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Biotech calendar: December 2026

Industry-sponsored phase 2 and phase 3 trials with an estimated primary completion in December 2026, from ClinicalTrials.gov.

Trial readouts

555 trials: 196 phase 3 (including phase 2/3) and 359 phase 2. Phase 3 first, then by date. Click a column to sort; type to filter.

Primary completionSponsorDrugConditionPhaseStatusRecord
Dec 2026AbbVieABBV-RGX-314, Ranibizumab (LUCENTIS®)Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMDAMD, nAMD and 7 morePhase 2/3Active not recruitingNCT04704921
Dec 2026AbbVieLutikizumabA Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppu…Hidradenitis SuppurativaPhase 3Active not recruitingNCT06468228
Dec 2026AkesoAK112, Nab-paclitaxelAK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast CancerTriple-Negative Breast Cancer (TNBC)Phase 3RecruitingNCT06767527
Dec 2026Aldeyra Therapeutics, Inc.ICM ADX-2191 injection, Monthly ADX-2191 injectionA Clinical Trial Evaluating Patients With Primary Vitreoretinal LymphomaPrimary Vitreoretinal LymphomaPhase 3RecruitingNCT07402876
Dec 2026Allist Pharmaceuticals, Inc.Furmonertinib 80 mgTo Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage…Non-small Cell Lung CarcinomaPhase 3RecruitingNCT04853342
Dec 2026Astria Therapeutics, Inc.navenibartA Study of Navenibart in Participants With Hereditary AngioedemaHereditary Angioedema (HAE)Phase 3Active not recruitingNCT06842823
Dec 2026Atea Pharmaceuticals, Inc.Bemnifosbuvir-Ruzasvir, Sofosbuvir-VelpatasvirC-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCVHEPATITIS C VIRUS CHRONIC INFECTION, Hepatitis C, Chronic and 2 morePhase 3Active not recruitingNCT07037277
Dec 2026Axsome TherapeuticsSolriamfetol 150 mg, Solriamfetol 300 mgElucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using SolriamfetolBinge-Eating DisorderPhase 3RecruitingNCT06413433
Dec 2026Axsome TherapeuticsSolriamfetol 150 mg, Solriamfetol 300 mgStudying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)Excessive Sleepiness, Shift-work DisorderPhase 3RecruitingNCT06568367
Dec 2026Azidus Brasil–Efficacy and Safety of Nitazoxanide 600 Mg in the Outpatient Treatment of COVID-19 and InfluenzaCovid 19, InfluenzaPhase 3Not yet recruitingNCT06817096
Dec 2026Biohaven PharmaceuticalsBHV-7000A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset EpilepsyFocal EpilepsyPhase 2/3Active not recruitingNCT06132893
Dec 2026Boryung Pharmaceutical Co., LtdBR1019A, BR1019B, BR1019C and 3 moreA Study to Evaluate the Efficacy and Safety of BR1019A and BR1019B Combination TherapyEssential Hypertension, Type 2 Diabetes MellitusPhase 3RecruitingNCT06220773
Dec 2026CelltrionMetformin, Alogliptin, empagliflozinEfficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and MetforminT2DM, Diabete Type 2 and 1 morePhase 3RecruitingNCT07093476
Dec 2026Chengdu Kangnuoxing Biopharma,Inc.StapokibartStudy on the Treatment of Adolescent Patients With Seasonal Allergic RhinitisSeasonal Allergic Rhinitis (SAR)Phase 3RecruitingNCT07678931
Dec 2026Sino Biopharmaceutical LimitedAK105 Injection, Anlotinib Hydrochloride Capsules, Sorafenib Tosylate TabletsA Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepa…Advanced Hepatocellular Carcinoma (HCC)Phase 3Active not recruitingNCT04344158
Dec 2026Sino Biopharmaceutical LimitedTQB3454 tabletsA Clinical Study of TQB3454 Tablets in the Treatment of Advanced Biliary Carcinoma.Biliary CarcinomaPhase 3Active not recruitingNCT05987358
Dec 2026Sino Biopharmaceutical LimitedTQB3616 capsules, Letrozole, Anastrozole, TamoxifenClinical Study on Adjuvant Therapy of TQB3616 Combined With Endocrine Therapy Compared With Placebo Combined With Endocrine Therapy in Patie…Breast CancerPhase 3Active not recruitingNCT05780567
Dec 2026Cook MyoSiteIltamiocelIltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric InjuryFecal IncontinencePhase 3Active not recruitingNCT05776277
Dec 2026DiaMedica Therapeutics Inc.Recombinant human tissue kallikreinTreatment of Acute Ischemic Stroke (ReMEDy2 Trial)Acute Stroke, Ischemic Stroke and 1 morePhase 2/3RecruitingNCT05065216
Dec 2026Dr. Falk Pharma GmbHBudesonideOnce Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoEEosinophilic EsophagitisPhase 3Active not recruitingNCT06596252
Dec 2026Fujian Shengdi Pharmaceutical Co., Ltd.HRS9531A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of HRS9531 Injectio…Subjects With Moderate-to-severe OSA and Obesity Who Are on PAP TherapyPhase 3RecruitingNCT06994650
Dec 2026Fujian Shengdi Pharmaceutical Co., Ltd.HRS9531A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and ObesityBstructive Sleep Apnea (OSA) and ObesityPhase 3RecruitingNCT06974851
Dec 2026GC Cell CorporationImmuncell-LC, GemcitabineSafety and Efficacy of Immuncell-LC With Gemcitabine in Resectable Pancreatic CancerPancreatic Ductal AdenocarcinomaPhase 3RecruitingNCT04969731
Dec 2026Genelux Corporationolvimulogene nanivacirepvec, Platinum chemotherapy: carboplatin (preferred) or cisplatin, Non-platinum chemotherapy: Physician's Choice of gemcitabi… and 1 moreEfficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-…Platinum-resistant Ovarian Cancer, Platinum-refractory Ovarian Cancer and 5 morePhase 3RecruitingNCT05281471
Dec 2026Gilead SciencesSacituzumab Govitecan-hziy, Eribulin Mesylate Injection, Capecitabine Oral Product and 2 moreAsian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)Metastatic Breast CancerPhase 3Active not recruitingNCT04639986
Dec 2026Gossamer Bio, Inc.Seralutinib, Gereic Dry Powder InhalerOpen-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)Pulmonary Arterial HypertensionPhase 3RecruitingNCT06274801
Dec 2026Grand Shuyang Life Sciences (Chengdu) Co., Ltd.Human immunoglobulin (pH4) for intravenous injectionAn Open-label Study of Intravenous Immunoglobulin (5%) for the Treatment of Primary Immune ThrombocytopeniaPrimary Immune Thrombocytopenia (ITP)Phase 3RecruitingNCT07233213
Dec 2026Jiangsu Hengrui MedicineSHR-1819 InjectionA Clinical Study Evaluating the Efficacy and Safety of SHR-1819 Injection in Patients With Seasonal Allergic RhinitisSeasonal Allergic RhinitisPhase 3RecruitingNCT07688772
Dec 2026Harrow HealthSham (No Treatment), TRIESENCE (triamcinolone acetonide injectable suspension)A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain A…Postoperative Ocular Inflammation, Postoperative Ocular PainPhase 3Enrolling by invitationNCT07832552
Dec 2026Inmunotek S.L.10,000 MM09, 30,000 MM09Efficacy and Safety Evaluation for the Treatment of Allergy Against MitesRhinitis, Allergic, Rhinoconjunctivitis and 1 morePhase 3RecruitingNCT04435990
Dec 2026Intra-IMMUSG Pte LtdPRL3-ZUMABPhase II/III Trial of PRL3-Zumab in Advanced Solid Tumor PatientsAdvanced Solid CancersPhase 2/3RecruitingNCT07290088
Dec 2026Ionis Pharmaceuticals IncDonidalorsenA Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)Hereditary AngioedemaPhase 3Active not recruitingNCT05392114
Dec 2026Jiangsu Hengrui MedicineLutetium (177Lu) Oxodotreotide Injection；long-acting Octre…, long-acting OctreotideAn Open-label Phase 3 Study of Lutetium (177Lu) Oxodotreotide Injection in Subjects With Advanced Gastrointestinal Pancreatic Neuroendocrine…Advanced Gastroenteropancreatic Neuroendocrine TumorPhase 3RecruitingNCT05884255
Dec 2026Karyopharm Therapeutics Inc.Selinexor (combination therapy), Rituximab (combination therapy), Gemcitabine (combination therapy) and 3 moreA Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large…Relapsed/Refractory Diffuse Large B-cell LymphomaPhase 2/3Active not recruitingNCT04442022
Dec 2026Kedrion S.p.A.Kedrion IVIG 10%A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)Chronic Primary Immune Thrombocytopenia (ITP)Phase 3RecruitingNCT07059000
Dec 2026Kedrion S.p.A.Kedrion IVIG 10%Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in Pediatric PID Patients (KIDCARES10)Primary Immunodeficiency DiseasePhase 3Active not recruitingNCT04944979
Dec 2026Krystal Biotech, Inc.KB803A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis BullosaDystrophic Epidermolysis Bullosa, DEB - Dystrophic Epidermolysis Bullosa and 2 morePhase 3RecruitingNCT07016750
Dec 2026Mabscale, LLCBevacizumab, Paclitaxel, CarboplatinA Safety and Efficacy Study of Bevacizumab, Paclitaxel, Carboplatin Compared to Avastin® in Non-Small Cell Lung CancerNon-Small Cell Lung CancerPhase 3RecruitingNCT05654454
Dec 2026Madrigal Pharmaceuticals, INC.ResmetiromA Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUT…NASH, Cirrhosis, LiverPhase 3Active not recruitingNCT05500222
Dec 2026MediWound Ltd.EscharEx (EX-03)A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)Venous Leg Ulcer (VLU)Phase 3RecruitingNCT06568627
Dec 2026Minghui Pharmaceutical (Hangzhou) LtdMHB018AMHB018A Treatment in Patients With Active Thyroid Eye DiseaseThyroid Associated OphthalmopathiesPhase 3Active not recruitingNCT06989918
Dec 2026Nanjing Chia-tai Tianqing PharmaceuticalRamelteonA Study of Ramelteon in Chinese Patients With Chronic InsomniaChronic InsomniaPhase 3Not yet recruitingNCT06512363
Dec 2026Napo Pharmaceuticals, Inc.Crofelemer Powder for Oral SolutionAscending Doses of Crofelemer Powder for Oral Solution in Pediatric Microvillus Inclusion Disease (MVID)Microvillus Inclusion Disease, Congenital Disorders and 1 morePhase 2/3Active not recruitingNCT06721871
Dec 2026OctapharmaOCTA-C1-INHStudy of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-proce…Acute Hereditary Angio EdemaPhase 3RecruitingNCT06361537
Dec 2026OculisArtificial Tear Run-in, licaminlimabA Clinical Study Evaluating Licaminlimab for Dry Eye DiseaseDry Eye Disease (DED)Phase 2/3RecruitingNCT07548632
Dec 2026Otsuka PharmaceuticalOPA-15406A Phase 3 Trial to Demonstrate the Superiority of 1% OPA-15406 Foam to the Vehicle in Adult Patients With Atopic DermatitisAtopic Dermatitis (AD)Phase 3Not yet recruitingNCT07173478
Dec 2026Pacira Pharmaceuticals, Inc.ZILRETTAZILRETTA in Subjects With Shoulder OsteoarthritisGlenohumeral OsteoarthritisPhase 3Active not recruitingNCT06269705
Dec 2026Praxis Precision Medicines, Inc.1mg elsunersen, 0.5mg elsunersenA Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and SafetyEpileptic Encephalopathy, SCN2A EncephalopathyPhase 3RecruitingNCT07019922
Dec 2026Praxis Precision Medicines, Inc.1.0mg/kg/day PRAX-562, 1.5mg/kg/day PRAX-562A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of RelutrigineDevelopmental and Epileptic Encephalopathy 1Phase 3Active not recruitingNCT07010471
Dec 2026Prove pharmIndigotindisulfonate sodium 0.8% injectionIndigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Pediatric PatientsUreter InjuryPhase 3Not yet recruitingNCT06448143
Dec 2026Qilu Pharmaceutical Co., Ltd.Meropenem and Pralurbactam, Best Available Therapy (e.g., colistin, meropenem, tegecyc…Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in Carbapenem-Resistant Enterobacteriaceae InfectionsHospital-acquired Bacterial Pneumonia (HABP), Ventilator-associated Bacterial Pneumonia (VABP) and 3 morePhase 3RecruitingNCT07089186
Dec 2026Qilu Pharmaceutical Co., Ltd.QL2107, Pemetrexed, Carboplatin and 1 moreA Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLCNSCLCPhase 3RecruitingNCT06754644
Dec 2026Qilu Pharmaceutical Co., Ltd.QLG1091, RybelsusEfficacy and Safety of QLG1091 vs Rybelsus as add-on to Metformin in Subjects With Type 2 DiabetesType 2 DiabetesPhase 3Not yet recruitingNCT07487103
Dec 2026Qilu Pharmaceutical Co., Ltd.QL1207H injection, Aflibercept 8 mgA Clinical Study of QL1207H Injection Versus Aflibercept for Neovascular Age-related Macular DegenerationNeovascular Age-Related Macular Degeneration (nAMD)Phase 3Not yet recruitingNCT07489586
Dec 2026RayzeBio, Inc.RYZ101, Everolimus, Sunitinib and 2 moreStudy of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA TherapyGEP-NET, Gastroenteropancreatic Neuroendocrine Tumor and 5 morePhase 3Active not recruitingNCT05477576
Dec 2026RemeGen Co., Ltd.Disitamab Vedotin Injection, Cadonilimab Injection, Paclitaxel InjectionDV Combined With Cadonilimab in Subjects With HER2-expressing Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression …Gastric Cancer, Gastroesophageal Junction AdenocarcinomaPhase 2/3RecruitingNCT06221748
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, DocetaxelA Study Comparing BL-B01D1 With Docetaxel in Patients With Unresectable Locally Advanced or Metastatic EGFR Wild-type Non-small Cell Lung Ca…Non-small Cell Lung CancerPhase 3Active not recruitingNCT06382129
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, TopotecanA Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancer(PANKU-Lung03)Small Cell Lung CancerPhase 3Active not recruitingNCT06500026
Dec 2026Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.SKB264, Pembrolizumab, pemetrexed and 1 moreA Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 …Non-Small Cell Lung CancerPhase 3Active not recruitingNCT06711900
Dec 2026Sound Pharmaceuticals, IncorporatedEbselenSPI-1005 for the Treatment of Meniere's Disease (Open Label)Meniere's Disease, Ménière's DiseasePhase 3Active not recruitingNCT06859788
Dec 2026Suven Life Sciences LimitedMasupirdine 50 mg, Masupirdine 100 mgMasupirdine for the Treatment of Agitation in Dementia of the Alzheimer's TypeAgitation, Alzheimer's Type DementiaPhase 3Active not recruitingNCT05397639
Dec 2026Jiangsu Hengrui MedicineSHR-A2009 monotherapy, platinum-based dual-agent chemotherapyA Study of SHR-A2009 Versus Platinum-based Chemotherapy in EGFR-mutated, Advanced or Metastatic NSCLCNon-small Cell Lung CancerPhase 3Active not recruitingNCT06671379
Dec 2026TR Therapeutics–Tissue Repair Gel in Venous Leg Ulcers in AU/USVenous Leg Ulcer, Venous Ulcer and 6 morePhase 3RecruitingNCT06707103
Dec 2026Tasly Pharmaceuticals, Inc.T89 capsuleOutcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable AnginaChronic Stable Angina PectorisPhase 3RecruitingNCT03789552
Dec 2026TransThera Sciences (Nanjing), Inc.Tinengotinib 8 mg, Tinengotinib 10 mg, Physician's ChoiceStudy of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in CholangiocarcinomaCholangiocarcinomaPhase 3Active not recruitingNCT05948475
Dec 2026UNITED THERAPEUTICS CorpRalinepagA Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label ExtensionPAH, Pulmonary Hypertension and 9 morePhase 3Enrolling by invitationNCT03683186
Dec 2026VIS, Inc.Optimal laser keratoplastyPhase III Presbyopia Correction Using the VIS Opti-K™ SystemPresbyopiaPhase 3RecruitingNCT06487897
Dec 2026Vanda Pharmaceuticals Inc.VQW-765Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety DisorderSocial Anxiety Disorder (SAD)Phase 3Active not recruitingNCT07221578
Dec 2026Veradermics, IncVDPHL01Safety and Efficacy of VDPHL01 in Males With AGAAndrogenetic Alopecia, AGA and 1 morePhase 3Active not recruitingNCT06972264
Dec 2026Vergent Bioscience, Inc.Abenacianine, Near Infrared (NIR) ImagingEvaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the LungLung Cancer, Lung MetastasesPhase 3RecruitingNCT07499674
Dec 2026VIR BiotechnologyTobevibart, Elebsiran, BulevirtideA Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With BulevirtideViral HepatitisPhase 3Active not recruitingNCT07128550
Dec 2026Wuxi Cellular Biopharmaceutical Group Ltd.Mesenchymal Stem Cells, Sodium Hyaluronate InjectionAllogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Knee OsteoarthritisKnee OsteoarthritisPhase 3RecruitingNCT06570291
Dec 2026iCoat Medical ABiCM012 solution 2 mg/mLA Trial to Assess Efficacy and Safety of ex Vivo Allograft Admin of iCM012 Solution 2 mg/ml to Improve Its Function in Recipients of DCD Kid…Ischemia-reperfusion Injury, Kidney Transplant; ComplicationsPhase 2/3Not yet recruitingNCT06582485
Dec 1, 2026BiogenFelzartamabA Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rej…Antibody-mediated RejectionPhase 3Active not recruitingNCT06685757
Dec 1, 2026Fujian Akeylink Biotechnology Co., Ltd.GST-HG141To Evaluate the Efficacy, Safety and Population Pharmacokinetics of GST-HG141 in Patients With Chronic Hepatitis B (CHB) Who Have an Inadequ…Chronic Hepatitis bPhase 3RecruitingNCT07090759
Dec 1, 2026Guangdong Raynovent Biotech Co., LtdRAY1225, SemaglutideA Study of RAY1225 Versus Semaglutide as Add-on Therapy to Oral Antidiabetic Drugs in Participants With Type 2 DiabetesT2DMPhase 3Not yet recruitingNCT07139548
Dec 1, 2026Guangdong Raynovent Biotech Co., LtdRAY1225A Study of RAY1225 in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise AloneT2DMPhase 3Not yet recruitingNCT07139535
Dec 1, 2026HealthBio, Inc.Maraviroc (MVC), Atorvastatin, 10mg, 20mg, 40mgA Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the…Long COVIDPhase 2/3Not yet recruitingNCT06974084
Dec 1, 2026JYAMS PET Research & Development Limited[18F]-APN-1607Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive FunctionSubjects With Mild Cognitive Impairment (MCI) of AD, Alzheimer's Disease (AD) DementiaPhase 3RecruitingNCT07422857
Dec 1, 2026Johnson & JohnsonApalutamide, Androgen Deprivation Therapy (ADT)A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostate…Prostatic NeoplasmsPhase 3Active not recruitingNCT03767244
Dec 1, 2026Kind Pharmaceuticals LLCAND017, ESAA Study of AND017 to Evaluate Efficacy and Safety in Patients With Anemia Due to Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD)Anemia Due to Chronic Kidney DiseasePhase 3RecruitingNCT07487727
Dec 1, 2026OctapharmaAtenativEfficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or DeliveryCongenital Antithrombin DeficiencyPhase 3RecruitingNCT04918173
Dec 1, 2026SanofiPCV21, 20vPCVStudy of the Safety and Immunogenicity of Catch-up Vaccination With a 21-valent Pneumococcal Conjugate Vaccine (PCV21) in Healthy Infants, T…Pneumococcal InfectionsPhase 3Active not recruitingNCT06838000
Dec 1, 2026Shanghai PharmaceuticalsSPH4336 TabletsSafety and Efficacy of SPH4336 in Combination With Endocrine Therapy in the Treatment of Locally Advanced or Metastatic Breast CancerLocally Advanced or Metastatic Breast CancerPhase 2/3RecruitingNCT05860465
Dec 1, 2026Shanghai Vitalgen BioPharma Co., Ltd.VGR-R01Study to Evaluate the Efficacy and Safety of VGR-R01 Gene Therapy in Patients With Bietti Crystalline DystrophyBietti Crystalline Dystrophy, Inherited Retinal DiseasesPhase 3Active not recruitingNCT06699108
Dec 1, 2026Tasly Pharmaceutical Group Co., LtdJitongning tablets, a simulated agent of Jitongning tabletsA Study of Comparing Overall Improvement of Patients With Spondyloarthritis Treated With Jitongning Tablets and PlaceboAnkylosing SpondylitisPhase 3RecruitingNCT06000956
Dec 1, 2026Vanda Pharmaceuticals Inc.TradipitantA Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist UseNausea and Vomiting, ObesityPhase 3RecruitingNCT07446439
Dec 1, 2026Virchow GroupIVIG-VImmune, IVIG-ImmugloEfficacy, Safety and Pharmacokinetic of Virchow IVIG in PID PatientsPrimary Immunodeficiency Diseases (PID)Phase 3Not yet recruitingNCT07017036
Dec 2, 2026PfizerPF-06821497, EnzalutamideA Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.Metastatic Castration-Resistant Prostate CancerPhase 3RecruitingNCT06629779
Dec 2, 2026PfizerRitlecitinib higher dose, Ritlecitinib lower doseA Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia AreataSevere Alopecia AreataPhase 3Active not recruitingNCT07029711
Dec 4, 2026PfizerVLA15A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease VaccineLyme DiseasePhase 3RecruitingNCT07500506
Dec 7, 2026AstraZenecaeculizumabEfficacy, Safety, PK, PD, and ADA of Eculizumab in Chinese Adults With NMOSDNMOSD, Neuromyelitis Optica Spectrum DisordersPhase 3Active not recruitingNCT06724809
Dec 8, 2026Johnson & JohnsonMilvexian, ApixabanA Study of Milvexian Versus Apixaban in Participants With Atrial FibrillationAtrial FibrillationPhase 3Active not recruitingNCT05757869
Dec 9, 2026Bristol-Myers SquibbKarXTA Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)Psychosis Associated With Alzheimer's DiseasePhase 3RecruitingNCT06126224
Dec 10, 2026Boehringer Ingelheimzongertinib, pembrolizumab, cisplatin and 2 moreBeamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations C…Lung Cancer, Non-squamous, Non-small CellPhase 3Active not recruitingNCT06151574
Dec 11, 2026Gan & Lee Pharmaceuticals Co., Ltd.GZR18, semaglutideA Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes MellitusType 2 Diabetes Mellitus (T2DM)Phase 3Active not recruitingNCT06778967
Dec 12, 2026CSPC Pharmaceutical GroupSYS6010, Osimertinib, platinum-pemetrexedA Phase Ⅲ Clinical Study of SYS6010 in Combination With Osimertinib in Patients With Locally Advanced or Metastatic NSCLCNSCLCPhase 3Not yet recruitingNCT07376382
Dec 13, 2026Jiangsu Hengrui Medicine–To Evaluate the Efficacy and Safety of SHR0302 Tablet in Subjects of Active Psoriatic ArthritisPsoriatic ArthritisPhase 3Active not recruitingNCT04957550
Dec 14, 2026AmgenABP 234, PembrolizumabPharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)Phase 3Active not recruitingNCT06430866
Dec 14, 2026GSKInvestigational varicella vaccine, Marketed varicella vaccine, MMR vaccine and 4 moreA Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Month…ChickenpoxPhase 3RecruitingNCT06806137
Dec 15, 2026AstraZenecaGefurulimabPK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+ Generalized Myasthenia GravisGeneralized Myasthenia Gravis, gMGPhase 3RecruitingNCT06607627
Dec 15, 2026ExelixisXL092, Nivolumab, Sunitinib MalateStudy of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell CarcinomaNon-Clear Cell Renal Cell CarcinomaPhase 3Active not recruitingNCT05678673
Dec 15, 2026Gedeon Richter Ltd.CariprazineEfficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 Years of Age) With SchizophreniaSchizophreniaPhase 3RecruitingNCT03817502
Dec 15, 2026IpsenCorabotaseA Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebro…Moderate to Severe Glabellar LinesPhase 3Active not recruitingNCT07435428
Dec 15, 2026IpsenCorabotaseA Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the EyebrowsModerate to Severe Glabellar LinesPhase 3Active not recruitingNCT07427797
Dec 16, 2026Roche HoldingSatralizumabA Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methy…NMDAR Autoimmune Encephalitis, LGI1 Autoimmune EncephalitisPhase 3Active not recruitingNCT05503264
Dec 16, 2026Shanghai JMT-Bio Inc.KN026, HB1801, Pertuzumab and 3 moreA Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Bre…Early or Locally Advanced HER2-positive Breast CancerPhase 3Active not recruitingNCT06747338
Dec 17, 2026IpsenElafibranorA Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)Primary Biliary CholangitisPhase 3Active not recruitingNCT06730061
Dec 18, 2026Ausper Biopharma Co., Ltd.AHB-137, NA therapyStudy of AHB-137 in Participants With Chronic Hepatitis B (CHB) Treated With Nucleos(t)Ide Analogues (NAs)(AUSHINE)Chronic Hepatitis BPhase 3Active not recruitingNCT07246889
Dec 18, 2026Han Xu, M.D., Ph.D., FAPCR, Medical Director, IRB ChairTopotecan - usual, Topotecan - studyPharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide PolymorphismsSCLCPhase 2/3Active not recruitingNCT07145333
Dec 18, 2026Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB ChairRaloxifene - Usual, Raloxifene - StudyBioequivalence ANDA SNP Clinical Study - Raloxifene and Single Nucleotide PolymorphismsBreast CancerPhase 2/3Active not recruitingNCT06062810
Dec 20, 2026TJ Biopharma Co., Ltd.PlonmarlimabA Phase III Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of Plonmarlimab in Subjects With Relapsed/Refractory Rheumatic…Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic LymphohistiocytosisPhase 3RecruitingNCT07208058
Dec 21, 2026UCBBimekizumabA Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativ…Hidradenitis SuppurativaPhase 3Active not recruitingNCT06921850
Dec 22, 2026Adverum Biotechnologies, Inc.Ixo-vec, AfliberceptEfficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular DegenerationNeovascular Age-Related Macular Degeneration (nAMD), Wet AMDPhase 3Active not recruitingNCT06856577
Dec 22, 2026Taisho Pharmaceutical Co., Ltd.TS-172 20~60 mg/dayA Phase 3 Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis With Phosphate BindersHyperphosphatemia Patients on HemodialysisPhase 3RecruitingNCT07285291
Dec 23, 2026AstraZenecaBenralizumabA Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety…AsthmaPhase 3Active not recruitingNCT05692180
Dec 23, 2026OncoZenge ABBupiZenge 25 mg, Lidocaine viscous 2%A Clinical Study to Compare BupiZenge With Lidocaine for Pain Due to Oral Mucositis in Patients With Head and Neck Cancer.Head & Neck Cancer, Oral MucositisPhase 3RecruitingNCT07672236
Dec 23, 2026R-BioJOINTSTEMFollow-up Study for Participants of Jointstem Phase 3 Clinical TrialKnee OsteoarthritisPhase 3Active not recruitingNCT04427930
Dec 24, 2026Shanghai Kechow Pharma, Inc.Tunlametinib plus Vemurafenib, Doublets Chemotherapy ± Bevacizumab or Doublets Chemothera…Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal CancerColorectal Cancer MetastaticPhase 3RecruitingNCT06008119
Dec 25, 2026GSKInvestigational varicella vaccine_Lot 1, Investigational varicella vaccine_Lot 2, Investigational varicella vaccine_Lot 3 and 7 moreA Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of AgeChickenpoxPhase 3RecruitingNCT06740630
Dec 25, 2026Jiangsu Healthy Life Innovation Medical Technology Co., LtdTumor treating fields combined with Gemcitabine hydrochlor…, Gemcitabine hydrochloride and albumin binding paclitaxelClinical Study of Tumor Treating Fields Combined with Gemcitabine and Albumin-bound Paclitaxel in the First-line Treatment of Locally Advanc…Locally Advanced Pancreatic CancerPhase 3RecruitingNCT05653453
Dec 26, 2026CanariaBio Inc.Oregovomab, Paclitaxel, CarboplatinOregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking SurgeryCarcinoma, Ovarian Epithelial, Ovarian Neoplasms and 8 morePhase 3Active not recruitingNCT04498117
Dec 26, 2026IncytePovorcitinibA Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis SuppurativaHidradenitis Suppurativa (HS)Phase 3Active not recruitingNCT06212999
Dec 28, 2026Jiangsu Topcel-KH Pharmaceutical Co., Ltd.Human TH-SC01 cell injection, Saline solutionPhase 3 Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's DiseaseCrohn's DiseasePhase 3RecruitingNCT06925594
Dec 28, 2026PfizerPF-06821497, Docetaxel, EnzalutamideA Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Ab…Metastatic Castrate Resistant Prostate Cancer (mCRPC)Phase 3Active not recruitingNCT06551324
Dec 30, 2026AskGene Pharma, Inc.ASKB589, Oxaliplatin, Capecitabine and 1 moreASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ AdenocarcinomaGastroesophageal Junction Adenocarcinoma, Gastric AdenocarcinomaPhase 3Active not recruitingNCT06206733
Dec 30, 2026Beijing Continent Pharmaceutical Co, Ltd.Pirfenidone Capsules （400 mg）, Pirfenidone Capsules（600mg）, Pirfenidone Capsules（0mg）Pirfenidone Capsules in the Treatment of Radiation-induced Lung Injury With or Without Immune PneumoniaRadiation-induced Lung Injury, Immune-related PneumoniaPhase 2/3RecruitingNCT07388680
Dec 30, 2026Beijing Konruns Pharmaceutical Co., Ltd.KC1036, Irinotecan, Docetaxel and 1 moreA Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal CancerEsophageal Squamous Cell CarcinomaPhase 3RecruitingNCT06194734
Dec 30, 2026Cartesian TherapeuticsDecartes-08Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia GravisMyasthaenia GravisPhase 3Active not recruitingNCT06799247
Dec 30, 2026Ebima Clifford OkundayeQRX-3Use of QRX3 for Acute Tubular Necrosis Type of Renal Failure in Hospitalized Patients ( QRX-3 in ARF)Acute Renal Failure (ARF), Acute Tubular NecrosisPhase 2/3Not yet recruitingNCT07161843
Dec 30, 2026Getz PharmaAcotiamideAcotiamide vs Itopride in Postprandial Distress SyndromePostprandial Distress SyndromePhase 3Not yet recruitingNCT07174297
Dec 30, 2026Innovent BiologicsIrinotecan OR Paclitaxel or Trifluridine/tipiracil（ FTD/TPI）, IBI343A Multicenter, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (C…Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaPhase 3Active not recruitingNCT06238843
Dec 30, 2026Johnson & JohnsonCetrelimab, TAR-200, Cisplatin and 3 moreA Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (M…Urinary Bladder NeoplasmsPhase 3Active not recruitingNCT04658862
Dec 30, 2026Johnson & JohnsonSeltorexant, Selective Serotonin Reuptake Inhibitor (SSRI)/Serotonin-No…Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptom…Depressive Disorder, MajorPhase 3RecruitingNCT06559306
Dec 30, 2026Jiangsu Alphamab Biopharmaceuticals Co., LtdJSKN003, Doxorubicin, Paclitaxel and 1 moreJSKN003 in Platinum-Resistant, Relapsed Epithelial Ovarian CancerOvarian Cancer, Primary Peritoneal and 1 morePhase 3Not yet recruitingNCT06751485
Dec 30, 2026Jiangsu vcare pharmaceutical technology co., LTDVicagrel, ClopidogrelEfficacy and Safety Study of Vicagrel in Patients With Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)Phase 3RecruitingNCT06577519
Dec 30, 2026Jiangsu vcare pharmaceutical technology co., LTDVC004 CapsulesPhase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid TumorsLocally Advanced Solid TumorPhase 3RecruitingNCT06658353
Dec 30, 2026NovartiseverolimusRoll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXI…Tuberous Sclerosis ComplexPhase 3Active not recruitingNCT02962414
Dec 30, 2026PfizerVepdegestrant (ARV-471/PF-07850327), Palbociclib, LetrozoleVepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast CancerBreast CancerPhase 3Active not recruitingNCT05909397
Dec 30, 2026Quoin Pharmaceuticals Ltd.QRX003, 4% LotionClinical Study of QRX003 Lotion in Subjects With Netherton SyndromeNetherton SyndromePhase 2/3RecruitingNCT06953466
Dec 30, 2026Quoin Pharmaceuticals Ltd.QRX003, 4% LotionOpen Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton SyndromeNetherton SyndromePhase 2/3RecruitingNCT05789056
Dec 30, 2026Shanghai Jiaolian Drug Research and Development Co., LtdB007A Clinical Study of B007 in the Treatment of Generalized Myasthenia Gravis.Generalized Myasthenia GravisPhase 2/3RecruitingNCT06447597
Dec 30, 2026Sinovac BiotechRabies Vaccine (Serum-free Vero Cell), Freeze-dried, Verorab®Immunogenicity and Safety of Rabies Vaccine (Serum-free Vero Cell) in a Pre-exposure Prophylaxis RegimenRabiesPhase 3Not yet recruitingNCT07055295
Dec 30, 2026Wuhan Createrna Science and Technology Co., LtdMY008211A tabletsLong-term Safety and Tolerability of MY008211A Tablets in Patients With Paroxysmal Nocturnal HemoglobinuriaParoxysmal Nocturnal Hemoglobinuria (PNH)Phase 2/3RecruitingNCT06933914
Dec 30, 2026Xynomic Pharmaceuticals, Inc.Pazopanib, AbexinostatA Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)Renal Cell CarcinomaPhase 3RecruitingNCT03592472
Dec 31, 2026AMO Pharma LimitedTideglusibSafety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic DystrophyCongenital Myotonic DystrophyPhase 2/3RecruitingNCT05004129
Dec 31, 2026AUG TherapeuticsAVTX-803An Extension Study Assessing the Safety and Efficacy of AVTX-803 in Subjects With Leukocyte Adhesion Deficiency Type IILeukocyte Adhesion DeficiencyPhase 3RecruitingNCT05754450
Dec 31, 2026Albireo, an Ipsen CompanyOdevixibatLong-term Safety and Efficacy of Odevixibat in Patients With Alagille SyndromeAlagille SyndromePhase 3Active not recruitingNCT05035030
Dec 31, 2026Amicus Therapeuticsmigalastat HCl 150 mgA Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal DiseaseFabry DiseasePhase 3Active not recruitingNCT04020055
Dec 31, 2026Ascentage Pharma Group Internationallisaftoclax +BTK inhibitor, BTK inhibitorGlobal Trial in APG2575 for Patients With CLL/SLLCLL/SLLPhase 3RecruitingNCT06104566
Dec 31, 2026AstraZenecaDurvalumabRoll Over StudY for Patients Who Have Completed a Previous Oncology Study With DurvalumabCancerPhase 3Enrolling by invitationNCT05303532
Dec 31, 2026BeOne Medicines Ltd.Zanubrutinib, TislelizumabA Study to Evaluate Long-term Safety of Zanubrutinib Regimens in Participants With B-Cell Malignancies Who Participated in BeiGene Parent St…B-cell MalignanciesPhase 3Active not recruitingNCT04170283
Dec 31, 2026Biocity Biopharmaceutics Co., Ltd.SC0062 strength 10mgA Study of SC0062 Capsule for the Treatment of IgA Nephropathy with ProteinuriaIgA Nephropathy (IgAN)Phase 3RecruitingNCT06819826
Dec 31, 2026Boehringer IngelheimBI 690517, EmpagliflozinEASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)Kidney Disease, ChronicPhase 3Active not recruitingNCT06531824
Dec 31, 2026Changchun GeneScience Pharmaceutical Co., Ltd.Nano-crystalline Megestrol Acetate Oral Suspension, standard treatmentNano-crystalline Megestrol Acetate Combined With Standard Treatment Versus Standard Treatment for First-line Extensive-stage Small Cell Lung…Extensive-stage Small Cell Lung Cancer (ES-SCLC), The Pre-cachexia or Cachexia Patients Who Have Not Received Systemic Treatment and Are Not Eligible for Curative TherapyPhase 3Not yet recruitingNCT06961201
Dec 31, 2026Clarity Pharmaceuticals Ltd64Cu-SAR-bisPSMA64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate CancerProstate Cancer, Prostate Cancer Patients With Detectable PSA Following Prostatectomy and 4 morePhase 3Active not recruitingNCT06970847
Dec 31, 2026Cloudbreak Therapeutics, LLCCBT-001A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With PterygiumPterygiumPhase 3Active not recruitingNCT05456425
Dec 31, 2026Corza Medical GmbHTachoSil, Surgicel OriginalA Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding …HemorrhagePhase 3RecruitingNCT06664775
Dec 31, 2026EisaiLecanemab IV, Lecanemab SCA Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's DiseaseEarly Alzheimer's DiseasePhase 3Active not recruitingNCT03887455
Dec 31, 2026Galderma Group AG/ADRTrifaroteneA Study to Compare the Efficacy, Safety and Pharmacokinetics of Trifarotene 50 mcg/g Cream in Chinese Subjects With Acne VulgarisAcne VulgarisPhase 3Active not recruitingNCT07186413
Dec 31, 2026GeneCradle IncGC101 adeno-associated virus injectionSafety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular …SMA - Spinal Muscular AtrophyPhase 3RecruitingNCT06971094
Dec 31, 2026Guangzhou JOYO Pharma Co., LtdSC1011SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF)Idiopathic Pulmonary FibrosisPhase 2/3RecruitingNCT06125327
Dec 31, 2026HK inno.N CorporationIN-B00009Study to Evaluate the Efficacy and Safety of IN-B00009 Injection in Adults With Obesity or Overweight Without Diabetes MellitusObesity &Amp; OverweightPhase 3Not yet recruitingNCT07192263
Dec 31, 2026Hangzhou Gensciences Biopharmaceutical Co., Ltd.FRSW107Study of Efficacy and Safety of FRSW107 in Pediatric Patients With Severe Hemophilia ASevere Hemophilia APhase 3Not yet recruitingNCT06136507
Dec 31, 2026Hangzhou Highlightll Pharmaceutical Co., LtdTLL-018A Long-term Extension Clinical Study of TLL-018 in Patients With Rheumatoid ArthritisRheumatoid ArthritisPhase 3Active not recruitingNCT06887127
Dec 31, 2026Roche HoldingPertuzumab, Trastuzumab, Other Combination Anti-Cancer TherapiesA Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertu…Solid TumorsPhase 3Active not recruitingNCT02320435
Dec 31, 2026Roche HoldingInavolisib, Phesgo, Taxane-based Chemotherapy and 1 moreA Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participan…Metastatic Breast CancerPhase 3RecruitingNCT05894239
Dec 31, 2026Innovent BiologicsIBI362, semaglutideA Study Comparing IBI362 vs Semaglutide in Chinese Overweight or Obese Adults With Metabolic Dysfunction-associated Fatty Liver Disease （MAF…Overweight, Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)Phase 3Active not recruitingNCT06884293
Dec 31, 2026Innovent BiologicsIBI311A Clinical Study to Evaluate the Efficacy and Safety of IBI311 in Subjects With Inactive Thyroid Eye DiseaseThyroid Eye DiseasePhase 3RecruitingNCT07113262
Dec 31, 2026INSMED IncTreprostinil PalmitilAn Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)Pulmonary Arterial HypertensionPhase 2/3Active not recruitingNCT05649748
Dec 31, 2026Iperboreal Pharma SrlXyloCore Low Strenght, XyloCore Medium Strenght, XyloCore …, 1.36%, 1.5%, 2.27%, 2.5%, 3.86%, 2.25% Glucose PD SolutionEfficacy and Safety of XyloCore Peritoneal Dialysis Solution.End Stage Renal DiseasePhase 3RecruitingNCT03994471
Dec 31, 2026Johnson & JohnsonIbrutinibA Long-term Extension Study of PCI-32765 (Ibrutinib)Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma and 5 morePhase 3Active not recruitingNCT01804686
Dec 31, 2026Jiangsu Hengrui MedicineSHR-A1811, Pyrotinib in combination with Capecitabine.A Trial of SHR-A1811versus Pyrotinib in Combination With Capecitabine in HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subject…HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With Trastuzumab and TaxanePhase 3Active not recruitingNCT05424835
Dec 31, 2026Jiangsu Hengrui MedicineFuzuloparib , Abiraterone acetate and PrednisoneA Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone …Metastatic Castration-Resistant Prostate Cancer (mCRPC)Phase 3Active not recruitingNCT04691804
Dec 31, 2026Jiangsu Hengrui MedicineHRS-9190, RocuroniumSafety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation and Bolus Maintenance in AdultsNeuromuscular BlockadePhase 3RecruitingNCT07746726
Dec 31, 2026Kartos Therapeutics, Inc.Navtemadlin, RuxolitinibStudy of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to RuxolitinibMyelofibrosis, Post-PV MF and 3 morePhase 3RecruitingNCT06479135
Dec 31, 2026Laboratorios Silanes S.A. de C.V.Etoricoxib + Betamethasone fixed dose, Etoricoxib fixed doseEfficacy Anda Safety of Etoricoxib With Betamethasone for the Treatment of Acute Gout ArthritisGout Arthritis, Gout AttackPhase 3RecruitingNCT06863701
Dec 31, 2026Longboard Pharmaceuticals, Inc.LP352A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)Dravet SyndromePhase 3Active not recruitingNCT06660394
Dec 31, 2026Materia Medica HoldingRaphaminClinical Trial of the Efficacy and Safety of Raphamin in Prevention of Recurrences of Chronic Bacterial CystitisCystitis Chronic, Cystitis Bacterial and 1 morePhase 3Active not recruitingNCT06284265
Dec 31, 2026NaviFUS CorporationBevacizumab, Microbubble, Low-Intensity Focused UltrasoundA Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused U…Glioblastoma Multiforme, Glioblastoma and 6 morePhase 3RecruitingNCT06496971
Dec 31, 2026Olatec Therapeutics, Inc.DapansutrileStudy of Dapansutrile Tablets in Subjects With an Acute Gout FlareAcute Gout Flare, Gout Attack and 5 morePhase 2/3RecruitingNCT05658575
Dec 31, 2026PT Bio FarmaQuadrivalent Human Papillomavirus (Types 6,11,16,18) Recom…, Tetanus-Diphtheria boosterImmunogenicity and Safety of HPV-4 Vaccine With or Without Td Vaccine in ChildrenHuman Papillomavirus (HPV) InfectionPhase 3Not yet recruitingNCT07824310
Dec 31, 2026PfizerAvelumab, Lorlatanib, Talazoparib and 5 moreContinued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are ClosingAdvanced Malignancies, NSCLC and 3 morePhase 3Active not recruitingNCT05059522
Dec 31, 2026Qilu Pharmaceutical Co., Ltd.QL2107, Keytruda®Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)Carcinoma, Non-Small-Cell LungPhase 3Not yet recruitingNCT07162883
Dec 31, 2026RemeGen Co., Ltd.RC48-ADC, Toripalimab, Gemcitabine and 2 moreA Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial CarcinomaUrothelial Carcinoma, HER2-expressingPhase 3RecruitingNCT05302284
Dec 31, 2026RemeGen Co., Ltd.TelitaciceptA Study of Telitacicept in Patients With Ocular Myasthenia Gravis (OMG)Myasthenia Gravis, OcularPhase 3RecruitingNCT07249632
Dec 31, 2026Serum Institute of India Pvt. Ltd.Cervavac as three dose regimen, Cervavac as two dose regimen, Gardasil as three dose regimenClinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 YearsHuman Papillomavirus InfectionPhase 3Active not recruitingNCT06281119
Dec 31, 2026Shanghai Jiaolian Drug Research and Development Co., LtdB007A Clinical Study of B007 in the Treatment of Pemphigus.PemphigusPhase 2/3RecruitingNCT06454357
Dec 31, 2026Shanghai Jiaolian Drug Research and Development Co., LtdB007, Cyclosporin CapsulesA Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.Primary Membranous NephropathyPhase 2/3RecruitingNCT06470191
Dec 31, 2026Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.SKB264, Eribulin, Capecitabine and 2 moreStudy of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast CancerMetastatic Breast CancerPhase 3RecruitingNCT06081959
Dec 31, 2026TRB ChemedicaArtrodarEvaluation of the Structural Modification Effect of Diacerein (Artrodar®) in Knee Osteoarthritic PatientsKnee OsteoarthritisPhase 3Active not recruitingNCT04318041
Dec 31, 2026Tasly Pharmaceutical Group Co., LtdLianxiaxiaopi Granules, a simulated agent of Lianxiaxiaopi GranulesA Study of Lianxiaxiaopi Granules in the Treatment of Postprandial Distress SyndromePostprandial Distress SyndromePhase 3RecruitingNCT06696261
Dec 31, 2026Tasly Pharmaceutical Group Co., LtdJS1-1-01 low-dose group, JS1-1-01 high-dose groupA Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe DepressionDepressionPhase 2/3Not yet recruitingNCT07485595
Dec 31, 2026ViatrisCenerimodA Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus ErythematosusLupus Erythematosus, SystemicPhase 3Active not recruitingNCT05672576
Dec 31, 2026VIR BiotechnologyTobevibart, ElebsiranA Study to Evaluate Tobevibart + Elebsiran in Chronic HDV InfectionViral HepatitisPhase 3Active not recruitingNCT06903338
Dec 31, 2026VivaVision Biotech, IncVVN461 Ophthalmic Solution 1.0%, 1.0% prednisolone acetateA Phase 3 Study of VVN461 Ophthalmic Solution for Noninfectious Anterior UveitisNon-infectious Anterior UveitisPhase 3Active not recruitingNCT07136805
Dec 20263D Medicines3D1002 (50 mg)(Phase IIa), 3D1002 (100 mg)(Phase IIa), 3D1002 (150 mg)(Phase IIa) and 3 more3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer PainCancer PainPhase 2Not yet recruitingNCT05265052
Dec 20263D Medicines (Sichuan) Co., Ltd.Envafolimab+Lenvatinib, EnvafolimabStudy of Envafolimab Alone or With Lenvatinib in Patients With Advanced Endometrial CancerAdvanced Endometrial CancerPhase 2RecruitingNCT05112991
Dec 20263D Medicines (Sichuan) Co., Ltd.Lenvatinib + Envafolimab, SunitinibPhase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid TumorsSolid Tumors, Non-small Cell Lung Cancer and 2 morePhase 1/2RecruitingNCT05024214
Dec 2026858 Therapeutics, Inc.ETX-19477A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid MalignanciesAdvanced or Metastatic Solid Tumors, Breast Cancer and 11 morePhase 1/2RecruitingNCT06395519
Dec 2026A2 Biotherapeutics Inc.A2B530, xT-Onco with HLA-LOH AssayA Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost…Solid Tumor, Adult, Solid Tumor and 14 morePhase 1/2Active not recruitingNCT05736731
Dec 2026AP Biosciences Inc.AP203A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tu…Locally Advanced or Metastatic Solid Tumors, Non Small Cell Lung Cancer (NSCLC) and 2 morePhase 1/2RecruitingNCT05473156
Dec 2026Aadi Bioscience, Inc.nab-sirolimusTrial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial CancerEndometrial Cancer, Endometrioid Tumor and 4 morePhase 2RecruitingNCT05997017
Dec 2026AbbVieABBV-400, Bevacizumab, Folinic Acid and 2 moreStudy to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 W…Unresectable Metastatic Colorectal CancerPhase 2Active not recruitingNCT06107413
Dec 2026Abivax S.A.ObefazimodEfficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's DiseaseModerately to Severely Active Crohn DiseasePhase 2RecruitingNCT06456593
Dec 2026Adicet TherapeuticsADI-270, Fludarabine, CyclophosphamideA Phase 1/2 Trial of ADI-270 in ccRCCClear Cell Renal Cell CarcinomaPhase 1/2Active not recruitingNCT06480565
Dec 2026AkesoAK129(dose 1), Pemetrexed, Paclitaxel and 9 moreAK129 Combination Therapy for Advanced Solid TumorsNon-small Cell Lung Cancer Stage IIIB/IV, Head and Neck Squamous Cell Carcinoma (HNSCC) and 2 morePhase 1/2RecruitingNCT06943820
Dec 2026AkesoAK119, AK112Study of AK119 Combined With AK112 in Patients With Advanced Solid TumorsSolid Tumor, AdultPhase 1/2RecruitingNCT05689853
Dec 2026Alto Neuroscience, Inc.ALTO-300Study of ALTO-300 in MDDMajor Depressive DisorderPhase 2RecruitingNCT05922878
Dec 2026Alyssum TherapeuticsAT-1965 Liposome InjectionStudy to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients …Solid TumorPhase 1/2RecruitingNCT06234098
Dec 2026Alzamend Neuro, Inc.AL001, Lithium carbonateA Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Li…Bipolar I DisorderPhase 1/2RecruitingNCT07540338
Dec 2026Ambrx, Inc.ARX788ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)HER2 Positive Metastatic Breast CancerPhase 2Active not recruitingNCT04829604
Dec 2026Amydis Inc.AMDX-2011PA Study of AMDX-2011P in Participants With CAACerebral Amyloid AngiopathyPhase 2RecruitingNCT05709314
Dec 2026Angitia BiopharmaceuticalsAGA2118A Trial Evaluating Efficacy of AGA2118 in PostMenopausal Women wIth Low Bone MasS (ARTEMIS)Postmenopausal OsteoporosisPhase 2Active not recruitingNCT06577935
Dec 2026Ascentage Pharma Group InternationalAPG2575Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLLChronic Lymphocytic Leukemia, Small Lymphocytic LymphomaPhase 2RecruitingNCT05147467
Dec 2026Avalyn Pharma Inc.AP02AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02 (Nintedanib Solution) in IPFIdiopathic Pulmonary Fibrosis (IPF)Phase 2RecruitingNCT07194382
Dec 2026Aveta Biomics, Inc.APG-157Safety and Efficacy of APG-157 in Head and Neck CancerHead and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity and 1 morePhase 2Active not recruitingNCT05312710
Dec 2026Beam TherapeuticsBEAM-201A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphobl…Lymphoblastic Lymphoma, T-Cell Lymphoblastic Leukemia/Lymphoma and 1 morePhase 1/2Active not recruitingNCT05885464
Dec 2026Beijing Scitech-Mq Pharmaceuticals LimitedST-1898 tabletsA Study of ST-1898 for Unresectable or Metastatic MelanomaUnresectable or Metastatic MelanomaPhase 1/2RecruitingNCT06359860
Dec 2026BioCardia, Inc.CardiALLO™ Human Allogenic Culture-expanded Bone marrow-de…, Diagnostic CatheterizationClinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem CellsHeart Failure, SystolicPhase 1/2Active not recruitingNCT05925608
Dec 2026BioRestorative Therapies, Inc.BRTX-100A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)Lumbar Disc DiseasePhase 2RecruitingNCT04042844
Dec 2026Biohaven PharmaceuticalsBHV-7000Long-term Safety and Tolerability of BHV-7000Focal EpilepsyPhase 2Enrolling by invitationNCT06443463
Dec 2026Bivision Pharmaceuticals, Inc.Lutetium Lu 177 JH020002 InjectionPhase 1/2 Clinical Study of Lutetium Lu 177 JH020002 Injection in Patients With Advanced Prostate CancerProstate CancerPhase 1/2RecruitingNCT06139575
Dec 2026COUR Pharmaceutical Development Company, Inc.CNP-103CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)Type 1 Diabetes Mellitus, T1D and 8 morePhase 1/2RecruitingNCT06783309
Dec 2026Cancer Vaccines LimitedACIT-1Investigation of a Therapeutic Vaccine (ACIT-1) in CancerCancer, NeoplasmsPhase 1/2Active not recruitingNCT03096093
Dec 2026Centessa Pharmaceuticals plcORX750A Study of ORX750 in Participants With Narcolepsy and Idiopathic HypersomniaNarcolepsy Type 1, Narcolepsy Type 2 and 1 morePhase 2RecruitingNCT06752668
Dec 2026Jiangsu Hengrui MedicineHRS-3095 TabletA Clinical Trial of HRS-3095 in Patients With Chronic Spontaneous UrticariaChronic Spontaneous UrticariaPhase 2Not yet recruitingNCT07613866
Dec 2026Sino Biopharmaceutical LimitedTQB3702 TabletsClinical Trial of TQB3702 Tablets in Subjects With Systemic Lupus Erythematosus (SLE)Systemic Lupus ErythematosusPhase 2Not yet recruitingNCT06859931
Dec 2026Sino Biopharmaceutical LimitedTQB2930 for injection, Paclitaxel for injection (albumin-bound), TQB3616 capsule and 5 moreA Study of TQB2930 for Injection Monotherapy or Combination Therapy in Patients With Recurrent/Metastatic Breast CancerMetastatic Breast Cancer, Recurrent Breast Cancer and 1 morePhase 1/2RecruitingNCT06202261
Dec 2026Sino Biopharmaceutical LimitedTQ05105 Tablets, TQB3617 CapsulesA Clinical Trial of TQ05105 Tablets Combined With TQB3617 Capsules in the Treatment of Myelofibrosis (MF)MyelofibrosisPhase 1/2RecruitingNCT06122831
Dec 2026Sino Biopharmaceutical Limited–Efficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection (TQA2225/AP025) in Adult Subjects With Non-alcoholic Steatohe…Non-alcoholic SteatohepatitisPhase 2RecruitingNCT06569524
Dec 2026CivaTech OncologyCivaSheetFeasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®Lung Cancer, Lung Cancer Stage I and 1 morePhase 2RecruitingNCT03290534
Dec 2026Connect Biopharm LLCRademikibartRademikibart IV for Acute Asthma and COPD ExacerbationAsthma Acute, COPD Exacerbation AcutePhase 2RecruitingNCT07705737
Dec 2026Corcept TherapeuticsrelacorilantExtension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing SyndromeCushing SyndromePhase 2Active not recruitingNCT03604198
Dec 2026Delcath Systems, Inc.Melphalan/HDS Followed by Consolidation Treatment with Tri…, Trifluridine-tipiracil plus Bevacizumab AloneEvaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Canc…Refractory Metastatic Colorectal CancerPhase 2RecruitingNCT06607458
Dec 2026Denali Therapeutics Inc.DNL593A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With…Frontotemporal DementiaPhase 1/2Active not recruitingNCT05262023
Dec 2026Design Therapeutics, Inc.DT-216P2A Multiple Ascending Dose Study of DT-216P2 in Patients With Friedreich's AtaxiaFriedreich AtaxiaPhase 1/2RecruitingNCT06874010
Dec 2026Dianthus TherapeuticsClaseprubartA Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor NeuropathyMultifocal Motor NeuropathyPhase 2Active not recruitingNCT06537999
Dec 2026Dizal PharmaceuticalsDZD9008+AZD4205A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)Non-small Cell Lung CancerPhase 2RecruitingNCT06295432
Dec 2026Dogwood Therapeutics, Inc.Halneuron, Halneuron (Open Label Extension)Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic PainChemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy and 1 morePhase 2Active not recruitingNCT06848348
Dec 2026Dong-A St CO., LtdDA-2811, DA-2811-CClinical Trial to Evaluate the Efficacy and Safety of DA-2811 When Added to Ongoing BT-1 and BT-2 Combination Therapy in Patients With Type …Diabete MellitusPhase 2Not yet recruitingNCT07239440
Dec 2026Dren BioDR-01A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic LymphomasLGLL - Large Granular Lymphocytic Leukemia, Primary Cutaneous Gamma-Delta T-Cell Lymphoma and 11 morePhase 1/2RecruitingNCT05475925
Dec 2026EicOsis Human Health Inc.EC5026 oral tabletSafety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)Parkinson's Disease (PD)Phase 1/2RecruitingNCT07142044
Dec 2026Eikon Therapeutics, Inc.EIK1001, Pembrolizumab, Paclitaxel and 2 moreA Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLCNSCLCPhase 2Active not recruitingNCT06246110
Dec 2026Eli Lilly and CompanyLY3537021, Background ChemotherapyA Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With CancerNausea, Vomiting and 2 morePhase 2RecruitingNCT07169851
Dec 2026Elion Therapeutics, Inc.EL219, Active Comparator- IV Antifungal (LAmB or voriconazole)Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal TherapyInvasive Mould InfectionPhase 2RecruitingNCT07215273
Dec 2026Enanta Pharmaceuticals InczelicapavirA Phase 2 Study to Investigate the Efficacy and Safety of Zelicapavir in Participants Aged ≥28 Days to ≤36 Months of Age Infected With Respi…RSV Infection, RSV and 1 morePhase 2RecruitingNCT07482657
Dec 2026Enveda TherapeuticsENV-294ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in AdultsAsthmaPhase 2RecruitingNCT07301255
Dec 2026Enveda TherapeuticsENV-294Study of ENV-294 in Adults With Moderate-to-Severe Atopic DermatitisAtopic Dermatitis (AD)Phase 2RecruitingNCT07298395
Dec 2026Eupraxia Pharmaceuticals INC.EP-104GI, Matching vehicle controlA Trial to Evaluate EP-104GI in Adults With Eosinophilic Esophagitis (EoE).Eosinophilic EsophagitisPhase 1/2RecruitingNCT05608681
Dec 2026Filament Health Corp.PEX010-Assisted TherapyPEX010-Assisted Therapy for Opioid Use Disorder (OUD): a Feasibility StudyOpioid Use DisorderPhase 2Not yet recruitingNCT06608459
Dec 2026Frantz Viral Therapeutics, LLCArtesunate ointmentPhase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)Vulvar Diseases, HPV Infection and 11 morePhase 2RecruitingNCT06075264
Dec 2026Fujian Shengdi Pharmaceutical Co., Ltd.HRS-9563 Injection, sodium chloride injectionPhase II Clinical Study of HRS-9563 in Patients With Mild to Moderate HypertensionMild to Moderate HypertensionPhase 2Active not recruitingNCT07297797
Dec 2026Fujian Shengdi Pharmaceutical Co., Ltd.HRS5580 for injection combined with palonosetron hydrochlo…, HRS5580 for injection combined with palonosetron hydrochlo…, HRS5580 for injection blank preparation combined with palo…A Clinical Trial of HRS5580 for Injection Combined With Palonosetron Hydrochloride for the Prevention of Postoperative Nausea and VomitingPrevention of Postoperative Nausea and VomitingPhase 2RecruitingNCT07709897
Dec 2026GE HealthCareRegadenosonA Study to Evaluate the Safety and Pharmacokinetics of Regadenoson in Pediatric PatientsMyocardial Ischemia, Coronary Artery DiseasePhase 1/2RecruitingNCT04604782
Dec 2026Galderma Group AG/ADRnemolizumabProof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPU…Chronic Pruritus of Unknown OriginPhase 2Active not recruitingNCT07074977
Dec 2026GeneCradle IncGC301Evaluation of the Safety and Efficacy of Late-onset Pompe Disease Gene Therapy DrugPompe Disease (Late-onset)Phase 1/2RecruitingNCT06391736
Dec 2026GeneCradle IncGC101Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 PatientsSpinal Muscular Atrophy Type 3Phase 1/2RecruitingNCT06421831
Dec 2026GeneCradle IncGC101Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 1 PatientsSpinal Muscular AtrophyPhase 1/2RecruitingNCT05824169
Dec 2026Georgiamune IncGIM-531, Anti-PD-1 monoclonal antibodySafety and Tolerability Study of GIM-531 in Advanced Solid TumorsMelanoma Stage IV, Solid TumorPhase 1/2RecruitingNCT06425926
Dec 2026Guangzhou Gloria Biosciences Co., Ltd.GLS-012, GLS-010Immuno-Oncology Drugs GLS-012 Alone & in Combination GLS-010 Treating With Advanced Patients Solid TumorsSolid TumorPhase 1/2RecruitingNCT05909436
Dec 2026Henan Genuine Biotech Co., Ltd.CL-197 capsulesA Phase Ⅱa Clinical Study of CL-197 CapsulesHIV-1 InfectionPhase 2RecruitingNCT07308782
Dec 2026Heron Neutron Medical Corp.F18 FBPA InjectionA Study to Evaluate the Safety and Diagnostic Performance of F18 FBPA PET/CT Imaging in Solid TumorsSolid TumorPhase 1/2RecruitingNCT07691775
Dec 2026Highlight TherapeuticsBO-112Clinical Trial to Evaluate BO-112 in Patients With Basal Cell Carcinoma (BCC)Basal Cell CarcinomaPhase 2Active not recruitingNCT06422936
Dec 2026Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.HW211026A Phase 2 Study of HW211026Actinic KeratosisPhase 2Not yet recruitingNCT07513454
Dec 2026Imbria Pharmaceuticals, Inc.Ninerafaxstat 200mg MRA Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic CardiomyopathyNon-obstructive Hypertrophic CardiomyopathyPhase 2RecruitingNCT07023614
Dec 2026Ingenia Therapeutics INCIGT-303A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney DiseaseHealthy Volunteers, Chronic Kidney DiseasePhase 1/2RecruitingNCT07231679
Dec 2026Institut de Recherches Internationales Servier (I.R.I.S.)BN104 monotherapy, BN104 monotherapy - rp2dA Study of BN104 in the Treatment of Acute LeukemiaALL, Adult, AML, Adult and 5 morePhase 1/2Active not recruitingNCT06052813
Dec 2026Iperboreal Pharma SrlPolyCore (Polydextrin, L-Carnitine, D-xylitol)Peritoneal Ultrafiltration in Cardio Renal Syndrome.Congestive Heart FailurePhase 1/2RecruitingNCT03994874
Dec 2026ItalfarmacogivinostatLong-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative NeoplasmsChronic Myeloproliferative NeoplasmsPhase 2Active not recruitingNCT01761968
Dec 2026Jiangsu Hengrui MedicineHRS-6209 Capsules, Letrozole Tablets, HRS-2189 TabletsA Clinical Study of HRS-6209 Combined With Other Treatment Regimens in Patients With Breast CancerBreast CancerPhase 1/2RecruitingNCT06974929
Dec 2026Jiangsu Hengrui MedicineHRS-5041 tablets, Abiraterone Acetate tablets（II）, Prednisone Acetate tablets and 5 moreA Study of HRS-5041 Tablets Combined With Antitumor Therapy in Subjects With Advanced Prostate CancerProstate CancerPhase 1/2RecruitingNCT06568094
Dec 2026Jiangsu Hengrui MedicineSHR-A1811 & Pyrotinib/SHR-A1811 & SHR-1316A Trial of Injectable SHR-A1811 in Combination With Pyrotinib or SHR-1316 in Subjects With Advanced Non-small Cell Lung CancerAdvanced Non-small Cell Lung CancerPhase 1/2RecruitingNCT05482568
Dec 2026Jiangsu Hengrui MedicineSHR-3167 InjectionA Study Comparing Safety and Efficacy of SHR-3167 Fixed-Dose Titration and Individualized-Dose Titration in Adults With Type 2 Diabetes Inad…Diabetes Mellitus, Type 2Phase 2Active not recruitingNCT07472725
Dec 2026Jina Pharmaceuticals Inc.50 mg cabazitaxel, 100 mg cabazitaxel, 200 mg cabazitaxelA Study to Investigate Efficacy and Safety of Different Dose Regimen of Oral Cabazitaxel Tablet in Adult Participants with Prostate CancerMetastatic Castration-resistant Prostate Cancer, MCRPCPhase 2Not yet recruitingNCT06890832
Dec 2026Kardigan, Inc.TonlamarsenStudy of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertens…Hypertension, Acute Severe Hypertension and 2 morePhase 2RecruitingNCT07511361
Dec 2026Karyopharm Therapeutics Inc.SelinexorSelinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)Diffuse Large B-cell LymphomaPhase 2Active not recruitingNCT02227251
Dec 2026Keymed Biosciences Co.LtdCM336_group 1, CM336_group 2a, CM336_group 2b and 12 moreA Study of CM336 in Patients With Relapsed or Refractory Multiple MyelomaMultiple MyelomaPhase 1/2RecruitingNCT05299424
Dec 2026Kind Pharmaceuticals LLCAND017 capsulesA Study of Safety and Efficiency of AND017 in Patients With β-thalassemiaβ -ThalassemiaPhase 2RecruitingNCT06302491
Dec 2026Kind Pharmaceuticals LLCAND017A Study of Efficacy and Safety of AND017 in Patients With Myelodysplastic SyndromeMyelodysplastic SyndromesPhase 2RecruitingNCT06304103
Dec 2026Gilead Sciencesanitocabtagene-autoleucelStudy of Anitocabtagene-autoleucel in Relapsed or Refractory Multiple Myeloma (iMMagine-1)Multiple MyelomaPhase 2Active not recruitingNCT05396885
Dec 2026Krystal Biotech, Inc.KB801A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic KeratitisNeurotrophic KeratitisPhase 1/2RecruitingNCT06999733
Dec 2026LaNova Medicines LimitedLM-299Study of LM-299 in Subjects Advanced Malignant TumorsMalignant TumorsPhase 1/2RecruitingNCT06650566
Dec 2026Lamassu Bio IncSA53-OS (phase 1), SA53-OS (phase 2)Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid TumorsSolid TumorPhase 1/2RecruitingNCT06578624
Dec 2026Lantern Pharma Inc.LP-300, Pemetrexed, CarboplatinA Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung AdenocarcinomaAdenocarcinoma of Lung, Carcinoma, Non-Small-Cell LungPhase 2RecruitingNCT05456256
Dec 2026Latticon Antibody Therapeutics, IncLAT010, LAT010 + ICIA First-in-Human, Phase 1/2 Study of LAT010 in Patients With Advanced Solid Tumors (LIGHTSPEED-1)Advanced Solid TumorPhase 1/2RecruitingNCT06277219
Dec 2026Lexeo Therapeutics, Inc.LX2020Gene Therapy for ACM Due to a PKP2 Pathogenic VariantArrhythmogenic Cardiomyopathy, PKP2-ACM and 1 morePhase 1/2Active not recruitingNCT06109181
Dec 2026Lion TCR Pte. Ltd.LioCyx-M, LenvatinibStudy of HBV-TCR T Cells (LioCyx-M) as Monotherapy or as Combination With Lenvatinib for HBV-related HCCHepatocellular Carcinoma, Liver Cancer, Adult and 1 morePhase 2Not yet recruitingNCT05195294
Dec 2026Lumicell, Inc.LUM015, LUM 2.6 Imaging DeviceFeasibility of the LUM Imaging System for Detection of Gastrointestinal CancersColorectal Cancer, Pancreatic Cancer and 2 morePhase 1/2RecruitingNCT02584244
Dec 2026Mabwell (Shanghai) Bioscience Co., Ltd.9MW3811 InjectionA Phase II Study of 9MW3811 in Patients With Pathological ScarScarPhase 2RecruitingNCT07576608
Dec 2026Meribank Biotech Co., Ltd.umbilical cord mesenchymal stem cellsMesenchymal Stem Cells for Frailty SyndromePathologic ProcessesPhase 1/2Active not recruitingNCT06501066
Dec 2026NMD Pharma A/SNMD670Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia GravisMyasthenia Gravis, Myasthenia Gravis, MuSKPhase 2RecruitingNCT06414954
Dec 2026NS Pharma, Inc.NS-229Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With PolyangiitisEosinophilic Granulomatosis With Polyangiitis, Churg-Strauss SyndromePhase 2Active not recruitingNCT06046222
Dec 2026Nanjing Leads Biolabs Co.,LtdLBL-024 for InjectionA Phase I/II Clinical Study of LBL-024 in Patients With Advanced Malignant TumorsAdvanced Solid TumorPhase 1/2RecruitingNCT05170958
Dec 2026Newsoara HYK Biopharmaceutical (Shanghai) Co., Ltd.Olvi-Vec, platinum (cisplatin or carboplatin), EtoposideOlvi-Vec Combined With Platinum Plus Etoposide Therapy in Patients With Late Phase SCLCSCLC, Extensive StagePhase 1/2RecruitingNCT07136285
Dec 2026Nexcella Inc.NXC-201 CAR-TStudy of NXC-201 CAR-T in Patients With Light Chain (AL) AmyloidosisLight Chain (AL) AmyloidosisPhase 1/2Active not recruitingNCT06097832
Dec 2026Next Life SciencesOcclusion SystemPlan A Occlusion and Reversal System Feasibility StudyFertility, Fertility, Male and 1 morePhase 2RecruitingNCT07361120
Dec 2026NoNO Inc.NoNO-42NoNO-42 Trial in Acute Ischemic Stroke Patients Selected for Thrombolysis With or Without Endovascular ThrombectomyAcute Ischemic StrokePhase 2RecruitingNCT06403267
Dec 2026Omeros CorpOMS906 study drugLong-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal HemoglobinuriaParoxysmal Nocturnal HemoglobinuriaPhase 2Active not recruitingNCT06298955
Dec 2026One-carbon Therapeutics ABTH9619Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid TumorsSolid Tumor, Colorectal Cancer (CRC) and 4 morePhase 1/2RecruitingNCT07151040
Dec 2026OriCell Therapeutics Co., Ltd.Ori-C101Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCCHepatocellular CarcinomaPhase 1/2RecruitingNCT05652920
Dec 2026PT. Prodia Stem Cell IndonesiaControl (NaCl 0.9%), UC-MSC, UC-MSC and SecretomeMesenchymal Stem Cells (MSCs) and Conditioned Medium Mesenchymal Stem Cells as Adjuvant Therapy for SepsisAcute Respiratory Distress SyndromePhase 1/2RecruitingNCT07439848
Dec 2026Panafina, Inc.RABI-767A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute PancreatitisAcute PancreatitisPhase 2RecruitingNCT06080789
Dec 2026Phoenix Molecular DesignsPMD-026, fulvestrantPhase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast CancerMetastatic Breast CancerPhase 1/2Active not recruitingNCT04115306
Dec 2026Protara TherapeuticsTARA-002Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Year…Lymphatic MalformationPhase 2RecruitingNCT05871970
Dec 2026Pulmovant, Inc.inhaled mosliciguat, Dry Powder InhalerA Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILDPulmonary Hypertension, Interstitial Lung Disease (ILD) and 4 morePhase 2RecruitingNCT07333183
Dec 2026Qilu Pharmaceutical Co., Ltd.Dose 1 of QLS1410, Dose 2 of QLS1410, Dose 3 of QLS1410QLS1410 in Participants With Uncontrolled HypertensionHypertension (HTN)Phase 2Enrolling by invitationNCT07489612
Dec 2026Qilu Pharmaceutical Co., Ltd.QLC5508, abiraterone acetate, enzalutamide and 1 moreA Clinical Study of QLC5508 and/or QLH12016 in Combination With Other Anti-tumor Therapies in Subjects With Advanced Prostate CancerAdvanced Prostate CancerPhase 1/2RecruitingNCT07198633
Dec 2026Qilu Pharmaceutical Co., Ltd.QLS31905 for Injection, QL2107 Injection, Oxaliplatin Injection and 1 moreCombination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gast…Gastric Adenocarcinoma, Gastroesophageal Junction AdenocarcinomaPhase 2Not yet recruitingNCT06942767
Dec 2026Ranok Therapeutics (Hangzhou) Co., Ltd.RNK08954-01A Study of RNK08954 in Subjects With Advanced Solid Tumors With KRAS ((Kirsten Rat Sarcoma) G12D MutationKRAS G12D MutationPhase 1/2RecruitingNCT06667544
Dec 2026ReAlta Life Sciences, Inc.RLS-0071A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hyp…Hypoxic-Ischemic EncephalopathyPhase 2RecruitingNCT05778188
Dec 2026ReAlta Life Sciences, Inc.RLS-0071Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host D…Steroid Refractory GVHDPhase 2RecruitingNCT06343792
Dec 2026Regenerative Ocular Immunobiologics LLCd-MAPPS, PI and Patient MaskedStudy of d-MAPPS™ Ophthalmic Solution, Safety, Tolerability, and Efficacy in the Treatment of Chronic Ocular Graft-Versus-Host Disease (oGVH…oGHVDPhase 1/2Active not recruitingNCT06852768
Dec 2026Rottapharm BiotechCR6086, AGEN2034Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI CancersRefractory Metastatic Colorectal Cancer, Solid Tumor and 4 morePhase 1/2Active not recruitingNCT05205330
Dec 2026Ryvu Therapeutics SARVU120, RuxolitinibRVU120 Rollover StudyAdvanced Solid Tumors, Acute Myeloid Leukaemia (AML) and 1 morePhase 2Enrolling by invitationNCT06987058
Dec 2026Ryvu Therapeutics SAMEN1703, GlofitamabMEN1703 (SEL24) to Treat Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma (JASPIS-01)Non-Hodgkin Lymphoma, B-cellPhase 2RecruitingNCT06534437
Dec 2026SCG Cell Therapy Pte. Ltd.SCG142, Cyclophosphamide, FludarabinePhase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive CarcinomaHPV-Related Squamous Cell Carcinoma, HPV-Related Cervical Squamous Cell Carcinoma and 5 morePhase 1/2Not yet recruitingNCT06505551
Dec 2026Sapience TherapeuticsST101, Temozolomide, RadiationA Phase 1-2 Study of ST101 in Patients With Advanced Solid TumorsGlioblastoma, Melanoma Stage IV and 12 morePhase 1/2Active not recruitingNCT04478279
Dec 2026Shandong New Time Pharmaceutical Co., LTDCAPEOX, AC591Phase II Clinical Study of AC591 in Preventing Oxaliplatin-Induced Peripheral NeuropathyColorectal AdenomaPhase 2Not yet recruitingNCT06722950
Dec 2026Jiangsu Hengrui MedicineHRS-7535 tabletStudy on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure a…Adults With Heart Failure, Mild Decrease in Ejection Fraction/Preserved Ejection Fraction, and ObesityPhase 2RecruitingNCT06820099
Dec 2026Jiangsu Hengrui MedicineHRS-7058 + SHR-1316, HRS-7058 + SHR-1316 + Platinum-containing doublet chemothe…, HRS-7058 + Cetuximab and 10 moreA Phase II Clinical Study of HRS-7058 in Combination With Antitumor Drugs in Patients With Advanced Malignant TumourAdvanced Malignant TumourPhase 2RecruitingNCT06915142
Dec 2026Jiangsu Hengrui MedicineHRS-7085A Phase 2 Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of HRS-7085 Tablets in Patients With Inflammatory Bowel Dise…Adult Patients With Moderately to Severely Active Ulcerative ColitisPhase 2RecruitingNCT07229950
Dec 2026Shanghai BDgene Co., Ltd.BD111 Injection (investigational new drug), Triple-drugs therapy of HSV-1 stromal keratitisA Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal KeratitisHerpes Simplex Virus Type I Stromal KeratitisPhase 2RecruitingNCT06474442
Dec 2026Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.TQC2731 injectionA Clinical Study of TQC2731 Injection in Patients With Moderate to Severe Chronic Obstructive Pulmonary DiseaseChronic Obstructive Pulmonary DiseasePhase 2Active not recruitingNCT06707883
Dec 2026Jiangsu Hengrui MedicineSHR-7787 injectionA Trial of SHR-7787 Injection in Patients With Advanced Solid TumorsAdvanced Solid TumorsPhase 1/2RecruitingNCT06605222
Dec 2026Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.YD0743Efficacy and Safety of YD0743 Treatment for Sepsis-Associated ARDSSepsisPhase 2RecruitingNCT07413094
Dec 2026Shenyang Sunshine Pharmaceutical Co., LTD.SSGJ-706+XELOX, SSGJ-706+Bevacizumab+XELOX, SSGJ-706+AG and 1 moreA Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal CancersGastric/Gastroesophageal Junction Adenocarcinoma, Metastatic Colorectal Cancer (CRC) and 2 morePhase 2Not yet recruitingNCT07233850
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological MalignanciesGynecological Malignant Tumor, Solid TumorPhase 1/2RecruitingNCT05803018
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, SI-B003A Study of SI-B003 or BL-B01D1+SI-B003 in Patients With Unresectable Locally Advanced or Recurrent Metastatic HER2 Negative Breast CancerBreast CancerPhase 2RecruitingNCT06042894
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, SI-B003A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other S…Head and Neck Squamous Cell CarcinomaPhase 2RecruitingNCT06006169
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-M07D1A Study of BL-M07D1 in Patients With a Variety of Solid Tumors Including Locally Advanced or Metastatic HER2-positive/Low-expressing Urinary…Her2-positive/Low-expression Urinary and Digestive Tract TumorsPhase 1/2RecruitingNCT06031584
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.SI-B001, SI-B003A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell CarcinomaSquamous Cell Carcinoma of Head and NeckPhase 1/2Active not recruitingNCT05668858
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, SI-B003A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Cervical Cancer and Other Gynecological Malignanc…Cervical CancerPhase 2RecruitingNCT05990803
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, SI-B003A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma…Non-small Cell Lung Cancer, Nasopharyngeal CarcinomaPhase 2RecruitingNCT05956587
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, PD-1A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial CarcinomaUrothelial CarcinomaPhase 2RecruitingNCT06405425
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, PD-1 Monoclonal AntibodyA Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Unresectable Locally Advanced or Recurrent Metastatic Triple-negative Breast C…Triple-negative Breast CancerPhase 2RecruitingNCT06471205
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, PD-1 monoclonal antibodyA Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung CancerExtensive-stage Small-cell Lung CancerPhase 2RecruitingNCT06437509
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, SI-B003A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Extensive Stage Small Cell Lung CancerSmall Cell Lung CancerPhase 2RecruitingNCT05924841
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-M07D1A Study of BL-M07D1 in Patients With HER2-Overexpressing or HER2-Mutant Locally Advanced or Metastatic Non-Small Cell Lung CancerNon-small Cell Lung CancerPhase 1/2Active not recruitingNCT06114511
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Locally Advanced or Metastatic Urinary System TumorsUrinary System Tumor, Solid TumorPhase 2RecruitingNCT05785039
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.GNC-035A Study of GNC-035 in Relapsed or Refractory Non-Hodgkin 's Lymphoma and Other Hematological MalignanciesNon-hodgkin's LymphomaPhase 1/2RecruitingNCT06066203
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.SI-B003, BL-B01D1, PD-1 Monoclonal AntibodyA Study of SI-B003, BL-B01D1+SI-B003 and BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Esophageal Cancer…Esophageal Cancer, Gastric Cancer and 1 morePhase 2RecruitingNCT06008054
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.SI-B001, SI-B003A Study of SI-B001+SI-B003± Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung CancerNon-small Cell Lung CancerPhase 1/2Active not recruitingNCT05949606
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-M07D1A Study of BL-M07D1 in Patients With HER2-expressing Recurrent or Metastatic Gynecologic MalignanciesGynecological MalignanciesPhase 1/2RecruitingNCT06131450
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.BL-B01D1, SI-B003A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid TumorsUrothelial Carcinoma, Solid TumorPhase 2RecruitingNCT05965856
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.SI-B001, Paclitaxel, docetaxelA Clinical Study of SI-B001 in Combination With Paclitaxel/Docetaxel in the Treatment of Recurrent and Metastatic HNSCCHead and Neck Squamous Cell CarcinomaPhase 2Active not recruitingNCT05054439
Dec 2026Sichuan Baili Pharmaceutical Co., Ltd.GNC-038A Study of GNC-038 Injection in Patients With Relapsed or Refractory Non-Hodgkin's LymphomaNon-hodgkin's LymphomaPhase 1/2RecruitingNCT05623982
Dec 2026Sichuan Huiyu Pharmaceutical Co., LtdTest product: HYP-2090PTSAPhase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS MutationSafety, Tolerability and 1 morePhase 1/2RecruitingNCT06243354
Dec 2026Sinew Pharma Inc.TYNADOTETo Evaluate the Efficacy and Safety of TYNADOTE® in the Treatment of Acetaminophen OverdoseHepatitisPhase 2RecruitingNCT05557448
Dec 2026Songqi GaoMT218 injectionEvaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer PatientsMRI ScanPhase 1/2RecruitingNCT06262139
Dec 2026Sound Pharmaceuticals, IncorporatedEbselenSPI-1005 in Adults Receiving Cochlear ImplantHearing Loss, Cochlear TraumaPhase 2RecruitingNCT06340633
Dec 2026Stemline Therapeutics, Inc.Elacestrant, AbemaciclibStudy of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast CancerBreast Neoplasms, Brain Neoplasms and 6 morePhase 1/2RecruitingNCT05386108
Dec 2026Step Pharma, SASSTP938A Phase 1/2 Study of STP938 (Dencatistat) for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell LymphomasLymphoma, B-Cell, Lymphoma, T-CellPhase 1/2RecruitingNCT05463263
Dec 2026Sunhawk Vision Biotech, Inc.SHJ002, AtropineA Study of SHJ002 Sterile Ophthalmic Solution for Myopia ControlMyopia, ProgressivePhase 2Active not recruitingNCT06579287
Dec 2026Sunshine Lake Pharma Co., Ltd.HEC585 dose A, HEC585 dose BA Study to Explore the Therapeutic Effect of HEC585 on Delaying Forced Vital Capacity (FVC) Decline and Tolerance in Progressive Fibrosing I…Progressive Fibrosing Interstitial Lung Disease (PF-ILD) / Progressive Pulmonary Fibrosis (PPF)Phase 2RecruitingNCT05139719
Dec 2026Jiangsu Hengrui MedicineSHR-1826；Adebrelimab；SHR-8068；BevacizumabA Phase II Clinical Study of SHR-1826 for Injection in Patients With NSCLCNSCLCPhase 2RecruitingNCT06844474
Dec 2026Jiangsu Hengrui MedicineSHR-A1811, Carboplatin, Bevacizumab and 4 moreA Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian CancerOvarian CancerPhase 1/2RecruitingNCT06840002
Dec 2026SynDevRx, Inc.EvexomostatEvexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast CancerHR+/HER2-negative Breast Cancer, Metastatic Breast CancerPhase 1/2RecruitingNCT05455619
Dec 2026SynerGene Therapeutics, Inc.SGT-53, nab-paclitaxel, GemcitabineStudy of Combined SGT-53 Plus Gemcitabine/Nab-Paclitaxel for Metastatic Pancreatic CancerMetastatic Pancreatic CancerPhase 2Active not recruitingNCT02340117
Dec 2026Taiho Oncology, Inc.TAS-120Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or RearrangementAdvanced Cholangiocarcinoma, FGFR2 Fusions and 1 morePhase 2RecruitingNCT05727176
Dec 2026Technophage, SAEletriptan HBr 40 mgPhase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord InjuryAcute Spinal Cord Injury (SCI)Phase 1/2RecruitingNCT06677229
Dec 2026Tern Therapeutics, LLCTTX-381A Registrational Study of TTX-381 to Treat Vision Loss in CLN2 DiseaseNeuronal Ceroid Lipofuscinosis Type 2Phase 1/2RecruitingNCT05791864
Dec 2026Theralase® Technologies Inc.Ruvidar® (TLD-1433) bladder infusion and PDTIntravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") PatientsNon-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCGPhase 2RecruitingNCT03945162
Dec 2026Thiogenesis Therapeutics, Corp.TTI-0102 (cysteamine-pantetheine disulfide)Pilot Study of TTI-0102 in CystinosisNephropathic Cystinosis, CystinosisPhase 2Not yet recruitingNCT07837726
Dec 2026TiumBio Co., Ltd.TU2218 + KEYTRUDA® (Pembrolizumab)Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid TumorsSolid Tumor, Biliary Tract Cancer and 2 morePhase 1/2RecruitingNCT05784688
Dec 2026TolerogenixX GmbHMICClinical Trial With Donor Modified Immune Cells in Living Donor Kidney TransplantationKidney TransplantationPhase 2RecruitingNCT05365672
Dec 2026Toll Biotech Co. Ltd. (Beijing)TollB-001Safety and Efficacy of TollB-001 Tablets in Moderate to Severe Rheumatoid ArthritisRheumatoid Arthritis (RA)Phase 2RecruitingNCT07408024
Dec 2026Traws Pharma, Inc.TRX-100This is an Early-stage Clinical Trial to Determine a Safe and Effective Dose for Tivoxavir Marboxil in Patients With Mild to Moderate Influe…InfluenzaPhase 2Active not recruitingNCT07371650
Dec 2026UBP Greater China (Shanghai) Co., LtdUB-421, UB-421+chidamideA Proof of Concept Study to Evaluate the Effect of UB-421 in Combination With Chidamide on HIV Viral ReservoirHIV-1-infectionPhase 2Not yet recruitingNCT04985890
Dec 2026VapeAwayVapeAway filter systemThe CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette ReductionAddiction NicotinePhase 2RecruitingNCT07322432
Dec 2026Ventus Therapeutics U.S., Inc.VENT-03A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety …Cutaneous Lupus Erythematosus (CLE), Systemic Lupus Erythematosus and 3 morePhase 2RecruitingNCT07260877
Dec 2026Wuhan Optics Valley Vcanbiopharma Co., Ltd.VUM02 Injection (UC-MSCs)+BAT, The control group with Best Available Therapy (BAT)A Phase I/II Trial of VUM02 Injection for Steroid-refractory Acute Graft-versus-host Disease (SR-aGvHD) TreatmentSteroid-refractory Acute Graft-versus-host DiseasePhase 1/2Not yet recruitingNCT06677255
Dec 2026Xenothera SASXON7FIH XON7 in Advanced/Metastatic Solid TumorsAdvanced Solid Tumor, Metastatic CancerPhase 1/2RecruitingNCT06154291
Dec 2026Zenith EpigeneticsZEN003694, EnzalutamideZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate CancerMetastatic Castration-Resistant Prostate CancerPhase 2RecruitingNCT04986423
Dec 2026Zhejiang Haichang Biotech Co., Ltd.WGI-0301 at MTD/RP2D dose IV infusion, QW, WGI-0301 at MTD/RP2D -1 dose IV infusion, QW, Sorafenib 400 mg PO, BID continuously and 1 morePhase 2 Study of WGI-0301 for Advanced HCCAdvanced Hepatocellular Carcinoma (HCC)Phase 2RecruitingNCT06309485
Dec 2026Zucara Therapeutics Inc.ZT-01, 7 mg, ZT-01, 15 mg, ZT-01, 22 mgA Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 DiabetesType 1 Diabetes Mellitus With HypoglycemiaPhase 2RecruitingNCT05762107
Dec 2026iRegene Therapeutics Co., Ltd.Human Dopaminergic Progenitor CellsThe Safety, Feasibility and Efficacy of NouvNeu001 for Parkinson's DiseaseParkinson Disease (PD)Phase 2Not yet recruitingNCT07028632
Dec 2026jCyte, Inchuman retinal progenitor cells, Mock injectionSafety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)Retinitis PigmentosaPhase 2Active not recruitingNCT06912633
Dec 1, 2026AP Biosciences Inc.AP402 (Part 1 Dose esclation), AP402 (Part 2 Dose Expansion)A Study of AP402 in HER2-Positive Patients With Locally or Advanced Solid TumorsAdvanced Solid TumorPhase 1/2RecruitingNCT06669975
Dec 1, 2026ASTEROGENE Biomedical Co. Ltd.aNPCEvaluatIon of Autologous Nucleus Pulposus Cells (aNPC) in Degenerative Disc DiseaseIntervertebral Disc DegenerationPhase 1/2RecruitingNCT07168603
Dec 1, 2026Beijing Biostar Pharmaceuticals Co., Ltd.Utidelone combined with Bevacizumab, UtideloneUtidelone Injection Combined with Bevacizumab Injection for Non-small Cell Lung Cancer Patients with Brain MetastasesNon-small Cell Lung Cancer Patients with Brain MetastasesPhase 2Not yet recruitingNCT06683703
Dec 1, 2026Biocomposites LtdSTIMULAN VGA Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV …Pressure Ulcer, Stage IV, OsteomyelitisPhase 2RecruitingNCT06283979
Dec 1, 2026Cartesian TherapeuticsDescartes-08Descartes-08 for Patients With Systemic Lupus ErythematosusSystemic Lupus Erythematosus (SLE)Phase 2Active not recruitingNCT06038474
Dec 1, 2026CellARTs Inc.Stem cell, Genetic Screening, Genetic Reprogramming and 1 moreSpermatogonial Differentiation Via Testicular OrganoidInfertility, Male, Gene Abnormality and 1 morePhase 1/2RecruitingNCT06841861
Dec 1, 2026EpicentRx, Inc.AdAPT-001, Checkpoint Inhibitor, ImmuneA Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid TumorsSolid Tumor, Adult, Cancer and 4 morePhase 2Active not recruitingNCT04673942
Dec 1, 2026FindCure Biosciences (ZhongShan) Co., Ltd.FC084CSA+Tislelizumab combination (dose escalation), RP2D of FC084CSA+Tislelizumab combination (dose expansion)A Study of FC084CSA in Combination of Tislelizumab in Patients With Advanced Malignant Solid TumorsAdvanced Malignant Solid TumorsPhase 1/2RecruitingNCT06499350
Dec 1, 2026Intra-IMMUSG Pte LtdPRL3-zumabA Study to Assess Safety and Efficacy of PRL3-Zumab in Patients With Solid TumorsSolid TumorPhase 2Active not recruitingNCT04452955
Dec 1, 2026K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, IncazenosertibA Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal CancerHigh-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal CancerPhase 2RecruitingNCT05128825
Dec 1, 2026Luxa Biotechnology, LLCRPESC-RPE-4WSafety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)Dry Age-related Macular DegenerationPhase 1/2RecruitingNCT04627428
Dec 1, 2026SanofiPandemic flu H5 HA mRNA SD2 vaccineStudy to Evaluate the Safety and the Immunogenicity of a Second Generation Structurally Designed mRNA Vaccine Candidate Against Pandemic Inf…Pandemic Influenza Immunization, Healthy VolunteersPhase 1/2Active not recruitingNCT06907511
Dec 1, 2026Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.FCN-338 + Azacitidine, FCN-338 + erythromycin+ Ara-CFCN-338 in Combination With Azacitidine or Chemotherapy in Myeloid NeoplasmsSafety, Antitumor Activity and 1 morePhase 2Active not recruitingNCT06858618
Dec 3, 2026EisaiE2814, LecanemabA Study of E2814 With Concurrent Lecanemab Treatment in Participants With Early Alzheimer's DiseaseAlzheimer's DiseasePhase 2Active not recruitingNCT06602258
Dec 3, 2026Regeneron PharmaceuticalsREGN7999A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload …Non-Transfusion Dependent Beta-Thalassemia (NTDT)Phase 2Active not recruitingNCT06421636
Dec 5, 2026Haisco Pharmaceutical Group Co., Ltd.HSK39297 200mgQD, HSK39297 300mgQDA Study to Evaluate the Long-Term Safety and Efficacy of HSK39297 Tablets in Primary IgA NephropathyIgA Nephropathy (IgAN)Phase 2RecruitingNCT07616700
Dec 5, 2026Suzhou Forlong Biotechnology Co., LtdFL115+PD-1A Study of FL115 in Combination With a PD-1 Antibody in Advanced Solid TumorsAdvanced Solid TumorsPhase 1/2RecruitingNCT07131202
Dec 8, 2026PfizerRitlecitinibA 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medic…Hidradenitis SuppurativaPhase 2Active not recruitingNCT07228390
Dec 9, 2026SK Bioscience Co., Ltd.Test Drug 1-1 (GBP511 low dose), Test Drug 1-2 (GBP511 mid dose), Test Drug 1-3 (GBP511 high dose) and 6 moreA Phase I/II, Dose-finding Study to Assess the Safety, Reactogenicity, and Immunogenicity of a Broadly Protective Sarbecovirus Vaccine (GBP5…Healthy Participants, SarbecovirusPhase 1/2Active not recruitingNCT07280858
Dec 10, 2026AstraZenecaBaxdrostat/dapagliflozinA Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Particip…Chronic Kidney Disease and HypertensionPhase 2Active not recruitingNCT07222917
Dec 10, 2026Shanghai PharmaceuticalsLT3001 Drug:high dose, LT3001 Drug:low doseEfficacy and Safety of LT3001 on Treating the Acute Ischemic StrokeAcute Ischemic StrokePhase 2RecruitingNCT05686642
Dec 11, 2026GSKMMBExtended Access of Momelotinib in Adults With MyelofibrosisNeoplasms, Post-polycythemia Vera Myelofibrosis (Post-PV MF) and 3 morePhase 2Active not recruitingNCT03441113
Dec 11, 2026Pfizerdisitamab vedotin, pembrolizumabA Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2Urothelial CarcinomaPhase 2RecruitingNCT04879329
Dec 12, 2026Ausper Biopharma Co., Ltd.AHB-137, NA therapyA Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)Chronic Hepatitis BPhase 2RecruitingNCT07137910
Dec 12, 2026Beijing QL Biopharmaceutical Co.,LtdZT006Efficacy and Safety of ZT006 in Overweight and Obese ParticipantsOverweight , ObesityPhase 2Active not recruitingNCT07230132
Dec 12, 2026Shenzhen Salubris PharmaceuticalsSAL0137 Dose 1, SAL0137 Dose 2, SAL0137 Dose 3A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Oral SAL0137 in Adults With Elevated Lp(a) and Increased Risk of Cardiovas…Elevated Lipoprotein(a)Phase 2Not yet recruitingNCT07729475
Dec 14, 2026Bristol-Myers SquibbBMS-986435Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Frac…Heart FailurePhase 2Active not recruitingNCT06122779
Dec 14, 2026LEO PharmaDelgocitinib creamA 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar …Palmoplantar PustulosisPhase 2RecruitingNCT07013201
Dec 14, 2026NovartisAAA617, 68Ga-PSMA-11Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal FunctionMetastatic Castration-Resistant Prostate Cancer (mCRPC)Phase 2Active not recruitingNCT06004661
Dec 14, 2026NovoNNC0662-0419A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or ObesityOverweight, ObesityPhase 2Active not recruitingNCT07184632
Dec 15, 2026Cerus CorporationINTERCEPT Blood System for RBCs, Infusion of autologous radiolabeled RBCsA Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1Healthy SubjectsPhase 2RecruitingNCT07015437
Dec 15, 2026EXACT Therapeutics ASAcoustic Cluster Therapy, Modified FOLFIRINOXAcoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic CancerLocally Advanced Pancreatic AdenocarcinomaPhase 2RecruitingNCT06850623
Dec 15, 2026GV20 TherapeuticsGV20-0251, GV20-0251 and Pembrolizumab [KEYTRUDA®]A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor MalignanciesSolid Tumor, Adult, Refractory Cancer and 5 morePhase 1/2RecruitingNCT05669430
Dec 15, 2026Pll Tx Australia Pty Ltd–A Study to Evaluate the Safety, Efficacy, and Pharmacodynamics of PLL001 in ALS PatientsAmyotrophic Lateral Sclerosis, ALSPhase 1/2Not yet recruitingNCT06513546
Dec 15, 2026PMV Pharmaceuticals, Inc.rezatapopt, pembrolizumabThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)Advanced Solid Tumor, Advanced Malignant Neoplasm and 28 morePhase 1/2RecruitingNCT04585750
Dec 17, 2026SanofiSAR442970A Study to Investigate the Efficacy and Safety of Brivekimig in Adult Participants With Ulcerative ColitisUlcerative ColitisPhase 2Active not recruitingNCT06975722
Dec 17, 2026SanofibrivekimigA Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's DiseaseCrohn's DiseasePhase 2RecruitingNCT06958536
Dec 18, 2026AbbVieMEDI0618A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic MigraineMigrainePhase 2RecruitingNCT06602479
Dec 20, 2026Haisco Pharmaceutical Group Co., Ltd.HSK47388A Phase 2 Study of HSK47388 Tablets to Evaluate the Efficacy and Safety in Patients With Moderate-to-Severe Plaque PsoriasisPlaque PsoriasisPhase 2Not yet recruitingNCT07158268
Dec 22, 2026Boehringer IngelheimBI 1584862A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atr…Geographic AtrophyPhase 2Active not recruitingNCT06769048
Dec 22, 2026Johnson & JohnsonJNJ-64042056A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's DiseaseAlzheimer DiseasePhase 2Active not recruitingNCT06544616
Dec 23, 2026Changchun GeneScience Pharmaceutical Co., Ltd.PEG-rhGH Injection, hGH InjectionA Phase II Study of PEG-rhGH Injection for Short Children Born Small for Gestational Age: Efficacy, Safety, and PharmacokineticsShort Stature Children Born Small for Gestational Age (SGA)Phase 2RecruitingNCT07260500
Dec 23, 2026Cho Pharma Inc.CHO-H01, CHO-H01 at RP2D, LenalidomideA Study to Assess Safety and Efficacy of CHO-H01 as a Single Agent/Combined With Lenalidomide in Subjects With Refractory or Relapsed Non-Ho…Non-Hodgkin LymphomaPhase 1/2Active not recruitingNCT05950165
Dec 23, 2026Fusion PharmaceuticalsFPI-2265FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)Metastatic Castration-resistant Prostate CancerPhase 2Active not recruitingNCT06402331
Dec 23, 2026NovartisAAA617, AAA517, Piflufolastat F 18 and 3 moreA Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPCProstatic NeoplasmPhase 2Active not recruitingNCT05849298
Dec 23, 2026Sanofifrexalimab, brivekimig, rilzabrutinibA Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Foc…Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal LesionPhase 2RecruitingNCT06500702
Dec 24, 2026InxMed (Shanghai) Co., Ltd.IN10018, Pegylated Liposomal DoxorubicinIN10018 in Combination With Pegylated Liposomal Doxorubicin (PLD) vs. Placebo in Combination With PLD for the Treatment of Platinum-resistan…Ovarian Cancer RecurrentPhase 2RecruitingNCT06014528
Dec 24, 2026Nanjing Leads Biolabs Co.,LtdLBL-024 for Injection, Docetaxel Injection, Bevacizumab Injection and 3 moreA Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]Advanced Solid TumourPhase 2RecruitingNCT06783647
Dec 25, 2026CSPC Pharmaceutical GroupGlumetinib tablets, HB1801 (docetaxel, albumin-bound）, DocetaxelA Study to Evaluate the Efficacy and Safety of the Combination of Glumetinib and Docetaxel（Albumin Bound）Verse Docetaxel for the Treatment o…Locally Advanced/Recurrent or Distant Metastasized Non-small Cell Lung Cancer With MET OverexpressionPhase 2Not yet recruitingNCT06525350
Dec 25, 2026PfizerRitlecitinib 50 mg, Ritlecitinib 100 mgA Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.Chronic Spontaneous UrticariaPhase 2RecruitingNCT07219615
Dec 27, 2026AkesoAK139A Study to Evaluate the Efficacy and Safety of AK139 in Participants With AsthmaAsthmaPhase 2Not yet recruitingNCT07436221
Dec 27, 2026Amplexd Therapeutics, Inc.EGCG and Quinine Sulfate Vaginal SuppositoryPhase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic AbnormalitiesHigh-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion and 4 morePhase 2RecruitingNCT07572396
Dec 27, 2026Stemline Therapeutics, Inc.Elacestrant, Alpelisib, Everolimus and 4 moreOpen-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cance…Breast Cancer, Metastatic Breast CancerPhase 1/2Active not recruitingNCT05563220
Dec 28, 2026Beijing InnoCare Pharma Tech Co., Ltd.CM355A Phase I/II Study of CM355 in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL)HematomaPhase 1/2Active not recruitingNCT05210868
Dec 28, 2026Chengdu Origen Biotechnology Co., Ltd.KH631Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)Age-Related Macular DegenerationPhase 1/2RecruitingNCT05672121
Dec 28, 2026Frantz Viral Therapeutics, LLCArtesunateArtesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSILAnal High Grade Squamous Intraepithelial Lesion, Anal Precancerous Condition and 4 morePhase 2Active not recruitingNCT05555862
Dec 28, 2026GSKNiraparibA Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib StudyOvarian Neoplasms, Breast NeoplasmsPhase 2RecruitingNCT04641247
Dec 28, 2026Nanjing Leads Biolabs Co.,LtdLBL-024 for Injection, Etoposide Injection, Carboplatin Injection and 2 moreA Clinical Trial of LBL-024 Combined With Etoposide and Platinum in Patients With Advanced Neuroendocrine CarcinomaAdvanced Neuroendocrine CarcinomaPhase 1/2RecruitingNCT06157827
Dec 29, 2026Arctic TherapeuticsNACASafety, Tolerability and Efficacy of NPI-001 in Patients With Hereditary Cystatin C Amyloid Angiopathy (HCCAA)Hereditary Cystatin C Amyloid Angiopathy (HCCAA), Hemorrhage Brain and 1 morePhase 2Active not recruitingNCT07716865
Dec 29, 2026Regeneron PharmaceuticalsAlirocumabA Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have HypercholesterolemiaHypercholesterolemiaPhase 2Active not recruitingNCT07477704
Dec 29, 2026Suzhou Sanegene Bio Inc.SGB-9768A Study of SGB-9768 in Patients With Complement-mediated Kidney DiseasesIgA Nephropathy (IgAN), C3 Glomerulopathy and 1 morePhase 2Active not recruitingNCT06786338
Dec 30, 20263D Medicines (Sichuan) Co., Ltd.KN035KN035 for dMMR/MSI-H Advanced Solid TumorsSolid TumorPhase 2Active not recruitingNCT03667170
Dec 30, 20264TEEN4 Pharmaceuticals GmbHAK1967 (Invobenitug also known as Procizumab)A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care.Shock, CardiogenicPhase 1/2RecruitingNCT06832722
Dec 30, 2026AkesoAK112, Cadonilimab, nab-paclitaxel, gemcitabine, AK112, nab-paclitaxel, gemcitabine, nab-paclitaxel, gemcitabineAK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic CancerMetastatic Pancreatic Ductal AdenocarcinomaPhase 1/2Active not recruitingNCT06646055
Dec 30, 2026AkesoAK117, AK112, Nab paclitaxel and 1 moreA Study of AK117/AK112 in Metastatic Triple-Negative Breast CancerMetastatic Triple-negative Breast Cancer, Locally Advanced Triple-negative Breast CancerPhase 2Active not recruitingNCT05227664
Dec 30, 2026Allotera TherapeuticsWU-CART-007A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma …T-cell Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaPhase 2RecruitingNCT06514794
Dec 30, 2026Amorphical Ltd.AMOR-1, Crystalline Calcium CarbonateEvaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in AdultsHypoparathyroidismPhase 2Active not recruitingNCT06547151
Dec 30, 2026Astellas PharmaXNW27011XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.Pancreatic Adenocarcinoma Metastatic, Lung Cancer (NSCLC) and 5 morePhase 1/2Active not recruitingNCT06792435
Dec 30, 2026Bionic Sight LLCBS01BS01 in Patients With Retinitis PigmentosaRetinitis PigmentosaPhase 1/2RecruitingNCT04278131
Dec 30, 2026CanariaBio Inc.Oregovomab, NiraparibA Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.Recurrent Ovarian Cancer, Recurrent Epithelial Cancer of Ovary and 5 morePhase 2Active not recruitingNCT05335993
Dec 30, 2026Chengdu Zenitar Biomedical Technology Co., LtdPM 8.4 mg/m^2, PM 11.2 mg/m^2Study of Purinostat Mesylate for Injection in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL)Diffuse Large B Cell Lymphoma，DLBCLPhase 2Active not recruitingNCT05563844
Dec 30, 2026Ganzhou Hemay Pharmaceutical Co., LtdHemay005 tabletsPhase II Study of Hemay005 in Patients With Active Ulcerative ColitisModerate to Severe Ulcerative ColitisPhase 2Active not recruitingNCT05486104
Dec 30, 2026HC Biopharma Inc.HC010HC010 in First-line PD-L1 Positive Advanced NSCLC PatientsNSCLCPhase 2RecruitingNCT07169552
Dec 30, 2026L & L Bio Co., Ltd., Ningbo, ChinaLB1410, LB4330A Study to Evaluate LB1410 in Combination With LB4330 in Patients With Advanced or Metastatic Solid TumorsSolid TumorPhase 1/2RecruitingNCT06468358
Dec 30, 2026Meribank Biotech Co., Ltd.UMC119-06-05Treatment of Chronic Obstructive Pulmonary Disease by Infusion of Allogenic Mesenchymal Stem CellsChronic Obstructive Pulmonary DiseasePhase 2RecruitingNCT06491043
Dec 30, 2026Natco PharmaNRC-2694-A, PaclitaxelStudy to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Hea…Carcinoma, Recurrent and/or Metastatic Head and Neck Squamous Cell CarcinomaPhase 2RecruitingNCT05283226
Dec 30, 2026Neonc Technologies Holdings, INC.NEO100NEO100 and High-Grade MeningiomaResidual, Progressive or Recurrent Grade II or III MeningiomaPhase 2RecruitingNCT05023018
Dec 30, 2026NovartisIptacopan, RituximabIptacopan in Patients With ANCA Associated VasculitisAnti-Neutrophil Cytoplasm Antibodies (ANCA) Associated VasculitisPhase 2Active not recruitingNCT06388941
Dec 30, 2026PfizerARV-471, RibociclibTACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic B…Breast CancerPhase 1/2Active not recruitingNCT05573555
Dec 30, 2026Psyence Australia Pty LtdPsilocybin therapyPsilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment DisorderAdjustment Disorder, Adjustment Disorder With Anxious Mood and 9 morePhase 2RecruitingNCT07072728
Dec 30, 2026S1 Biopharma, Inc.S1B-408Study of S1B-408 in Women With Orgasmic DysfunctionOrgasmic DisorderPhase 2Not yet recruitingNCT06516055
Dec 30, 2026Sellas Life Sciences GroupSLS009, venetoclax, azacitidineStudy of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Dia…Hematologic MalignanciesPhase 1/2RecruitingNCT04588922
Dec 30, 2026Shanghai Henlius BiotechHLX43A Phase II Study to Evaluate the Efficacy and Safety of HLX43 in Patients With Hormone Receptor Positive, HER2 Negative Locally Advanced or …Hormone Receptor Positive HER-2 Negative Breast CancerPhase 2Not yet recruitingNCT07459738
Dec 30, 2026Shanghai Henlius BiotechHLX43 Dose 1;, HLX43 Dose 2;, HLX43 Dose 3;Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Colorecta…Colorectal Cancer (CRC)Phase 2RecruitingNCT07106892
Dec 30, 2026ShionogiS-337395A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Seve…Respiratory Syncytial Virus InfectionsPhase 2RecruitingNCT07214571
Dec 30, 2026Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.SKB264, DocetaxelSKB264 Monotherapy in Selected Subjects With Advanced Solid TumorsSelected Subjects With Advanced Solid TumorsPhase 2Active not recruitingNCT05631262
Dec 30, 2026Supernus Pharmaceuticals, INC.BIS-001ERBIS-001-ER for the Treatment of Adult Focal Impaired Awareness SeizuresFocal Impaired Awareness SeizuresPhase 1/2Active not recruitingNCT03474770
Dec 30, 2026Suzhou Abogen Biosciences Co., Ltd.ABO2011 Injection, ToripalimabPhase Ⅰ/Ⅱ Clinical Study to Evaluate ABO2011 in Advanced Solid TumorsSolid Tumor, AdultPhase 1/2RecruitingNCT06088004
Dec 30, 2026Jiangsu Hengrui MedicineSHR-8068, Adebrelimab, Cisplatin and 2 moreSHR-8068 in Combination With Adebrelimab, Bevacizumab, and Platinum-Based Chemotherapy as First-line Treatment in Patients With Advanced Bil…Biliary Tract CancerPhase 2Active not recruitingNCT06465563
Dec 30, 2026Swedish Orphan BiovitrumPacritinibA Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)VEXAS, VEXAS SyndromePhase 2RecruitingNCT06782373
Dec 30, 2026Teclison Ltd.Nivolumab Injectable Product, Trans-arterial tirapazamine embolizationCombination of TATE and PD-1 Inhibitor in Liver CancerHepatocellular Carcinoma, Gastric CancerPhase 2RecruitingNCT03259867
Dec 30, 2026ThromBio Pty. Ltd.TBO-309: 60 mg, TBO-309: 120 mg, TBO-309: 30 mgSafety, Tolerability and Efficacy of Adjunctive TBO-309 in Reperfusion for Stroke With Tandem OcclusionIschemic Stroke, Tandem OcclusionPhase 2RecruitingNCT06813651
Dec 30, 2026XyloCor Therapeutics, Inc.XC001Epicardial Delivery of XC001 Gene Therapy to Promote Angiogenesis in CAD Patients Undergoing Treatment With CABGCoronary Artery Disease (CAD)Phase 2Not yet recruitingNCT07118449
Dec 31, 2026AkesoAK112, AK117, Carboplatin and 3 moreA Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant TumorsAdvanced Malignant TumorsPhase 1/2Active not recruitingNCT05229497
Dec 31, 2026Allist Pharmaceuticals, Inc.JAB-21822A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C …KRAS P.G12C, Pancreatic Cancer and 1 morePhase 2RecruitingNCT06008288
Dec 31, 2026Asia Cell Therapeutics (Shanghai) Co., Ltd.Human Umbilical Cord Mesenchymal Stem CellsSafety of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Decompensated Hepatitis B CirrhosisDecompensated Liver CirrhosisPhase 1/2Not yet recruitingNCT05948982
Dec 31, 2026AskGene Pharma, Inc.ASKG915, Paclitaxel + Bevacizumab, Fruquintinib and 1 moreA Study of ASKG915 in Patients With Selected Advanced Solid Tumors.Advanced Solid TumorsPhase 1/2RecruitingNCT05867420
Dec 31, 2026Aveta Biomics, Inc.APG-157Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and BevacizumabGlioma, Glioblastoma MultiformePhase 1/2Active not recruitingNCT06011109
Dec 31, 2026Avistone Biotechnology Co., Ltd.Vebreltinib, PLB1004Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKINon-Small-Cell Lung CancerPhase 1/2RecruitingNCT06343064
Dec 31, 2026Azure Biotech Inc.Lasofoxifene TartrateProof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal WomenVulvo Vaginal Atrophy (VVA)Phase 2RecruitingNCT06197568
Dec 31, 2026Beijing Biostar Pharmaceuticals Co., Ltd.Utidelone Capsule 60mg/m2/d, Utidelone capsule 75mg/m2, Utidelone CapsuleUtidelone Capsule Monotherapy for Patients with Advanced Solid TumorsGastric Cancer Adenocarcinoma Metastatic, Ovarian Cancer and 1 morePhase 2Not yet recruitingNCT06730581
Dec 31, 2026Beijing Tuohua Weiye Biotechnology Co., Ltd.Human Umbilical Cord Mesenchymal Stem Cells InjectionClinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B CirrhosisDecompensated Hepatitis B CirrhosisPhase 1/2RecruitingNCT07413549
Dec 31, 2026BicycleTx LimitedBT5528, NivolumabStudy BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 ExpressionAdvanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer and 5 morePhase 1/2Active not recruitingNCT04180371
Dec 31, 2026Bio-Thera SolutionsMonoclonal antibody BAT6026, sodium chloride injectionEvaluate the Safety, Tolerability of BAT6026Dermatitis, AtopicPhase 1/2Active not recruitingNCT06094179
Dec 31, 2026Blueprint Medicines CorpBLU-808Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)Chronic Inducible Urticaria, Chronic Spontaneous UrticariaPhase 2Active not recruitingNCT06931405
Dec 31, 2026Chongqing Precision Biotech Co., LtdBCMA targeted prime CAR-T cellsa Clinical Research of BCMA-Targeted Prime CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma and Plasma Cell DiseaseMultiple Myeloma, Neoplasm, Plasma Cell and 1 morePhase 1/2RecruitingNCT04776330
Dec 31, 2026Chongqing Precision Biotech Co., LtdCD19 and CD22 targeted prime CAR-T cellsa Clinical Research of CD19 and CD22 Targeted Prime CAR-T Cell in Relapsed/Refractory B-ALLB-ALLPhase 1/2RecruitingNCT04781634
Dec 31, 2026Chongqing Precision Biotech Co., LtdBCMA CAR-T cellsBCMA-Targeted CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma and Plasma Cell DiseaseMultiple Myeloma, Neoplasm, Plasma Cell and 1 morePhase 1/2RecruitingNCT04271644
Dec 31, 2026Clearmind Medicine Inc.CMND-100A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) SubjectsAlcohol Use DisorderPhase 1/2RecruitingNCT05913752
Dec 31, 2026E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd.QY201 Tablets(5mg）, QY201 Tablets（10mg）, QY201 Tablets（20mg）A Multicenter, Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of Q…Adult Subjects With Non-Segmental VitiligoPhase 2RecruitingNCT07712523
Dec 31, 2026EL3 Bio, LLC.L2-01 adipose-derived mesenchymal stem cells (MSC)A Double-Blind, Randomized, Placebo-Controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of L2-01 in Subjects With Crohn's…Crohn&Amp;#39;s, Crohn&Amp;#39;s Disease (CD)Phase 2Not yet recruitingNCT07010926
Dec 31, 2026ENCellEN001Evaluate the Safety and Efficacy of EN001 in Patients With Charcot-Marie-Tooth Disease Type 1A(CMT1A) (Phase 1b: Open-label, Dose-escalation…Charcot-Marie-Tooth Disease Type 1APhase 1/2RecruitingNCT06328712
Dec 31, 2026Elixiron Immunotherapeutics (Hong Kong) Ltd.EI-001Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo PatientsNon-segmental VitiligoPhase 2RecruitingNCT07223229
Dec 31, 2026Evopoint Biosciences Inc.XNW28012Study of XNW28012 in Subjects With Advanced Solid Tumors Who Failed Standard TreatmentsAdvanced Solid Tumors, Pancreatic Carcinoma and 2 morePhase 1/2RecruitingNCT06799637
Dec 31, 2026ExcelsiorEX039A Study of Oral EX039 in Subjects with Mild Alzheimer's DiseaseAlzheimer DiseasePhase 2RecruitingNCT05413655
Dec 31, 2026Excyte Biopharma LtdYK012Study of YK012 in B-cell Acute Lymphoblastic LeukemiaB-cell Acute Lymphoblastic LeukemiaPhase 1/2RecruitingNCT06580301
Dec 31, 2026Frantz Viral Therapeutics, LLCArtesunate ointmentArtesunate Ointment for the Treatment of Anal HSIL in HIV-negative ParticipantsAnal High-grade Squamous Intraepithelial Lesion, Anal HSIL and 2 morePhase 2RecruitingNCT06206564
Dec 31, 2026Genfleet Therapeutics (Shanghai) Inc.GFH009, ZanubrutinibA Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCLLarge B-cell LymphomaPhase 1/2RecruitingNCT06375733
Dec 31, 2026GeoVax, Inc.COVID-19 Vaccine, Diagnostic Laboratory Biomarker Analysis, Synthetic MVA-based SARS-CoV-2 Vaccine GEO-CM04S1SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood CancerCOVID-19 Infection, Hematopoietic and Lymphoid System Neoplasm and 3 morePhase 2Active not recruitingNCT04977024
Dec 31, 2026Jiangsu Hengrui MedicineThe SHR-1139 injectionPhase II Clinical Trial of SHR-1139 Injection in Patients With PsoriasisPsoriasisPhase 2RecruitingNCT07719530
Dec 31, 2026Hangzhou Hanx Biopharmaceuticals, Ltd.HX301+/TemozolomideA Phase 2 Study of HX301 in Patients with High-grade GilomaGliomaPhase 1/2RecruitingNCT06703255
Dec 31, 2026Hillhurst Biopharmaceuticals, Inc.HBI-002Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's DiseaseParkinson DiseasePhase 2RecruitingNCT07005180
Dec 31, 2026Roche HoldingAtezolizumab, Tobemstomig, TiragolumabA Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated …Urothelial CancerPhase 2Active not recruitingNCT05645692
Dec 31, 2026Roche HoldingAfimkibartAfimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's DiseaseCrohns DiseasePhase 2Active not recruitingNCT05910528
Dec 31, 2026Imbioray (Hangzhou) Biomedicine Co., Ltd.IBR854, PazopanibA Study of IBR854 Combined With Pazopanib Versus Pazopanib in Advanced Renal Cell CarcinomaRenal Cell Carcinoma (RCC)Phase 2RecruitingNCT07087158
Dec 31, 2026Impact Therapeutics, Inc.IMP9064Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid TumorsSolid Tumor, Advanced Solid TumorPhase 1/2RecruitingNCT05269316
Dec 31, 2026Innovent BiologicsDexamethasone, IBI3003, Lenalidomide and 1 moreA Open-Label Phase in Participants With Multiple MyelomaMultiple MyelomaPhase 2Not yet recruitingNCT07764861
Dec 31, 2026Innovent BiologicsIBI363IBI363 as Neoadjuvant Therapy in Resectable Stage II-III Non-Small Cell Lung CancerResectable Stage II-III Non-small Cell Lung CancerPhase 2Not yet recruitingNCT07402070
Dec 31, 2026Innovent BiologicsIBI302, FaricimabA Study to Evaluate the Efficacy and Safety of IBI302 inSubjects With Diabetic Macular Edema（DME）Diabetic Macular OedemaPhase 2Active not recruitingNCT06908876
Dec 31, 2026Inovio PharmaceuticalsINO-5401, INO-9012, Cemiplimab and 2 moreINO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)GlioblastomaPhase 1/2Active not recruitingNCT03491683
Dec 31, 2026JCR PharmaceuticalsJR-141An Extension Study of JR-141-BR21 in Patients With Mucopolysaccharidosis IIMucopolysaccharidosis IIPhase 2Active not recruitingNCT03708965
Dec 31, 2026Jacobio Pharmaceuticals Co., Ltd.JAB-23E73A Phase I/IIa Study of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene AlterationAdvanced Solid TumorPhase 1/2RecruitingNCT06959615
Dec 31, 2026Jazz PharmaceuticalsZanidatamabA Phase 2 Study of Zanidatamab in Patients With HER2-expressing TumorsBreast Cancer, Gastric Cancer and 10 morePhase 2RecruitingNCT06695845
Dec 31, 2026Jiangsu Alphamab Biopharmaceuticals Co., LtdJSKN033JSKN033 in Chinese Subjects with Advanced Malignant TumorsAdvanced Malignant TumorsPhase 1/2Not yet recruitingNCT06770881
Dec 31, 2026Jiangsu Hengrui MedicineSHR-A1811Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastat…HER2 Expression / Amplification in Patients With Biliary Tract CancerPhase 2Active not recruitingNCT06413745
Dec 31, 2026Kamau Therapeuticsnula-cel Drug ProductGene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell DiseaseSickle Cell DiseasePhase 1/2RecruitingNCT04819841
Dec 31, 2026Lin BioScience, IncLBS-007The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute LeukaemiasRelapsed or Resistant Acute LeukaemiasPhase 1/2RecruitingNCT05756322
Dec 31, 2026Lumosa Therapeutics Co., Ltd.LT3001 Drug ProductA Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVTAcute Ischemic StrokePhase 2Active not recruitingNCT05198323
Dec 31, 2026Mabwell (Shanghai) Bioscience Co., Ltd.9MW2821, Toripalimab9MW2821 Combined With Toripalimab Injection in Subjects With Local Advanced or Metastatic Urothelial CancerAdvanced Urothelial CarcinomaPhase 1/2RecruitingNCT06079112
Dec 31, 2026Mapi Pharma Ltd.Cariprazine Depot, Cariprazine Depot MTD, Oral Cariprazine 3 mg/dayPharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects E…Schizophrenia, Bipolar I Disorder and 1 morePhase 1/2RecruitingNCT07185815
Dec 31, 2026Medicinova IncMN-001MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and HypertriglyceridemiaDiabetes Mellitus, Type 2, Hypertriglyceridemia and 1 morePhase 2Active not recruitingNCT05464784
Dec 31, 2026Mercator MedSystems, Inc.Perivascular dexamethasone, Perivascular shamPerivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVTThrombosis, Deep Vein, Iliofemoral; ThrombosisPhase 2RecruitingNCT04862468
Dec 31, 2026Miltenyi Biomedicine GmbHzamtocabtagene autoleucel (MB-CART2019.1), Cyclophosphamide, Fludarabine and 1 moreDALY II USA/ MB-CART2019.1 for DLBCLRefractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B Cell Lymphoma and 7 morePhase 2RecruitingNCT04792489
Dec 31, 2026OncoC4, Inc.ONC-392, Pembrolizumab, DocetaxelSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCNon Small Cell Lung Cancer, Advanced Solid Tumor and 17 morePhase 1/2Active not recruitingNCT04140526
Dec 31, 2026Ono PharmaceuticalONO-2020A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease DementiaAgitation Associated With Alzheimer's Disease DementiaPhase 2RecruitingNCT06803823
Dec 31, 2026Ostia SciencesSALI-10 lozengeEfficacy of SALI-10 Oral Probiotics in Experimental GingivitisGingivitisPhase 2Active not recruitingNCT07256743
Dec 31, 2026Partner Therapeutics, Inc.zenocutuzumab (MCLA-128)A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)Solid Tumours Harboring NRG1 Fusion, NSCLC Harboring NRG1 Fusion and 2 morePhase 2Active not recruitingNCT02912949
Dec 31, 2026Pell Bio-Med Technology Co., Ltd.CD19-targeted chimeric antigen receptor T-cellPhase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell LymphomaDiffuse Large B Cell Lymphoma, Primary Mediastinal Large B Cell Lymphoma and 3 morePhase 1/2Active not recruitingNCT05326243
Dec 31, 2026PfizerPF-07104091 monotherapy dose escalation, PF-07104091 + palbociclib + fulvestrant, PF-07104091 + palbociclib + letrozole and 4 morePF-07104091 as a Single Agent and in Combination TherapySmall Cell Lung Cancer, Ovarian Cancer and 1 morePhase 2Active not recruitingNCT04553133
Dec 31, 2026Rhizen Pharmaceuticals SATenalisibEfficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)Triple Negative Breast Cancer (TNBC)Phase 2RecruitingNCT06189209
Dec 31, 2026Sano Chemicals IncOCF001 Intravaginal GelBiweekly Long-term Occidiofungin Study for Suppression of Mycotic RecurrenceCandidiasis, VulvovaginalPhase 2RecruitingNCT07521137
Dec 31, 2026Sarepta TherapeuticsSRP-1003 IV Infusion, SRP-1003 SC InjectionStudy of SRP-1003 in Participants With Type 1 Myotonic DystrophyMyotonic Dystrophy 1Phase 1/2Enrolling by invitationNCT06138743
Dec 31, 2026ScinnoHub Pharmaceutical Co., Ltd.Low-dose BT-114143, High-dose BT-14143, Tranexamic Acid (IV)Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty（TKA）Total Knee ArthroplastyPhase 2RecruitingNCT07127042
Dec 31, 2026Shanghai Cell Therapy Group Co.,LtdSuper DC VaccineExploratory Study of Super DC Cell Injection in Preventing Recurrence After Radical Surgery for TumorsSolid Tumor CancerPhase 1/2RecruitingNCT07146672
Dec 31, 2026Shanghai Henlius BiotechHLX43A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Patients With Advanced Gynecological Malignant Tu…Cervical Cancer, Ovarian CancerPhase 2RecruitingNCT06769152
Dec 31, 2026Shanghai Jiaolian Drug Research and Development Co., LtdB013, PaclitaxelA Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.Platinum-resistant Recurrent Ovarian CancerPhase 2RecruitingNCT06434610
Dec 31, 2026Shanghai PharmaceuticalsT3011 high dose, T3011 middle dose, T3011 low doseA Clinical Study of T3011 in Combination With PD-1/PD-L1 Inhibitors in Subjects With Advanced Solid TumorsAdvanced Solid TumorsPhase 1/2RecruitingNCT06214143
Dec 31, 2026Shanghai PharmaceuticalsSPH5030A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients.Biliary Tract or Colorectal Cancer With Her2-positive/MutatedPhase 2RecruitingNCT06434597
Dec 31, 2026Shanghai PharmaceuticalsSPH4336 TabletsEfficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.Breast Cancer Brain MetastasesPhase 2RecruitingNCT05872347
Dec 31, 2026Shanghai PharmaceuticalsSPH4336, CadonilimabA Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors.Advanced Solid TumorsPhase 1/2RecruitingNCT05944224
Dec 31, 2026Shanghai RAAS Blood Products Co., Ltd.SR604An Open-label, Multicenter Phase I/II Clinical Trial to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic/Pharmacodynamic (PK…Hemophilia A, Hemophilia B and 1 morePhase 1/2RecruitingNCT07644832
Dec 31, 2026Shanghai Synvida Biotechnology Co.,Ltd.SV001A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of SV001 in Patients With Idiopathic Pulmonary Fi…Idiopathic Pulmonary Fibrosis(IPF)Phase 2RecruitingNCT07121413
Dec 31, 2026Shenyang Sunshine Pharmaceutical Co., LTD.SSGJ-705, PD-1/L1 inhibitor combined with chemotherapy, SSGJ-705 combined with chemotherapySSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid TumorsLocally Advanced, Recurrent or Metastatic MalignanciesPhase 2RecruitingNCT07022002
Dec 31, 2026ShionogiSivopixant, Acetazolamide, SASS-001Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep ApneaSleep ApneaPhase 2Active not recruitingNCT06776432
Dec 31, 2026Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.KL590586 CapsuleA Study of KL590586 in Patients With Advanced Solid TumorsAdvanced Solid TumorPhase 1/2Active not recruitingNCT05265091
Dec 31, 2026Skingenix, Inc.Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal BurnsBurnsPhase 2RecruitingNCT01297400
Dec 31, 2026Spirovant Sciences, Inc.SP-101 and doxorubicin Cohort 1, SP-101 and doxorubicin Cohort 2A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)Cystic FibrosisPhase 1/2RecruitingNCT06526923
Dec 31, 2026Supernus Pharmaceuticals, INC.SPN-821 2400 mgDouble-blind, Placebo-controlled Study in Adults With Major Depressive DisorderMajor Depressive Disorder (MDD)Phase 2RecruitingNCT07226661
Dec 31, 2026TaiRx, Inc.Nivolumab Injection [Opdivo], CVM-1118CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular CarcinomaHepatocellular Carcinoma, Advanced CancerPhase 2RecruitingNCT05257590
Dec 31, 2026Tarsus Pharmaceuticals, Inc.lotilanerStudy of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE)Ocular RosaceaPhase 2Enrolling by invitationNCT07443202
Dec 31, 2026Tasly Pharmaceutical Group Co., LtdMesenchymal stem cells(HucMSCs), CABGA Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart FailureCoronary Artery Bypass Grafting (CABG), Chronic Heart Failure and 1 morePhase 1/2RecruitingNCT07265349
Dec 31, 2026Tasly Pharmaceutical Group Co., LtdLow dose Jia Shen Tablet, High dose Jia Shen TabletEfficacy and Safety of Jia Shen Tablets in Chronic Heart FailureHeart FailurePhase 2Not yet recruitingNCT06669169
Dec 31, 2026TheiaNova Ltd.Low-dose TGF-B3 and Dexamethasone Sodium Phosphate, High-dose TGF-B3 and Dexamethasone Sodium PhosphateStudy of TN-001 Topical Eyedrops for KeratoconusKeratoconusPhase 1/2Enrolling by invitationNCT07388069
Dec 31, 2026Valenta Pharm JSCGrammidin with anesthetic, Septolete TotalStudy to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment o…Pharyngitis Acute, Pharyngitis and 2 morePhase 2RecruitingNCT06843018
Dec 31, 2026Valenta Pharm JSC4-MUSTEfficacy, Safety, and Tolerability of 4-MUST Tablets in Chronic Cholecystitis and Biliary DyskinesiaChronic Cholecystitis, Biliary DyskinesiaPhase 2RecruitingNCT06842966
Dec 31, 2026Xenothera SASLIS1Polyspecific Antibodies in Lymphoproliferative T-cell DisordersPeripheral T Cells Lymphoma (PTCL)Phase 1/2RecruitingNCT06495723
Dec 31, 2026Zhejiang ACEA Pharmaceutical Co. Ltd.STI-6129Safety and Efficacy Study of An Anti-CD38 Antibody Drug Conjugate in Relapsed or Refractory Multiple MyelomaRelapsed or Refractory Multiple MyelomaPhase 1/2RecruitingNCT05565807

Trials: ClinicalTrials.gov, the U.S. National Library of Medicine’s registry, industry-sponsored studies only. Completion dates are the sponsor’s own estimates and often slip. Advisory committees: the FDA advisory committee calendar. A trial’s primary completion is when its main measurement is done; companies usually report top-line results weeks to months later, and not always. FDA decision dates (PDUFA goal dates) are not here: the FDA does not publish them, and companies announce them only in their own press releases.