest Sep 12, 2025
- Nantahala Capital Management, LLC Filed SCHEDULE 13D/A on AcelRx Pharmaceuticals (United States), latest Apr 3, 2025 (3 filings since Jan 23, 2024)
- ARMISTICE CAPITAL, LLC Filed SC 13G/A on AcelRx Pharmaceuticals (United States), latest Feb 14, 2024 (3 filings since Feb 15, 2022)
- Lind Global Fund II LP Filed SC 13G/A on AcelRx Pharmaceuticals (United States), latest Feb 13, 2024 (2 filings since Aug 1, 2023)
- BML Investment Partners, L.P. Filed SC 13G/A on AcelRx Pharmaceuticals (United States), latest Jan 27, 2022
- AcelRx Pharmaceuticals (United States) Redwood City
Built from major holders from Schedules 13D and 13G. Each entity in the chart links to its source.
What it owns
What AcelRx Pharmaceuticals (United States) reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.
Investments
| Item | Latest | A year before | Change |
|---|---|---|---|
| Cash and cash equivalents | $5.9M6 Dec 31, 2025 | $8.9M6 Dec 31, 2024 | −33.5% |
| Marketable securities, current | $14.5M6 Dec 31, 2025 | $06 Dec 31, 2024 |
Intangibles and goodwill
| Item | Latest | A year before | Change |
|---|---|---|---|
| Intangible assets, net (excluding goodwill) | $8.8M6 Dec 31, 2025 | $8.8M6 Dec 31, 2024 | 0% |
Properties, in its own words
We lease approximately 4,012 square feet of office space in San Mateo, California under a lease agreement that expires on August 31, 2027. We believe that our facilities are adequate to meet our current needs.
Item 2 of the 10-K filed Mar 23, 2026.5
Leadership
Who has led AcelRx Pharmaceuticals (United States), and when. Pick a name to see everywhere that person has worked.
Chief executive
Chief financial officer
- Chief executive officerHoward B. Rosen Apr 3, 2015 to Feb 17, 201714
- Chief financial officerRaffi Asadorian Aug 17, 2017 to now15
- Chief financial officerTimothy E. Morris Apr 9, 2014 to Feb 9, 201716
- Chief financial officerJames H. Welch Feb 10, 2011 to Feb 6, 201417
Board members and other officers (21)
- Chief Medical OfficerShakil Aslam Oct 10, 2024 to now18
- Chief Commercial OfficerDavid Chung Sep 16, 2013 to Feb 6, 201419
- Chief Engineering OfficerBadri N. Dasu Feb 10, 2011 to now20
- Chief Development OfficerLawrence G. Hamel Feb 10, 2011 to Feb 13, 202021
- Chief Medical OfficerPamela P. Palmer Mar 4, 2011 to Mar 4, 202422
- Board memberJoseph Todisco Oct 16, 2025 to now23
- Board memberAbhinav Jain Jan 23, 2024 to now24
- Board memberMarina Bozilenko Mar 31, 2021 to now25
- Board memberJill Marie Church Nov 23, 2021 to now26
- Board memberC. Steven Hoffman Jul 28, 2014 to Jun 14, 201827
- Board memberAdrian Adams Feb 13, 2013 to now28
- Board memberRichard Afable Dec 12, 2013 to Dec 13, 202329
- Board memberGuy P. Nohra Feb 10, 2011 to Sep 23, 201330
- Board memberHoward B. Rosen Feb 10, 2011 to Dec 13, 202331
- Board memberMark A. Wan Feb 10, 2011 to now32
- Board memberPamela P. Palmer Feb 10, 2011 to Feb 27, 202433
- Board memberStephen J. Hoffman Feb 10, 2011 to now34
- Board memberThomas A. Schreck Feb 10, 2011 to Jul 26, 201235
- Board memberMark G. Edwards Sep 28, 2011 to Jun 17, 202136
- General counselJohn G. Saia Apr 18, 2018 to Apr 18, 201837
- General counselJane Wright Mitchell Jul 23, 2014 to Feb 9, 201738
Named in SEC Form D filings
People the company listed in its private-offering notices.
Former names
- ACELRX PHARMACEUTICALS INCFeb 19, 2008 to Dec 14, 20234
Timeline
- Aug 12, 20268-K Results of operations40
- Jun 23, 20268-K Executive or director change; Shareholder vote41
- May 13, 20268-K Results of operations42
- Mar 23, 20268-K Results of operations43
- Mar 16, 20268-K Unregistered sale of shares44
- Mar 13, 20268-K Listing notice or transfer45
- Nov 12, 20258-K Results of operations46
- Oct 24, 20258-K Executive or director change; Shareholder vote47
- Oct 22, 20258-K Unregistered sale of shares; Other events48
- Oct 16, 20258-K Executive or director change49
- Sep 10, 20258-K Entered a material agreement; Unregistered sale of shares50
- Aug 14, 20258-K Results of operations51
- Apr 3, 2015New chief executive Howard B. Rosen becomes CEO14
- 2005Founded Founded1
Calendar
Coming up
- Nov 11, 2026Reports results for the quarter ending Sep/2026 A year earlier it reported ($0.11) a share, on Nov 12, 2025.52
When it reported results
- Aug 12, 2026Reported quarterly or annual results40
- May 13, 2026Reported quarterly or annual results42
- Mar 23, 2026Reported quarterly or annual results43
- Nov 12, 2025Reported quarterly or annual results46
- Aug 14, 2025Reported quarterly or annual results51
- May 14, 2025Reported quarterly or annual results53
- Mar 31, 2025Reported quarterly or annual results54
- Nov 13, 2024Reported quarterly or annual results55
Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar
Filings
306 filings to the SEC since October 2021: 8 annual reports, 15 quarterly reports, 67 major events, 115 insider forms, 21 large holders, 6 private raises, 74 other. The latest 20:
- Aug 12, 2026SCHEDULE 13G/A EDGAR
- Aug 12, 2026S-8 EDGAR
- Aug 12, 202610-Q EDGAR
- Aug 12, 20268-K EDGAR
- Jun 24, 20264 EDGAR
- Jun 24, 20264 EDGAR
- Jun 24, 20264 EDGAR
- Jun 24, 20264 EDGAR
- Jun 24, 20264 EDGAR
- Jun 24, 20264 EDGAR
- Jun 24, 20264 EDGAR
- Jun 23, 20268-K EDGAR
- May 21, 20264 EDGAR
- May 15, 2026SCHEDULE 13G/A EDGAR
- May 13, 202610-Q EDGAR
- May 13, 20268-K EDGAR
- May 12, 2026SCHEDULE 13G/A EDGAR
- Apr 29, 2026DEFA14A EDGAR
- Apr 29, 2026DEF 14A EDGAR
- Apr 3, 20264 EDGAR
The 306 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
20 open-market trades by officers, directors and large owners since October 2021: 17 buys and 3 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Mar 13, 2026 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 213,310 | $0.59 | $125.9K | Form 4 |
| Feb 12, 2026 | Aslam ShakilChief Medical Officer | Buy | 35,000 | $0.81 | $28.4K | Form 4 |
| Feb 12, 2026 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 105,364 | $0.81 | $85.3K | Form 4 |
| Feb 12, 2026 | ASADORIAN RAFFIChief Financial Officer | Buy | 45,000 | $0.81 | $36.5K | Form 4 |
| Feb 12, 2026 | Dasu Badri NChief Engineering Officer | Buy | 35,000 | $0.81 | $28.4K | Form 4 |
| Apr 2, 2025 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 213,310 | $0.59 | $125.9K | Form 4 |
| Dec 5, 2024 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 5,000 | $0.64 | $3.2K | Form 4 |
| Dec 2, 2024 | ASADORIAN RAFFIChief Financial Officer | Sale | 155 | $0.77 | $119 | Form 4 |
| Nov 27, 2024 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 5,000 | $0.73 | $3.6K | Form 4 |
| Aug 30, 2024 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 7,260 | $1.05 | $7.6K | Form 4 |
| Jun 14, 2024 | Aslam ShakilChief Medical Officer | Buy | 5,000 | $1.07 | $5.3K | Form 4 |
| Jun 14, 2024 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 1,304 | $1.08 | $1.4K | Form 4 |
| Jun 13, 2024 | Aslam ShakilChief Medical Officer | Buy | 695 | $0.98 | $681 | Form 4 |
| Jun 13, 2024 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 4,570 | $0.97 | $4.4K | Form 4 |
| Jun 12, 2024 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 4,126 | $0.97 | $4.0K | Form 4 |
| Dec 13, 2023 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 10,000 | $0.73 | $7.3K | Form 4 |
| Sep 11, 2023 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 10,000 | $0.80 | $8.0K | Form 4 |
| Aug 25, 2023 | Palmer Pamela PChief Medical Officer | Sale | 7,442 | $1.09 | $8.1K | Form 4 |
| Aug 24, 2023 | Palmer Pamela PChief Medical Officer | Sale | 9,514 | $1.17 | $11.1K | Form 4 |
| Jun 7, 2022 | Angotti Vincent J.CHIEF EXECUTIVE OFFICER | Buy | 46,400 | $0.22 | $10.2K | Form 4 |
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- Rosalind Advisors, Inc.SCHEDULE 13G/A, 5 filings Apr 11, 2025 to Aug 12, 202656
- Laurence W. LyttonSCHEDULE 13G/A, 3 filings Sep 16, 2025 to May 15, 202657
- Orin HirschmanSCHEDULE 13G/A, 2 filings Nov 10, 2025 to Jan 30, 202658
- CorMedix Inc.SCHEDULE 13D, 1 filing Sep 12, 202559
- Rock Springs Capital Management LPSCHEDULE 13G, 1 filing Sep 12, 202560
- Nantahala Capital Management, LLCSCHEDULE 13D/A, 3 filings Jan 23, 2024 to Apr 3, 202561
- ARMISTICE CAPITAL, LLCSC 13G/A, 3 filings Feb 15, 2022 to Feb 14, 202462
- Lind Global Fund II LPSC 13G/A, 2 filings Aug 1, 2023 to Feb 13, 202463
- BML Investment Partners, L.P.SC 13G/A, 1 filing Jan 27, 202264
Executive pay
What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.
| Year | Executive | Age | Salary | Total pay |
|---|---|---|---|---|
| 2025 | Vincent J. Angotti | 58 | $688.8K | $1.1M65 |
| 2025 | Raffi Asadorian | 56 | $520.9K | $727.3K65 |
| 2025 | Shakil AslamM.D. | 61 | $473.2K | $654.8K65 |
| 2024 | Chief Executive Officer | $668.7K | $1.0M65 | |
| 2024 | Chief Financial Officer | $505.8K | $709.9K65 | |
| 2024 | Chief Medical Officer | $281.2K | $529.2K65 |
Money raised
Private offerings the company reported to the SEC on Form D.
- Sep 10, 2025Raised $17 million in a private offering of equity Form D: $29 million offered in all Form D
- Apr 2, 2025Raised $4.9 million in a private offering of equity Form D: $15 million offered in all Form D
- Jan 22, 2024Raised $6 million in a private offering of securities Form D: 6 investors so far Form D
- Jul 17, 2023Raised $10 million in a private offering of equity Form D: 10 investors so far Form D
- Aug 3, 2022Raised $629,958 in a private offering of equity Form D: 1 investor so far Form D
- Jan 7, 2022Raised $5.2 million in a private offering of equity Form D: $6 million offered in all Form D
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 49. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| Nantahala Capital Management, LLC | 6,985,038 | $7.2M | 0.2% | +3,492,519 |
| Rosalind Advisors, Inc. | 5,169,501 | $5.3M | 2.0% | +1,815,585 |
| AIGH Capital Management LLC | 4,601,502 | $4.7M | 0.4% | −60,000 |
| Rock Springs Capital Management LP | 3,589,186 | $3.7M | 0.2% | No change |
| Cantor Fitzgerald, L. P. | 1,774,962 | $1.8M | 0.0% | +887,481 |
| Bleichroeder LP | 1,307,787 | $1.3M | 0.2% | No change |
| Dauntless Investment Group, LLC | 746,051 | $768.4K | 1.3% | +310,817 |
| Vanguard Capital Management LLC | 701,877 | $722.9K | 0.0% | +260,266 |
| Caption Management, LLC | 514,969 | $530.4K | 0.0% | −46,851 |
| Almitas Capital LLC | 467,152 | $481.2K | 0.1% | No change |
| Geode Capital Management, LLC | 429,062 | $442.0K | 0.0% | +9,082 |
| Shay Capital LLC | 405,764 | $417.9K | 0.0% | +155,681 |
| Vanguard Fiduciary Trust Co | 222,372 | $229.0K | 0.0% | +29,967 |
| Diadema Partners LP | 153,563 | $158.2K | 0.1% | No change |
| UBS Group AG | 129,916 | $133.8K | 0.0% | +116,092 |
| Renaissance Technologies LLC | 113,300 | $116.7K | 0.0% | −124,455 |
| Mariner, LLC | 100,000 | $103.0K | 0.0% | No change |
| BlackRock, Inc. | 91,548 | $94.3K | 0.0% | No change |
| Northern Trust Corp | 88,296 | $90.9K | 0.0% | No change |
| Values First Advisors, Inc. | 79,685 | $82.1K | 0.0% | −1,832 |
| Susquehanna International Group, Llp | 75,691 | $78.0K | 0.0% | +25,075 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 50,000 | $51.5K | 0.0% | New |
| Persistent Asset Partners Ltd | 38,968 | $40.1K | 0.0% | No change |
| Vanguard Global Advisers, LLC | 29,661 | $30.6K | 0.0% | No change |
| Goldman Sachs Group Inc | 28,435 | $29.3K | 0.0% | New |
13F reports cover disclosed long positions in U.S. stocks only.
SEC filer profile
How AcelRx Pharmaceuticals (United States) is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.
- Name on EDGARTALPHERA, INC.2
- CIK0001427925
- Employer ID (EIN)41-21936035
- Filer statusNon-accelerated filer not an emerging growth company; a smaller reporting company; not a shell company5
- Incorporated inDelaware5
- Fiscal year endsDecember 312
- Industry code (SIC)2834 Pharmaceutical Preparations2
- SEC reviewing officeOffice of Life Sciences, Division of Corporation Finance2
- Business address1850 Gateway Drive, Suite 175, San Mateo, CA 944042
- Phone650-216-35002
- Shares outstanding51,905,796 as of Aug 6, 202613
- Public float$8.3M as of Jun 30, 20255
- AuditorBPM LLP, Walnut Creek, California PCAOB ID 207; no auditor attestation of internal control over financial reporting5
- On EDGAR sinceFeb 19, 20082
- Filings962 in all: 4 (368), 8-K (229), 10-Q (47), 3 (30), CORRESP (20), EFFECT (18), S-8 (17), 10-K (16)2
All 44 form types
424B5 (16), DEF 14A (16), UPLOAD (16), DEFA14A (15), SC 13G/A (15), S-3 (14), CT ORDER (12), 425 (11), SC 13G (11), D (10), 424B7 (9), SC 13D/A (8), SCHEDULE 13G/A (7), 10-K/A (6), S-1/A (6), 4/A (5), 8-K/A (4), PRE 14A (4), SC 13D (4), SCHEDULE 13G (4), 144 (3), 424B3 (2), 424B4 (2), ARS (2), S-1 (2), S-3/A (2), SCHEDULE 13D/A (2), 5 (1), 8-A12B (1), CERTNAS (1), POS AM (1), REGDEX (1), S-3MEF (1), S-4 (1), S-4/A (1), SCHEDULE 13D (1)
- Latest filingsAnnual report (10-K) Mar 23, 2026
Quarterly report (10-Q) Aug 12, 2026
Proxy statement (DEF 14A) Apr 29, 2026
Latest 8-K (8-K) Aug 12, 2026
Securities registered for trading
| Class | Symbol | Exchange |
|---|---|---|
| Common Stock, $0.001 par value | TLPH | Nasdaq |
From the cover page of the 10-K filed Mar 23, 2026 (Section 12(b) of the Exchange Act).5
Risk factors and legal proceedings
The risks AcelRx Pharmaceuticals (United States) names in Item 1A of its 10-K filed Mar 23, 2026: 47 risks under these headings, as written.5
- Our operations and financial results are subject to various risks and uncertainties. You should carefully consider the risks described below, together with all of the other information in this report, including our financial statements and notes thereto. If any of the following risks actually materialize, our business, financial condition, results of operations, liquidity, and future prospects could be materially harmed, the price of our common stock could decline, and you could lose part or all of your investment.
- Risks Related to Our Financial Condition and Need for Additional Capital
- We have incurred significant losses since our inception and anticipate that we will continue to incur losses in the future.
- We require additional capital and may be unable to raise such capital, which would force us to delay, reduce or eliminate our product development programs and commercialization efforts and could cause us to be unable to continue to operate as a going concern and cease operations.
- To fund our operations and capital requirements, we may sell additional equity securities, which may result in dilution to our stockholders, or debt securities, or enter into a new debt facility which may impose restrictions on our business.
- We have not yet generated significant product revenue and may never be profitable.
- Risks Related to Drug Development and Commercialization
- We may fail to realize the benefits expected from our acquisition of Lowell, which could adversely affect our stock price.
- Delays in clinical trials are common and have many causes, and any delay could result in increased costs to us and jeopardize or delay our ability to obtain regulatory approval and commence product sales.
- Our development efforts might not generate successful product candidates.
- If clinical trials of our product candidates fail to demonstrate safety and efficacy to the satisfaction of regulatory authorities or do not otherwise produce positive results, we may incur additional costs or experience delays in completing, or ultimately be unable to complete, the development and commercialization of our product candidates.
- If we experience delays or difficulties in enrolling patients in clinical trials, our receipt of necessary regulatory approvals could be delayed or prevented.
The other 37 risks
- If serious adverse effects or unexpected characteristics of our product candidates are identified during development, we may need to abandon or limit the development of some or all of our product candidates.
- We may expend our limited resources to pursue a particular product candidate or indication and fail to capitalize on product candidates or indications that may be more profitable or for which there is a greater likelihood of success.
- The process for obtaining approval of a PMA or NDA is time consuming, subject to unanticipated delays and costs, and requires the commitment of substantial resources.
- Our expectations for FDA approvability of our product candidates may be inaccurate, and we may be required to conduct additional manufacturing, nonclinical or clinical development work in order to obtain FDA approval for these products, which would add to our expenses and delay any associated revenue.
- A key part of our business strategy is to establish collaborative relationships to commercialize and fund development and approval of our products, particularly outside of the United States. We may not succeed in establishing and maintaining collaborative relationships, which may significantly limit our ability to develop and commercialize our products successfully, if at all.
- If we, or current and potential partners, are unable to compete effectively, our products may not reach their commercial potential.
- Coverage and adequate reimbursement may not be available for our product candidates, if approved, in the United States and in Europe, which could make it difficult for us, or our partners, to sell our products profitably.
- The FDA and other regulatory agencies actively enforce the laws and regulations prohibiting the promotion of off-label uses.
- If we or our partners are unable to establish and maintain relationships with group purchasing organizations any future revenues or future profitability could be jeopardized.
- Risks Related to Regulatory Approval of Our Product Candidates and Other Legal Compliance Matters
- Existing and future legislation may increase the difficulty and cost for us to commercialize our products and affect the prices we may obtain.
- Risks Related to Our Reliance on Third Parties
- We will rely on third party manufacturers to produce clinical supplies of our product candidates. The failure of third-party manufacturers to provide us with adequate clinical supplies, and if approved, commercial supplies, could result in a material adverse effect on our business.
- We rely on limited sources of supply for the active ingredient and finished product of our nafamostat-based product candidates and any disruption in the chain of supply may cause a delay in developing our product candidates.
- Manufacturing issues may arise that could delay or increase costs related to product development and regulatory approval.
- We rely on third parties to conduct, supervise and monitor our clinical trials, and if those third parties perform in an unsatisfactory manner, it may harm our business.
- Risks Related to Our Business Operations and Industry
- Our relationships with clinical investigators, health care professionals, consultants, commercial partners, third-party payers, hospitals, and other customers are subject to applicable anti-kickback, fraud and abuse and other healthcare laws, which could expose us to significant penalties.
- Significant disruptions of our information technology systems or data security incidents could result in significant financial, legal, regulatory, business and reputational harm to us.
- Business interruptions could delay our operations and sales efforts.
- Our future success depends on our ability to retain key executives and to attract, retain and motivate qualified personnel.
- We may acquire companies, product candidates or products or engage in strategic transactions, which could divert our management’s attention and cause us to incur various costs and expenses.
- Our employees, independent contractors, principal investigators, consultants, commercial partners and vendors may engage in misconduct or other improper activities, including non-compliance with regulatory standards and requirements and insider trading.
- Risks Related to Our Intellectual Property
- If we cannot defend our issued patents from third party claims or if our pending patent applications fail to issue, our business could be adversely affected.
- Litigation involving patents, patent applications and other proprietary rights is expensive and time consuming. If we are involved in such litigation, it could cause delays in bringing our products to market and interfere with our business.
- It is difficult and costly to protect our proprietary rights, and we may not be able to ensure their protection.
- We may be unable to adequately prevent disclosure of trade secrets and other proprietary information.
- Periodic maintenance fees, renewal fees, annuity fees and various other governmental fees on patents and applications will be due to be paid to the United States Patent and Trademark Office and various foreign governmental patent agencies in several stages over the lifetime of the patents and/or applications.
- We may not be able to enforce our intellectual property rights throughout the world.
- We have not yet registered our trademarks in all our potential markets, and failure to secure those registrations could adversely affect our business.
- Risks Related to Ownership of Our Common Stock
- The market price of our common stock has historically been and may continue to be highly volatile.
- Our common stock may be delisted from The Nasdaq Capital Market if we cannot regain compliance with Nasdaq’s continued listing requirements.
- Sales of a substantial number of shares of our common stock in the public market by us or our stockholders could cause our stock price to fall.
- We do not intend to pay dividends on our common stock so any returns will be limited to the value of our stock.
- Provisions in our amended and restated certificate of incorporation and bylaws, as well as provisions of Delaware law, could make it more difficult for a third party to acquire us or increase the cost of acquiring us, even if doing so would benefit our stockholders or remove our current management.
- Risks of a General Nature
- Litigation may substantially increase our costs and harm our business.
- International trade policies, including tariffs, sanctions and trade barriers may adversely affect our business, financial condition, results of operations and prospects.
- Our ability to use our net operating loss carryforwards and certain other tax attributes may be limited.
- Our effective tax rate may fluctuate, we may be adversely affected by changes in tax laws and regulations, and we may incur obligations in tax jurisdictions in excess of accrued amounts.
Legal proceedings
From time to time, we may be involved in legal proceedings relating to intellectual property, commercial, employment and other matters arising in the ordinary course of business. Such matters are subject to uncertainty and there can be no assurance that such legal proceedings will not have a material adverse effect on our business, results of operations, financial position or cash flows. Please see Note 7, “Commitments and Contingencies—Litigation” to our consolidated financial statements in this Annual Report on Form 10-K for additional information with respect to our legal proceedings.
The opening of Item 3, Legal Proceedings.5
Links
- Websitewww.acelrx.com1
- WikidataQ30270758
- SEC EDGARCIK 1427925
Sources
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- 3Company websiteAcelRx Pharmaceuticals (United States) logo
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- 18SEC EDGARShakil Aslam, Chief Medical Officer
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- 25SEC EDGARMarina Bozilenko, Board member
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- 27SEC EDGARC. Steven Hoffman, Board member
- 28SEC EDGARAdrian Adams, Board member
- 29SEC EDGARRichard Afable, Board member
- 30SEC EDGARGuy P. Nohra, Board member
- 31SEC EDGARHoward B. Rosen, Board member
- 32SEC EDGARMark A. Wan, Board member
- 33SEC EDGARPamela P. Palmer, Board member
- 34SEC EDGARStephen J. Hoffman, Board member
- 35SEC EDGARThomas A. Schreck, Board member
- 36SEC EDGARMark G. Edwards, Board member
- 37SEC EDGARJohn G. Saia, General counsel
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