SPHERA FUNDS MANAGEMENT LTD.

Overview

• HeadquartersL3¹

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Corporate structure

SPHERA FUNDS MANAGEMENT LTD. sits at the top of its group. 11 entities, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.

Built from major holders from Schedules 13D and 13G; stakes of 5% or more it reported on Schedules 13D and 13G (10 companies); owners and owned firms from Form ADV, the registration investment advisers file with the SEC. Each entity in the chart links to its source.

Investment adviser

SPHERA FUNDS MANAGEMENT LTD. is registered with the SEC as an investment adviser. This is what it reports on Form ADV, the registration every adviser files and keeps current.

• RegistrationSEC 802-120694, CRD 312614 IAPD record

Who owns it

Owners of 5% or more as the firm lists them (Schedule A), and the owners of those owners up the chain (Schedule B).

• AVDINCO LTDowns 10% to 25%, since 03/2011
• KERENDOR LTD.owns 10% to 25%, since 01/2004
• MOR MITER (2004) LTDowns 10% to 25%, since 01/2004
• R.Y. SENATOR INVESTMENTS LTDowns 10% to 25%, since 01/2004
• Ehud Zvi Gelbardowns 5% to 10%, since 09/2009
• Eddy Shalevowns 5% to 10%, since 09/2009
• YAAD CONSULTING AND MANAGEMENT SERVICES (1995) LTDowns 5% to 10%, since 01/2004
• KERENDOR HOLDINGS (2004) LTDowns 75% or more of KERENDOR LTD., since 01/2004
• LENROK HOLDINGS LTDowns 75% or more of R.Y. SENATOR INVESTMENTS LTD LTD, since 01/2004
• MOR MITER HOLDINGS LTDowns 75% or more of MOR MITER (2004) LTD, since 01/2004
• Miriam Morowns 75% or more of MOR MITER HOLDINGS LTD, since 01/2004
• Yael Senatorowns 75% or more of LENROK HOLDINGS LTD, since 01/2004
• Itschak Shremowns 75% or more of YAAD CONSULTING AND MANAGEMENT SERVICES (1995) LTD, since 01/1995
• Ronnit Cohen Likvornikowns 25% to 50% of AVDINCO LTD, since 02/2018
• Daniella Cohen Salomiowns 25% to 50% of AVDINCO LTD, since 02/2018

Filings

24 filings to the SEC since October 2021: 24 other. The latest 20:

1. Aug 19, 2026N-PX EDGAR
2. Aug 14, 202613F-HR EDGAR
3. May 15, 202613F-HR EDGAR
4. Feb 17, 202613F-HR EDGAR
5. Nov 14, 202513F-HR EDGAR
6. Aug 28, 2025N-PX EDGAR
7. Aug 14, 202513F-HR EDGAR
8. May 15, 202513F-HR EDGAR
9. Feb 14, 202513F-HR EDGAR
10. Nov 14, 202413F-HR EDGAR
11. Aug 29, 2024N-PX EDGAR
12. Aug 14, 202413F-HR EDGAR
13. May 15, 202413F-HR EDGAR
14. Feb 15, 202413F-HR/A EDGAR
15. Feb 14, 202413F-HR EDGAR
16. Nov 14, 202313F-HR EDGAR
17. Aug 14, 202313F-HR EDGAR
18. May 15, 202313F-HR EDGAR
19. Feb 14, 202313F-HR EDGAR
20. Nov 14, 202213F-HR EDGAR

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Stakes it holds

SPHERA FUNDS MANAGEMENT LTD. has told the SEC it owns more than 5% of 10 companies, latest first (Schedules 13D and 13G).

• TENAX THERAPEUTICS, INC.SCHEDULE 13G/A Aug 27, 2026 to Oct 13, 2026³
• Outlook Therapeutics, Inc.SCHEDULE 13G/A Mar 3, 2025 to Feb 5, 2026⁴
• ProMIS Neurosciences Inc.SCHEDULE 13G/A Aug 30, 2023 to Feb 5, 2026⁵
• Chemomab Therapeutics Ltd.SCHEDULE 13G/A Aug 20, 2024 to Apr 10, 2025⁶
• Skye Bioscience, Inc.SCHEDULE 13G/A Feb 8, 2024 to Apr 10, 2025⁷
• Jasper Therapeutics, Inc.SC 13G/A Oct 10, 2023 to Nov 4, 2024⁸
• Inozyme Pharma, Inc.SC 13G/A Mar 7, 2023 to Feb 5, 2024⁹
• Praxis Precision Medicines, Inc.SC 13G/A Jun 22, 2023 to Feb 5, 2024¹⁰
• CyclacelSC 13G/A Feb 14, 2022 to Feb 6, 2023¹¹
• Altimmune, Inc.SC 13G/A Feb 14, 2022¹²