Helen Hobbs

American medical researcher

Helen Haskell Hobbs (born May 5, 1952 in Boston, Massachusetts) is an American medical researcher who is professor at the University of Texas Southwestern Medical Center, and a Howard Hughes Medical Institute Investigator, who won a 2016 Breakthrough Prize in Life Sciences and the 2018 Harrington Prize for Innovation in Medicine. Hobbs specializes in the dysregulation of lipid metabolism and how it affects human diseases.²

From Wikipedia’s article on Helen Hobbs (this version), CC BY-SA 4.0.

Born May 5, 1952.¹

About

She and Jonathan C. Cohen found that people with hypomorphic PCSK9 mutations had lower LDL-cholesterol levels and were almost immune to heart disease. This finding led to the development of a new class of cholesterol-lowering drugs that mimic the effects of the PCSK9 mutations. She and Cohen also identified the first genetic risk factor for fatty liver disease, a burgeoning health problem that can lead to cirrhosis and liver cancer. Their laboratory has shown that mutation in PNPLA3 causes accumulation of PNPLA3 on lipid droplets, which compromises the mobilization of triglycerides from liver cells. She sits on the Board of Directors at Pfizer.

From Wikipedia’s article on Helen Hobbs, shared under CC BY-SA 4.0.²

Companies

PfizerBoard member 2011 to now¹⁹

Early life and education

Date not recordedStanford University³

Hobbs graduated from Stanford University and went to medical school at Case Western Reserve University School of Medicine. She completed an internship in internal medicine at Columbia-Presbyterian Medical Center, where she met her future husband, a Texan who trained at UT Southwestern. Together, Hobbs and her husband, Dr. Dennis Stone, moved to Dallas, Texas in 1980, where she completed her medical training at Parkland Memorial Hospital, including a one-year stint as chief resident.

Following the advice of Donald Seldin, the chairman of medicine at UT Southwestern Medical Center, she chose to pursue research after residency. Again, following Dr. Seldin's recommendation, Hobbs took a research post-doctoral position studying lipoproteins at UT Southwestern in the laboratory of Michael S. Brown and Joseph L. Goldstein, Nobel Prize in Medicine winners in 1985.

From Wikipedia’s article on Helen Hobbs (this version), CC BY-SA 4.0.

Career

Occupation: researcher, physician, university teacher, molecular geneticist, biochemist.^{8 9}

Since 2011Board member, Pfizer⁷
Since 2002Worked at Howard Hughes Medical Institute^{4 6}
Date not recordedWorked at University of Texas Southwestern Medical Center^{4 5}
Date not recordedWorked at University of Texas System⁴

Personal life

BornMay 5, 1952, Boston¹⁰
CitizenshipUnited States¹¹

Awards

2022Howard Taylor Ricketts Prize^{12 18}
2018George M. Kober Lectureship^{12 17}
2018Scientific Grand Prize of the Lefoulon-Delalande Fondation^{9 12}
2017Jay and Jeanie Schottenstein prize in cardiovascular science^{12 16}
2016Breakthrough Prize in Life Sciences^{12 15}
2015Fellow of the American Association for the Advancement of Science^{12 14}
2015Pearl Meister Greengard Prize¹²
2013Robert J. and Claire Pasarow Foundation Award for Distinguished Contributions to Cardiovascular Research^{12 13}
2005Heinrich Wieland Prize¹²
2003honorary doctor of the University of Ferrara¹²

Sources

The numbers on this page point here. Each one links to the record it came from.

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WikidataHelen Hobbs on Wikidata
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WikipediaHelen Hobbs on Wikipedia
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WikidataHelen Hobbs: education, on Wikidata
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WikidataHelen Hobbs: Worked at University of Texas Southwestern Medical Center, on Wikidata
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WikidataWorked at University of Texas Southwestern Medical Center, as reported
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WikidataWorked at Howard Hughes Medical Institute, as reported
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WikidataHelen Hobbs: Board member, Pfizer, on Wikidata
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WikidataHelen Hobbs: occupation, on Wikidata
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Wikidataoccupation, as reported
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WikidataHelen Hobbs: place of birth, on Wikidata
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WikidataHelen Hobbs: citizenship, on Wikidata
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WikidataHelen Hobbs: award, on Wikidata
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Wikidataaward, as reported
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Wikidataaward, as reported
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Wikidataaward, as reported
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Wikidataaward, as reported
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Wikidataaward, as reported
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Wikidataaward, as reported
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Wikidata and SEC EDGARPfizer, Board member