• S&P 500 7,659.44 −1.09%
  • Dow Jones 52,002.41 −0.34%
  • Nasdaq 26,713.03 +0.08%
  • VIX 19.99 +21.45%
  • 10-year Treasury 5.09% −0.01
  • Dollar index 121.40 −0.14%
  • WTI crude $101.91 +1.04%

Biotech calendar: March 2027

Industry-sponsored phase 2 and phase 3 trials with an estimated primary completion in March 2027, from ClinicalTrials.gov.

Trial readouts

231 trials: 76 phase 3 (including phase 2/3) and 155 phase 2. Phase 3 first, then by date. Click a column to sort; type to filter.

Primary completionSponsorDrugConditionPhaseStatusRecord
Mar 2027ABX advanced biochemical compounds GmbH[18F]PSMA-1007Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate CancerProstate CancerPhase 3RecruitingNCT06122584
Mar 2027AFT Pharmaceuticals, Ltd.Combogesic® IV (fixed-dose combination containing acetamin…A Study of Combogesic® IV (Intravenous) in Pediatric Patients With Acute PainAcute PainPhase 3RecruitingNCT07225634
Mar 2027AbbVieCariprazineA Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric …Depression, Bipolar I DisorderPhase 3RecruitingNCT04777357
Mar 2027AbbVieRisankizumab SCA Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely …Crohn's DiseasePhase 3Active not recruitingNCT06063967
Mar 2027AbbVieUpadacitinibProgram to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic …Systemic Lupus ErythematosusPhase 3Active not recruitingNCT05843643
Mar 2027Ache Laboratorios Farmaceuticos S.A.Product DNN.63.18.040, Tramal®Efficacy and Safety of DNN.63.18.040 for the Treatment of Moderate to Severe PainAcute PainPhase 3Not yet recruitingNCT07880392
Mar 2027Amicus TherapeuticsCipaglucosidase Alfa, MiglustatZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPDPompe Disease (Late-onset)Phase 3Active not recruitingNCT03911505
Mar 2027Jiangsu Hengrui Medicine–A Study of SHR-1918 In Participants With HypertriglyceridemiaHypertriglyceridemiaPhase 3Active not recruitingNCT07349615
Mar 2027BlueRock Therapeuticsbemdaneprocel, Sham surgeryA Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's DiseaseParkinsons Disease (PD)Phase 3RecruitingNCT06944522
Mar 2027Sino Biopharmaceutical LimitedTQB3473 TabletsA Study of TQB3473 Tablets Compared to Placebo in the Treatment of Adult Primary Immune ThrombocytopeniaPrimary Immune ThrombocytopeniaPhase 3RecruitingNCT06900920
Mar 2027Sino Biopharmaceutical LimitedTQC3721 Suspension for inhalationEvaluation of the Clinical Trial of Inhaled TQC3721 Suspension in Patients With Moderate-to-Severe Chronic Obstructive Pulmonary DiseaseChronic Obstructive Pulmonary DiseasePhase 3Not yet recruitingNCT07147946
Mar 2027Dompé Farmaceutici S.p.ADFL24498, dexamethasone sodium phosphate (DSP) ophthalmic solutionAn Efficacy and Safety Study of DFL24498 in the Treatment of AKCAtopic KeratoconjunctivitisPhase 3RecruitingNCT07395232
Mar 2027Fujian Shengdi Pharmaceutical Co., Ltd.HRS9531 injection, Semaglutide InjectionA Study Comparing the Efficacy and Safety of HRS9531 Injection With Semaglutide Injection in Subjects With ObesityObesityPhase 3Active not recruitingNCT07285902
Mar 2027Grace Science, LLCGS-100Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 DeficiencyNGLY1 DeficiencyPhase 3Active not recruitingNCT06199531
Mar 2027Ionis Pharmaceuticals IncOlezarsenCORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)Severe HypertriglyceridemiaPhase 3Active not recruitingNCT05681351
Mar 2027Jiangsu Hengrui MedicineRezvilutamide Tablets, Enzalutamide Soft CapsulesA Phase III Clinical Study of Rezvilutamide in Patients With Metastatic Hormone-Sensitive Prostate CancerMetastatic Hormone-sensitive Prostate Cancer (mHSPC)Phase 3RecruitingNCT07241416
Mar 2027Madrigal Pharmaceuticals, INC.ResmetiromA Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAEST…Non-Alcoholic Fatty Liver DiseasePhase 3Active not recruitingNCT04951219
Mar 2027MegalabsExperimental: Epoetin alfa Megalabs® Erythropoietin inject…, Active comparator: European Union licenced epoetin alfaComparative Study of Two Recombinant Human Erythropoietin Products in Chronic Kidney Disease PatientsAnemia of Chronic Kidney DiseasePhase 3Not yet recruitingNCT06352138
Mar 2027Merz TherapeuticsXeominA Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic MigraineChronic MigrainePhase 3Active not recruitingNCT07018713
Mar 2027Merz TherapeuticsXeominA Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic MigraineEpisodic MigrainePhase 3Active not recruitingNCT07018700
Mar 2027Ocular Therapeutix, IncSingle intravitreal injection of axitinib hydrogel implant…, Intravitreal injection of axitinib hydrogel implant follow…, Sham/mock procedure of intravitreal injection followed by …A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic RetinopathyNon-Proliferative Diabetic RetinopathyPhase 3RecruitingNCT07235085
Mar 2027Qilu Pharmaceutical Co., Ltd.1.5% QLM3003 ointment, 2% QLM3003 ointmentEfficacy and Safety Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic DermatitisAtopic DermatitisPhase 3RecruitingNCT06880276
Mar 2027Quetzal TherapeuticsQTX-2101 + ATRA, IV arsenic trioxide (ATO) + ATRAPivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic LeukemiaAcute Promyelocytic Leukemia (APL), Acute Promyelocytic Leukaemia and 3 morePhase 3RecruitingNCT07504458
Mar 2027Seattle Project CorporationGRT-C901, GRT-R902, Atezolizumab and 3 moreA Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Canc…Colorectal NeoplasmsPhase 2/3Active not recruitingNCT05141721
Mar 2027Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.TQC2731 injectionClinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal PolypsChronic Rhinosinusitis With Nasal Polyps (CRSwNP)Phase 3RecruitingNCT07107256
Mar 2027Sinovac BiotechSinovac PCV13 lot 1, Sinovac PCV13 lot 2, Sinovac PCV13 lot 3A Lot-to-Lot Consistency Clinical Trial of PCV13Pneumococcal Infectious DiseasesPhase 3Not yet recruitingNCT07832500
Mar 2027Stoke Therapeutics, Inc.zorevunersen, Sham ComparatorA Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet SyndromeDravet SyndromePhase 3Active not recruitingNCT06872125
Mar 2027Jiangsu Hengrui MedicineSHR-A1912 Injection, Rituximab Injection, Gemcitabine Hydrochloride for Injection and 1 moreA Phase 3 Clinical Study of SHR-A1912 Combined With R-GemOx Versus R-GemOx in Diffuse Large B-cell LymphomaDiffuse Large B-cell LymphomaPhase 3Active not recruitingNCT06929624
Mar 2027Swedish Orphan BiovitrumEfanesoctocog alfaStudy to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog AlfaHaemophilia A (Moderate or Severe)Phase 3Active not recruitingNCT06716814
Mar 2027UroGen Pharma Ltd.UGN-104A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial CancerUpper Urinary Tract Urothelial Carcinoma, Urothelial CarcinomaPhase 3RecruitingNCT06774131
Mar 2027Vaxcyte, Inc.31-valent pneumococcal conjugate vaccine, PCV20Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal VaccinationPneumococcal VaccinesPhase 3Active not recruitingNCT07425392
Mar 2027Vaxcyte, Inc.31-valent pneumococcal conjugate vaccine, Seasonal Influenza Vaccine (SIV) (Flublok)A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of AgePneumococcal VaccinesPhase 3Active not recruitingNCT07365826
Mar 2027Vor Biopharma Inc.TelitaciceptA Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)Generalized Myasthenia GravisPhase 3Active not recruitingNCT06456580
Mar 2027Argenx SEEfgartigimod IVEvaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasth…Generalized Myasthenia GravisPhase 2/3RecruitingNCT04833894
Mar 1, 2027Aragon Pharmaceuticals, Inc.Apalutamide, Bicalutamide, GnRH (agonist) and 1 moreAn Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLASProstatic NeoplasmsPhase 3Active not recruitingNCT02531516
Mar 1, 2027EyeBiotech Ltd.Remigromig, RanibizumabA Study of 2 Doses of Remigromig (EYE103) Compared With Ranibizumab (0.5 mg) in Participants With DMEDiabetic Macular Edema (DME)Phase 2/3Active not recruitingNCT06957080
Mar 1, 2027GSKDepemokimabA Study of Depemokimab in Participants of 6 to 11 Years of AgeAsthmaPhase 3RecruitingNCT07671001
Mar 1, 2027NovoCagriSema (Cagrilintide B and Semaglutide I)A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termObesityPhase 3Active not recruitingNCT07011667
Mar 1, 2027Smilebiotek Zhuhai LimitedQA108 granulesQA108 Phase III Study in Subjects With Intermediate AMDIntermediate Age-Related Macular DegenerationPhase 3RecruitingNCT07189169
Mar 1, 2027Zero Point Five TherapeuticsZP5-9676 600 mg dosePhase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676…Soil-Transmitted Helminthiasis (STH)Phase 3RecruitingNCT06128447
Mar 7, 2027Hansoh Pharmaceutical GroupHS-20089, Paclitaxel, Doxorubicin and 1 moreHS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian CancerOvarian CancerPhase 3RecruitingNCT06855069
Mar 8, 2027CelltrionCT-P44(Daratumumab), Darzalex Faspro(Daratumumab)A Study to Compare Pharmacokinetics, Efficacy and Safety of Subcutaneous CT-P44 and Darzalex Faspro in Combination With Lenalidomide and Dex…Refractory or Relapsed Multiple MyelomaPhase 3Active not recruitingNCT06952478
Mar 9, 2027Hangzhou Gensciences Biopharmaceutical Co., Ltd.FRSW107Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) as Prophylactic Treatment.Severe Hemophilia APhase 3Active not recruitingNCT07684898
Mar 9, 2027UCBbimekizumabA Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque PsoriasisModerate to Severe Plaque Psoriasis, Psoriatic ArthritisPhase 3Active not recruitingNCT06506916
Mar 11, 2027Bristol-Myers SquibbNivolumab, IpilimumabA Study of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Participants With Advanced Kidney CancerRenal Cell CarcinomaPhase 3Active not recruitingNCT03873402
Mar 13, 2027Rhythm Pharmaceuticals, Inc.SetmelanotideA Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic Form and 4 morePhase 3RecruitingNCT06760546
Mar 14, 2027Zai Lab (Shanghai) Co., Ltd.ZL-1109 (VRDN-003)A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye DiseaseThyroid Eye Disease (TED)Phase 3Active not recruitingNCT07211776
Mar 16, 2027Takeda Pharmaceutical CompanyTAK-755A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic PurpuraThrombotic Thrombocytopenic Purpura (TTP)Phase 3Active not recruitingNCT04683003
Mar 17, 2027PfizertofacitinibEvaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative ColitisUlcerative ColitisPhase 3Active not recruitingNCT04624230
Mar 19, 2027Applied Biology, Inc.DA-001, Phenylephrine, DA-001 Topical + DA-005 Oral (HIF-1α supplement) and 3 moreClinical Study of DA-001 as a Treatment for Hair Shedding Reduction and Hair Re-GrowthTelogen Effluvium, Female Pattern Hair Loss and 4 morePhase 2/3Not yet recruitingNCT06648850
Mar 22, 2027Regeneron Pharmaceuticalsfianlimab, cemiplimab, relatlimab+nivolumabA Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to…MelanomaPhase 3RecruitingNCT06246916
Mar 25, 2027Johnson & JohnsonGuselkumabA Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's DiseaseFistulizing Crohns Disease, Perianal Crohns DiseasePhase 3Active not recruitingNCT05347095
Mar 25, 2027SanofiFitusiran, Clotting factor concentrates (CFC) or bypassing agents (BPA), Antithrombin concentrate (ATIIIC)A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants Wit…HemophiliaPhase 3Active not recruitingNCT05662319
Mar 26, 2027LundbeckEptinezumabA Study With Eptinezumab in Adolescents (12-17 Years) With Chronic MigraineChronic Migraine in ChildrenPhase 3RecruitingNCT04965675
Mar 26, 2027NovartisIanalumabPhase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS…Systemic Lupus ErythematosusPhase 3Active not recruitingNCT05639114
Mar 26, 2027Shanghai JMT-Bio Inc.JMT101 Injection, Osimertinib tablet, Cisplatin injection and 1 moreJMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung …Local Advanced or Metastatic NSCLCPhase 3Not yet recruitingNCT06380348
Mar 28, 2027Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.quadrivalent recombinant norovirus vaccine (Pichia pastoris)Clinical Trial of Protective Efficacy of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)Acute Gastroenteropathy Due to NorovirusPhase 3Active not recruitingNCT06524947
Mar 30, 2027Hansoh Pharmaceutical GroupHS-20094 Injection, Dulaglutide InjectionA Phase 3 Study of HS-20094 in Patients With T2DMType 2 DiabetesPhase 3Not yet recruitingNCT07156539
Mar 30, 2027Hansoh Pharmaceutical GroupHS-20094 InjectionA Phase 3 Study of HS-20094 in Patients With T2DM Inadequately Controlled With Diet and Exercise AloneType 2 DiabetesPhase 3Not yet recruitingNCT07156500
Mar 30, 2027Shin Poong Pharmaceutical Co. Ltd.SP-8203Efficacy and Safety of SP-8203 (Otaplimastat) in Patients With Acute Ischemic Stroke Receiving Thrombolytic Standard of CareIschemic StrokePhase 3RecruitingNCT06660719
Mar 31, 2027Ascentage Pharma Group InternationalOlverembatinibA Study of Olverembatinib in SDH-deficient GIST.GISTPhase 3RecruitingNCT06640361
Mar 31, 2027Hangzhou Sumgen Biotech Co., Ltd.SG301 Injection, pomalidomide, dexamethasoneA Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractor…Relapsed/Refractory Multiple MyelomaPhase 3RecruitingNCT06508983
Mar 31, 2027Hansoh Pharmaceutical GroupHS-20137A Study of HS-20137 in Participants with Moderate-to-severe Plaque PsoriasisModerate-to-severe Plaque PsoriasisPhase 3Not yet recruitingNCT06844799
Mar 31, 2027Roche HoldingAtezolizumab, Trastuzumab Emtansine, TrastuzumabA Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive…Breast CancerPhase 3Active not recruitingNCT04873362
Mar 31, 2027Roche HoldingSatralizumabA Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquapo…Neuromyelitis Optica Spectrum Disorder, NMOSDPhase 3RecruitingNCT05199688
Mar 31, 2027Kissei PharmaceuticalKPS-0373Confirmatory Study 3 of KPS-0373 in Patients With Spinocerebellar DegenerationSpinocerebellar DegenerationPhase 3Active not recruitingNCT07040137
Mar 31, 2027Natureceuticals Sdn BhdNuvastatic™Evaluation of NuvastaticTM in Reducing Cancer-Related Fatigue in Colon Cancer Patients Undergoing First-Line ChemotherapyFatigue, Colon CancerPhase 3RecruitingNCT07669519
Mar 31, 2027Neuraptive Therapeutics Inc.NTX-001 (PEG-Fusion)This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacera…Peripheral Nerve Injury Upper Limb, Peripheral Nerve Injury (PNI)Phase 3RecruitingNCT06616025
Mar 31, 2027Newron Pharmaceuticals SPAEvenamide 15 mg bidEvenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant SchizophreniaTreatment-resistant SchizophreniaPhase 3RecruitingNCT07184619
Mar 31, 2027NovartisCTL019Study of Out of Specification for TisagenlecleucelB-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell LymphomaPhase 3RecruitingNCT04094311
Mar 31, 2027PfizerRitlecitinib, Ritlecitinib 100 mgA 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental VitiligoVitiligoPhase 3Active not recruitingNCT06163326
Mar 31, 2027Pierre Fabre MedicamentEncorafenib and BinimetinibAdjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation.MelanomaPhase 3Active not recruitingNCT05270044
Mar 31, 2027Regenerative Ocular Immunobiologics LLCd-MAPPS™ Ophthalmic Solution, Matching vehicle controlStudy of d-MAPPS™ Ophthalmic Solution in Adults With Chronic Ocular Graft-Versus-Host Disease (oGVHD)oGVHD, Ocular Graft Versus Host DiseasePhase 3RecruitingNCT07776210
Mar 31, 2027Sinovac BiotechSNA02-48, Human tetanus immunoglobulin (HTIG)A Phase Ⅲ Clinical Study of SNA02-48 InjectionTetanusPhase 3Not yet recruitingNCT07633119
Mar 31, 2027TuHURA Biosciences, Inc./NVIFx-Hu2.0, PembrolizumabPlacebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merke…Advanced Or Metastatic Merkel Cell CarcinomaPhase 2/3RecruitingNCT06947928
Mar 31, 2027ViatrisCenerimodA Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus ErythematosusLupus Erythematosus, SystemicPhase 3Active not recruitingNCT05648500
Mar 20274D Molecular Therapeutics, Inc.4D-150 IVT, Aflibercept IVT4D-150 in Patients With Neovascular (Wet) Age-Related Macular DegenerationNeovascular (Wet) Age-Related Macular DegenerationPhase 1/2RecruitingNCT05197270
Mar 2027AbbVieLivmoniplimab, Budigalimab, Docetaxel and 2 moreStudy to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV…Urothelial CarcinomaPhase 2Active not recruitingNCT06632951
Mar 2027AbbVieABBV-932Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II DisorderBipolar I or II DisorderPhase 2Active not recruitingNCT07220460
Mar 2027Aconcagua Bio, Inc. a wholly owned subsidiary of Structure TherapeuticsACCG-2671First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671ObesityPhase 1/2RecruitingNCT07815678
Mar 2027Actimed Therapeutics Ltd(S)-pindolol benzoate, SemaglutideA Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide …Obesity, Muscle LossPhase 2RecruitingNCT07101939
Mar 2027Addpharma Inc.AD-211-L, AD-211-M, AD-211-H and 1 moreDetermining the Optimal Dose of AD-211 in Patients With Osteoarthritis of the KneeOsteoarthritis of the KneesPhase 2Not yet recruitingNCT07550231
Mar 2027Adneuris Therapeutics, Inc.CebranopadolA Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic PainChronic Pain, Pain and 2 morePhase 2Not yet recruitingNCT07874620
Mar 2027Aligos Therapeutics, Inc.ALG-000184, TDFA Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- …Chronic Hepatitis B InfectionPhase 2Active not recruitingNCT06963710
Mar 2027AllRock Bio, Inc.ROC-101A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disea…Pulmonary Arterial Hypertension (PAH), Pulmonary Hypertension, Interstitial Lung DiseasePhase 2RecruitingNCT07175038
Mar 2027Allarity Therapeutics, Inc.2X-121Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian CancerAdvanced Ovarian CancerPhase 2RecruitingNCT03878849
Mar 2027Allist Pharmaceuticals, Inc.JAB-21822, JAB-3312Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C MutationKRAS P.G12C, Non-small Cell Lung Cancer and 2 morePhase 1/2RecruitingNCT05288205
Mar 2027Arch Biopartners Inc.LSALT PeptideLSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac SurgeryAcute Kidney Injury, Cardiac SurgeryPhase 2RecruitingNCT05879432
Mar 2027Arditus Pte LtdARD001A First-in Human Study of ARD001 in Healthy Volunteers and People With Hemophilia AHemophilia A, Healthy Adult ParticipantsPhase 1/2RecruitingNCT07787091
Mar 2027Aspeya, Inc.ASY202Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multid…MigrainePhase 2RecruitingNCT07646613
Mar 2027Azevan PharmaceuticalsSRX246Inhibition of Aggressive Behavior in Participants With Fragile X SyndromeAggressive Behavior in Fragile X SyndomePhase 2Not yet recruitingNCT07328529
Mar 2027BeOne Medicines Ltd.TacabrutidegA Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell MalignanciesB-cell Malignancy, Marginal Zone Lymphoma and 8 morePhase 1/2RecruitingNCT05006716
Mar 2027Beijing Biostar Pharmaceuticals Co., Ltd.Utidelone capsule 75mg/m2/d QD, Utidelone capsule 40mg/m2/d BID, Utidelone capsule 50mg/m2/d BID and 1 morePhase II Clinical Study of Utidelone Capsule (UTD2) in Patients With Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Canc…Ovarian Cancer, Fallopian Tube Cancer and 1 morePhase 2Not yet recruitingNCT07044349
Mar 2027Beijing InnoCare Pharma Tech Co., Ltd.ICP-488 TabletsEvaluate the Efficacy and Safety of ICP-488 in Subjects With Cutaneous Lupus Erythematosus (CLE) Double-blind StudyCutaneous Lupus Erythematosus (CLE)Phase 2RecruitingNCT07440537
Mar 2027Beijing InnoCare Pharma Tech Co., Ltd.ICP-322Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo NodularisPrurigo Nodularis (PN)Phase 2RecruitingNCT07236099
Mar 2027BioMarin PharmaceuticalVosoritide InjectionA Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone TreatmentNoonan SyndromePhase 2Active not recruitingNCT06668805
Mar 2027Biomea Fusion, Inc.icovamenib 100mgPhase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic TargetsType 2 DiabetesPhase 2Active not recruitingNCT07502495
Mar 2027BonusBio Group LtdBonoFill-IIEnhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-IIBone FracturePhase 1/2RecruitingNCT03024008
Mar 2027Cellid Co., Ltd.BVAC-E6E7 (low level), BVAC-E6E7 (high level), BVAC-E6E7 (RP2D)A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects With HPV Positive HNSCC.Head and Neck Squamous Cell Carcinoma (HNSCC), HPV (Human Papillomavirus)-Associated Carcinoma and 1 morePhase 1/2RecruitingNCT06797986
Mar 2027Cogent Biosciences, Inc.CGT4859A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid TumorsIntrahepatic Cholangiocarcinoma (Icc), Cholangiocarcinoma and 10 morePhase 1/2Active not recruitingNCT06777316
Mar 2027Compugen LtdCOM701, Normal SalineA Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian CancerOvarian Cancer, Ovarian Cancer RecurrentPhase 1/2Active not recruitingNCT06888921
Mar 2027Deciphera Pharmaceuticals, Inc.Inlexisertib, RipretinibA Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced MalignanciesGISTPhase 1/2Active not recruitingNCT05957367
Mar 2027Denali Therapeutics Inc.BIIB122 225 mgSafety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)Parkinson DiseasePhase 2Active not recruitingNCT06602193
Mar 2027Doma Biopharmaceutical(Suzhou)Co., Ltd.DM005A Study of DM005 in Patients With Advanced Solid TumorsCarcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of Head and Neck and 1 morePhase 1/2RecruitingNCT06515990
Mar 2027Edgewise Therapeutics, Inc.Sevasemten Dose 1, Sevasemten Dose 2, Sevasemten Dose 3Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene TherapyDuchenne Muscular DystrophyPhase 2Active not recruitingNCT06100887
Mar 2027Eli Lilly and CompanyMacupatide, EloralintideA Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type …Obesity, Overweight and 1 morePhase 2Active not recruitingNCT07215559
Mar 2027Eli Lilly and CompanySolbinsiranA Study of Solbinsiran (LY3561774) in Participants With Severe HypertriglyceridemiaSevere HypertriglyceridemiaPhase 2RecruitingNCT07269210
Mar 2027Ellipses PharmaEP0031, Platinum chemotherapy, PemetrexedA Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered MalignanciesNSCLCPhase 1/2RecruitingNCT05443126
Mar 2027Evergreen Therapeutics, Inc.EG-007, Pembrolizumab 100 mg/4 mL (25 mg/ml) Injection, Lenvatinib CapsulesSafety Lead-In Study of a Repurposed Drug Added to the Combination of Len Plus PemAdvanced Endometrial CancerPhase 2Not yet recruitingNCT05106127
Mar 2027Faron PharmaceuticalsBexmarilimab, Azacitidine, VenetoclaxA Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hemato…Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia and 2 morePhase 1/2Active not recruitingNCT05428969
Mar 2027Filamon LTDBETA-TT8 ophthalmic gel 3.8% w/vFirst in Human Study of BETA-TT8 in wetAge-related Macular Degeneration (wetAMD)Neovascular (Wet) Age-Related Macular DegenerationPhase 1/2Not yet recruitingNCT07766473
Mar 2027Fujian Shengdi Pharmaceutical Co., Ltd.HRS-4729 Injection, HRS-4729 Injection;A Study to Evaluate the Efficacy and Safety of HRS-4729 Injection in ObesityOverweight or ObesityPhase 2Not yet recruitingNCT07690826
Mar 2027Genmab A/sEpcoritamabA Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relaps…Diffuse Large B-Cell Lymphoma, Classic Follicular LymphomaPhase 2Active not recruitingNCT05451810
Mar 2027Gilead SciencesDomvanalimab, Zimberelimab, Paclitaxel and 1 moreStudy of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Sta…Head and Neck Squamous Cell CarcinomaPhase 2Active not recruitingNCT06727565
Mar 2027Gilead SciencesSacituzumab Govitecan-hziy (SG), Pembrolizumab, Carboplatin and 1 moreStudy of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (…Non-small Cell Lung CancerPhase 2Active not recruitingNCT05186974
Mar 2027Gilead SciencesOral Lenacapavir, Subcutaneous Lenacapavir, Optimized Background Regimen (OBR)Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and ChildrenHIV-1-infectionPhase 2RecruitingNCT06749054
Mar 2027Guangzhou Bio-gene Technology Co., LtdBG1805Phase I Clinical Study: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid LeukemiaLeukemia, Myeloid, AcutePhase 1/2RecruitingNCT06118788
Mar 2027Haisco Pharmaceutical Group Co., Ltd.HSK44459 CreamTrial of HSK44459 Cream for the Management Plaque PsoriasisPsoriasisPhase 1/2Active not recruitingNCT07623486
Mar 2027ImmunityBio, Inc.AnktivaA Study to Examine Anktiva for the Treatment of COVID-19.Long COVID, Long COVID Syndrome and 1 morePhase 2RecruitingNCT07123727
Mar 2027Jiangsu Hengrui MedicineSHR0302 Tablets, SHR0302 Base GelA Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental VitiligoNon-segmental VitiligoPhase 2RecruitingNCT07251595
Mar 2027Jiangsu Hengrui MedicineHRS-4642A Study of HRS-4642 in Combination With Antineoplastic Agents in Advanced Solid TumorsAdvanced Solid TumorsPhase 1/2RecruitingNCT06520488
Mar 2027Keymed Biosciences Co.LtdCM313Study of CM313 in Subject With IgA NephropathyIgA NephropathyPhase 2Not yet recruitingNCT06830395
Mar 2027Kyowa KirinziftomenibA Phase 2 Clinical Study of Ziftomenib in Patients With Relapsed or Refractory NPM1-Mutated Acute Myeloid LeukemiaAcute Myeloid Leukemia (AML)Phase 2RecruitingNCT07623616
Mar 2027MannKind CorporationTechnosphere Insulin, Basal insulinINHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 DiabetesType 1 Diabetes MellitusPhase 2RecruitingNCT07224321
Mar 2027Myosin Therapeutics Inc.MT-125A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated GlioblastomaGlioblastomaPhase 1/2Not yet recruitingNCT07604285
Mar 2027Napo Therapeutics, S.p.A.Crofelemer Powder for Oral SolutionSafety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (C…Short Bowel Syndrome, Malabsorption Syndromes and 3 morePhase 2RecruitingNCT06904872
Mar 2027Nuvation Bio Inc.NUV-1511Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid TumorsAdvanced Solid Tumor, HER2-negative Breast Cancer and 3 morePhase 1/2Active not recruitingNCT06334432
Mar 2027OcugenOCU400 Low Dose, OCU400 Med Dose, OCU400 High Dose and 1 moreStudy to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital AmaurosisRetinitis Pigmentosa, Leber Congenital AmaurosisPhase 1/2Active not recruitingNCT05203939
Mar 2027Omnix Medical LtdOMN6A Clinical Trial to Assess the Safety and PK of OMN6 in HABP or VABP Caused by Acinetobacter Baumannii ComplexHospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial PneumoniaPhase 2RecruitingNCT06087536
Mar 2027PepGen Inc.PGN-EDODM1A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1Myotonic Dystrophy 1Phase 2RecruitingNCT06667453
Mar 2027PhenoNet, Inc.Cromolyn Sodium (34.2 mg BID), Cromolyn Sodium (17.1 mg BID), Riluzole (100 mg)PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALSAmyotrophic Lateral Sclerosis (ALS)Phase 2RecruitingNCT07142291
Mar 2027RDC Clinical Pty LtdTRPTI 300mgGut Microbiome and Metabolic Health StudyHealthy VolunteersPhase 2RecruitingNCT07457723
Mar 2027Retension Pharmaceuticals, Inc.RTN-001A Study of Modified Release RTN-001 In Patients With Uncontrolled HypertensionUncontrolled HypertensionPhase 2RecruitingNCT07142356
Mar 2027Ribotek Biopharmaceuticals (Shandong) Co., LtdRBD5044RBD5044 in Chinese Participants With HypertriglyceridemiaHypertriglyceridemiaPhase 2Active not recruitingNCT07587788
Mar 2027Seaport Therapeutics, Inc.SPT-300A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious D…Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious DistressPhase 2RecruitingNCT07065240
Mar 2027Jiangsu Hengrui MedicineHRS-1893 TabletA Phase II Clinical Trial of HRS-1893 in the Treatment of Heart Failure With Preserved Ejection FractionHeart Failure With Preserved Ejection FractionPhase 2RecruitingNCT07269717
Mar 2027Shanghai Longwood Biopharmaceuticals Co., Ltd.LW231Study of LW231 in Participants With Chronic Hepatitis BChronic HBV InfectionPhase 1/2RecruitingNCT07179575
Mar 2027Shanghai Minwei Biotechnology Co., LtdMWN109 1, MWN109 2, MWN109 3 and 2 morePhase 2 Clinical Study of MWN109 Tablets in Participants With Type 2 Diabetes MellitusType 2 Diabetes Mellitus (T2DM)Phase 2RecruitingNCT07801820
Mar 2027Jiangsu Hengrui MedicineSHR-A2102, Adebrelimab, Cetuximab and 2 moreA Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinom…Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaPhase 1/2RecruitingNCT07059221
Mar 2027TILT Biotherapeutics Ltd.TILT-123, pembrolizumab, pegylated liposomal doxorubicinOncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (…Platinum-refractory Ovarian Carcinoma, Platinum-resistant Ovarian Cancer and 7 morePhase 1/2Active not recruitingNCT05271318
Mar 2027Tarian PharmaTAR-0520 gelTAR-0520 Gel in Hand and Foot SyndromeHand and Foot SyndromePhase 2Not yet recruitingNCT07457671
Mar 2027Twinpig Biolab, Inc.TB511, KeytrudaClinical Trial of TB511 in Advanced Solid TumorsNSCLC, Prostate Cancer and 2 morePhase 1/2Not yet recruitingNCT06400160
Mar 2027Vanda Pharmaceuticals Inc.VCA-894ATreatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual PatientCharcot Marie Tooth Disease (CMT), Neuromuscular Diseases (NMD)Phase 1/2Active not recruitingNCT07223632
Mar 2027Vima TherapeuticsVIM0423A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated DystoniaDystoniaPhase 2RecruitingNCT07304089
Mar 2027VivaCell Biotechnology EspañaEtribnabdione 25 mg BID, Etribnabdione 50 mg BIDEvaluation of Safety, Tolerability and Preliminary Efficacy of Etrinabdione in Patients With Peripheral Arterial DiseasePeripheral Arterial DiseasePhase 2Not yet recruitingNCT06774040
Mar 2027Walden BiosciencesWAL0921Study of WAL0921 in Patients With Glomerular Kidney DiseasesDiabetic Nephropathies, Primary Focal Segmental Glomerulosclerosis and 3 morePhase 2RecruitingNCT06466135
Mar 2027Argenx SEEfgartigimod PH20 SCA Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic SclerosisSystemic Sclerosis (SSc)Phase 2Active not recruitingNCT06655155
Mar 1, 202760 Degrees Pharmaceuticals, INC.TafenoquineOral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for BabesiosisBabesiosisPhase 2RecruitingNCT06207370
Mar 1, 2027Hansoh Pharmaceutical GroupHS-20137An Open-label Study of HS-20137 in Participants With Moderate-to-Severe Plaque PsoriasisModerate-to-severe Plaque PsoriasisPhase 2RecruitingNCT07879885
Mar 1, 2027Shenzhen Salubris PharmaceuticalsSAL0140A Phase II Clinical Trial of Efficacy and Safety of SAL0140 at Different Doses in Patients With Uncontrolled HypertensionUncontrolled HypertensionPhase 2RecruitingNCT07654140
Mar 1, 2027Tharimmune IncNalmefeneTH104 for the Treatment of Pruritus in Primary Biliary CholangitisPruritus, Primary Biliary CholangitisPhase 2Not yet recruitingNCT06733519
Mar 1, 2027Ukko IncUKK-0018UKK-0018 as an Immunotherapeutic for Treatment of Peanut AllergiesPeanut-Induced Anaphylaxis, Peanut AllergyPhase 1/2RecruitingNCT07349212
Mar 1, 2027Vaxine Pty LtdTherapeutic hepatitis B vaccine, Commercial Hepatitis B vaccineA Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus InfectionChronic Hepatitis bPhase 1/2Not yet recruitingNCT03038802
Mar 1, 2027Verona PharmaEnsifentrineEffect of Ensifentrine on Sputum Markers of Inflammation in COPDCOPDPhase 2Active not recruitingNCT05270525
Mar 3, 2027Freya Biosciences ApSFB 301, Chlorhexidine 0.5%, metronidazole 500 mgChlorhexidine and/or Metronidazole Plus FB301 Pre-treatment TrialBacterial Vaginosis (BV)Phase 2RecruitingNCT07481955
Mar 5, 2027Boehringer IngelheimBI 764524, Sham comparator to BI 764524, Aflibercept (Eylea®) - US onlyA Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic RetinopathyDiabetic RetinopathyPhase 2RecruitingNCT06321302
Mar 6, 2027ModernamRNA-1647A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Tran…Cytomegalovirus InfectionPhase 2Active not recruitingNCT05683457
Mar 8, 2027AstraZenecaAZD7760A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis…Staphylococcus AureusPhase 1/2Active not recruitingNCT06749457
Mar 8, 2027PfizerPF-07275315A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe AsthmaAsthmaPhase 2RecruitingNCT06977581
Mar 9, 2027GSKCamlipixantA Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) …Irritable Bowel SyndromePhase 2RecruitingNCT07519395
Mar 10, 2027CSPC Pharmaceutical GroupA zoster mRNA vaccine SYS6017, Active Comparator VaccineImmunogenicity and Safety of SYS6017 in the Participants Aged 40 Years and AboveHerpes ZosterPhase 2Not yet recruitingNCT07354659
Mar 10, 2027GSKMenABCWY vaccineSafety, Tolerability, and Immunogenicity of MenABCWY Administered on Different Dosing Schedules in Healthy AdolescentsMeningitis, MeningococcalPhase 2Active not recruitingNCT05087056
Mar 11, 2027Boehringer IngelheimBI 765423A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Stan…Idiopathic Pulmonary FibrosisPhase 2Active not recruitingNCT07036523
Mar 12, 2027ENA Respiratory Pty LtdINNA-051A Study Assessing Safety, Tolerability, and Efficacy of INNA-051 in Preventing Respiratory Illness Due to Viral Infections in Healthy Adults…Viral Respiratory Infection, Viral Respiratory IllnessesPhase 2RecruitingNCT07222670
Mar 12, 2027Sinocelltech Ltd.SCT650CEfficacy and Safety of SCT650C in Participants With Moderate to Severe Hidradenitis SuppurativaHidradenitis Suppurativa (HS)Phase 2RecruitingNCT07244510
Mar 12, 2027Travere Therapeutics, Inc.SparsentanStudy of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular DiseasesFocal Segmental Glomerulosclerosis, Minimal Change Disease and 3 morePhase 2RecruitingNCT05003986
Mar 12, 2027Vertex PharmaceuticalsVX-264A Safety, Tolerability, and Efficacy Study of VX-264 in Participants With Type 1 DiabetesType 1 DiabetesPhase 1/2Active not recruitingNCT05791201
Mar 13, 2027Otsuka PharmaceuticalSibeprenlimabA Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren'sSjogren DiseasePhase 2Active not recruitingNCT06928142
Mar 14, 2027Beijing BiotechEB-DUO-CAR-NK-CEA/GCC, LymphodepletionDual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal CancerColorectal Cancer, Metastatic Colorectal Adenocarcinoma and 1 morePhase 1/2RecruitingNCT07589517
Mar 14, 2027Beijing BiotechEGFR/HER2 Dual-Target CAR-NK Cells, Fludarabine, CyclophosphamideEGFR/HER2 Dual-Target CAR-NK Cells for Recurrent or Metastatic HNSCCRecurrent or Metastatic Head and Neck Squamous Cell Carcinoma, Biomarker-positive EGFR/HER2- Expressing HNSCCPhase 1/2RecruitingNCT07617805
Mar 14, 2027Beijing BiotechEB-MF-CAR-NK-01, Fludarabine, CyclophosphamideDual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal MesotheliomaMalignant Pleural MesotheliomasPhase 1/2RecruitingNCT07510815
Mar 14, 2027Beijing BiotechEB-DUALNK, Cyclophosphamide, FludarabineDual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian CancerEpithelial Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube or PeritoneumPhase 1/2RecruitingNCT07589543
Mar 14, 2027Beijing BiotechEB-DT-CAR-NK, Fludarabine, CyclophosphamideDual-target CLDN18.2/HER2 CAR-NK Cells for Advanced Gastric/GEJ CancerAdvanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction AdenocarcinomaPhase 1/2RecruitingNCT07551362
Mar 14, 2027Beijing BiotechEB-G3B7-NK dual-target CAR-NK cells, Fludarabine, CyclophosphamideDual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCCAdvanced Hepatocellular Carcinoma (HCC), Metastatic Liver CancerPhase 1/2RecruitingNCT07500220
Mar 14, 2027Beijing BiotechEB-PT-CAR-NK-S, EB-PT-CAR-NK-D, Lymphodepleting chemotherapy and 1 morePRISM-NK: Precision-Matched Allogeneic Single- or Dual-Target CAR-NK Cells for Advanced Solid TumorsAdvanced or Metastatic Solid TumorsPhase 1/2RecruitingNCT07510828
Mar 14, 2027Beijing BiotechDual-target CAR-NK cells, Lymphodepleting chemotherapy, Supportive careDual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLCNon-Small Cell Lung Cancer, Advanced/MetastaticPhase 1/2RecruitingNCT07641023
Mar 14, 2027Beijing BiotechEBNK-1822H2 dual-target CLDN18.2/HER2 CAR-NK cells, Fludarabine, CyclophosphamideDual-Target CLDN18.2/HER2 CAR-NK Cells for Advanced Esophageal AdenocarcinomaRecurrent or Metastatic Esophageal Adenocarcinoma, Biomarker-selected CLDN18.2-positive and/or HER2-positive DiseasePhase 1/2RecruitingNCT07622940
Mar 14, 2027Beijing BiotechEB-HC01 dual-target CARNK cells, Fludarabine, CyclophosphamideDual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract CancerCholangiocarcinoma, Intrahepatic Cholangiocarcinoma and 3 morePhase 1/2RecruitingNCT07641036
Mar 14, 2027Beijing BiotechEB-DTNB-NK, Fludarabine, CyclophosphamideDual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory NeuroblastomaRelapsed Neuroblastoma, Refractory Neuroblastoma and 2 morePhase 1/2RecruitingNCT07502287
Mar 14, 2027Beijing BiotechAutologous anti-CD19 CAR-T cells, intravenous single infus…, Fludarabine, CyclophosphamideSELECT-SLE: Biomarker-Guided CAR-T Target Selection for Refractory LupusREFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS, Lupus NephritisPhase 1/2RecruitingNCT07523542
Mar 14, 2027Beijing BiotechDual-target CAR-NK cells, Lymphodepleting, Supportive careDual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBCBreast Cancer (Advanced/Metastatic), HER2-positive Breast Cancer and 1 morePhase 1/2RecruitingNCT07510802
Mar 14, 2027Beijing BiotechAutologous CD19/CD22 dual-target CAR-T module, Autologous CD19/CD20 dual-target CAR-T module, Autologous BCMA/CD19 dual-target CAR-T module and 5 moreAdaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic MalignanciesRelapsed/Refractory B-cell Acute Lymphoblastic Leukemia, Relapsed/Refractory B-cell Non-Hodgkin Lymphoma or CLL/SLL and 5 morePhase 1/2RecruitingNCT07523555
Mar 14, 2027Carrick Therapeutics LimitedCT7439 Capsules (0.5 mg, 1mg, 3mg, 10mg, 15mg, 20mg)A Modular Phase 1/2 Study With CT7439 in Participants With Solid MalignanciesSolid MalignanciesPhase 1/2RecruitingNCT06600789
Mar 14, 2027Hudson BiotechRetatrutide (LY3437943), Standardized diet and physical activity counseling through…Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are OverweightObesityPhase 2RecruitingNCT07467447
Mar 15, 2027Energenesis Biomedical Co., Ltd.ENERGI-F703EB Cream, Matched vehicle creamA Study to Evaluate ENERGI-F703EB Cream in Epidermolysis BullosaEpidermolysis Bullosa (EB), Junctional Epidermolysis Bullosa and 2 morePhase 2RecruitingNCT07858422
Mar 16, 2027Intra-Cellular Therapies, Inc.ITI-1284 10 mg, ITI-1284 20 mgStudy of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety DisorderGeneralized Anxiety DisorderPhase 2RecruitingNCT06480383
Mar 17, 2027Sino Biopharmaceutical LimitedTQC2938 injectionA Clinical Study to Evaluate the Efficacy and Safety of TQC2938 in Patients With Moderate to Severe Chronic Obstructive Pulmonary DiseaseChronic Obstructive Pulmonary DiseasePhase 2Active not recruitingNCT06789289
Mar 18, 2027Bristol-Myers SquibbBMS-986446Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alz…Alzheimer Disease, Early OnsetPhase 2Active not recruitingNCT06268886
Mar 19, 2027GSKMomelotinib, LuspaterceptStudy of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent MyelofibrosisPrimary Myelofibrosis, Myelofibrosis; Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia MyelofibrosisPhase 2RecruitingNCT06517875
Mar 20, 2027Medipost Co Ltd.SMUP-IA-01(low-dose), SMUP-IA-01(mid-dose), High Hyal PlusEvaluation Safety and Explore Efficacy Long-term Follow-up Study on Subjects Receiving SMUP-IA-01 or Active ControlKnee OsteoarthritisPhase 2Active not recruitingNCT06798727
Mar 22, 2027Merck & Co.Pembrolizumab, Belzutifan, LenvatinibPembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016)Neoplasm MalignantPhase 2Active not recruitingNCT04976634
Mar 23, 2027AstraZenecaTrastuzumab deruxtecanA Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing TumorsPart 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal CancerPhase 2Active not recruitingNCT04482309
Mar 23, 2027Boehringer IngelheimLow dose BI 3812465, Medium dose BI 3812465, High dose BI 3812465A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are ToleratedDiabetic Macular EdemaPhase 1/2RecruitingNCT07553429
Mar 23, 2027Innovent BiologicsIBI3002, DupilumabA Proof-of-Concept Study of IBI3002 in Patients With Moderate to Severe Atopic DermatitisAtopic DermatitisPhase 2RecruitingNCT07399067
Mar 23, 2027NovartisCryptosporidium parvum oocysts (ABO809), EDI048Study Testing the Efficacy, Safety, and Tolerability of EDI048 in Cryptosporidium Infection Model in Healthy AdultsCryptosporidiosisPhase 2RecruitingNCT07249463
Mar 24, 2027PfizerARV-471, AbemaciclibTACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic B…Breast CancerPhase 1/2Active not recruitingNCT05548127
Mar 25, 2027OrthoTrophix, IncTPX-100 200mg, Once weekly for 4 weeks, PBS53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis o…Osteoarthritis (OA) of the KneePhase 2Active not recruitingNCT06865079
Mar 25, 2027Vertex PharmaceuticalsVX-993, PregabalinEvaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral NeuropathyDiabetic Peripheral Neuropathic PainPhase 2RecruitingNCT06619860
Mar 26, 2027IpsenCorabotaseA Study of IPN10200 for the Treatment of Cervical Dystonia in AdultsCervical DystoniaPhase 2RecruitingNCT06937931
Mar 28, 2027CSPC Pharmaceutical GroupSYS6041A Phase I/IIa Study of SYS6041 in Patients With Advanced Solid TumorsAdvanced Solid TumorsPhase 1/2RecruitingNCT07744763
Mar 29, 2027ScinnoHub Pharmaceutical Co., Ltd.SNH-119014 dose 1, SNH-119014 dose 2A Study of SNH-119014 in Adult Participants With Non-transfusion-dependent Thalassemia (NTDT)ThalassemiaPhase 2Not yet recruitingNCT07579949
Mar 30, 2027Galimedix Therapeutics IncGAL-101A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMDGeographic Atrophy of the MaculaPhase 2RecruitingNCT06659549
Mar 30, 2027Jiangsu Topcel-KH Pharmaceutical Co., Ltd.Human umbilical cord mesenchymal stem cells injection, saline solutionSafety and Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells in Preventing Arteriovenous Fistula Stenosis in Patients With End-S…Arteriovenous Fistula StenosisPhase 1/2Not yet recruitingNCT07452822
Mar 30, 2027Sonara HealthSonaraRemotely Observed Methadone Evaluation IIOpioid Use DisorderPhase 2RecruitingNCT06338280
Mar 31, 2027AstraZenecaAZD4360Study for AZD4360 in Participants With Advanced Solid TumoursGastric Cancer, Gastroesophageal Junction Cancer and 2 morePhase 1/2Active not recruitingNCT06921928
Mar 31, 2027BeOne Medicines Ltd.BGB-B2033, Tislelizumab, BevacizumabA Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Meta…Metastatic Hepatocellular Carcinoma, Local Advanced Hepatocellular Carcinoma and 3 morePhase 1/2RecruitingNCT06427941
Mar 31, 2027Beijing Gene Key Life Technology Co., LtdGKL-006 injection, Nab-paclitaxel and GemcitabineA Phase I/IIa Study of GKL-006 Injection in Patients With Advanced Pancreatic CancerAdvanced Pancreatic Cancer, Ductal Adenocarcinoma of PancreasPhase 1/2Active not recruitingNCT07777211
Mar 31, 2027BioMimetix JV, LLCBMX-001, Paclitaxel (Taxol)BMX-001 + Paclitaxel in Adult Patients With Advanced, Recurrent, Metastatic Ovarian or Endometrial CancerOvarian Neoplasms, Endometrial Cancer, Endometrial NeoplasmPhase 1/2Not yet recruitingNCT06620029
Mar 31, 2027BioRay Pharmaceutical Co., Ltd.Zuberitamab 600mg, Zuberitamab 1000mg, cyclosporineA Phase II Study of Zuberitamab Injection in Patients With Primary Membranous NephropathyPrimary Membranous NephropathyPhase 2Active not recruitingNCT06642909
Mar 31, 2027Boehringer IngelheimBI 1291583Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This M…BronchiectasisPhase 2Active not recruitingNCT05846230
Mar 31, 2027CG Oncology, Inc.Cretostimogene GrenadenorepvecPhase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBCHigh-Risk Non-Muscle-Invasive Bladder CancerPhase 2RecruitingNCT06567743
Mar 31, 2027CellCentric Ltd.CCS1477, Pomalidomide, Dexamethasone and 8 moreStudy to Evaluate CCS1477 (Inobrodib) in Haematological MalignanciesHaematological Malignancy, Acute Myeloid Leukemia and 4 morePhase 1/2RecruitingNCT04068597
Mar 31, 2027EisaiE7389-LF, NivolumabA Study of E7389 Liposomal Formulation (E7389-LF) Plus Nivolumab in Participants With Solid TumorSolid NeoplasmsPhase 1/2Active not recruitingNCT04078295
Mar 31, 2027EisaiE7386, Lenvatinib, Doxorubicin and 1 moreA Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid TumorEndometrial Neoplasms, Neoplasms and 3 morePhase 1/2Active not recruitingNCT04008797
Mar 31, 2027Hangzhou Sumgen Biotech Co., Ltd.SG301 InjectionStudy of SG301 for Renal AMR After TransplantationAntibody Mediated RejectionPhase 2Not yet recruitingNCT07764627
Mar 31, 2027Hebei Senlang Biotechnology Inc., Ltd.S1904 CD19 CAR-TAssessment of Senl_B19 CAR-T Cells in Relapsed/Refractory CD19+ B-ALLB-ALLPhase 2RecruitingNCT07244406
Mar 31, 2027Roche HoldingEnglumafusp alfa, Obinutuzumab, Glofitamab and 1 moreA Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab an…Lymphoma, Non-HodgkinPhase 1/2Active not recruitingNCT04077723
Mar 31, 2027Kither Biotech SrlKIT2014A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of KIT2014 in Patients With Moderate to Severe COPDChronic Obstructive Pulmonary Disease (COPD)Phase 1/2RecruitingNCT07668518
Mar 31, 2027Merakris TherapeuticsMTX-001 (human amniotic fluid)MTX-001 for the Treatment of Non-Healing Venous Stasis UlcersVenous Stasis Ulcer, Venous Leg UlcerPhase 2RecruitingNCT04647240
Mar 31, 2027Merck & Co.Posaconazole IV 6 mg/kg, Posaconazole PFS 6 mg/kgPosaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)Invasive Fungal InfectionPhase 2RecruitingNCT04665037
Mar 31, 2027PfizerATM-AVI, BATStudy of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative InfectionsGram-negative Bacterial InfectionsPhase 2RecruitingNCT05639647
Mar 31, 2027RemedyMDMA assisted psychotherapy, PsychotherapyMDMA-Assisted CBCT for PTSD vs CBCT RCTPost Traumatic Stress DisorderPhase 2RecruitingNCT06044675
Mar 31, 2027Satellos Bioscience Inc.SAT-3247Phase 2 Study of SAT-3247 in Pediatric Ambulatory PatientsDuchenne Muscular Dystrophy, Duchenne and 3 morePhase 2Active not recruitingNCT07287189
Mar 31, 2027Shanghai AbelZeta Ltd.Prizloncabtagene autoleucelA Study of C-CAR039 (Prizloncabtagene Autoleucel) in Patients With Relapsed/Refractory Large B-Cell LymphomaRelapsed/Refractory Large B-Cell LymphomaPhase 1/2RecruitingNCT05800977
Mar 31, 2027Shanghai Guangsheng Biopharmaceutical Co., LtdCosiporfin Sodium for injection, DVDMS, Gemcitabine Hydrochloride for Injection, Cisplatin for injectionCosiporfin Sodium for Injection Photodynamic TherapyBiliary Tract Cancers (BTC)Phase 2RecruitingNCT07398339
Mar 31, 2027Shanghai Institute Of Biological ProductsSIBP-A16 injection, Nirsevimab, SIBP-A16 buffer solutionPhase Ib/IIa Clinical Trial of SIBP-A16 Injection in Premature Infants and Full-term InfantsRespiratory Syncytial Virus (RSV)Phase 1/2Not yet recruitingNCT07363837
Mar 31, 2027Tango Therapeutics, Inc.TNG456, abemaciclibSafety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP LossNon Small Cell Lung Cancer, Glioma Glioblastoma Multiforme and 5 morePhase 1/2RecruitingNCT06810544
Mar 31, 2027Teclison Ltd.TATE and pembrolizumab, TAS-102 pill, Regorafenib PillTATE and Pembrolizumab (MK3475) in mCRC and NSCLCColorectal Cancer; Lung CancerPhase 2RecruitingNCT04701476
Mar 31, 2027Urmila DIwekarOpt-IVF, controlOpt-IVF for Personalized Medicine for Normal RespondersIvfPhase 1/2RecruitingNCT07856082
Mar 31, 2027VivusVI-0609, BiCNUA Study of Carmustine With and Without Ethanol in Subjects With LymphomaLymphoma, Non-Hodgkin Lymphoma and 1 morePhase 2RecruitingNCT06915246
Mar 31, 2027Vast TherapeuticsALX1Study on Doses of Inhaled ALX1 in Adults With BronchiectasisBronchiectasis AdultPhase 2Not yet recruitingNCT07731919

Trials: ClinicalTrials.gov, the U.S. National Library of Medicine’s registry, industry-sponsored studies only. Completion dates are the sponsor’s own estimates and often slip. Advisory committees: the FDA advisory committee calendar. A trial’s primary completion is when its main measurement is done; companies usually report top-line results weeks to months later, and not always. FDA decision dates (PDUFA goal dates) are not here: the FDA does not publish them, and companies announce them only in their own press releases.